Age- and Sex-Associated Variations in the Sensitivity of Serological Tests Among Individuals Infected With SARS-CoV-2 | Infectious Diseases | JAMA Network Open | JAMA Network
[Skip to Navigation]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
Limit 200 characters
Limit 25 characters
Conflicts of Interest Disclosure

Identify all potential conflicts of interest that might be relevant to your comment.

Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.

Err on the side of full disclosure.

If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.

Not all submitted comments are published. Please see our commenting policy for details.

Limit 140 characters
Limit 3600 characters or approximately 600 words
    Views 10,685
    Citations 0
    Research Letter
    Infectious Diseases
    February 12, 2021

    Age- and Sex-Associated Variations in the Sensitivity of Serological Tests Among Individuals Infected With SARS-CoV-2

    Author Affiliations
    • 1Bakar Computational Health Sciences Institute, University of California, San Francisco
    • 2Center for Data-driven Insights and Innovation, University of California Health, Oakland
    • 3Department of Pathology and Laboratory Medicine, University of California, Irvine
    • 4Department of Pathology and Laboratory Medicine, UCLA Medical Center, Los Angeles, California
    JAMA Netw Open. 2021;4(2):e210337. doi:10.1001/jamanetworkopen.2021.0337

    Antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are known to appear 2 to 3 weeks after infection,1-3 but patient characteristics and measurement timing could influence this immune response. This cohort study investigated the sensitivity of antibody tests to detect previous SARS-CoV-2 infection using existing clinical data across the University of California Health (UC Health) system.

    The institutional review boards across the UC Health system determined this cohort study was not human participants research and therefore was exempt from approval and informed consent. This study is reported following the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) reporting guideline.