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November 2018 - January 1908

Decade

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Issue

November 2018, Vol 178, No. 11, Pages 1437-1572

In This Issue of JAMA Internal Medicine

Highlights

Abstract Full Text
free access
JAMA Intern Med. 2018;178(11):1437-1439. doi:10.1001/jamainternmed.2017.5239
Perspective

Inappropriate Behavior by Patients and Their Families—Call It Out

Abstract Full Text
JAMA Intern Med. 2018;178(11):1441. doi:10.1001/jamainternmed.2018.4348

This essay describes the author’s experiences with inappropriate behavior by patients and their families and proposes techniques to overcome this challenge when treating these patients.

Ambiguity in End-of-Life Care Terminology—What Do We Mean by “Comfort Care?”

Abstract Full Text
JAMA Intern Med. 2018;178(11):1442-1443. doi:10.1001/jamainternmed.2018.4291

This Perspective uses an end-of-life care vignette to illustrate the need to clarify the meaning of the term comfort care.

Memorial Day Reflections—The Invisible Enemy

Abstract Full Text
JAMA Intern Med. 2018;178(11):1444-1445. doi:10.1001/jamainternmed.2018.3109

This Perspective describes a Vietnam veteran with posttraumatic stress disorder including a debilitating startle response refractory to treatment.

Editorial

Treating Obesity—Moving From Recommendation to Implementation

Abstract Full Text
has audio
JAMA Intern Med. 2018;178(11):1447-1449. doi:10.1001/jamainternmed.2018.5259

Notice of Retractions: “First Foods Most: After 18-Hour Fast, People Drawn to Starches First and Vegetables Last,” “Fattening Fasting: Hungry Grocery Shoppers Buy More Calories, Not More Food,” and “Watch What You Eat: Action-Related Television Content Increases Food Intake” by Brian Wansink

Abstract Full Text
free access
JAMA Intern Med. 2018;178(11):1450. doi:10.1001/jamainternmed.2018.5761

These articles by Brian Wansink, PhD, are being retracted.

Original Investigation

Estimated Costs of Pivotal Trials for Novel Therapeutic Agents Approved by the US Food and Drug Administration, 2015-2016

Abstract Full Text
JAMA Intern Med. 2018;178(11):1451-1457. doi:10.1001/jamainternmed.2018.3931

This study estimates the costs of pivotal clinical trials for all new therapeutic agents approved by the US Food and Drug Administration from 2015 to 2016 and examines how key features of the pivotal trials were associated with these costs.

Labeling Changes and Costs for Clinical Trials Performed Under the US Food and Drug Administration Pediatric Exclusivity Extension, 2007 to 2012

Abstract Full Text
JAMA Intern Med. 2018;178(11):1458-1466. doi:10.1001/jamainternmed.2018.3933

This study assesses the benefits of the US Food and Drug Administration’s pediatric exclusivity program in terms of new safety and efficacy data in pediatric populations and the costs to all consumers of extending market exclusivity by 6 months.

Physician Work Environment and Well-Being

Association of Medical Scribes in Primary Care With Physician Workflow and Patient Experience

Abstract Full Text
has active quiz
JAMA Intern Med. 2018;178(11):1467-1472. doi:10.1001/jamainternmed.2018.3956

This crossover study of primary care physicians evaluates whether the use of medical scribes in primary care improves physician productivity and patient satisfaction.

Efficacy of Low-Dose Amitriptyline for Chronic Low Back PainA Randomized Clinical Trial

Abstract Full Text
has active quiz
JAMA Intern Med. 2018;178(11):1474-1481. doi:10.1001/jamainternmed.2018.4222

This randomized clinical trial examines the efficacy of low-dose amitriptyline vs an active comparator in reducing pain, disability, and work absence and hindrance in individuals with chronic low back pain.

Association of Risk for Venous Thromboembolism With Use of Low-Dose Extended- and Continuous-Cycle Combined Oral ContraceptivesA Safety Study Using the Sentinel Distributed Database

Abstract Full Text
JAMA Intern Med. 2018;178(11):1482-1488. doi:10.1001/jamainternmed.2018.4251

This cohort study compares the risk for venous thromboembolism among women who use extended cyclic and continuous combined oral contraceptives (COCs) with that among women who use traditional cyclic COCs, while holding the progestogen type constant.

Association Between Patient Cognitive and Functional Status and Medicare Total Annual Cost of CareImplications for Value-Based Payment

Abstract Full Text
JAMA Intern Med. 2018;178(11):1489-1497. doi:10.1001/jamainternmed.2018.4143

This study analyzes data from the Medicare Current Beneficiary Survey to determine if patient cognitive and functional status and local area health care supply and economic conditions are associated with Medicare total annual cost of care.

Assessment of the Effect of Adjustment for Patient Characteristics on Hospital Readmission RatesImplications for Pay for Performance

Abstract Full Text
JAMA Intern Med. 2018;178(11):1498-1507. doi:10.1001/jamainternmed.2018.4481

This observational study analyzes Medicare claims and US Census data to evaluate differences in hospital readmission rates associated with measurable patient characteristics not used by Medicare to adjust for risk of readmissions in pay-for-performance programs.

Effect of Increased Daily Water Intake in Premenopausal Women With Recurrent Urinary Tract InfectionsA Randomized Clinical Trial

Abstract Full Text
open access
JAMA Intern Med. 2018;178(11):1509-1515. doi:10.1001/jamainternmed.2018.4204

This randomized clinical trial assesses the efficacy of increased daily water intake vs usual fluid intake on the frequency of recurrent cystitis in premenopausal women experiencing recurrent cystitis who drink low volumes of total fluid daily.

Less Is More

Frequency and Associations of Prescription Nonsteroidal Anti-inflammatory Drug Use Among Patients With a Musculoskeletal Disorder and Hypertension, Heart Failure, or Chronic Kidney Disease

Abstract Full Text
JAMA Intern Med. 2018;178(11):1516-1525. doi:10.1001/jamainternmed.2018.4273

This cohort study uses drug benefit claims data in Ontario, Canada, to estimate the frequency of and variation in prescription nonsteroidal anti-inflammatory drug (NSAID) use among high-risk patients with musculoskeletal disorders and hypertension, heart failure, or chronic kidney disease (CKD) and identifies characteristics associated with prescription NSAID use and its potential association with short-term, safety-related outcomes.

Association of Chronic Kidney Disease With Allopurinol Use in Gout Treatment

Abstract Full Text
JAMA Intern Med. 2018;178(11):1526-1533. doi:10.1001/jamainternmed.2018.4463

This cohort study uses data from the UK Health Improvement Network to examine the association of allopurinol use in patients with gout with the risk of developing chronic kidney disease stage 3 or higher.

Invited Commentary

Posttraumatic Stress Disorder in Primary Care Practice

Abstract Full Text
JAMA Intern Med. 2018;178(11):1445-1446. doi:10.1001/jamainternmed.2018.3108

Use of Medical Scribes to Reduce Documentation BurdenAre They Where We Need to Go With Clinical Documentation?

Abstract Full Text
JAMA Intern Med. 2018;178(11):1472-1473. doi:10.1001/jamainternmed.2018.3945

Health Care Reform

Value-Based Payments and Inaccurate Risk Adjustment—Who Is Harmed?

Abstract Full Text
JAMA Intern Med. 2018;178(11):1507-1508. doi:10.1001/jamainternmed.2018.4142

Studying Drug Safety in the Real World

Abstract Full Text
JAMA Intern Med. 2018;178(11):1533-1534. doi:10.1001/jamainternmed.2018.5766

Medicaid Work Requirements—English Poor Law Revisited

Abstract Full Text
JAMA Intern Med. 2018;178(11):1555-1557. doi:10.1001/jamainternmed.2018.4193
Editor's Note

Clinical Trials—We Get What We Pay For

Abstract Full Text
JAMA Intern Med. 2018;178(11):1457. doi:10.1001/jamainternmed.2018.3930

Drinking More Water for Prevention of Recurrent Cystitis

Abstract Full Text
JAMA Intern Med. 2018;178(11):1515. doi:10.1001/jamainternmed.2018.4195
Special Communication

Potential Biases in Machine Learning Algorithms Using Electronic Health Record Data

Abstract Full Text
JAMA Intern Med. 2018;178(11):1544-1547. doi:10.1001/jamainternmed.2018.3763

This Special Communication explores potential biases in machine learning–based clinical decision support tools that use electronic health record (EHR) data and possible solutions to those biases.

Review

Acute Clinical Care for Transgender PatientsA Review

Abstract Full Text
JAMA Intern Med. 2018;178(11):1535-1543. doi:10.1001/jamainternmed.2018.4179

This narrative review discusses the acute clinical care of transgender patients, whether in the hospital, the emergency department, or urgent care.

Research Letter

Education and Reporting of Diagnostic Errors Among Physicians in Internal Medicine Training Programs

Abstract Full Text
JAMA Intern Med. 2018;178(11):1548-1549. doi:10.1001/jamainternmed.2018.4184

This survey study investigates education and reporting of diagnostic errors among resident and attending physicians in internal medicine training programs in Connecticut.

Health Care Policy and Law

Analysis of Work Requirement Exemptions and Medicaid Spending

Abstract Full Text
JAMA Intern Med. 2018;178(11):1549-1552. doi:10.1001/jamainternmed.2018.4194

This study estimates the number of Medicaid enrollees at risk of losing coverage if work requirements are implemented and calculates current Medicaid spending for those enrollees at the national level and among states with approved or pending waivers.

State-Level Population Estimates of Individuals Subject to and Not Meeting Proposed Medicaid Work Requirements

Abstract Full Text
JAMA Intern Med. 2018;178(11):1552-1555. doi:10.1001/jamainternmed.2018.4196

This cross-sectional analysis of 2014 Survey on Income and Program Participation data estimates the potential impact of work requirements on Medicaid eligibility on a state-by-state basis.

Less Is More

Trends in the Use of Knee Arthroscopy in Adults

Abstract Full Text
JAMA Intern Med. 2018;178(11):1557-1558. doi:10.1001/jamainternmed.2018.4175

This study uses the Florida State Ambulatory Surgery and State Inpatient Databases to assess the trends in knee arthroscopy use among patients with osteoarthritis, meniscal tears, and knee pain.

Association Between Antibiotic Prescribing for Respiratory Tract Infections and Patient Satisfaction in Direct-to-Consumer Telemedicine

Abstract Full Text
JAMA Intern Med. 2018;178(11):1558-1560. doi:10.1001/jamainternmed.2018.4318

This study assesses the association between antibiotic prescribing for respiratory tract infections and satisfaction ratings among patients using a direct-to-consumer telemedicine platform.

Less Is More

Factors Associated With Long-term Benzodiazepine Use Among Older Adults

Abstract Full Text
JAMA Intern Med. 2018;178(11):1560-1562. doi:10.1001/jamainternmed.2018.2413

This cohort study evaluates factors associated with the transition to long-term benzodiazepine use among older adults newly prescribed this drug by a nonpsychiatric clinician.

Comment & Response

Meeting the Criteria of Medication Therapy Management

Abstract Full Text
JAMA Intern Med. 2018;178(11):1562-1563. doi:10.1001/jamainternmed.2018.5789

Meeting the Criteria of Medication Therapy Management—Reply

Abstract Full Text
JAMA Intern Med. 2018;178(11):1563. doi:10.1001/jamainternmed.2018.5792

Limited Focus in Evaluation of Vaccine Cost-effectiveness

Abstract Full Text
JAMA Intern Med. 2018;178(11):1563-1564. doi:10.1001/jamainternmed.2018.5801

Limited Focus in Evaluation of Vaccine Cost-effectiveness—Reply

Abstract Full Text
JAMA Intern Med. 2018;178(11):1564. doi:10.1001/jamainternmed.2018.5804

Re-examining the Association Between “4/20” and Fatal Crashes—Doobie-ous Data?

Abstract Full Text
JAMA Intern Med. 2018;178(11):1565. doi:10.1001/jamainternmed.2018.5856

Further Lessons in Pneumocystis Pneumonia Prophylaxis

Abstract Full Text
JAMA Intern Med. 2018;178(11):1565-1566. doi:10.1001/jamainternmed.2018.5930

Further Lessons in Pneumocystis Pneumonia Prophylaxis—Reply

Abstract Full Text
JAMA Intern Med. 2018;178(11):1566-1567. doi:10.1001/jamainternmed.2018.5933

Mineralocorticoid Receptor Antagonism Treatment for All Patients With ST-Segment Myocardial Infarction?

Abstract Full Text
JAMA Intern Med. 2018;178(11):1567. doi:10.1001/jamainternmed.2018.5950

Mineralocorticoid Receptor Antagonism Treatment for All Patients With ST-Segment Myocardial Infarction?—Reply

Abstract Full Text
JAMA Intern Med. 2018;178(11):1567-1568. doi:10.1001/jamainternmed.2018.5964
Correction

Caution Advised for Readers of Letters Related to Retracted Article

Abstract Full Text
free access
JAMA Intern Med. 2018;178(11):1568. doi:10.1001/jamainternmed.2018.6048

Caution Advised for Readers of Comments Related to Retracted Article

Abstract Full Text
free access
JAMA Intern Med. 2018;178(11):1568. doi:10.1001/jamainternmed.2018.6238

Caution Advised for Readers of Comments Related to Retracted Article

Abstract Full Text
free access
JAMA Intern Med. 2018;178(11):1568. doi:10.1001/jamainternmed.2018.6240

Numeric Errors in Table 1

Abstract Full Text
free access
JAMA Intern Med. 2018;178(11):1568. doi:10.1001/jamainternmed.2018.6396
Images From Our Readers

Guggenheim Museum, New York City

Abstract Full Text
JAMA Intern Med. 2018;178(11):1497. doi:10.1001/jamainternmed.2018.5415
JAMA Internal Medicine Patient Page

I Have Insomnia—What Should I Do?

Abstract Full Text
free access
JAMA Intern Med. 2018;178(11):1572. doi:10.1001/jamainternmed.2018.2626

This Patient Page provides information on insomnia—how to recognize it and how it is best treated.

JAMA Internal Medicine Masthead

JAMA Internal Medicine

Abstract Full Text
free access
JAMA Intern Med. 2018;178(11):1440. doi:10.1001/jamainternmed.2017.5240
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