This Viewpoint discusses the potential overstatement of findings in 2 studies that used predictive risk scores to draw conclusions about precision preventive medicine and suggests that improvements to predictive methods are necessary before being more widely applied.
This Viewpoint discusses how physician burnout, depression, and suicide can arise from guilt feelings that physicians have sublimated into their work.
This Perspective describes the physician’s role in caring for survivors of domestic abuse.
This article discusses the high frequency of mass shootings in the United States and outlines potential legislative solutions.
This cohort study uses Medicare claims data to investigate the association of patient outcomes and Medicare costs of discharge to home with home health care vs discharge to a skilled nursing facility.
This study analyzes the prospective registration policies of specialty journals that publish randomized clinical trials of drugs, biologics, and medical devices not regulated by the US Food and Drug Administration.
This nationwide cohort study examines the risk of hepatocellular carcinoma in Taiwanese patients with chronic hepatitis B who are receiving daily aspirin therapy.
This study analyzes the original and updated clinical trials that led to FDA-approved drug indications in oncology from 2006 to 2017 to assess reduction in clinical trial duration derived from using surrogate end points of response rate or progression-free survival rather than overall survival as the basis for cancer drug approval.
This study assesses the utilization and costs of a multipronged quality improvement initiative to reduce low-value preoperative utilization for patients undergoing cataract surgery at 2 safety-net health systems in California.
This cohort study investigates the performance of screening mammography plus screening ultrasonography compared with screening mammography alone among women at low, intermediate, and high risk for breast cancer.
This cohort study uses data from the Health and Retirement Study to determine whether middle-aged individuals who develop functional impairment are at increased risk for hospitalization, nursing home admission, and death.
This secondary analysis of a cohort study examines communications between clinicians and surrogate decision makers on what the surrogates believe reflect the goals of care of critically ill patients.
This study analyzes data from the 2015 National Emergency Department Sample for hospital-based emergency department discharges, transfers, and admissions for patients presenting with pneumonia, chronic obstructive pulmonary disease, and asthma.
This Editor’s Note advocates for greater implementation of the shared decision-making visit before lung cancer screening, citing the high percentage of patients who choose not to undergo screening after discussion of benefits vs harms.
This Special Communication summarizes the limited published evidence to support off-label gabapentinoid uses, describes clinical cases in which off-label use is problematic, and notes how review articles and guidelines tend to overstate gabapentinoid effectiveness.
This nationwide survey of US primary care internists and medical specialists evaluates physicians’ attitudes about the US Food and Drug Administration’s drug approval standards and off-label drug marketing.
This study examines national survey results from hospital pharmacy managers to investigate current drug allocation and rationing practices of US hospitals during drug shortages.
This assessment of common primary care measures from 10 Veterans Affairs clinics from 2014 compares outcomes in patients of resident physicians with patients of attending physicians.
This study uses wholesale medication acquisition costs and Medicare claims data to assess how prices of existing tumor necrosis factor inhibitors changed in response to the market entry of new tumor necrosis factor inhibitors.
This study analyzes Medicare data from 2015 and 2016 to estimate the percentage of Medicare enrollees who underwent low-dose computed tomographic screening for lung cancer during this period and had participated in a shared decision-making visit to discuss the benefits and risks of the procedure before screening.
This cohort study of FDA- and drug sponsor–written communications evaluates the communication of nonefficacy benefits of new drugs approved on the basis of noninferiority trials alone.
This survey study evaluates the frequency of sales of over-the-counter insulin at US pharmacies.
This case report presents the electrocardiographic findings of a man who noted a low pulse when checking his blood pressure and had no symptoms of bradycardia, such as dizziness, syncope, or fatigue.
This case report presents the electrocardiographic findings of a man in his 70s with Wellens syndrome.
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