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August 2019 - January 1908

Decade

Year

Issue

April 2018, Vol 178, No. 4, Pages 445-589

In This Issue of JAMA Internal Medicine

Highlights

Abstract Full Text
free access
JAMA Intern Med. 2018;178(4):445-447. doi:10.1001/jamainternmed.2017.5204
Editorial

The Trade-offs When Focusing on the Mortality Benefit

Abstract Full Text
JAMA Intern Med. 2018;178(4):455. doi:10.1001/jamainternmed.2018.0067

JAMA Internal Medicine—The Year in Review, 2017

Abstract Full Text
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JAMA Intern Med. 2018;178(4):456-457. doi:10.1001/jamainternmed.2017.7909
Original Investigation

Breast Biopsy Intensity and Findings Following Breast Cancer Screening in Women With and Without a Personal History of Breast Cancer

Abstract Full Text
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JAMA Intern Med. 2018;178(4):458-468. doi:10.1001/jamainternmed.2017.8549

This population-based cohort study uses cancer registry data to examine the biopsy rates and yield in the 90 days following screening (mammography vs MRI with or without mammography) among women with and without a personal history of breast cancer.

Association of Cigarette, Cigar, and Pipe Use With Mortality Risk in the US Population

Abstract Full Text
free access has active quiz
JAMA Intern Med. 2018;178(4):469-476. doi:10.1001/jamainternmed.2017.8625

This longitudinal, population-based cohort study examines the mortality risks associated with use of cigar, pipes, and cigarettes.

Unrecognized Cardiovascular Emergencies Among Medicare Patients

Abstract Full Text
free access has active quiz
JAMA Intern Med. 2018;178(4):477-484. doi:10.1001/jamainternmed.2017.8628

This cohort study estimates the proportions of emergency department visits attributable to symptoms of imminent ruptured abdominal aortic aneurysm, acute myocardial infarction, stroke, aortic dissection, and subarachnoid hemorrhage that end in discharge without diagnosis.

Daily vs Intermittent Antituberculosis Therapy for Pulmonary Tuberculosis in Patients With HIV: A Randomized Clinical Trial

Abstract Full Text
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JAMA Intern Med. 2018;178(4):485-493. doi:10.1001/jamainternmed.2018.0141

This randomized clinical trial tests the safety and efficacy of daily vs intermittent antituberculosis therapy in HIV-positive patients.

Family History and Breast Cancer Risk Among Older Women in the Breast Cancer Surveillance Consortium Cohort

Abstract Full Text
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JAMA Intern Med. 2018;178(4):494-501. doi:10.1001/jamainternmed.2017.8642

This cohort study investigates whether first-degree family history of breast cancer is associated with increased risk of breast cancer among older women.

Association of Vegetation Size With Embolic Risk in Patients With Infective Endocarditis: A Systematic Review and Meta-analysis

Abstract Full Text
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JAMA Intern Med. 2018;178(4):502-510. doi:10.1001/jamainternmed.2017.8653

This systematic review and meta-analysis evaluates the association of vegetation size greater than 10 mm with emobolic events in patients with infective endocarditis.

Effect of a Collaborative Care Intervention vs Usual Care on Health Status of Patients With Chronic Heart Failure: The CASA Randomized Clinical Trial

Abstract Full Text
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JAMA Intern Med. 2018;178(4):511-519. doi:10.1001/jamainternmed.2017.8667

This randomized clinical trial examines whether a symptom and psychosocial collaborative care intervention vs usual care improves heart failure–specific health status, depression, and symptom burden in patients with heart failure.

Effectiveness of an Intervention Supporting Shared Decision Making for Destination Therapy Left Ventricular Assist Device: The DECIDE-LVAD Randomized Clinical Trial

Abstract Full Text
open access
JAMA Intern Med. 2018;178(4):520-529. doi:10.1001/jamainternmed.2017.8713

This randomized clinical trial examines the effectiveness of a shared decision support intervention for patients considering destination therapy left ventricular assist device placement.

Effect of Protein Intake on Lean Body Mass in Functionally Limited Older Men: A Randomized Clinical Trial

Abstract Full Text
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JAMA Intern Med. 2018;178(4):530-541. doi:10.1001/jamainternmed.2018.0008

This randomized clinical trial investigates whether greater than the recommended dietary allowance of protein is needed to maintain lean body mass in older adults.

Effectiveness of a Peer Navigation Intervention to Sustain Viral Suppression Among HIV-Positive Men and Transgender Women Released From Jail: The LINK LA Randomized Clinical Trial

Abstract Full Text
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JAMA Intern Med. 2018;178(4):542-553. doi:10.1001/jamainternmed.2018.0150

This randomized clinical trial tests the effect of the manualized LINK LA peer navigation intervention vs standard transitional case management on HIV viral suppression among released inmates with HIV.

Invited Commentary

An HIV Behavioral Intervention Gets It Right—and Shows We Must Do Even Better

Abstract Full Text
JAMA Intern Med. 2018;178(4):553-555. doi:10.1001/jamainternmed.2018.0096
Evidence to Practice

Cognitive and Mind-Body Therapies for Chronic Low Back Pain and Neck Pain: Effectiveness and Value

Abstract Full Text
JAMA Intern Med. 2018;178(4):556-557. doi:10.1001/jamainternmed.2018.0113

This article discusses the Institute for Clinical and Economic Review’s study of acupuncture, cognitive behavioral therapy, mindfulness-based stress reduction, yoga, and tai chi to treat chronic low back pain.

Teachable Moment

Less Is More

Management of Patients With Febrile Neutropenia: A Teachable Moment

Abstract Full Text
JAMA Intern Med. 2018;178(4):558-559. doi:10.1001/jamainternmed.2017.8386

This Teachable Moment uses the case of a woman in her 30s undergoing chemotherapy for stage 2A breast cancer who was hospitalized for febrile neutropenia to illustrate the need to avoid overtreatment for low-risk patients with this common oncological complication.

Research Letter

Association of Baseline Statin Use Among Older Adults Without Clinical Cardiovascular Disease in the SPRINT Trial

Abstract Full Text
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JAMA Intern Med. 2018;178(4):560-561. doi:10.1001/jamainternmed.2017.7844

This secondary analysis of the Systolic Blood Pressure Intervention trial examines whether a treatment program aimed at reducing systolic blood pressure to a lower goal than currently recommended would reduce cardiovascular disease risk among patients without diabetes.

Generic Substitution Rates of Oral Contraceptives and Associated Out-of-Pocket Cost Savings Between January 2010 and December 2014

Abstract Full Text
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JAMA Intern Med. 2018;178(4):561-563. doi:10.1001/jamainternmed.2017.7849

This analysis of survey data describes generic oral contraceptive use and out-of-pocket cost savings by switching from brand to generic oral contraceptives in a nationally representative sample.

Assessment of Linked Associations in Predictors of Life Expectancy Inequality

Abstract Full Text
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JAMA Intern Med. 2018;178(4):563-564. doi:10.1001/jamainternmed.2017.7893

This data analysis compares the rise of income inequality, as well as racial inequality, over a same time frame as the rise in life expectancy inequality.

Health Care Reform

Employment Status and Health Characteristics of Adults With Expanded Medicaid Coverage in Michigan

Abstract Full Text
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JAMA Intern Med. 2018;178(4):564-567. doi:10.1001/jamainternmed.2017.7055

This survey study examines the demographic and health characteristics associated with the employment status of current Medicaid expansion enrollees in Michigan.

Medicare Spending and Potential Savings on Brand-Name Drugs With Available Generic Substitutes Excluded by 2 Large Pharmacy Benefit Managers, 2012 Through 2015

Abstract Full Text
free access
JAMA Intern Med. 2018;178(4):567-569. doi:10.1001/jamainternmed.2017.8016

This study uses Medicare Part D drug utilization and spending data to estimate potential Part D program and beneficiary savings on brand-name medications excluded by pharmacy benefit managers for which generic substitutes are available.

The April 20 Cannabis Celebration and Fatal Traffic Crashes in the United States

Abstract Full Text
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JAMA Intern Med. 2018;178(4):569-572. doi:10.1001/jamainternmed.2017.8298

This data analysis examines the association between the April 20 cannabis celebrations in the United States and a population-level increase in the risk of fatal traffic crash involvement.

Less Is More

Association of Standardization of Continuous Renal Replacement Therapy and High-Value Care: An Evidence-Based Approach

Abstract Full Text
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JAMA Intern Med. 2018;178(4):572-573. doi:10.1001/jamainternmed.2017.8732

This cohort study assesses utilization patterns of continuous renal replacement therapy and attempts to establish evidence-based guidelines to standardize the process flow and to promote meaningful use.

Comment & Response

Evidence-Based Rationale for Use of Inferior Vena Cava Filters

Abstract Full Text
JAMA Intern Med. 2018;178(4):573-574. doi:10.1001/jamainternmed.2018.0058

Questionable Conclusions Regarding Blood Pressure End Points

Abstract Full Text
JAMA Intern Med. 2018;178(4):574-575. doi:10.1001/jamainternmed.2018.0026

Evidence-Based Rationale for Use of Inferior Vena Cava Filters—Reply

Abstract Full Text
JAMA Intern Med. 2018;178(4):574. doi:10.1001/jamainternmed.2018.0061

Questionable Conclusions Regarding Blood Pressure End Points—Reply

Abstract Full Text
JAMA Intern Med. 2018;178(4):575-576. doi:10.1001/jamainternmed.2018.0029

Questionable Conclusions Regarding Blood Pressure End Points

Abstract Full Text
JAMA Intern Med. 2018;178(4):575. doi:10.1001/jamainternmed.2018.0340

Physician Burnout—Overdiagnosis and Unproven Interventions

Abstract Full Text
JAMA Intern Med. 2018;178(4):576-577. doi:10.1001/jamainternmed.2018.0132

Physician Burnout—Overdiagnosis and Unproven Interventions—Reply

Abstract Full Text
JAMA Intern Med. 2018;178(4):577-578. doi:10.1001/jamainternmed.2018.0163

What Patients Expect and Deserve—Reply

Abstract Full Text
JAMA Intern Med. 2018;178(4):578-579. doi:10.1001/jamainternmed.2018.0135

What Patients Expect and Deserve

Abstract Full Text
JAMA Intern Med. 2018;178(4):578. doi:10.1001/jamainternmed.2018.0138

Concerns Regarding Resource Use and Outcomes in Subsets of Clinicians

Abstract Full Text
JAMA Intern Med. 2018;178(4):579-580. doi:10.1001/jamainternmed.2018.0197

Concerns Regarding Resource Use and Outcomes in Subsets of Clinicians

Abstract Full Text
JAMA Intern Med. 2018;178(4):580. doi:10.1001/jamainternmed.2018.0206

Concerns Regarding Resource Use and Outcomes in Subsets of Clinicians

Abstract Full Text
JAMA Intern Med. 2018;178(4):580. doi:10.1001/jamainternmed.2018.0209

Concerns Regarding Resource Use and Outcomes in Subsets of Clinicians—Reply

Abstract Full Text
JAMA Intern Med. 2018;178(4):581. doi:10.1001/jamainternmed.2018.0184

Incorrect Conclusions of a Secondary Analysis

Abstract Full Text
JAMA Intern Med. 2018;178(4):581-582. doi:10.1001/jamainternmed.2018.0212

Incorrect Conclusions of a Secondary Analysis—Reply

Abstract Full Text
JAMA Intern Med. 2018;178(4):582. doi:10.1001/jamainternmed.2018.0187

Incorrect Conclusions of a Secondary Analysis—Reply

Abstract Full Text
JAMA Intern Med. 2018;178(4):582-583. doi:10.1001/jamainternmed.2018.0203

Uses of H.P. Acthar Gel in the Clinical Setting

Abstract Full Text
JAMA Intern Med. 2018;178(4):583. doi:10.1001/jamainternmed.2017.8542

Uses of H.P. Acthar Gel in the Clinical Setting—Reply

Abstract Full Text
JAMA Intern Med. 2018;178(4):583-584. doi:10.1001/jamainternmed.2017.8545

Lower Cancer Incidence—Warfarin Effect or Immortal Time Bias?

Abstract Full Text
JAMA Intern Med. 2018;178(4):584-585. doi:10.1001/jamainternmed.2018.0367

Lower Cancer Incidence—Warfarin Effect or Immortal Time Bias?—Reply

Abstract Full Text
JAMA Intern Med. 2018;178(4):585-586. doi:10.1001/jamainternmed.2018.0364

Lower Cancer Incidence—Warfarin Effect or Immortal Time Bias?

Abstract Full Text
JAMA Intern Med. 2018;178(4):585. doi:10.1001/jamainternmed.2018.0370

Further Questions Regarding Electrocardiogram Prior to Liver Transplant

Abstract Full Text
JAMA Intern Med. 2018;178(4):586. doi:10.1001/jamainternmed.2018.0569

Further Questions Regarding Electrocardiogram Prior to Liver Transplant—Reply

Abstract Full Text
JAMA Intern Med. 2018;178(4):586-587. doi:10.1001/jamainternmed.2018.0572

Assessing Pharmaceutical Research and Development Costs

Abstract Full Text
JAMA Intern Med. 2018;178(4):587. doi:10.1001/jamainternmed.2017.8703

Assessing Pharmaceutical Research and Development Costs

Abstract Full Text
JAMA Intern Med. 2018;178(4):587-588. doi:10.1001/jamainternmed.2017.8706

Assessing Pharmaceutical Research and Development Costs—Reply

Abstract Full Text
JAMA Intern Med. 2018;178(4):588-589. doi:10.1001/jamainternmed.2017.8737

Methods Used to Assess Pharmaceutical Research and Development Costs

Abstract Full Text
JAMA Intern Med. 2018;178(4):589. doi:10.1001/jamainternmed.2018.0110
Images From Our Readers

Golden Hour, Great Lawn, Central Park

Abstract Full Text
JAMA Intern Med. 2018;178(4):457. doi:10.1001/jamainternmed.2018.0881
Peer Reviewers List

JAMA Internal Medicine Peer Reviewers in 2017

Abstract Full Text
free access online only
JAMA Intern Med. 2018;178(4):e180702. doi:10.1001/jamainternmed.2018.0702
JAMA Internal Medicine Masthead

JAMA Internal Medicine

Abstract Full Text
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JAMA Intern Med. 2018;178(4):448. doi:10.1001/jamainternmed.2017.5205
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