This cohort study compares whether the continuation vs discontinuation of statins from advanced chronic kidney disease into the dialysis therapy period is associated with improved all-cause mortality and cardiovascular mortality in US veterans.
This survey study reviews the findings of the attitudes, perceptions, and experiences of clinical trials among clinical trial participants and nonparticipants in 68 countries.
This cross-sectional study uses a simulated patient experience to evaluate the current state of medical records request processes of US hospitals in terms of compliance with federal and state regulations and ease of patient access.
This cohort study analyzes Medicare claims linked with Surveillance, Epidemiology, and End Results (SEER) program data to assess hospitalization risk and survival among US patients receiving carboplatin-paclitaxel or carboplatin-pemetrexed for treatment of metastatic, nonsquamous, non–small cell lung cancer.
This cohort study examines the variation between California hospitals in mortality and readmission after cancer surgical procedures.
This cross-sectional study examines rates of coverage and utilization management policies for nonpharmacologic treatments for chronic, noncancer low back pain among 45 Medicaid, Medicare Advantage, and commercial 2017 health insurance plans from 16 US states.
This randomized clinical trial examines whether an online, collaborative connected-health model results in equivalent clinical improvements compared with in-person care among US adults with psoriasis.
This diagnostic study investigates whether nuclear ZEB2 expression in colorectal cancer is associated with early recurrence and reduced survival in 2 independent patient cohorts.
This cross-sectional study uses death records from the US National Center for Health Statistics to investigate the association between cancer death rates and county-level median household income and identifies potential mediating factors of this association.
This cohort study of patients in China investigates whether sustained response duration of 6 months or more following treatment with conventional transarterial chemoembolization (cTACE) is a reliable surrogate end point for overall survival in patients with intermediate hepatocellular carcinoma (HCC).
This network meta-analysis of randomized clinical trials assesses which approach in colorectal surgery (mechanical bowel preparation with and without oral antibiotics) is associated with the lowest rate of surgical site infections.
This cohort study of US infants receiving postnatal life support at 22 to 25 weeks’ gestation examines whether exposure to antenatal steroids is associated with survival to hospital discharge and survival without major morbidities.
This prognostic study develops and validates a nomogram to assess the probability of survival at 3, 6, and 12 months in patients from Taiwan with metastatic lung cancer who were referred for radiotherapy to treat osseous metastases.
This cohort study examines the outcomes of children transferred to high-capability hospitals for treatment of abdominal pain and appendicitis.
This quality improvement study examines trends across adulterated dietary supplements, containing unapproved ingredients, associated with US Food and Drug Administration (FDA) warnings.
This qualitative study examines the use and barriers to use of audit-and-feedback programs that use direct observation to assess hand hygiene compliance in acute care hospitals.
This cluster randomized clinical trial compares clinical decision support with vs without practice facilitation to improve treatment of chronic kidney disease in primary care as measured by annualized loss of estimated glomerular filtration rate.
This diagnostic study compares a rules-based natural language processing (NLP) model with a machine learning (ML) model to detect bleeding events among patients in an intensive care unit (ICU) using clinical notes.
This systematic review and meta-analysis of 17 randomized clinical trials including 3161 patients examines the association of efficacy and tolerability of cannabinoids with spasticity, pain, and bladder dysfunction in patients with multiple sclerosis (MS).
This cohort study measures physician-level use rates of 4 low-value screening tests in primary care—repeated dual-energy x-ray absorptiometry (DXA) scans, electrocardiograms (ECGs), Papanicolaou (Pap) tests, and chest radiographs—to investigate the characteristics of primary care physicians who frequently order low-value care.
This cross-sectional study investigates the association between hospital-level 30-day risk-standardized mortality rates and 30-day risk-standardized payments for acute myocardial infarction (MI), heart failure, and pneumonia among Medicare fee-for-service beneficiaries.
This case-control study examines factors associated with higher emergency department (ED) use among US patients with vs without mental health diagnoses.
This survey study examines the perceptions of risk from and use of pod-based electronic cigarettes (e-cigarettes) among adolescents and young adults.
This register-based case-control and cohort study estimates the risk of thyroxine-treated autoimmune thyroid disease among Swedish patients with rheumatoid arthritis at different time points before and after the diagnosis of rheumatoid arthritis.
This population-based cohort study uses data from the Framingham Heart Study offspring cohort to study the interaction between the apolipoprotein E genotype and chronic low-grade inflammation and its association with the incidence of Alzheimer disease.
This study assesses the association between cardiorespiratory fitness and long-term mortality in adults undergoing exercise treadmill testing.
This secondary analysis of the ASSIP randomized clinical trial compares the cost-effectiveness of a brief novel therapy vs usual care for preventing repeat suicide attempts among patients in Switzerland who had previously attempted suicide.
This cross-sectional study uses data from the National Hospital Ambulatory Medical Care Survey emergency department (ED) subsample to characterize ED visits that risk denial of coverage by health insurers under retrospective diagnosis-based policies.
This cohort study uses data from the National Surgical Quality Improvement Project and a nationally representative sample of Medicare beneficiaries to examine how often after surgical evacuation nontraumatic subdural hematoma reaccumulates and necessitates repeated operation among older US adults.
This case-control study assesses the association of prior-season influenza vaccination with vaccine effectiveness by different vaccine types and influenza types and subtypes among US children aged 2 to 17 years.
This systematic review and meta-analysis examines factors associated with focused psychotropic medication review and medication optimization.
This cross-sectional study examines Healthcare Cost and Utilization Project National Inpatient Sample data from 2003 to 2015 to identify the frequency, outcomes, and cost of hospitalizations associated with amphetamine use in the United States.
This nested case-control study analyzes 3 independent cohorts to determine whether the 3-gene tuberculosis (TB) score can be a diagnostic tool throughout the course of TB disease and posttreatment residual inflammation by distinguishing individuals who progress to active TB vs those who do not, those with vs without active TB, and those with slower treatment response.
This cross-sectional study of community-dwelling New Zealanders 65 years and older examines the association between loneliness and psychosocial variables in centenarians compared with elderly people.
This randomized clinical trial evaluates the effect of an intervention that aims to prevent young child overweight and obesity and to improve health in the US-Affiliated Pacific region via the Children’s Healthy Living Program.
This cohort study develops 2 clinical risk scores based on variables available at clinical presentation to estimate the risk of carbapenem resistance or extensive β-lactam resistance among hospitalized adult patients with Pseudomonas aeruginosa infections.
This cohort study examines the proportion of injured workers’ compensation claimants who filled an opioid prescription beyond 90 days from their time of injury and the factors associated with persistent opioid use.
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