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March 2019, Vol 2, No. 3

PEDIATRICS

Prevalence of Bacteremia and Bacterial Meningitis in Febrile Neonates and Infants in the Second Month of Life: A Systematic Review and Meta-analysis

This systematic review and meta-analysis compares the prevalence of bacteremia and bacterial meningitis in febrile neonates vs febrile infants in their second month of life presenting to an ambulatory care setting.

open access
JAMA Netw Open. 2019;2(3):e190874. doi:10.1001/jamanetworkopen.2019.0874
Abstract Full Text pdf link PDF
SUBSTANCE USE AND ADDICTION

Evaluation of Machine-Learning Algorithms for Predicting Opioid Overdose Risk Among Medicare Beneficiaries With Opioid Prescriptions

This prognostic study evaluates the use of machine-learning methods, with prescription drug and claims data, in detecting opioid overdose risk in Medicare beneficiaries with at least 1 opioid prescription.

open access
JAMA Netw Open. 2019;2(3):e190968. doi:10.1001/jamanetworkopen.2019.0968
Abstract Full Text pdf link PDF
MEDICAL JOURNALS AND PUBLISHING

Trends in the Use of Common Words and Patient-Centric Language in the Titles of Medical Journals, 1976-2015

This qualitative study of medical research language assesses changes in 5 medical journals and broader changes in the culture of clinical investigation during the last 40 years.

open access
JAMA Netw Open. 2019;2(3):e191083. doi:10.1001/jamanetworkopen.2019.1083
Abstract Full Text pdf link PDF
GERIATRICS

Assessment of Reported Comparative Effectiveness and Safety of Atypical Antipsychotics in the Treatment of Behavioral and Psychological Symptoms of Dementia: A Network Meta-analysis

This network meta-analysis examines the results of randomized clinical trials that evaluated the effectiveness and safety of atypical antipsychotics in patients with dementia.

open access
JAMA Netw Open. 2019;2(3):e190828. doi:10.1001/jamanetworkopen.2019.0828
Abstract Full Text pdf link PDF
PEDIATRICS

Rates of Extreme Neonatal Hyperbilirubinemia and Kernicterus in Children and Adherence to National Guidelines for Screening, Diagnosis, and Treatment in Sweden

This population-based nationwide cohort study evaluates the incidence rates of hazardous hyperbilirubinemia and kernicterus among near-term to term infants in Sweden and assesses health care professionals’ adherence to best practices.

open access
JAMA Netw Open. 2019;2(3):e190858. doi:10.1001/jamanetworkopen.2019.0858
Abstract Full Text pdf link PDF
PUBLIC HEALTH

HIV Testing and Sexual Health Among Black African Men and Women in London, United Kingdom

This cross-sectional study investigates the proportion of black African adults in London, United Kingdom, who have been tested for HIV in the past 5 years and the proportion living with diagnosed and undiagnosed HIV.

open access
JAMA Netw Open. 2019;2(3):e190864. doi:10.1001/jamanetworkopen.2019.0864
Abstract Full Text pdf link PDF
ONCOLOGY

Association of Chemerin Plasma Concentration With Risk of Colorectal Cancer

This case-cohort study evaluates the association of circulating plasma chemerin concentrations with incident colorectal cancer among adults in the European Prospective Investigation Into Cancer and Nutrition (EPIC)–Potsdam cohort.

open access
JAMA Netw Open. 2019;2(3):e190896. doi:10.1001/jamanetworkopen.2019.0896
Abstract Full Text pdf link PDF
PUBLIC HEALTH

Trends, Regional Variations, and Socioeconomic Disparities in Cesarean Births in India, 2010-2016

This cross-sectional study estimates the rates of cesarean delivery and assesses regional and socioeconomic disparities within these rates among females of child-bearing age in India.

open access
JAMA Netw Open. 2019;2(3):e190526. doi:10.1001/jamanetworkopen.2019.0526
Abstract Full Text pdf link PDF
PEDIATRICS

Association of the Infant Gut Microbiome With Early Childhood Neurodevelopmental Outcomes: An Ancillary Study to the VDAART Randomized Clinical Trial

This ancillary cohort study of the Vitamin D Antenatal Asthma Reduction Trial (VDAART) examines the association of the gut microbiome in infancy with development of motor skills, problem solving, communication, and personal and social skills at preschool age.

open access
JAMA Netw Open. 2019;2(3):e190905. doi:10.1001/jamanetworkopen.2019.0905
Abstract Full Text pdf link PDF
ONCOLOGY

Assessment of Differences in Clinical Activity and Medicare Payments Among Female and Male Radiation Oncologists

This population-based cohort study uses the Centers for Medicare & Medicaid Services Physician and Other Supplier Public Use File to evaluate sex differences among radiation oncologists in productivity, breadth of practice, and payments and to characterize Medicare reimbursement by sex among similar groups of radiation oncologists.

open access
JAMA Netw Open. 2019;2(3):e190932. doi:10.1001/jamanetworkopen.2019.0932
Abstract Full Text pdf link PDF
EMERGENCY MEDICINE

Analysis of Diagnoses, Symptoms, Medications, and Admissions Among Patients With Cancer Presenting to Emergency Departments

This multicenter cohort study identifies the clinical characteristics and needs of adults with active cancer who present to emergency departments (EDs).

open access
JAMA Netw Open. 2019;2(3):e190979. doi:10.1001/jamanetworkopen.2019.0979
Abstract Full Text pdf link PDF
GLOBAL HEALTH

Assessment of Myocardial Function in Kenyan Children With Severe, Acute Malnutrition: The Cardiac Physiology in Malnutrition (CAPMAL) Study

This case-control study examines the risk for cardiac dysfunction in African children hospitalized for severe, acute malnutrition.

open access
JAMA Netw Open. 2019;2(3):e191054. doi:10.1001/jamanetworkopen.2019.1054
Abstract Full Text pdf link PDF
IMAGING

Development and Validation of a Deep Learning–Based Automated Detection Algorithm for Major Thoracic Diseases on Chest Radiographs

This diagnostic study measures the ability of a deep learning–based algorithm to discriminate between chest radiographs with normal results and chest radiographs with abnormal results indicating major thoracic disease.

open access
JAMA Netw Open. 2019;2(3):e191095. doi:10.1001/jamanetworkopen.2019.1095
Abstract Full Text pdf link PDF
HEALTH POLICY

Effect of Financial Incentives on Patient Use of Mailed Colorectal Cancer Screening Tests: A Randomized Clinical Trial

This 4-parallel-arm randomized clinical trial determines the effectiveness of financial incentives on fecal immunochemical test screening completion vs no incentive among adults who were sent kits by mail.

open access
JAMA Netw Open. 2019;2(3):e191156. doi:10.1001/jamanetworkopen.2019.1156
Abstract Full Text pdf link PDF
CORRECTION

Errors in Results, Table 3, and eTables 2 and 3

open access
JAMA Netw Open. 2019;2(3):e191625. doi:10.1001/jamanetworkopen.2019.1625
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CORRECTION

Correction of a Reference

open access
JAMA Netw Open. 2019;2(3):e191971. doi:10.1001/jamanetworkopen.2019.1971
Abstract Full Text pdf link PDF
CORRECTION

Error in Byline

open access
JAMA Netw Open. 2019;2(3):e192366. doi:10.1001/jamanetworkopen.2019.2366
Abstract Full Text pdf link PDF
SUBSTANCE USE AND ADDICTION

Trends and Patterns of Geographic Variation in Opioid Prescribing Practices by State, United States, 2006-2017

This population-based cross-sectional study uses data from the IQVIA Xponent database for all opioid prescriptions filled in the United States from 2006 through 2017 to evaluate national and state trends in amount, dosage, duration, and formulation.

open access
JAMA Netw Open. 2019;2(3):e190665. doi:10.1001/jamanetworkopen.2019.0665
Abstract Full Text pdf link PDF
SUBSTANCE USE AND ADDICTION

Association of Methadone Treatment With Substance-Related Hospital Admissions Among a Population in Canada With a History of Criminal Convictions

This cohort study compares the risk of substance-related acute hospital admission during periods of methadone-medicated vs nonmedicated periods in individuals in Canada with a history of criminal conviction.

open access
JAMA Netw Open. 2019;2(3):e190595. doi:10.1001/jamanetworkopen.2019.0595
Abstract Full Text pdf link PDF
NUTRITION, OBESITY, AND EXERCISE

Association of Light Physical Activity Measured by Accelerometry and Incidence of Coronary Heart Disease and Cardiovascular Disease in Older Women

This cohort study investigates whether higher levels of light physical activity measured by accelerometry are associated with reduced risks of coronary heart disease (CHD) or cardiovascular disease (CVD) in older women.

open access
JAMA Netw Open. 2019;2(3):e190419. doi:10.1001/jamanetworkopen.2019.0419
Abstract Full Text pdf link PDF
CARDIOLOGY

Twenty-Year Trends in Outcomes for Older Adults With Acute Myocardial Infarction in the United States

This cohort study reports patterns of hospitalizations, treatments, and outcomes for US Medicare fee-for-service beneficiaries aged 65 years or older with acute myocardial infarction from 1995 to 2014.

open access
JAMA Netw Open. 2019;2(3):e191938. doi:10.1001/jamanetworkopen.2019.1938
Abstract Full Text pdf link PDF
HEALTH POLICY

Trends and Factors Associated With Physician Burnout at a Multispecialty Academic Faculty Practice Organization

This survey study assesses trends and factors associated with physician burnout in a large academic medical faculty practice.

open access has audio
JAMA Netw Open. 2019;2(3):e190554. doi:10.1001/jamanetworkopen.2019.0554
Abstract Full Text pdf link PDF
NEUROLOGY

Association of Continuous Assessment of Step Count by Remote Monitoring With Disability Progression Among Adults With Multiple Sclerosis

This longitudinal cohort study assesses how remote monitoring of continuous step count activity for 1 year among individuals with multiple sclerosis is associated with other measures of multiple sclerosis disability.

open access
JAMA Netw Open. 2019;2(3):e190570. doi:10.1001/jamanetworkopen.2019.0570
Abstract Full Text pdf link PDF
HEALTH INFORMATICS

Assessment of a Deep Learning Model Based on Electronic Health Record Data to Forecast Clinical Outcomes in Patients With Rheumatoid Arthritis

This prognostic study examines the ability of an artificial intelligence system to predict the state of disease activity in patients with rheumatoid arthritis at their next clinical visit.

open access
JAMA Netw Open. 2019;2(3):e190606. doi:10.1001/jamanetworkopen.2019.0606
Abstract Full Text pdf link PDF
HEALTH POLICY

Thirty-Day Postdischarge Mortality Among Black and White Patients 65 Years and Older in the Medicare Hospital Readmissions Reduction Program

This cohort study uses a time-series analysis to examine differences in mortality and hospital readmissions in black vs white patients 65 years and older after introduction of the Medicare Hospital Readmissions Reduction Program.

open access has audio
JAMA Netw Open. 2019;2(3):e190634. doi:10.1001/jamanetworkopen.2019.0634
Abstract Full Text pdf link PDF
PUBLIC HEALTH

Follow-up of an Intervention to Reduce Dental Caries in Indigenous Australian Children: A Secondary Analysis of a Randomized Clinical Trial

This secondary analysis of a randomized clinical trial investigates the long-term effectiveness of an intervention that aimed to reduce dental caries among South Australian Aboriginal children.

open access
JAMA Netw Open. 2019;2(3):e190648. doi:10.1001/jamanetworkopen.2019.0648
Abstract Full Text pdf link PDF
DIABETES AND ENDOCRINOLOGY

Effectiveness of Targeted Insulin-Adherence Interventions for Glycemic Control Using Predictive Analytics Among Patients With Type 2 Diabetes: A Randomized Clinical Trial

This randomized clinical trial examines the effectiveness of administering a more intensive insulin-adherence intervention only to individuals with type 2 diabetes estimated to benefit based on predictive analytics vs administering a lower-intensity intervention to a larger group of unselected individuals.

open access
JAMA Netw Open. 2019;2(3):e190657. doi:10.1001/jamanetworkopen.2019.0657
Abstract Full Text pdf link PDF
EMERGENCY MEDICINE

Diagnostic Accuracy of Point-of-Care Lung Ultrasonography and Chest Radiography in Adults With Symptoms Suggestive of Acute Decompensated Heart Failure: A Systematic Review and Meta-analysis

This systematic review and meta-analysis compares the accuracy of lung ultrasonography vs chest radiography in the diagnosis of pulmonary edema in acute decompensated heart failure in adults.

open access
JAMA Netw Open. 2019;2(3):e190703. doi:10.1001/jamanetworkopen.2019.0703
Abstract Full Text pdf link PDF
CARDIOLOGY

Association of Weight Fluctuation With Mortality in Japanese Adults

This cohort study of Japanese adults who survived the atomic bomb assesses whether extreme body weight variation is associated with mortality after controlling for nonlinear weight changes.

open access
JAMA Netw Open. 2019;2(3):e190731. doi:10.1001/jamanetworkopen.2019.0731
Abstract Full Text pdf link PDF
PSYCHIATRY

Assessment of a Risk Index for Suicide Attempts Among US Army Soldiers With Suicide Ideation: Analysis of Data From the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS)

This cohort study investigates whether a brief self-report battery from a survey of US Army soldiers is associated with identification of those with suicide ideation who are at the highest risk of suicide attempt.

open access
JAMA Netw Open. 2019;2(3):e190766. doi:10.1001/jamanetworkopen.2019.0766
Abstract Full Text pdf link PDF
CORRECTION

Typographical Error in Title

open access
JAMA Netw Open. 2019;2(3):e192236. doi:10.1001/jamanetworkopen.2019.2236
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CORRECTION

Data Error in Results

open access
JAMA Netw Open. 2019;2(3):e192314. doi:10.1001/jamanetworkopen.2019.2314
Abstract Full Text pdf link PDF
CARDIOLOGY

Association of Leisure-Time Physical Activity Across the Adult Life Course With All-Cause and Cause-Specific Mortality

This cohort study analyzes questionnaire data from the National Institutes of Health–AARP (formerly American Association of Retired Persons) Diet and Health Study to assess whether an association exists between risk of all-cause, cardiovascular disease–related, or cancer-related mortality and self-reported leisure-time physical activity patterns across the life course.

open access
JAMA Netw Open. 2019;2(3):e190355. doi:10.1001/jamanetworkopen.2019.0355
Abstract Full Text pdf link PDF
HEALTH POLICY

Race/Ethnicity and Geographic Access to Urban Trauma Care

This cross-sectional study examines whether there is an association between race/ethnicity and access to level I and level II trauma centers within Chicago, Illinois; New York, New York; and Los Angeles, California.

open access
JAMA Netw Open. 2019;2(3):e190138. doi:10.1001/jamanetworkopen.2019.0138
Abstract Full Text pdf link PDF
HEALTH INFORMATICS

Assessment of Employee Susceptibility to Phishing Attacks at US Health Care Institutions

This multicenter quality improvement study type describes the practice of phishing simulation and the extent to which health care employees are vulnerable to phishing simulations.

open access
JAMA Netw Open. 2019;2(3):e190393. doi:10.1001/jamanetworkopen.2019.0393
Abstract Full Text pdf link PDF
CARDIOLOGY

Assessment of Risk of Harm Associated With Intensive Blood Pressure Management Among Patients With Hypertension Who Smoke: A Secondary Analysis of the Systolic Blood Pressure Intervention Trial

This secondary analysis of the Systolic Blood Pressure Intervention Trial uses a random forest–based analysis to assess whether clinically important heterogeneity exists in the risk of harm associated with intensive blood pressure treatment among adults with hypertension who smoke.

open access
JAMA Netw Open. 2019;2(3):e190005. doi:10.1001/jamanetworkopen.2019.0005
Abstract Full Text pdf link PDF
STATISTICS AND RESEARCH METHODS

Combined Association of Body Mass Index and Alcohol Consumption With Biomarkers for Liver Injury and Incidence of Liver Disease: A Mendelian Randomization Study

This population-based cohort study uses mendelian randomization to examine the association of body mass index (BMI) and alcohol consumption with levels of liver injury biomarkers and incident liver disease in adults in Denmark.

open access
JAMA Netw Open. 2019;2(3):e190305. doi:10.1001/jamanetworkopen.2019.0305
Abstract Full Text pdf link PDF
ENVIRONMENTAL HEALTH

Association of Long-term Exposure to Ambient Air Pollutants With Risk Factors for Cardiovascular Disease in China

This population-based cross-sectional study evaluates the associations of long-term exposures to air pollutants with cardiometabolic risk factors and prevalence of cardiovascular disease among adults in China.

open access
JAMA Netw Open. 2019;2(3):e190318. doi:10.1001/jamanetworkopen.2019.0318
Abstract Full Text pdf link PDF
SUBSTANCE USE AND ADDICTION

Association of Criminal Statutes for Opioid Use Disorder With Prevalence and Treatment Among Pregnant Women With Commercial Insurance in the United States

This cohort study examines data from the IQVIA PharMetrics Plus database for prevalence of opioid use disorder and treatment among a random sample of privately insured pregnant women in 4 regions across the United States.

open access
JAMA Netw Open. 2019;2(3):e190338. doi:10.1001/jamanetworkopen.2019.0338
Abstract Full Text pdf link PDF
HEALTH INFORMATICS

Assessment of Machine Learning vs Standard Prediction Rules for Predicting Hospital Readmissions

This prognostic study compares standard readmission risk assessment scores with a machine learning score, the Baltimore score, for predicting 30-day unplanned hospital readmissions calculated in real time.

open access
JAMA Netw Open. 2019;2(3):e190348. doi:10.1001/jamanetworkopen.2019.0348
Abstract Full Text pdf link PDF
CARDIOLOGY

Prevalence of Hypertension, Treatment, and Blood Pressure Targets in Canada Associated With the 2017 American College of Cardiology and American Heart Association Blood Pressure Guidelines

This cross-sectional study evaluates the potential change in the diagnosis, treatment, and control of hypertension in a Canadian cohort of patients with hypertension attending primary care practices using the 2017 American College of Cardiology and American Heart Association (ACC/AHA) guidelines.

open access
JAMA Netw Open. 2019;2(3):e190406. doi:10.1001/jamanetworkopen.2019.0406
Abstract Full Text pdf link PDF
ONCOLOGY

Association of Bone Metastasis With Early-Stage Breast Cancer in Women With and Without Precancer Osteoporosis According to Osteoporosis Therapy Status

This cohort study investigates whether precancer osteoporosis and osteoporosis therapy are associated with bone metastasis patterns in patients with breast cancer.

open access
JAMA Netw Open. 2019;2(3):e190429. doi:10.1001/jamanetworkopen.2019.0429
Abstract Full Text pdf link PDF
HEALTH INFORMATICS

Comparison of Artificial Intelligence Techniques to Evaluate Performance of a Classifier for Automatic Grading of Prostate Cancer From Digitized Histopathologic Images

This quality improvement study compares several artificial intelligence (AI) cross-validation approaches to evaluate the performance of a classifier for automatic grading of prostate cancer in digitized histopathologic images, both when trained using data from 1 expert and when trained using data from multiple experts.

open access
JAMA Netw Open. 2019;2(3):e190442. doi:10.1001/jamanetworkopen.2019.0442
Abstract Full Text pdf link PDF
CORRECTION

Omission of Affiliations

open access
JAMA Netw Open. 2019;2(3):e191249. doi:10.1001/jamanetworkopen.2019.1249
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HEALTH INFORMATICS

Comparative Accuracy of Diagnosis by Collective Intelligence of Multiple Physicians vs Individual Physicians

This cross-sectional study uses cases from the Human Diagnosis Project to compare the accuracy of single-physicians’ diagnoses with pooled diagnoses from groups of physicians.

open access
JAMA Netw Open. 2019;2(3):e190096. doi:10.1001/jamanetworkopen.2019.0096
Abstract Full Text pdf link PDF
EDITORIAL

Collective Intelligence for Clinical Diagnosis—Are 2 (or 3) Heads Better Than 1?

open access
JAMA Netw Open. 2019;2(3):e191071. doi:10.1001/jamanetworkopen.2019.1071
Abstract Full Text pdf link PDF
PSYCHIATRY

Effectiveness of Implementing a Collaborative Chronic Care Model for Clinician Teams on Patient Outcomes and Health Status in Mental Health: A Randomized Clinical Trial

This randomized clinical trial reports the process and outcomes of establishing the collaborative chronic care model in 9 mental health facilities within the US Department of Veterans Affairs system.

open access
JAMA Netw Open. 2019;2(3):e190230. doi:10.1001/jamanetworkopen.2019.0230
Abstract Full Text pdf link PDF
ONCOLOGY

Development and Validation of a Multivariable Lung Cancer Risk Prediction Model That Includes Low-Dose Computed Tomography Screening Results: A Secondary Analysis of Data From the National Lung Screening Trial

This secondary analysis of data from the National Lung Screening Trial develops and validates a risk prediction model that incorporates low-dose computed tomography (CT) screening results for patients being screened for lung cancer.

open access
JAMA Netw Open. 2019;2(3):e190204. doi:10.1001/jamanetworkopen.2019.0204
Abstract Full Text pdf link PDF
PULMONARY MEDICINE

Association of Long-term Use of Low-Dose Aspirin as Chemoprevention With Risk of Lung Cancer

This nationwide, population-based cohort study uses data from the Korean National Health Information Database to assess whether an association exists between low-dose aspirin use and lung cancer risk and to identify specific subgroups that may benefit most from low-dose aspirin use.

open access
JAMA Netw Open. 2019;2(3):e190185. doi:10.1001/jamanetworkopen.2019.0185
Abstract Full Text pdf link PDF
PHARMACY AND CLINICAL PHARMACOLOGY

Association of Antidementia Therapies With Time to Skilled Nursing Facility Admission and Cardiovascular Events Among Elderly Adults With Alzheimer Disease

This cohort study uses Medicare data to compare time to skilled nursing facility admission and cardiovascular (CV) events among patients with Alzheimer disease receiving acetylcholinesterase inhibitor monotherapy, memantine monotherapy, or combination acetylcholinesterase inhibitor and memantine therapy.

open access
JAMA Netw Open. 2019;2(3):e190213. doi:10.1001/jamanetworkopen.2019.0213
Abstract Full Text pdf link PDF
PSYCHIATRY

Family History of Mental and Neurological Disorders and Risk of Autism

This population-based cohort study examines family history of mental and neurological disorders among first- to fourth-degree relatives and risk of autism spectrum disorders with and without intellectual disability in index persons from the Stockholm Youth Cohort in Sweden.

open access
JAMA Netw Open. 2019;2(3):e190154. doi:10.1001/jamanetworkopen.2019.0154
Abstract Full Text pdf link PDF
ANESTHESIOLOGY

Factors Associated With Acute Pain Estimation, Postoperative Pain Resolution, Opioid Cessation, and Recovery: Secondary Analysis of a Randomized Clinical Trial

This secondary analysis of a randomized clinical trial examines levels of postoperative pain to identify a factor that may be associated with the probability of pain cessation, opioid cessation, and recovery.

open access
JAMA Netw Open. 2019;2(3):e190168. doi:10.1001/jamanetworkopen.2019.0168
Abstract Full Text pdf link PDF
HEMATOLOGY

Risk-Dependent Conditional Survival and Failure Hazard After Radiotherapy for Early-Stage Extranodal Natural Killer/T-Cell Lymphoma

This cohort study assesses changes in survival probabilities and failure hazard after radiotherapy in adult patients with early-stage extranodal natural killer/T-cell lymphoma based on risk categories, previous survival, and treatment.

open access
JAMA Netw Open. 2019;2(3):e190194. doi:10.1001/jamanetworkopen.2019.0194
Abstract Full Text pdf link PDF
NEUROLOGY

Assessment of Vascular Event Prevention and Cognitive Function Among Older Adults With Preexisting Vascular Disease or Diabetes: A Secondary Analysis of 3 Randomized Clinical Trials

This secondary analysis of 3 randomized clinical trials estimates the effect on cognitive aging of the avoidance of vascular events and evaluates whether reports of nonsignificant results exclude worthwhile benefit among patients with vascular disease.

open access
JAMA Netw Open. 2019;2(3):e190223. doi:10.1001/jamanetworkopen.2019.0223
Abstract Full Text pdf link PDF
CORRECTION

Incorrect Number of Tramadol Tablets Prescribed

open access
JAMA Netw Open. 2019;2(3):e190772. doi:10.1001/jamanetworkopen.2019.0772
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CORRECTION

Errors in Results, Table, and Figure

open access
JAMA Netw Open. 2019;2(3):e190147. doi:10.1001/jamanetworkopen.2019.0147
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CORRECTION

Incorrect Column Headings in 2 Tables

open access
JAMA Netw Open. 2019;2(3):e191203. doi:10.1001/jamanetworkopen.2019.1203
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JAMA Network Open Masthead

JAMA Network Open

open access
JAMA Netw Open. 2019;2(3):e187892. doi:10.1001/jamanetworkopen.2018.7892
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