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August 2019 - January 1908

Decade

Year

Issue

November 2017, Vol 177, No. 11, Pages 1549-1703

In This Issue of JAMA Internal Medicine

Highlights

Abstract Full Text
free access
JAMA Intern Med. 2017;177(11):1549-1551. doi:10.1001/jamainternmed.2016.6174
Viewpoint

Physician Work Environment and Well-Being

An Appeal for Evidence-Based Resident Duty Hours Reform

Abstract Full Text
JAMA Intern Med. 2017;177(11):1555-1556. doi:10.1001/jamainternmed.2017.4469

This Viewpoint calls for the implementation of evidence-based policies when carying out duty hour reform for resident clinicians in training.

Health Care Policy and Law

The Trump Administration and the Abandonment of Teen Pregnancy Prevention Programs

Abstract Full Text
JAMA Intern Med. 2017;177(11):1557-1558. doi:10.1001/jamainternmed.2017.4873

This Viewpoint discusses the likely effects of the Trump administration’s discontinuation of teen pregnancy prevention programs that have proved to be successful.

The Impending Death of the Patient-Centered Medical Home

Abstract Full Text
JAMA Intern Med. 2017;177(11):1559-1560. doi:10.1001/jamainternmed.2017.4651

This Viewpoint uses the example of a struggling high-functioning patient-centered medical home (PCMH) in North Carolina to argue on behalf of more government investment in high-functioning PCMH practices.

  • Invited Commentary
    Saving Primary Care
Perspective

I’ve Had a Vision of Improved Primary Care

Abstract Full Text
JAMA Intern Med. 2017;177(11):1563-1564. doi:10.1001/jamainternmed.2017.4020

Saying Goodbye

Abstract Full Text
JAMA Intern Med. 2017;177(11):1565. doi:10.1001/jamainternmed.2017.4017
Editorial

New (Very High) Prices on Old Drugs

Abstract Full Text
JAMA Intern Med. 2017;177(11):1568. doi:10.1001/jamainternmed.2017.3775
Original Investigation

Research and Development Spending to Bring a Single Cancer Drug to Market and Revenues After Approval

Abstract Full Text
free access has audio
JAMA Intern Med. 2017;177(11):1569-1575. doi:10.1001/jamainternmed.2017.3601

This analysis of US Securities and Exchange Commission filings provides a contemporary estimate of research and development spending to develop 10 new cancer drugs.

Less Is More

Clinician-Level Predictors for Ordering Low-Value Imaging

Abstract Full Text
free access has active quiz
JAMA Intern Med. 2017;177(11):1577-1585. doi:10.1001/jamainternmed.2017.4888

This study identified characteristics that made clinicians more likely to order low-value imaging tests for patients with low-back pain and headache.

Effect of a Game-Based Intervention Designed to Enhance Social Incentives to Increase Physical Activity Among Families: The BE FIT Randomized Clinical Trial

Abstract Full Text
free access
JAMA Intern Med. 2017;177(11):1586-1593. doi:10.1001/jamainternmed.2017.3458

This randomized clinical trial tests the effectiveness of a gamification intervention designed using insights from behavioral economics to enhance social incentives within families to increase physical activity.

Patients’ Experiences With Communication-and-Resolution Programs After Medical Injury

Abstract Full Text
free access has audio
JAMA Intern Med. 2017;177(11):1595-1603. doi:10.1001/jamainternmed.2017.4002

This interview study explores communication-and-resolution programs to understand aspects of institutional responses to patient injury that promoted and impeded reconciliation among the injured patients and family members.

Malignant Neoplasms in Patients With Rheumatoid Arthritis Treated With Tumor Necrosis Factor Inhibitors, Tocilizumab, Abatacept, or Rituximab in Clinical Practice: A Nationwide Cohort Study From Sweden

Abstract Full Text
free access
JAMA Intern Med. 2017;177(11):1605-1612. doi:10.1001/jamainternmed.2017.4332

This national register–based study of the public health care system in Sweden assesses the risk of incident malignant neoplasms in patients with rheumatoid arthritis treated with biological disease-modifying antirheumatic drugs.

Lung Cancer Mortality Associated With Smoking and Smoking Cessation Among People Living With HIV in the United States

Abstract Full Text
free access
JAMA Intern Med. 2017;177(11):1613-1621. doi:10.1001/jamainternmed.2017.4349

This validated microsimulation model evaluates the risk of lung cancer death by smoking exposure for persons living with human immunodeficiency virus.

Coronary Computed Tomography Angiography vs Functional Stress Testing for Patients With Suspected Coronary Artery Disease: A Systematic Review and Meta-analysis

Abstract Full Text
free access has active quiz
JAMA Intern Med. 2017;177(11):1623-1631. doi:10.1001/jamainternmed.2017.4772

This systematic review and meta-analysis compares the clinical effectiveness of coronary computed tomography angiography with that of functional stress testing for patients with suspected coronary artery disease.

Effect of Promoting High-Quality Staff Interactions on Fall Prevention in Nursing Homes: A Cluster-Randomized Trial

Abstract Full Text
free access
JAMA Intern Med. 2017;177(11):1634-1641. doi:10.1001/jamainternmed.2017.5073

This cluster-randomized trial tests whether a complexity science–based staff training intervention promoting high-quality staff interactions improves the impact of an evidence-based falls quality improvement program.

Supplemental Nutrition Assistance Program (SNAP) Participation and Health Care Expenditures Among Low-Income Adults

Abstract Full Text
free access
JAMA Intern Med. 2017;177(11):1642-1649. doi:10.1001/jamainternmed.2017.4841

This cohort study evaluates the association between participation in the SNAP program and reduced health care expenditures.

Association of Thyroid Function With Life Expectancy With and Without Cardiovascular Disease: The Rotterdam Study

Abstract Full Text
free access
JAMA Intern Med. 2017;177(11):1650-1657. doi:10.1001/jamainternmed.2017.4836

This study uses the Rotterdam Study cohort to assess the association of thyroid function with total life expectancy and life expectancy with and without cardiovascular disease among euthyroid individuals.

Invited Commentary

Health Care Policy and Law

Saving Primary Care

Abstract Full Text
JAMA Intern Med. 2017;177(11):1560-1562. doi:10.1001/jamainternmed.2017.4991

The Unrecognized Challenges of the Patient-Physician Relationship

Abstract Full Text
JAMA Intern Med. 2017;177(11):1566-1567. doi:10.1001/jamainternmed.2017.5132

Health Care Policy and Law

A Much-Needed Corrective on Drug Development Costs

Abstract Full Text
has audio
JAMA Intern Med. 2017;177(11):1575-1576. doi:10.1001/jamainternmed.2017.4997

It’s All in the Game—The Uses of Gamification to Motivate Behavior Change

Abstract Full Text
JAMA Intern Med. 2017;177(11):1593-1594. doi:10.1001/jamainternmed.2017.4798

Communication-and-Resolution Programs: The Jury Is Still Out

Abstract Full Text
JAMA Intern Med. 2017;177(11):1603-1604. doi:10.1001/jamainternmed.2017.5087

Coronary Computed Tomographic Angiography—The First Test for Evaluating Patients With Chest Pain?

Abstract Full Text
JAMA Intern Med. 2017;177(11):1631-1632. doi:10.1001/jamainternmed.2017.5089

Health Care Reform

Putting a Small Number of Health Care Plan Choices in Perspective: Markets and Marketing Matters

Abstract Full Text
JAMA Intern Med. 2017;177(11):1686-1687. doi:10.1001/jamainternmed.2017.4993
Editor's Note

If We Are Smart Enough to Stop HIV From Replicating, Why Can’t We Help People to Stop Smoking?

Abstract Full Text
JAMA Intern Med. 2017;177(11):1622. doi:10.1001/jamainternmed.2017.4365
Special Communication

Health Care Policy and Law

Determinants of Market Exclusivity for Prescription Drugs in the United States

Abstract Full Text
JAMA Intern Med. 2017;177(11):1658-1664. doi:10.1001/jamainternmed.2017.4329

This Special Communication reviews the peer-reviewed medical and health policy literature to identify studies that described the different types of patent protection and regulatory exclusivities that shield brand-name prescription drugs from competition and help to sustain high drug prices.

Health Care Policy and Law

Strategies That Delay Market Entry of Generic Drugs

Abstract Full Text
JAMA Intern Med. 2017;177(11):1665-1669. doi:10.1001/jamainternmed.2017.4650

This Special Communication examines ways that the federal government can combat attempts by manufacturers of brand-name drugs to forestall generic competition.

Teachable Moment

Less Is More

Nil per Os Orders for Imaging: A Teachable Moment

Abstract Full Text
JAMA Intern Med. 2017;177(11):1670-1671. doi:10.1001/jamainternmed.2017.3943

This Teachable Moment highlights how the use of nil per os orders can lead to complications.

Less Is More

Basal Cell Carcinoma in an Elderly Man

Abstract Full Text
JAMA Intern Med. 2017;177(11):1672. doi:10.1001/jamainternmed.2017.4006

This Teachable Moment discusses the importance of discussions of risks, benefits, and the range of possible outcomes in patients with limited life expectancy.

Challenges in Clinical Electrocardiography

Tachyarrhythmia Onset Captured on Telemetry Deciphers the Diagnosis

Abstract Full Text
JAMA Intern Med. 2017;177(11):1673-1675. doi:10.1001/jamainternmed.2017.3328

Narrow-Complex Tachycardia in a Woman With a 20-Year History of Supraventricular Tachycardia

Abstract Full Text
JAMA Intern Med. 2017;177(11):1676-1678. doi:10.1001/jamainternmed.2017.4785
Research Letter

Possible Insufficiency of Generic Price Competition to Contain Prices for Orally Administered Anticancer Therapies

Abstract Full Text
free access
JAMA Intern Med. 2017;177(11):1679-1680. doi:10.1001/jamainternmed.2017.2788

This study traces the use of the anticancer drug capecitabine through its loss of patent protection to evaluate the effect of generic pricing on the cost of oral anticancer drugs.

Trends and Characteristics of US Medicare Spending on Repository Corticotropin

Abstract Full Text
free access
JAMA Intern Med. 2017;177(11):1680-1682. doi:10.1001/jamainternmed.2017.3631

This study uses Medicare Drug Spending Dashboard data to estimate the cost of repository corticotropin to the Medicare program and assess its within-specialty prescribing patterns.

Trends and Disparities in the Number of Self-reported Healthy Older Adults in the United States, 2000 to 2014

Abstract Full Text
free access
JAMA Intern Med. 2017;177(11):1683-1684. doi:10.1001/jamainternmed.2017.4357

This study examines widening disparities in health from representative data in the rate of healthy older adults from 2000 to 2014.

Health Care Reform

Association Between Number of Insurers and Premium Rates in the Affordable Care Act Marketplace

Abstract Full Text
free access
JAMA Intern Med. 2017;177(11):1684-1686. doi:10.1001/jamainternmed.2017.4780

This study uses publicly available Marketplace health plan data from 2016 and 2017 to examine whether premium growth in monopoly markets with a declining number of insurers differs from that in markets having a stable number of insurers.

Less Is More

Evaluation of a Trainee-Led Project to Reduce Inappropriate Proton Pump Inhibitor Infusion in Patients With Upper Gastrointestinal Bleeding: Skip the Drips

Abstract Full Text
free access
JAMA Intern Med. 2017;177(11):1687-1689. doi:10.1001/jamainternmed.2017.4851

This trainee-led quality improvement study evaluates the use of the Culture, Oversight, Systems Change, Training framework to reduce inappropriate proton pump inhibitor infusions in patients with upper gastrointestinal bleeding.

Utilization, Cost, and Outcome of Branded vs Compounded 17-Alpha Hydroxyprogesterone Caproate in Prevention of Preterm Birth

Abstract Full Text
free access
JAMA Intern Med. 2017;177(11):1689-1690. doi:10.1001/jamainternmed.2017.5017

This study compares the utilization, cost, and outcome data from an insurance claims database to determine the difference in treatment efficacy between the branded and compounded versions of 17-alpha hydroxyprogesterone caproate.

Comment & Response

Increasing Survival in Patients With Congenital Heart Disease—A Glass Half Full or Half Empty?

Abstract Full Text
JAMA Intern Med. 2017;177(11):1690-1691. doi:10.1001/jamainternmed.2017.4821

Natural and Unnatural History

Abstract Full Text
JAMA Intern Med. 2017;177(11):1691-1692. doi:10.1001/jamainternmed.2017.4818

Maternal β-Blocker Use and Fetal Cardiac Anomalies

Abstract Full Text
JAMA Intern Med. 2017;177(11):1692. doi:10.1001/jamainternmed.2017.4894

Maternal β-Blocker Use and Fetal Cardiac Anomalies—Reply

Abstract Full Text
JAMA Intern Med. 2017;177(11):1692-1693. doi:10.1001/jamainternmed.2017.4900

Thyroid Dysfunction in Torsades de Pointes

Abstract Full Text
JAMA Intern Med. 2017;177(11):1693. doi:10.1001/jamainternmed.2017.4897

Thyroid Dysfunction in Torsades de Pointes—Reply

Abstract Full Text
JAMA Intern Med. 2017;177(11):1693-1694. doi:10.1001/jamainternmed.2017.4903

Intensive Blood Pressure Control in Autosomal Dominant Polycystic Kidney Disease—How Safe Is It?

Abstract Full Text
JAMA Intern Med. 2017;177(11):1694. doi:10.1001/jamainternmed.2017.4907

Omission of Data and Errors in Meta-analysis

Abstract Full Text
JAMA Intern Med. 2017;177(11):1694-1695. doi:10.1001/jamainternmed.2017.5327

Intensive Blood Pressure Control in Autosomal Dominant Polycystic Kidney Disease—How Safe Is It?—Reply

Abstract Full Text
JAMA Intern Med. 2017;177(11):1695-1696. doi:10.1001/jamainternmed.2017.4925

The Need for Better Data Breach Statistics

Abstract Full Text
JAMA Intern Med. 2017;177(11):1696. doi:10.1001/jamainternmed.2017.4913

The Need for Better Data Breach Statistics—Reply

Abstract Full Text
JAMA Intern Med. 2017;177(11):1696-1697. doi:10.1001/jamainternmed.2017.4929

Considerations for County-Level Inequalities in Life Expectancy

Abstract Full Text
JAMA Intern Med. 2017;177(11):1697-1698. doi:10.1001/jamainternmed.2017.5830

Perplexing Conclusions Concerning Heat-Not-Burn Tobacco Cigarettes

Abstract Full Text
JAMA Intern Med. 2017;177(11):1698-1699. doi:10.1001/jamainternmed.2017.5840

Considerations for County-Level Inequalities in Life Expectancy—Reply

Abstract Full Text
JAMA Intern Med. 2017;177(11):1698. doi:10.1001/jamainternmed.2017.5858

Perplexing Conclusions Concerning Heat-Not-Burn Tobacco Cigarettes

Abstract Full Text
JAMA Intern Med. 2017;177(11):1699. doi:10.1001/jamainternmed.2017.5843

Perplexing Conclusions Concerning Heat-Not-Burn Tobacco Cigarettes—Reply

Abstract Full Text
JAMA Intern Med. 2017;177(11):1699-1700. doi:10.1001/jamainternmed.2017.5861

Sample Size Matters When Drawing Conclusions on Alternate-Day Fasting Diet

Abstract Full Text
JAMA Intern Med. 2017;177(11):1700-1701. doi:10.1001/jamainternmed.2017.5850

Sample Size Matters When Drawing Conclusions on Alternate-Day Fasting Diet—Reply

Abstract Full Text
JAMA Intern Med. 2017;177(11):1701. doi:10.1001/jamainternmed.2017.5866

Women Also Use 5α-Reductase Inhibitors

Abstract Full Text
JAMA Intern Med. 2017;177(11):1701-1702. doi:10.1001/jamainternmed.2017.6087

Notice of Retraction and Replacement: Colla et al. Association between Medicare accountable care organization implementation and spending among clinically vulnerable beneficiaries. JAMA Internal Medicine. 2016;176(8):1167-1175

Abstract Full Text
JAMA Intern Med. 2017;177(11):1702-1703. doi:10.1001/jamainternmed.2017.4130

Notice of Retraction and Replacement. Colla et al. Association between Medicare accountable care organization implementation and spending among clinically vulnerable beneficiaries. JAMA Internal Medicine. 2016;176(8):1167-1175

Women Also Use 5α-Reductase Inhibitors—Reply

Abstract Full Text
JAMA Intern Med. 2017;177(11):1702. doi:10.1001/jamainternmed.2017.6090
Correction

Omission of Data and Errors in Meta-analysis

Abstract Full Text
free access
JAMA Intern Med. 2017;177(11):1703. doi:10.1001/jamainternmed.2017.5375

Typographical Errors in the Table

Abstract Full Text
free access
JAMA Intern Med. 2017;177(11):1703. doi:10.1001/jamainternmed.2017.6218

Typographical Error in Reports of a P Value

Abstract Full Text
free access
JAMA Intern Med. 2017;177(11):1703. doi:10.1001/jamainternmed.2017.6352

Error in Text and Table Footnote

Abstract Full Text
free access
JAMA Intern Med. 2017;177(11):1703. doi:10.1001/jamainternmed.2017.6758
Images From Our Readers

Fade Away

Abstract Full Text
JAMA Intern Med. 2017;177(11):1649. doi:10.1001/jamainternmed.2017.5869
JAMA Internal Medicine Masthead

JAMA Internal Medicine

Abstract Full Text
free access
JAMA Intern Med. 2017;177(11):1554. doi:10.1001/jamainternmed.2016.6175
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