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Invited Commentary
July 23, 2020

Evidence Supporting the Use of Inferior Vena Cava Filters in Patients With Cancer—Coming Into Focus

Author Affiliations
  • 1Section of Vascular Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire
JAMA Netw Open. 2020;3(7):e2011942. doi:10.1001/jamanetworkopen.2020.11942

Venous thromboembolism (VTE) is a frequent complication of cancer and carries a significant risk of mortality.1 Anticoagulation serves as the mainstay of treatment for VTE in patients with cancer and deep venous thrombosis (DVT) or pulmonary embolus (PE), but the associated risk of bleeding may be prohibitive in some patients. In this situation, or in a scenario wherein patients experience recurrent or progressive VTE despite anticoagulation, inferior vena cava (IVC) filters may be used as a means of mechanical thromboprophylaxis. Placement of an IVC filter itself, though, is not without risk. The evidence to support the use of IVC filters in patients with cancer, specifically, is limited.

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