This multicenter nonrandomized clinical trial with crossover design study determines the feasibility and results of implementing 2 core stewardship intervention strategies, preauthorization and postprescription audit and review, in community hospitals.
This randomized clinical trial evaluates the efficacy, feasibility, and acceptability of a parent-targeted intervention for parent-adolescent communication about sexual health and alcohol use.
This randomized clinical trial compares antibiotic use among adult patients in Pakistan receiving bismuth subsalicylate vs placebo for diarrhea.
This pragmatic randomized clinical trial evaluates the long-term effectiveness of a community-based physical activity coaching intervention on acute care and survival in patients with chronic obstructive pulmonary disease.
This cross-sectional study investigates the number of pediatric cannabis exposure cases reported to a regional poison control center before vs after medical marijuana legalization in Massachusetts.
This population-based cohort study examines the sex-based variations in burdensome interventions (care transitions, invasive procedures, and use of physical restraints) and antibiotic therapy at the very end of life among nursing home residents with advanced dementia in Ontario, Canada.
This cross-sectional study of pediatric neurology patients residing in rural areas compares rates of hospital encounters for patients who had outpatient telemedicine consultations vs those who visited neurology clinics in person.
This secondary analysis of a cohort study examines agreement between partial pressure of carbon dioxide, arterial (Paco2) and end-tidal carbon dioxide (EtCO2) and associated factors in children with traumatic brain injury (TBI).
This survey study determines which electronic health record (EHR) design and use factors are associated with clinician stress and burnout and identifies other sources that contribute to this problem.
This cross-sectional study examines firearm ownership and storage practices among US military personnel who have experienced thoughts of suicide.
This survey study assesses how often patients choose not to disclose to their clinicians imminent threats to their well-being (depression, suicidality, abuse, and sexual assault) and examines patient reasons for nondisclosure.
This comparative effectiveness research study assesses whether using present on admission codes and single, rather than grouped, diagnostic codes can enhance Centers for Medicare & Medicaid (CMS) models to predict payment for hospitalization for acute myocardial infarction, heart failure, and pneumonia.
This quality improvement study uses a novel data collection and visualization tool to audit hand hygiene adherence before and after training among health care workers in low-resource settings at 2 hospitals in Nigeria.
This cohort study evaluates the ideal timing of adjuvant therapy for patients with stage I to II resected pancreatic cancer.
This cross-sectional analysis examines the associations among clinical practice group performance on quality measures, including process measures, disease control measures, and utilization-based outcomes, among adults treated for diabetes.
This cross-sectional study evaluates use of nonradioactive multispectral optoacoustic tomographic vs lymphoscintigraphic imaging for biopsy of sentinel lymph nodes in patients with melanoma.
This case series uses data from the US Food and Drug Administration’s Adverse Event Reporting System to assess the postmarketing safety profile of sipuleucel-T.
This cross-sectional study examines temporal shifts in age distribution of obesity-associated cancers and non–obesity-associated cancers across race/ethnicity- and sex-specific strata.
This cross-sectional study measures patient use of smartphone applications to download health record data.
This survey study compares use of prophylactic cranial irradiation in patients with extensive-stage small cell lung cancer before and after the publication of a phase 3 trial that demonstrated no overall survival benefit for this therapy.
This study examines the association of extreme heat events in 3 northeastern US cities with hospital admission and mortality among patients with end-stage renal disease (ESRD).
This cohort study investigates the longitudinal association between depressive symptoms, cognition, and cortical amyloid in unimpaired community-dwelling older adults in the Harvard Aging Brain Study.
This cohort study evaluates and compares patterns of the use of medical aid in dying in Oregon and Washington State.
This cross-sectional study investigates temporal trends in the use and costs of cardiac imaging for patients with heart failure in Canada and examines the association between the institution of an accreditation program and the use of echocardiography.
This diagnostic study evaluates computer vision methods to assist pathologists in diagnosing breast biopsy samples, from benign to invasive cancer.
This systematic review and meta-analysis determines the association of BRAF and MEK inhibitor treatment with cardiovascular adverse events in patients with melanoma compared with BRAF inhibitor monotherapy.
This cohort study compares outcomes associated with cortical-sparing adrenalectomy vs total adrenalectomy for patients with bilateral pheochromocytomas.
This cohort study of healthy individuals in England who underwent repeated bone density scans from ages 10 to 25 years describes the association between the timing of puberty and bone mineral density.
This cohort study uses the US Centers for Medicare & Medicaid Services Provider Payments database to identify whether sex-based discrepancies exist in clinical practice, reimbursement payments, and geographic distributions in the urological specialty.
This is a trial protocol for the Arthroscopic Rotator Cuff trial, an ongoing randomized clinical trial to examine the effectiveness of operative vs nonoperative treatment for atraumatic rotator cuff tears, with patient-reported Shoulder Pain and Disability Index score as the primary outcome.
This randomized clinical trial examines the efficacy of a technology-enhanced community health nursing intervention for improving pelvic inflammatory disease (PID) self-management and longitudinal prevalence of Neisseria gonorrhoeae and Chlamydia trachomatis.
This randomized clinical trial compares the effectiveness of telephone-delivered collaborative goal setting and behavioral activation vs enhanced usual care for depression symptoms among US veterans with uncontrolled diabetes.
This quality improvement study evaluates time to reporting electronic clinical quality measures for US primary care practices.
This systematic review and meta-analysis investigates whether magnetic resonance imaging combined with targeted biopsy is associated with improved detection of clinically significant prostate cancer compared with transrectal ultrasonography–guided systematic prostate biopsy alone.
This cross-sectional study examines characteristics of safety-net hospitals as classified under 3 common definitions based on Medicare Disproportionate Share Hospital payments, Medicaid and uninsured caseload, and uncompensated care costs.
This cross-sectional study identifies a set of emergency care–sensitive conditions to provide benchmark US national estimates of acute care utilization for these conditions.
This multicenter cohort study of adults who have survived hospitalization for sepsis assesses whether abnormalities in the host immune response during hospitalization for sepsis persist after discharge.
This diagnostic study evaluates whether a machine learning model, the Pulmonary Embolism Result Forecast Model (PERFORM), can compute a patient-specific risk score for pulmonary embolism as clinical decision support for computed tomography.
This nationwide cohort study in Taiwan evaluates whether attention-deficit/hyperactivity disorder (ADHD) is associated with higher risk of mortality from all causes, suicide, unintentional injury, homicide, and natural causes.
This cohort study evaluates the association of prophylactic bilateral salpingo-oophorectomy with bone mineral density loss among women with a BRCA mutation.
This cross-sectional, population-based study provides current estimates of the prevalence, severity, distribution, and clinical characteristics of sesame allergy in US adults and children.
This randomized clinical trial investigates the efficacy and safety of adding ramucirumab to first-line therapy with S-1 and oxaliplatin among East Asian adults with advanced gastric cancer.
This cohort study investigates the rate of ophthalmology referral, the prevalence of visual sequelae, and the association between tumor characteristics and ophthalmologic diagnoses in pediatric patients with primary brain tumors.
This cohort study evaluates whether the 2016 release of the Centers for Disease Control and Prevention (CDC) guidelines for opioid prescribing was associated with changes in the rates of opioid and benzodiazepine coprescription among commercially insured patients and US Medicare Advantage beneficiaries.
This case series study identifies surgical and operative factors selected by a machine learning algorithm to classify individuals by level of expertise in a virtual reality surgical procedure.
This cross-sectional study assesses the utility of deep learning for identifying environments and objects associated with smoking.
This quality improvement study characterizes the content of cardiac catheterization peer reviews in the US Department of Veterans Affairs (VA) Clinical Assessment, Reporting, and Tracking (CART) program.
This systematic review and meta-analysis estimates the global incidence of frailty and prefrailty among community-dwelling adults 60 years or older.
This population-based cohort study assesses the association between primary care continuity from pediatric to adult health care services during adolescence and outcomes in young adulthood for patients with severe mental illness in Ontario, Canada.
This survey study examines how gender disparities are associated with attrition from the workforce and how family considerations are associated with decisions about how much to work.
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