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    3 Comments for this article
    Follow-up Study RE Transmission
    Ruth Son, Masters | York University
    I am curious to know if the authors plan to see if collected virus samples can be grown in a viral culture, or if a follow-up study looking at if it can be transmitted this way will be conducted.
    COVID-19 in semen
    Joao Sabino Lahorgue Da Cunha Filho jfilho, MD, PhD | Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
    The paper from Li et al opened a new discussion about the potential effect of COVID-19 in human reproduction 1. As expected and demonstrated by others, HIV for example, is present in semen; however, using a proper treatment the sexual transmission is controlled. Moreover, the assisted reproductive techniques can be safely done in HIV discordant patients after semen preparation 2–4. Therefore, it is plausible that COVID-19 was present in semen, but it does not means a sexual transmission. Next we should investigate better COVID-19 semen concentration regarding serum viral load and disease stage.

    1. Li D,
    Jin M, Bao P, Zhao W, Zhang S. Clinical Characteristics and Results of Semen Tests Among Men With Coronavirus Disease 2019. JAMA Netw Open. 2020;3(5):e208292.
    2. Arenas-Pinto A, Stöhr W, Khoo S, et al. Genital secretion HIV RNA shedding in HIV-positive patients on ritonavir-boosted protease inhibitor monotherapy or standard combination ART: a cross-sectional sub-study from the PIVOT Trial. Antivir Ther. March 2020. doi:10.3851/IMP3340
    3. Carvalho W de AP de, Catafesta E, Rodart IF, Takata S, Estevam DL, Barbosa CP. Prevention of HIV transmission with sperm washing within fertile serodiscordant couples undergoing non-stimulated intrauterine insemination. AIDS Care. March 2020:1-8.
    4. Kariuki SM, Selhorst P, Norman J, et al. Detectable HIV-1 in semen in individuals with very low blood viral loads. Virol J. 2020;17(1):29.
    The virus may also escape to other immunoprivileged organs
    Robert Eibl, Dr. med. | German cancer research center alumni association, Heidelberg
    It will be interesting to check other organs like the eye and the brain.
    Research Letter
    Infectious Diseases
    May 7, 2020

    Clinical Characteristics and Results of Semen Tests Among Men With Coronavirus Disease 2019

    Author Affiliations
    • 1Nanlou Respiratory Diseases Department, Chinese People’s Liberation Army General Hospital, Beijing, China
    • 2Department of Nephrology, Chinese People’s Liberation Army General Hospital, Chinese People’s Liberation Army Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Chinese People’s Liberation Army Postgraduate Medical School, Beijing, China
    • 3Department of Nephrology, Beijing-Chaoyang Hospital, Beijing, China
    • 4Department of Respiratory Medicine, The Eighth Medical Center of Chinese People’s Liberation Army General Hospital, Beijing, China
    • 5Shangqiu Municipal Hospital, Shangqiu, China
    JAMA Netw Open. 2020;3(5):e208292. doi:10.1001/jamanetworkopen.2020.8292

    In December 2019, an outbreak of pneumonia associated with coronavirus disease 2019 (COVID-19) occurred in Wuhan, China, and rapidly spread to other parts of China and overseas.1 It has been confirmed that COVID-19 has the characteristic of human-to-human transmission, mainly through respiratory droplets and contact. Other routes require further verification. The virus responsible for COVID-19, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been detected in stool, gastrointestinal tract, saliva, and urine samples.2 However, little is known about SARS-CoV-2 in semen.

    This cohort study was performed after patients gave written informed consent for research purposes, and in compliance with the Helsinki Declaration3 with the approval of the ethics committee of Shangqiu Municipal Hospital, Shangqiu, China. This study is reported following the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) reporting guideline.