This noninferiority randomized clinical trial assesses the renal safety of prophylactic prehydration vs no prehydration prior to administration of iodine-based contrast media in patients with stage 3 chronic kidney disease.
This cohort study compares 30-day mortality among adult patients hospitalized for pneumonia receiving empirical anti–methicillin-resistant Staphylococcus aureus (MRSA) therapy vs standard empirical antibiotic regimens.
This cohort study compares cardiovascular and safety outcomes of chlorthalidone and hydrochlorothiazide as first-line therapies for adults with hypertension.
This ecenomic evaluation study analyzes the share of overall net income and charity care for hospitals based on overall net income in 2017.
This cross-sectional analysis examines the prevalence of unregulated resale of insulin, albuterol, and epipenephrin online in the United States.
This Patient Page describes the risks, benefits, and regulation of medical cannabis.
This Perspective highlights the issue of physician suicide and how to potentially address it.
This cross-sectional study uses rates of vitamin D and triiodothyronine level testing to examine the association of recent policies, recommendations, and systems of care with changes in the use of low-value services at regional and national levels in Canada and the United States.
This narrative review discusses biological and social factors associated with sex- and gender-based differences in health, health care, and disease to provide a guide for clinicians practicing precision medicine.
This systematic review and meta-analysis of randomized clinical trials assesses the effectiveness and safety of aspirin for venous thromboembolism prophylaxis after total hip replacement and total knee replacement.
This cohort study assesses whether consuming processed meat, unprocessed red meat, poultry, or fish is associated with incident cardiovascular disease and all-cause mortality among US adults participating in 6 long-term cohort studies.
This study characterizes the costs of recommended initial HIV antiretroviral therapy regimens in the United States from 2012 to 2018 and the magnitude of cost changes over time.
This economic evaluation estimates insulin savings that would result if Medicare Part D used US Department of Veterans Affairs–negotiated prices and the Veterans Affairs formulary for patients with diabetes.
This case report describes an older patient who presented with electrocardiographic ST-segment elevation that was discovered to have an unusual cause.
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