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May 2019 - May 2018

Decade

Year

Issue

August 2018, Vol 1, No. 4

open access Original Investigation

CARDIOLOGY

Comparison of Clinical Outcomes Among Patients With Atrial Fibrillation or Atrial Flutter Stratified by CHA2DS2-VASc Score

This cohort study uses Taiwan National Health Insurance database data to evaluate the incidence of ischemic stroke, hospitalization for heart failure, and all-cause mortality among patients with atrial fibrillation and atrial flutter stratified by CHA2DS2-VASc score.

JAMA Netw Open. 2018;1(4):e180941. doi:10.1001/jamanetworkopen.2018.0941
Abstract Full Text pdf link PDF

NUTRITION, OBESITY, AND EXERCISE

Association of Neighborhood Geographic Spatial Factors With Rates of Childhood Obesity

This study uses census block data in Arkansas to investigate spatial patterns in childhood obesity between the 2003-2004 and 2014-2015 academic years and to distinguish obesity risk attributable to social contagion vs neighborhood contextual factors.

JAMA Netw Open. 2018;1(4):e180954. doi:10.1001/jamanetworkopen.2018.0954
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Assessment of Environmental Sustainability and Corporate Social Responsibility Reporting by Large Health Care Organizations

This study characterizes environmental sustainability and corporate social responsibility (CSR) reporting by US health care organizations (HCOs) named by Fortune 500, Forbes, and other financial sources as the largest US HCOs in 2015 or 2016 and compares CSR reporting trends among those HCOs with reporting in other economic sectors.

JAMA Netw Open. 2018;1(4):e180975. doi:10.1001/jamanetworkopen.2018.0975
Abstract Full Text pdf link PDF

HEALTH POLICY

Perceptions of Factors Associated With Inclusive Work and Learning Environments in Health Care Organizations: A Qualitative Narrative Analysis

This qualitative analysis of health care student and professional responses to questions about inclusion and respect in respondents’ hospitals and health schools describes factors influencing their perceptions and strategies to improve inclusion and retain a diverse health care workforce.

JAMA Netw Open. 2018;1(4):e181003. doi:10.1001/jamanetworkopen.2018.1003
Abstract Full Text pdf link PDF

HEALTH INFORMATICS

Development and Validation of an Electronic Health Record–Based Machine Learning Model to Estimate Delirium Risk in Newly Hospitalized Patients Without Known Cognitive Impairment

This study describes the development and prognostic accuracy of 5 machine learning models designed to predict incident delirium in newly hospitalized patients without known cognitive impairment using clinical variables derived from the patients’ electronic health record (EHR).

JAMA Netw Open. 2018;1(4):e181018. doi:10.1001/jamanetworkopen.2018.1018
Abstract Full Text pdf link PDF

GASTROENTEROLOGY AND HEPATOLOGY

Survival Rates for Patients With Barrett High-grade Dysplasia and Esophageal Adenocarcinoma With or Without Human Papillomavirus Infection

This case-control study compares disease-free and overall survival among patients with Barrett high-grade dysplasia or esophageal adenocarcinoma with vs without underlying human papillomavirus (HPV) infection demonstrated on biopsy.

JAMA Netw Open. 2018;1(4):e181054. doi:10.1001/jamanetworkopen.2018.1054
Abstract Full Text pdf link PDF

MEDICAL JOURNALS AND PUBLISHING

Age of Data at the Time of Publication of Contemporary Clinical Trials

This cross-sectional analysis characterizes the age of clinical trial data at the time of publication in journals with a high impact factor and examines the time from final data collection to publication.

JAMA Netw Open. 2018;1(4):e181065. doi:10.1001/jamanetworkopen.2018.1065
Abstract Full Text pdf link PDF

GLOBAL HEALTH

Global Development Assistance for Adolescent Health From 2003 to 2015

This quality improvement study estimates flows of total development assistance for adolescent health and per-adolescent development assistance for adolescent health and assesses its distribution by donors, regions, and countries and the leading causes of burden of disease in 132 developing countries.

JAMA Netw Open. 2018;1(4):e181072. doi:10.1001/jamanetworkopen.2018.1072
Abstract Full Text pdf link PDF

CARDIOLOGY

Risk Factors Associated With Major Cardiovascular Events 1 Year After Acute Myocardial Infarction

This cohort study identifies risk factors associated with major cardiovascular events within 1 year of acute myocardial infarction in Chinese patients and describes the development and evaluation of a risk model to predict such events.

JAMA Netw Open. 2018;1(4):e181079. doi:10.1001/jamanetworkopen.2018.1079
Abstract Full Text pdf link PDF

ONCOLOGY

Association of Radiotherapy With Survival in Women Treated for Ductal Carcinoma In Situ With Lumpectomy or Mastectomy

This cohort study uses data from the Surveillance, Epidemiology, and End Results (SEER) 18 database to compare rates of survival among women with ductal carcinoma in situ (DCIS) who were treated with radiotherapy after lumpectomy vs lumpectomy or mastectomy alone.

JAMA Netw Open. 2018;1(4):e181100. doi:10.1001/jamanetworkopen.2018.1100
Abstract Full Text pdf link PDF

CRITICAL CARE MEDICINE

Trends in Use of Daily Chest Radiographs Among US Adults Receiving Mechanical Ventilation

This cohort study determines the frequency of daily chest radiograph use for adult patients receiving mechanical ventilation in the United States, assesses variability across hospitals, and evaluates whether use has decreased over time.

JAMA Netw Open. 2018;1(4):e181119. doi:10.1001/jamanetworkopen.2018.1119
Abstract Full Text pdf link PDF

PSYCHIATRY

Prevalence of and Factors Associated With Long-term Concurrent Use of Stimulants and Opioids Among Adults With Attention-Deficit/Hyperactivity Disorder

This cross-sectional analysis of US Medicaid files from 29 states investigates the prevalence of and risk factors associated with concurrent stimulant and opioid use among Medicaid-enrolled adults with attention-deficit/hyperactivity disorder.

JAMA Netw Open. 2018;1(4):e181152. doi:10.1001/jamanetworkopen.2018.1152
Abstract Full Text pdf link PDF

ANESTHESIOLOGY

Effects of a Hypnosis Session Before General Anesthesia on Postoperative Outcomes in Patients Who Underwent Minor Breast Cancer Surgery: The HYPNOSEIN Randomized Clinical Trial

This randomized clinical trial compares the efficacy of preoperative hypnosis vs usual care for reducing postoperative breast pain in patients undergoing breast cancer tumor removal with or without limited axillary node dissection.

JAMA Netw Open. 2018;1(4):e181164. doi:10.1001/jamanetworkopen.2018.1164
Abstract Full Text pdf link PDF

IMAGING

Association Between Guideline-Discordant Prostate Cancer Imaging Rates and Health Care Service Among Veterans and Medicare Recipients

This cohort study compares receipt of National Comprehensive Cancer Network (NCCN) guideline–discordant prostate cancer imaging (radionuclide, CT, or MRI) to stage incident prostate cancer among men being treated in the Veterans Health Administration system vs those receiving Medicare-covered services vs a combination of the two.

JAMA Netw Open. 2018;1(4):e181172. doi:10.1001/jamanetworkopen.2018.1172
Abstract Full Text pdf link PDF

NEUROLOGY

Estimates and Temporal Trend for US Nationwide 30-Day Hospital Readmission Among Patients With Ischemic and Hemorrhagic Stroke

This population-based cohort study uses AHRQ National Readmission Database data to characterize trends in overall, planned, and potentially preventable 30-day hospital readmission rates among patients with ischemic and hemorrhagic stroke between 2010 and September 2015.

JAMA Netw Open. 2018;1(4):e181190. doi:10.1001/jamanetworkopen.2018.1190
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Effect of a Behavioral Intervention on Perpetrating and Experiencing Forced Sex Among South African Adolescents: A Secondary Analysis of a Cluster Randomized Trial

This secondary analysis of a cluster randomized clinical trial evaluates whether an HIV/sexually transmitted disease (STD) risk-reduction intervention shown to reduce sexual risk behavior and STD prevalence among South African adolescents also reduced the perpetration and experience of forced sex.

JAMA Netw Open. 2018;1(4):e181213. doi:10.1001/jamanetworkopen.2018.1213
Abstract Full Text pdf link PDF

HEALTH POLICY

Geographic Distribution and Survival Outcomes for Rural Patients With Cancer Treated in Clinical Trials

This pooled cohort study compares overall, progression-free, and cancer-specific survival of patients living in rural vs urban settings who were enrolled in phase 2 and 3 SWOG treatment trials between 1986 and 2012.

JAMA Netw Open. 2018;1(4):e181235. doi:10.1001/jamanetworkopen.2018.1235
Abstract Full Text pdf link PDF

CARDIOLOGY

Association of Body Mass Index With Blood Pressure Among 1.7 Million Chinese Adults

This population-based cross-sectional study of 1.7 million Chinese adults assesses the association between body mass index (BMI), blood pressure, and hypertension across subgroups of age, sex, income, race, smoking, stroke, and more.

JAMA Netw Open. 2018;1(4):e181271. doi:10.1001/jamanetworkopen.2018.1271
Abstract Full Text pdf link PDF

CARDIOLOGY

Association of Mortality and Acute Aortic Events With Ascending Aortic Aneurysm: A Systematic Review and Meta-analysis

This systematic review and meta-analysis examines 20 studies including 8800 patients with ascending aortic aneurysm (AsAA) to determine the growth rate of aneurysms; the risk of all-cause mortality, aortic dissection, and aortic rupture; and the incidence of elective surgery in AsAA with tricuspid aortic valve (TAV) or bicuspid aortic valve (BAV).

JAMA Netw Open. 2018;1(4):e181281. doi:10.1001/jamanetworkopen.2018.1281
Abstract Full Text pdf link PDF

HEALTH POLICY

Association of State Medicaid Expansion With Rate of Uninsured Hospitalizations for Major Cardiovascular Events, 2009-2014

This cohort study uses data from the HCUP Project State Inpatient Databases to compare the mean payer mix proportions and in-hospital mortality rates of 17 expansion states vs 13 nonexpansion states for the 4 years preceding and the year after the Affordable Care Act Medicaid expansion.

JAMA Netw Open. 2018;1(4):e181296. doi:10.1001/jamanetworkopen.2018.1296
Abstract Full Text pdf link PDF

SUBSTANCE USE AND ADDICTION

Association of Reduced Nicotine Content Cigarettes With Smoking Behaviors and Biomarkers of Exposure Among Slow and Fast Nicotine Metabolizers: A Nonrandomized Clinical Trial

This nonrandomized clinical trial of daily cigarette smokers evaluates the association of use of reduced nicotine content cigarettes with smoking behaviors and biomarkers of exposure by smokers with fast vs slow nicotine metabolism.

JAMA Netw Open. 2018;1(4):e181346. doi:10.1001/jamanetworkopen.2018.1346
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Rotavirus Gastroenteritis Infection Among Children Vaccinated and Unvaccinated With Rotavirus Vaccine in Southern China: A Population-Based Assessment

This cross-sectional, ecological study examines the age at onset and seasonal distribution of rotavirus gastroenteritis incidence among children in China vaccinated with the Lanzhou lamb rotavirus vaccine vs those ineligible for vaccination.

JAMA Netw Open. 2018;1(4):e181382. doi:10.1001/jamanetworkopen.2018.1382
Abstract Full Text pdf link PDF

ONCOLOGY

Association of Long-term Outcomes and Survival With Multidisciplinary Salvage Treatment for Local and Regional Recurrence After Stereotactic Ablative Radiotherapy for Early-Stage Lung Cancer

This cohort study examines long-term outcomes for patients with isolated local recurrence or isolated regional recurrence after stereotactic ablative radiotherapy for early-stage non–small cell lung cancer with the aim of informing treatment decision making.

JAMA Netw Open. 2018;1(4):e181390. doi:10.1001/jamanetworkopen.2018.1390
Abstract Full Text pdf link PDF

GERIATRICS

Performance of Electronic Prediction Rules for Prevalent Delirium at Hospital Admission

This diagnostic study of hospitalized veterans uses the UK National Institute for Health and Clinical Excellence (NICE) framework and delirium clinical practice guidelines to compare the performance of prediction rules for prevalent delirium among older adults at hospital admission.

JAMA Netw Open. 2018;1(4):e181405. doi:10.1001/jamanetworkopen.2018.1405
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

Association of Impaired Cytochrome P450 2D6 Activity Genotype and Phenotype With Therapeutic Efficacy of Primaquine Treatment for Latent Plasmodium vivax Malaria

This nested case-control study explores the association of impaired CYP2D6 genotype and metabolic phenotype activity with failure of high-dose primaquine treatment for Plasmodium vivax malaria relapse in Indonesian men.

JAMA Netw Open. 2018;1(4):e181449. doi:10.1001/jamanetworkopen.2018.1449
Abstract Full Text pdf link PDF

CARDIOLOGY

Variability in Ejection Fraction Measured By Echocardiography, Gated Single-Photon Emission Computed Tomography, and Cardiac Magnetic Resonance in Patients With Coronary Artery Disease and Left Ventricular Dysfunction

This multicenter diagnostic study determines the intermodality variability of left ventricular ejection fraction (LVEF) measured by echocardiography, gated single-photon emission computed tomography (SPECT), and cardiovascular magnetic resonance (CMR) in patients with coronary artery disease and left ventricular dysfunction.

JAMA Netw Open. 2018;1(4):e181456. doi:10.1001/jamanetworkopen.2018.1456
Abstract Full Text pdf link PDF

PSYCHIATRY

Association Between Autism Spectrum Disorders With or Without Intellectual Disability and Depression in Young Adulthood

This population-based cohort study with a nested sibling comparison examines whether Swedish individuals with autism spectrum disorders are more likely to be diagnosed as having depression in adulthood than the general population and their nonautistic siblings and investigates whether these risks differ by the presence or absence of intellectual disability.

JAMA Netw Open. 2018;1(4):e181465. doi:10.1001/jamanetworkopen.2018.1465
Abstract Full Text pdf link PDF

PEDIATRICS

Twenty-Year Trends in Diagnosed Attention-Deficit/Hyperactivity Disorder Among US Children and Adolescents, 1997-2016

This survey study uses data from the National Health Interview Survey to examine changes in the prevalence of diagnosed attention-deficit/hyperactivity disorder (ADHD) in US children and adolescents over a 20-year period, from 1997 to 2016.

JAMA Netw Open. 2018;1(4):e181471. doi:10.1001/jamanetworkopen.2018.1471
Abstract Full Text pdf link PDF

ENVIRONMENTAL HEALTH

Association of Perfluoroalkyl and Polyfluoroalkyl Substances With Adiposity

This cohort study from the Diabetes Prevention Program trial and Outcomes Study determines the extent to which perfluoroalkyl and polyfluoroalkyl substances are associated with increases in body weight and size and evaluates whether a lifestyle intervention modifies this association.

JAMA Netw Open. 2018;1(4):e181493. doi:10.1001/jamanetworkopen.2018.1493
Abstract Full Text pdf link PDF

HEALTH INFORMATICS

Use of Deep Learning to Examine the Association of the Built Environment With Prevalence of Neighborhood Adult Obesity

This cross-sectional modeling study assesses features in the built environment and provides associations with obesity prevalence at the census tract level for 6 US cities.

JAMA Netw Open. 2018;1(4):e181535. doi:10.1001/jamanetworkopen.2018.1535
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

Clinical Features and Complications of Coxiella burnetii Infections From the French National Reference Center for Q Fever

This cohort study describes the clinical characteristics and identifies risk factors for complications and death among a large sample of French patients with Q fever.

JAMA Netw Open. 2018;1(4):e181580. doi:10.1001/jamanetworkopen.2018.1580
Abstract Full Text pdf link PDF

SUBSTANCE USE AND ADDICTION

Changes in Buprenorphine-Naloxone and Opioid Pain Reliever Prescriptions After the Affordable Care Act Medicaid Expansion

This pharmacoepidemiology study compares changes in prescriptions for opioid pain relievers and for buprenorphine with naloxone in 5 states that did vs did not expand Medicaid under the Affordable Care Act (ACA) in 2014.

JAMA Netw Open. 2018;1(4):e181588. doi:10.1001/jamanetworkopen.2018.1588
Abstract Full Text pdf link PDF

HEALTH POLICY

Association of Access to Family Planning Services With Medicaid Expansion Among Female Enrollees in Michigan

This survey study evaluates the association of Medicaid expansion coverage with improved access to birth control and family planning services among women of reproductive age recently enrolled in the Healthy Michigan Plan.

JAMA Netw Open. 2018;1(4):e181627. doi:10.1001/jamanetworkopen.2018.1627
Abstract Full Text pdf link PDF

GLOBAL HEALTH

Prevalence and Estimated Economic Burden of Substandard and Falsified Medicines in Low- and Middle-Income Countries: A Systematic Review and Meta-analysis

This systematic review and meta-analysis examines 96 studies of substandard and falsified medicines in low- and middle-income countries to determine the prevalence and estimated economic burden of these medicines.

JAMA Netw Open. 2018;1(4):e181662. doi:10.1001/jamanetworkopen.2018.1662
Abstract Full Text pdf link PDF

GENETICS AND GENOMICS

Sex Differences in Genetic Associations With Longevity

This population-based case-control study of Chinese Longitudinal Healthy Longevity Study participants uses sex-specific genome-wide association study (GWAS) and polygenic risk score (PRS) analyses to examine sex differences in genetic associations with longevity by comparing participants older than 100 years with a control group of participants aged 40 to 64 years.

JAMA Netw Open. 2018;1(4):e181670. doi:10.1001/jamanetworkopen.2018.1670
Abstract Full Text pdf link PDF

DIABETES AND ENDOCRINOLOGY

Association of Hemoglobin A1c Levels With Use of Sulfonylureas, Dipeptidyl Peptidase 4 Inhibitors, and Thiazolidinediones in Patients With Type 2 Diabetes Treated With Metformin: Analysis From the Observational Health Data Sciences and Informatics Initiative

This multinational cohort study examines the association of second-line treatment (sulfonylureas, dipeptidyl peptidase 4 inhibitors [DPP-4], or thiazolidinediones) for type 2 diabetes after initial therapy with metformin with hemoglobin A1c (HbA1c) levels.

JAMA Netw Open. 2018;1(4):e181755. doi:10.1001/jamanetworkopen.2018.1755
Abstract Full Text pdf link PDF
open access Invited Commentary

PUBLIC HEALTH

How Healthy Is Health Care?

JAMA Netw Open. 2018;1(4):e181000. doi:10.1001/jamanetworkopen.2018.1000
Abstract Full Text pdf link PDF

HEALTH POLICY

Promoting Inclusion in Academic Medicine

JAMA Netw Open. 2018;1(4):e181010. doi:10.1001/jamanetworkopen.2018.1010
Abstract Full Text pdf link PDF

ONCOLOGY

Systemic Effects of Radiotherapy in Ductal Carcinoma In Situ

JAMA Netw Open. 2018;1(4):e181102. doi:10.1001/jamanetworkopen.2018.1102
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Primary Prevention of Perpetration and Experience of Forced Sex for South African Youth Requires Careful Attention to Risk in Context

JAMA Netw Open. 2018;1(4):e181222. doi:10.1001/jamanetworkopen.2018.1222
Abstract Full Text pdf link PDF

HEALTH POLICY

Identifying and Addressing Disparities in Survival Outcomes for Rural Patients With Cancer

JAMA Netw Open. 2018;1(4):e181243. doi:10.1001/jamanetworkopen.2018.1243
Abstract Full Text pdf link PDF

CARDIOLOGY

Drawing the Line on Prophylactic Aortic Replacement: Primum Non Nocere

JAMA Netw Open. 2018;1(4):e181289. doi:10.1001/jamanetworkopen.2018.1289
Abstract Full Text pdf link PDF

HEALTH POLICY

Medicaid Expansion and In-Hospital Cardiovascular Mortality: Failure or Unrealistic Expectations?

JAMA Netw Open. 2018;1(4):e181303. doi:10.1001/jamanetworkopen.2018.1303
Abstract Full Text pdf link PDF

HEALTH INFORMATICS

Machine Learning for Prediction in Electronic Health Data

JAMA Netw Open. 2018;1(4):e181404. doi:10.1001/jamanetworkopen.2018.1404
Abstract Full Text pdf link PDF

GASTROENTEROLOGY AND HEPATOLOGY

Human Papillomavirus Status and Esophageal Adenocarcinoma: Worth a Closer Look?

JAMA Netw Open. 2018;1(4):e181415. doi:10.1001/jamanetworkopen.2018.1415
Abstract Full Text pdf link PDF

PEDIATRICS

Paying Attention to Attention-Deficit/Hyperactivity Disorder

JAMA Netw Open. 2018;1(4):e181504. doi:10.1001/jamanetworkopen.2018.1504
Abstract Full Text pdf link PDF

HEALTH INFORMATICS

Subject Matter Knowledge in the Age of Big Data and Machine Learning

JAMA Netw Open. 2018;1(4):e181568. doi:10.1001/jamanetworkopen.2018.1568
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Rotavirus Vaccines in China: Improvement Still Required

JAMA Netw Open. 2018;1(4):e181579. doi:10.1001/jamanetworkopen.2018.1579
Abstract Full Text pdf link PDF

GLOBAL HEALTH

Prevalence of Substandard and Falsified Essential Medicines: Still an Incomplete Picture

JAMA Netw Open. 2018;1(4):e181685. doi:10.1001/jamanetworkopen.2018.1685
Abstract Full Text pdf link PDF
open access Correction

Error in Figure

JAMA Netw Open. 2018;1(4):e182583. doi:10.1001/jamanetworkopen.2018.2583
Abstract Full Text pdf link PDF
open access JAMA Network Open Masthead

JAMA Network Open

JAMA Netw Open. 2018;1(4):e181517. doi:10.1001/jamanetworkopen.2018.1517
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