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Shinall MC, Youk A, Massarweh NN, et al. Association of Preoperative Frailty and Operative Stress With Mortality After Elective vs Emergency Surgery. JAMA Netw Open. 2020;3(7):e2010358. doi:10.1001/jamanetworkopen.2020.10358
Our group recently examined the associations among preoperative frailty, operative stress, and postoperative mortality in a retrospective cohort published in JAMA Surgery.1 Frail and very frail patients had high mortality rates at 30, 90, and 180 days even after low-stress operations, a finding that triggered questions about whether inclusion of patients undergoing emergency operations may have been associated with the high mortality rate. We hypothesized that postoperative mortality would increase with increasing frailty and increasing operative stress for both elective and emergent operations, with high levels of mortality for frail and very frail patients even after low-stress, elective operations.
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