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September 2016, Vol 176, No. 9, Pages 1241-1412

In This Issue of JAMA Internal Medicine

Highlights

Abstract Full Text
free access
JAMA Intern Med. 2016;176(9):1241-1243. doi:10.1001/jamainternmed.2015.4900
Viewpoint

Time to Eliminate the Step 2 Clinical Skills Examination for US Medical Graduates

Abstract Full Text
JAMA Intern Med. 2016;176(9):1245-1246. doi:10.1001/jamainternmed.2016.3753

This Invited Commentary examines arguments in favor of discontinuing the Step 2 Clinical Skills Examination.

Inside Story

Less Is More

Tithonus Syndrome

Abstract Full Text
JAMA Intern Med. 2016;176(9):1247. doi:10.1001/jamainternmed.2016.3079

Less Is More

A Grateful but Not Passive Patient

Abstract Full Text
JAMA Intern Med. 2016;176(9):1248-1249. doi:10.1001/jamainternmed.2016.3569

Choosing Our Words Wisely

Abstract Full Text
JAMA Intern Med. 2016;176(9):1249-1250. doi:10.1001/jamainternmed.2016.3653
Original Investigation

Incidence of and Risk Factors for Chronic Opioid Use Among Opioid-Naive Patients in the Postoperative Period

Abstract Full Text
free access has multimedia has audio
JAMA Intern Med. 2016;176(9):1286-1293. doi:10.1001/jamainternmed.2016.3298

This analysis of administrative health claims of nearly 19 million privately insured patients evaluates the association between chronic opioid use and surgery.

Editorial

The New Antibiotic Mantra—“Shorter Is Better”

Abstract Full Text
JAMA Intern Med. 2016;176(9):1254-1255. doi:10.1001/jamainternmed.2016.3646

Notice of Retraction: Sato Y, et al. The Prevention of Hip Fracture With Risedronate and Ergocalciferol Plus Calcium Supplementation in Elderly Women With Alzheimer Disease: A Randomized Controlled Trial. Arch Intern Med. 2005;165(15):1737-1742.

Abstract Full Text
JAMA Intern Med. 2016;176(9):1256. doi:10.1001/jamainternmed.2016.3177

An article by Sato et al has been retracted.

Notice of Retraction: Sato Y, et al. Risedronate Sodium Therapy for Prevention of Hip Fracture in Men 65 Years or Older After Stroke. Arch Intern Med. 2005;165(15):1743-1748.

Abstract Full Text
free access
JAMA Intern Med. 2016;176(9):1256. doi:10.1001/jamainternmed.2016.3771

An article by Sato et al has been retracted.

Less Is More

Duration of Antibiotic Treatment in Community-Acquired Pneumonia: A Multicenter Randomized Clinical Trial

Abstract Full Text
free access
JAMA Intern Med. 2016;176(9):1257-1265. doi:10.1001/jamainternmed.2016.3633

This noninferiority trial compares the effects of IDSA/ATS guideline–recommended vs conventional antibiotic treatment duration on symptom and clinical resolution in hospitalized patients with community-acquired pneumonia.

Effect of Sodium Selenite Administration and Procalcitonin-Guided Therapy on Mortality in Patients With Severe Sepsis or Septic Shock: A Randomized Clinical Trial

Abstract Full Text
free access
JAMA Intern Med. 2016;176(9):1266-1276. doi:10.1001/jamainternmed.2016.2514

This randomized clinical trial evaluates the use of high-dose sodium selenite, with or without use of a procalcitonin algorithm to guide therapy, and its association with mortality in patients with severe sepsis.

Associations Between Ventilator Bundle Components and Outcomes

Abstract Full Text
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JAMA Intern Med. 2016;176(9):1277-1283. doi:10.1001/jamainternmed.2016.2427

This cohort study evaluates the associations between individual and collective ventilator bundle components and patient outcomes among consecutive patients undergoing mechanical evaluation.

Sex Differences in Physician Salary in US Public Medical Schools

Abstract Full Text
free access
JAMA Intern Med. 2016;176(9):1294-1304. doi:10.1001/jamainternmed.2016.3284

This study compares the salaries of male and female physicians in academic positions throughout the United States.

Association of Blood Donor Age and Sex With Recipient Survival After Red Blood Cell Transfusion

Abstract Full Text
free access
JAMA Intern Med. 2016;176(9):1307-1314. doi:10.1001/jamainternmed.2016.3324

This longitudinal cohort study analyzes the association of red blood cell donor age and sex with the survival of transfusion recipients.

Health Care Reform

Effect of Generic Competition on Atorvastatin Prescribing and Patients’ Out-of-Pocket Spending

Abstract Full Text
free access
JAMA Intern Med. 2016;176(9):1317-1323. doi:10.1001/jamainternmed.2016.3384

This population-based cohort study evaluates trends in the prescription and cost of generic atorvastatin among patients with commercial insurance coverage.

Out-of-Pocket Spending for Hospitalizations Among Nonelderly Adults

Abstract Full Text
free access
JAMA Intern Med. 2016;176(9):1325-1332. doi:10.1001/jamainternmed.2016.3663

This study uses commercial health insurance claims data to examine changes in out-of-pocket spending for acute care hospitalization from 2000 to 2013 by patients with insurance coverage from various sources.

Association Between Unconventional Natural Gas Development in the Marcellus Shale and Asthma Exacerbations

Abstract Full Text
free access has audio
JAMA Intern Med. 2016;176(9):1334-1343. doi:10.1001/jamainternmed.2016.2436

This nested case-control study evaluates the association of unconventional natural gas development processes with asthma exacerbations.

Comparison of Health and Health Risk Factors Between Lesbian, Gay, and Bisexual Adults and Heterosexual Adults in the United States: Results From the National Health Interview Survey

Abstract Full Text
free access
JAMA Intern Med. 2016;176(9):1344-1351. doi:10.1001/jamainternmed.2016.3432

This study uses National Health Interview Survey data to compare health and health risk factors between lesbian, gay, and bisexual adults and heterosexual adults in the United States.

Association of Reference Pricing for Diagnostic Laboratory Testing With Changes in Patient Choices, Prices, and Total Spending for Diagnostic Tests

Abstract Full Text
free access
JAMA Intern Med. 2016;176(9):1353-1359. doi:10.1001/jamainternmed.2016.2492

This study describes spending on diagnostic lab testing before and after implementation of reference pricing coverage of laboratory services by an employer health plan, and compares the findings with spending in a plan without reference pricing.

Primary Stroke Center Hospitalization for Elderly Patients With Stroke: Implications for Case Fatality and Travel Times

Abstract Full Text
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JAMA Intern Med. 2016;176(9):1361-1368. doi:10.1001/jamainternmed.2016.3919

This cohort study of Medicare beneficiaries with acute stroke examines associations between admission to a primary stroke centers and case fatality, and investigates whether prolonged travel time offsets the association.

Continuity of Care and Health Care Utilization in Older Adults With Dementia in Fee-for-Service Medicare

Abstract Full Text
free access
JAMA Intern Med. 2016;176(9):1371-1378. doi:10.1001/jamainternmed.2016.3553

This cohort study examines associations between medical clinician continuity and health care testing, utilization, and spending of older adults with dementia..

Invited Commentary

Unpacking the Bundle to Lower Rates of Ventilation-Associated Pneumonia: Parts May Be Less Than the Sum

Abstract Full Text
JAMA Intern Med. 2016;176(9):1284-1285. doi:10.1001/jamainternmed.2016.3523

It Is Time for Equal Pay for Equal Work for Physicians—Paging Dr Ledbetter

Abstract Full Text
JAMA Intern Med. 2016;176(9):1305-1306. doi:10.1001/jamainternmed.2016.3289

Blood Donor Demographics and Transfusion Recipient Survival—No Country for Old Men?

Abstract Full Text
JAMA Intern Med. 2016;176(9):1315-1316. doi:10.1001/jamainternmed.2016.3355

Prescription of Brand-Name Medications When Generic Alternatives Are Available—Patently Unfair

Abstract Full Text
JAMA Intern Med. 2016;176(9):1323-1324. doi:10.1001/jamainternmed.2016.3389

Consumer-Oriented Approaches to Cost Containment

Abstract Full Text
JAMA Intern Med. 2016;176(9):1359-1360. doi:10.1001/jamainternmed.2016.3875

Admitting the Patient With Acute Stroke to the Right House—Lessons From the Sorting Hat of Hogwarts

Abstract Full Text
JAMA Intern Med. 2016;176(9):1368-1370. doi:10.1001/jamainternmed.2016.3930

Medical Care When Memory Fails

Abstract Full Text
JAMA Intern Med. 2016;176(9):1378-1379. doi:10.1001/jamainternmed.2016.3566

The Search for Better Patient Handoff Tools

Abstract Full Text
JAMA Intern Med. 2016;176(9):1402-1403. doi:10.1001/jamainternmed.2016.4263
Editor's Note

Health Insurance for Emergency Hospitalization—Isn’t the Point to Pay the Bill?

Abstract Full Text
free access
JAMA Intern Med. 2016;176(9):1332-1333. doi:10.1001/jamainternmed.2016.3672

Health Care for Lesbian, Gay, and Bisexual People Comes Out of the Closet

Abstract Full Text
free access
JAMA Intern Med. 2016;176(9):1352. doi:10.1001/jamainternmed.2016.3828

Teaching Medical Students to Engage Meaningfully and Judiciously With Patient Data

Abstract Full Text
free access
JAMA Intern Med. 2016;176(9):1397. doi:10.1001/jamainternmed.2016.3886
Review

Improving Communication About Serious Illness in Primary Care: A Review

Abstract Full Text
JAMA Intern Med. 2016;176(9):1380-1387. doi:10.1001/jamainternmed.2016.3212

This review discusses the role of primary care clinicians in driving high-quality conversations about goals and priorities for patients with serious and life-threatening illnesses.

Teachable Moment

Access to Prescription Opioids—Primum Non Nocere: A Teachable Moment

Abstract Full Text
JAMA Intern Med. 2016;176(9):1251-1252. doi:10.1001/jamainternmed.2016.3926

This Teachable Moment discusses the how the Centers for Disease Control and Prevention guidelines for opioid prescribing can play a major role in limiting the impact of this epidemic.

Less Is More

Insomnia in the Hospital—Not Just a Bad Dream

Abstract Full Text
JAMA Intern Med. 2016;176(9):1253. doi:10.1001/jamainternmed.2016.2233

This Teachable Moment discusses nonpharmacologic interventions prior to prescribing quetiapine, benzodiazepines, or sedative hypnotic drugs for the short-term treatment of insomnia in older adult patients.

Challenges in Clinical Electrocardiography

Focal ST-Segment Elevation in a Young Man

Abstract Full Text
JAMA Intern Med. 2016;176(9):1388-1389. doi:10.1001/jamainternmed.2016.3526
Research Letter

Less Is More

Off-label Use of Quetiapine in Medical Inpatients and Postdischarge

Abstract Full Text
free access
JAMA Intern Med. 2016;176(9):1390-1391. doi:10.1001/jamainternmed.2016.3309

This study describes safety and efficacy in the use of quetiapine in a prospective cohort of inpatients and the proportion of in-hospital use that is perpetuated on discharge.

Generic Drug Approvals Since the 1984 Hatch-Waxman Act

Abstract Full Text
free access
JAMA Intern Med. 2016;176(9):1391-1393. doi:10.1001/jamainternmed.2016.3411

This study uses US Food and Drug Administration data to identify approved generic drugs manufactured between September 30, 1984, and January 11, 2016 and compares the effects of number of generic drugs associated with brand-name drugs.

Race and Poverty Status as a Risk for Overall Mortality in Community-Dwelling Middle-Aged Adults

Abstract Full Text
free access
JAMA Intern Med. 2016;176(9):1394-1395. doi:10.1001/jamainternmed.2016.3649

This study uses data from the Healthy Aging in Neighborhoods of Diversity across the Life Span study to examine the contributions of sex, race, and socioeconomic differences to overall mortality in middle-aged adults.

Medical Student Use of Electronic Health Records to Track Former Patients

Abstract Full Text
free access
JAMA Intern Med. 2016;176(9):1395-1397. doi:10.1001/jamainternmed.2016.3878

This survey study describes how and why medical students use the electronic health record to follow patients they are no longer caring for.

Less Is More

Use of Antibiotics Among Patients Hospitalized for Exacerbations of Asthma

Abstract Full Text
free access
JAMA Intern Med. 2016;176(9):1397-1400. doi:10.1001/jamainternmed.2016.4050

This study uses medical record data from Premier Alliance to describe the receipt, type, and timing of antibiotic therapy in patients with asthma in 2013 and 2014.

Association of a Web-Based Handoff Tool With Rates of Medical Errors

Abstract Full Text
free access
JAMA Intern Med. 2016;176(9):1400-1402. doi:10.1001/jamainternmed.2016.4258

This cohort study evaluates the effect of a web-based handoff tool on rates of medical errors in adult medical and surgical patients.

Comment & Response

Appropriate Perspective and Context for Newly Approved Medications, Including Flibanserin

Abstract Full Text
JAMA Intern Med. 2016;176(9):1403-1404. doi:10.1001/jamainternmed.2016.3883

Appropriate Perspective and Context for Newly Approved Medications, Including Flibanserin—Reply

Abstract Full Text
JAMA Intern Med. 2016;176(9):1404-1405. doi:10.1001/jamainternmed.2016.3895

Appropriate Perspective and Context for Newly Approved Medications, Including Flibanserin—Reply

Abstract Full Text
JAMA Intern Med. 2016;176(9):1405. doi:10.1001/jamainternmed.2016.3898

Fish Oils and Bleeding—Where Is the Evidence?

Abstract Full Text
JAMA Intern Med. 2016;176(9):1405-1406. doi:10.1001/jamainternmed.2016.3968

Fish Oils and Bleeding—Where Is the Evidence?—Reply

Abstract Full Text
JAMA Intern Med. 2016;176(9):1406-1407. doi:10.1001/jamainternmed.2016.3971

Not All High-Dose Opioid Users Are Addicts

Abstract Full Text
JAMA Intern Med. 2016;176(9):1407. doi:10.1001/jamainternmed.2016.4118

Not All High-Dose Opioid Users are Addicts—Reply

Abstract Full Text
JAMA Intern Med. 2016;176(9):1407. doi:10.1001/jamainternmed.2016.4121

Further Misanalysis of Urinalysis

Abstract Full Text
JAMA Intern Med. 2016;176(9):1407. doi:10.1001/jamainternmed.2016.4503

Further Misanalysis of Urinalysis—Reply

Abstract Full Text
JAMA Intern Med. 2016;176(9):1408. doi:10.1001/jamainternmed.2016.4510

Remaining Questions Concerning Wearable Devices

Abstract Full Text
JAMA Intern Med. 2016;176(9):1408. doi:10.1001/jamainternmed.2016.4750

Remaining Questions Concerning Wearable Devices

Abstract Full Text
JAMA Intern Med. 2016;176(9):1408-1409. doi:10.1001/jamainternmed.2016.4756

Remaining Questions Concerning Wearable Devices—Reply

Abstract Full Text
JAMA Intern Med. 2016;176(9):1409-1410. doi:10.1001/jamainternmed.2016.4762

Critical Flaws in the Validation of the Instant Blood Pressure Smartphone App—A Letter From the App Developers

Abstract Full Text
JAMA Intern Med. 2016;176(9):1410. doi:10.1001/jamainternmed.2016.4753

Critical Flaws in the Validation of the Instant Blood Pressure Smartphone App—A Letter from the App Developers—Reply

Abstract Full Text
JAMA Intern Med. 2016;176(9):1410-1411. doi:10.1001/jamainternmed.2016.4765

Guideline Update for Article on Pharmaceutical Industry–Sponsored Meals

Abstract Full Text
free access
JAMA Intern Med. 2016;176(9):1411. doi:10.1001/jamainternmed.2016.5054
Correction

Reference to Out-of-Date Guideline

Abstract Full Text
free access
JAMA Intern Med. 2016;176(9):1411-1412. doi:10.1001/jamainternmed.2016.5172

Text Missing From the Discussion Section

Abstract Full Text
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JAMA Intern Med. 2016;176(9):1412. doi:10.1001/jamainternmed.2016.4937

Middle Initial Omitted From Author Name

Abstract Full Text
free access
JAMA Intern Med. 2016;176(9):1412. doi:10.1001/jamainternmed.2016.5221

Incorrect Affiliations for Author

Abstract Full Text
free access
JAMA Intern Med. 2016;176(9):1412. doi:10.1001/jamainternmed.2016.5228
JAMA Internal Medicine Masthead

JAMA Internal Medicine

Abstract Full Text
free access
JAMA Intern Med. 2016;176(9):1244. doi:10.1001/jamainternmed.2015.4901
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