This Viewpoint describes current guidance for surrogate decision making for incarcerated patients who lack decisional capacity and gives recommendations on how to improve that guidance.
This essay highlights the importance of the Beers Criteria and the challenges associated with prescribing medications to older patients.
This article recalls the author’s mother’s death and the comfort a shared ritual provided the family while she died and suggests that a ritual, spiritual or otherwise, may ease the emotionally difficult experience of a loved one’s death.
This cost-effectiveness analysis estimates the quality of life and economic outcomes associated with 12 cervical cancer screening strategies among women aged 21 to 65 years.
This cohort study evaluates the performance of the p16/Ki-67 dual stain and human papillomavirus (HPV) 16/18 genotyping for the triage of women with HPV infection.
This cross-sectional study of 3157 US Chinese older adults examines the associations of child maltreatment and intimate partner violence with elder abuse.
This secondary analysis of a randomized clinical trial compares the association of nonfasting vs fasting lipid levels with coronary and vascular outcomes and assesses differences in calculated risk among participants undergoing both measurements.
This study assesses the end points used to verify benefit in confirmatory trials of cancer drugs approved via the FDA’s accelerated approval pathway and updates the status of indications for which confirmatory trials were ongoing during the initial analysis of accelerated approval.
This study examines the US Food and Drug Administration’s use of response rates as surrogate end points for approval of cancer drugs.
This population-based study examines the changes in economic and clinical outcomes after institution of the Comprehensive Care for Joint Replacement bundled payment program by the Centers for Medicare & Medicaid Services.
This study examines the implications of the Initiating Dialysis Early and Late randomized clinical trial findings for the dialysis initiation decision and other interventions for patients who need long-term dialysis.
This modeling study uses international, multi-ethnic derivation and validation cohorts of patients with biopsy-proven IgA nephropathy to evaluate a risk-prediction tool for 50% decline in kidney function or end-stage renal disease.
This cohort study uses US Medicare claims to estimate the rate of different-day upper and lower endoscopic procedures in 3 types of outpatient settings and investigate the factors associated with the performance of these procedures on different days.
This Special Communication summarizes effective interventions aimed at promoting sleep and reducing inappropriate sedative-hypnotic initiation among inpatients and proposes an implementation strategy to guide quality improvement teams.
This study assesses primary care spending as a proportion of total spending among Medicare fee-for-service beneficiaries by using narrow and broad definitions of primary care practitioners and services.
This study uses state-based data linkage across prescription drug, hospital, and criminal justice records to identify populations at an elevated risk of fatal opioid overdose.
This study examines how often medicines regulators in Australia, Canada, the United Kingdom, and the United States were concordant in their decisions to issue safety advisories on approved prescription medicines.
This survey study of statewide California hospitals evaluates the prevalence and institutional characteristics of hospitals and health systems that have either implemented or opted out of the state’s End of Life Option Act.
This cohort study examines the incidence of mortality 1 year after the start of hemodialysis in patients 65 years and older.
This time series study evaluates whether increasing the threshold for identifying uropathogens is associated with a decrease in antimicrobial treatment.
This cross-sectional survey study examines the factors associated with satisfaction at work in academic health care centers.
This case report describes changes in the electrocardiogram of a patient with anaphylaxis after an overdose of epinephrine.
This case report presents the electrocardiographic findings of a man in his 70s with a history of orthotopic heart transplant presenting with dizziness.
This Patient Page describes the symptoms and recommended treatment options for patients with opioid use dissorder.
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