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Xie J, Tong Z, Guan X, Du B, Qiu H. Clinical Characteristics of Patients Who Died of Coronavirus Disease 2019 in China. JAMA Netw Open. 2020;3(4):e205619. doi:10.1001/jamanetworkopen.2020.5619
The outbreak of coronavirus disease 2019 (COVID-19) has been very severe in China.1 As of March 2020, many tens of thousands of patients have had confirmed COVID-19, and cases have been increasing daily.2 The mortality is much higher in Wuhan, China, than in other cities.3 To understand the characteristics of patients who die of COVID-19, we analyzed 168 patients with COVID-19–induced pneumonia who died.
This case series’ study protocol was approved by each local institutional ethics committees. Written informed consent was waived owing to the urgent need to collect data. Data were obtained from 21 hospitals in Wuhan, China. Demographic, comorbidity, and respiratory support data for 168 patients who died of COVID-19 between January 21 to 30, 2020, in these hospitals were collected. All patients were diagnosed as having COVID-19 according to World Health Organization guidance.3 All patients underwent nucleic acid testing by reverse transcription–polymerase chain reaction testing, and their results were positive for COVID-19. Categorical variables were described as numbers (proportions) and continuous variables were described as medians and interquartile ranges (IQRs). Data were analyzed from February 8 to February 10, 2020.
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