This Viewpoint discusses the US shortage of normal saline after Hurricane Maria crippled pharmaceutical manufacturing in Puerto Rico and how to prevent similar shortages in the future.
This article explores the experience of a physician advocate in communicating about end-of-life care and physician-assisted suicide with a patient with stage 4 lung cancer.
This repeated cross-sectional study examines the association between the restrictiveness of state alcohol policies with the likelihood of alcohol involvement among adults dying in motor vehicle crashes in the United States.
This large cohort study quantifies the association between metformin use and hospitalization with acidosis across the range of estimated glomerular filtration rate (eGFR), accounting for change in eGFR stage over time.
This systematic review and meta-analysis of 10 randomized clinical trials explores the role of treatment with aldosterone antagonists in patients with ST-segment elevation myocardial infarction (STEMI) without heart failure or left ventricular ejection fraction greater than 40%.
This analysis of 2 cohort studies examines the accuracy of proxies’ prognostic estimates for nursing home residents with advanced dementia and the association of their estimates with use of burdensome interventions.
This randomized clinical trial evaluates the effect of a communication-priming intervention designed to increase patient-reported goals-of-care discussions between patients with serious illness and clinicians vs usual care.
This population-based cohort study examines claims data in a large US insurer to assess changes in prescribing and adherence to platelet adenosine diphosphate P2Y12 receptor inhibitors by patients after percutaneous coronary intervention and after introduction of newer, more expensive agents.
This randomized clinical trial investigates the effect of increased attending physician supervision on an inpatient resident general medical service on patient safety and educational outcomes.
This cluster randomized clinical trial tests whether an advance care planning video (vs usual care) has an effect on documented advance directives, level of care preferences, goals-of-care discussions, and burdensome treatments among nursing home residents with advanced dementia.
This evidence review and implementation guide reviews the evidence and formulates a process for implementing procedures to avoid unnecessary electrocardiographic monitoring.
This review summarizes the National Academies of Sciences, Engineering, and Medicine’s report on the public health consequences of e-cigarette use.
This case report presents the elecrocardiographic findings of a man in his 50s with dizziness, shortness of breath, and tachycardia in whom electrical cardioversion was unsuccessful until the sixth attempt.
A woman in her 20s presented with a medical history of multiple, unwitnessed, nonexertional syncopal events in the previous 24 hours that were preceded by palpitations, and associated with loss of consciousness lasting 30 minutes. What is your diagnosis?
This study examines the proportion of all severe hypoglycemic events that are captured by surveillance based on health care utilization alone among pharmacologically treated patients with diabetes.
This study examines trends in advanced practice clinician employment across different physician practices in the United States.
This study examines the extent to which trials registered in ClinicalTrials.gov by individual sponsors for the same drug and condition were available publicly in ClinicalTrials.gov and/or PubMed.
This study evaluates the duration of antibiotic therapy prescribed for US adults with sinusitis.
This cohort study examines the clinical usefulness and cost of blood cultures and imaging in patients with presumed cellulitis.
This data review investigates the characteristics and conflicts of interest of public speakers at Anesthetic and Analgesic Drug Products Advisory Committee meetings.
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