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November 2018 - May 2018

Decade

Year

Issue

October 2018, Vol 1, No. 6

open access Original Investigation

NEPHROLOGY

Association of Continuation of Statin Therapy Initiated Before Transition to Chronic Dialysis Therapy With Mortality After Dialysis Initiation

This cohort study compares whether the continuation vs discontinuation of statins from advanced chronic kidney disease into the dialysis therapy period is associated with improved all-cause mortality and cardiovascular mortality in US veterans.

JAMA Netw Open. 2018;1(6):e182311. doi:10.1001/jamanetworkopen.2018.2311
Abstract Full Text pdf link PDF

GLOBAL HEALTH

Global Public Attitudes About Clinical Research and Patient Experiences With Clinical Trials

This survey study reviews the findings of the attitudes, perceptions, and experiences of clinical trials among clinical trial participants and nonparticipants in 68 countries.

JAMA Netw Open. 2018;1(6):e182969. doi:10.1001/jamanetworkopen.2018.2969
Abstract Full Text pdf link PDF

HEALTH INFORMATICS

Assessment of US Hospital Compliance With Regulations for Patients’ Requests for Medical Records

This cross-sectional study uses a simulated patient experience to evaluate the current state of medical records request processes of US hospitals in terms of compliance with federal and state regulations and ease of patient access.

JAMA Netw Open. 2018;1(6):e183014. doi:10.1001/jamanetworkopen.2018.3014
Abstract Full Text pdf link PDF

ONCOLOGY

Hospitalization and Survival of Medicare Patients Treated With Carboplatin Plus Paclitaxel or Pemetrexed for Metastatic, Nonsquamous, Non–Small Cell Lung Cancer

This cohort study analyzes Medicare claims linked with Surveillance, Epidemiology, and End Results (SEER) program data to assess hospitalization risk and survival among US patients receiving carboplatin-paclitaxel or carboplatin-pemetrexed for treatment of metastatic, nonsquamous, non–small cell lung cancer.

JAMA Netw Open. 2018;1(6):e183023. doi:10.1001/jamanetworkopen.2018.3023
Abstract Full Text pdf link PDF

HEALTH POLICY

Assessment of Between-Hospital Variation in Readmission and Mortality After Cancer Surgical Procedures

This cohort study examines the variation between California hospitals in mortality and readmission after cancer surgical procedures.

JAMA Netw Open. 2018;1(6):e183038. doi:10.1001/jamanetworkopen.2018.3038
Abstract Full Text pdf link PDF

HEALTH POLICY

Coverage of Nonpharmacologic Treatments for Low Back Pain Among US Public and Private Insurers

This cross-sectional study examines rates of coverage and utilization management policies for nonpharmacologic treatments for chronic, noncancer low back pain among 45 Medicaid, Medicare Advantage, and commercial 2017 health insurance plans from 16 US states.

JAMA Netw Open. 2018;1(6):e183044. doi:10.1001/jamanetworkopen.2018.3044
Abstract Full Text pdf link PDF

DERMATOLOGY

Effectiveness of Online vs In-Person Care for Adults With PsoriasisA Randomized Clinical Trial

This randomized clinical trial examines whether an online, collaborative connected-health model results in equivalent clinical improvements compared with in-person care among US adults with psoriasis.

JAMA Netw Open. 2018;1(6):e183062. doi:10.1001/jamanetworkopen.2018.3062
Abstract Full Text pdf link PDF

ONCOLOGY

Assessment of Nuclear ZEB2 as a Biomarker for Colorectal Cancer Outcome and TNM Risk Stratification

This diagnostic study investigates whether nuclear ZEB2 expression in colorectal cancer is associated with early recurrence and reduced survival in 2 independent patient cohorts.

JAMA Netw Open. 2018;1(6):e183115. doi:10.1001/jamanetworkopen.2018.3115
Abstract Full Text pdf link PDF

ONCOLOGY

Factors Associated With Cancer Disparities Among Low-, Medium-, and High-Income US Counties

This cross-sectional study uses death records from the US National Center for Health Statistics to investigate the association between cancer death rates and county-level median household income and identifies potential mediating factors of this association.

JAMA Netw Open. 2018;1(6):e183146. doi:10.1001/jamanetworkopen.2018.3146
Abstract Full Text pdf link PDF

ONCOLOGY

Association of Sustained Response Duration With Survival After Conventional Transarterial Chemoembolization in Patients With Hepatocellular Carcinoma

This cohort study of patients in China investigates whether sustained response duration of 6 months or more following treatment with conventional transarterial chemoembolization (cTACE) is a reliable surrogate end point for overall survival in patients with intermediate hepatocellular carcinoma (HCC).

JAMA Netw Open. 2018;1(6):e183213. doi:10.1001/jamanetworkopen.2018.3213
Abstract Full Text pdf link PDF

SURGERY

Association of Mechanical Bowel Preparation and Oral Antibiotics Before Elective Colorectal Surgery With Surgical Site InfectionA Network Meta-analysis

This network meta-analysis of randomized clinical trials assesses which approach in colorectal surgery (mechanical bowel preparation with and without oral antibiotics) is associated with the lowest rate of surgical site infections.

JAMA Netw Open. 2018;1(6):e183226. doi:10.1001/jamanetworkopen.2018.3226
Abstract Full Text pdf link PDF

PEDIATRICS

Association of Antenatal Steroid Exposure With Survival Among Infants Receiving Postnatal Life Support at 22 to 25 Weeks’ Gestation

This cohort study of US infants receiving postnatal life support at 22 to 25 weeks’ gestation examines whether exposure to antenatal steroids is associated with survival to hospital discharge and survival without major morbidities.

JAMA Netw Open. 2018;1(6):e183235. doi:10.1001/jamanetworkopen.2018.3235
Abstract Full Text pdf link PDF

ONCOLOGY

Development and Validation of a Nomogram for Assessing Survival in Patients With Metastatic Lung Cancer Referred for Radiotherapy for Bone Metastases

This prognostic study develops and validates a nomogram to assess the probability of survival at 3, 6, and 12 months in patients from Taiwan with metastatic lung cancer who were referred for radiotherapy to treat osseous metastases.

JAMA Netw Open. 2018;1(6):e183242. doi:10.1001/jamanetworkopen.2018.3242
Abstract Full Text pdf link PDF

PEDIATRICS

Outcomes of Hospital Transfers for Pediatric Abdominal Pain and Appendicitis

This cohort study examines the outcomes of children transferred to high-capability hospitals for treatment of abdominal pain and appendicitis.

JAMA Netw Open. 2018;1(6):e183249. doi:10.1001/jamanetworkopen.2018.3249
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Unapproved Pharmaceutical Ingredients Included in Dietary Supplements Associated With US Food and Drug Administration Warnings

This quality improvement study examines trends across adulterated dietary supplements, containing unapproved ingredients, associated with US Food and Drug Administration (FDA) warnings.

JAMA Netw Open. 2018;1(6):e183337. doi:10.1001/jamanetworkopen.2018.3337
Abstract Full Text pdf link PDF

HEALTH POLICY

Evaluation of Barriers to Audit-and-Feedback Programs That Used Direct Observation of Hand Hygiene ComplianceA Qualitative Study

This qualitative study examines the use and barriers to use of audit-and-feedback programs that use direct observation to assess hand hygiene compliance in acute care hospitals.

JAMA Netw Open. 2018;1(6):e183344. doi:10.1001/jamanetworkopen.2018.3344
Abstract Full Text pdf link PDF

NEPHROLOGY

Effect of 2 Clinical Decision Support Strategies on Chronic Kidney Disease Outcomes in Primary CareA Cluster Randomized Trial

This cluster randomized clinical trial compares clinical decision support with vs without practice facilitation to improve treatment of chronic kidney disease in primary care as measured by annualized loss of estimated glomerular filtration rate.

JAMA Netw Open. 2018;1(6):e183377. doi:10.1001/jamanetworkopen.2018.3377
Abstract Full Text pdf link PDF

HEALTH INFORMATICS

Comparison of 2 Natural Language Processing Methods for Identification of Bleeding Among Critically Ill Patients

This diagnostic study compares a rules-based natural language processing (NLP) model with a machine learning (ML) model to detect bleeding events among patients in an intensive care unit (ICU) using clinical notes.

JAMA Netw Open. 2018;1(6):e183451. doi:10.1001/jamanetworkopen.2018.3451
Abstract Full Text pdf link PDF

NEUROLOGY

Assessment of Efficacy and Tolerability of Medicinal Cannabinoids in Patients With Multiple SclerosisA Systematic Review and Meta-analysis

This systematic review and meta-analysis of 17 randomized clinical trials including 3161 patients examines the association of efficacy and tolerability of cannabinoids with spasticity, pain, and bladder dysfunction in patients with multiple sclerosis (MS).

JAMA Netw Open. 2018;1(6):e183485. doi:10.1001/jamanetworkopen.2018.3485
Abstract Full Text pdf link PDF

HEALTH POLICY

Physician Characteristics Associated With Ordering 4 Low-Value Screening Tests in Primary Care

This cohort study measures physician-level use rates of 4 low-value screening tests in primary care—repeated dual-energy x-ray absorptiometry (DXA) scans, electrocardiograms (ECGs), Papanicolaou (Pap) tests, and chest radiographs—to investigate the characteristics of primary care physicians who frequently order low-value care.

JAMA Netw Open. 2018;1(6):e183506. doi:10.1001/jamanetworkopen.2018.3506
Abstract Full Text pdf link PDF

HEALTH POLICY

Variation in and Hospital Characteristics Associated With the Value of Care for Medicare Beneficiaries With Acute Myocardial Infarction, Heart Failure, and Pneumonia

This cross-sectional study investigates the association between hospital-level 30-day risk-standardized mortality rates and 30-day risk-standardized payments for acute myocardial infarction (MI), heart failure, and pneumonia among Medicare fee-for-service beneficiaries.

JAMA Netw Open. 2018;1(6):e183519. doi:10.1001/jamanetworkopen.2018.3519
Abstract Full Text pdf link PDF

EMERGENCY MEDICINE

Factors Associated With Emergency Department Use by Patients With and Without Mental Health Diagnoses

This case-control study examines factors associated with higher emergency department (ED) use among US patients with vs without mental health diagnoses.

JAMA Netw Open. 2018;1(6):e183528. doi:10.1001/jamanetworkopen.2018.3528
Abstract Full Text pdf link PDF

SUBSTANCE USE AND ADDICTION

Adolescents’ and Young Adults’ Use and Perceptions of Pod-Based Electronic Cigarettes

This survey study examines the perceptions of risk from and use of pod-based electronic cigarettes (e-cigarettes) among adolescents and young adults.

JAMA Netw Open. 2018;1(6):e183535. doi:10.1001/jamanetworkopen.2018.3535
Abstract Full Text pdf link PDF

RHEUMATOLOGY

Risk of Thyroxine-Treated Autoimmune Thyroid Disease Associated With Disease Onset in Patients With Rheumatoid Arthritis

This register-based case-control and cohort study estimates the risk of thyroxine-treated autoimmune thyroid disease among Swedish patients with rheumatoid arthritis at different time points before and after the diagnosis of rheumatoid arthritis.

JAMA Netw Open. 2018;1(6):e183567. doi:10.1001/jamanetworkopen.2018.3567
Abstract Full Text pdf link PDF

GERIATRICS

Association of Chronic Low-grade Inflammation With Risk of Alzheimer Disease in ApoE4 Carriers

This population-based cohort study uses data from the Framingham Heart Study offspring cohort to study the interaction between the apolipoprotein E genotype and chronic low-grade inflammation and its association with the incidence of Alzheimer disease.

JAMA Netw Open. 2018;1(6):e183597. doi:10.1001/jamanetworkopen.2018.3597
Abstract Full Text pdf link PDF

CARDIOLOGY

Association of Cardiorespiratory Fitness With Long-term Mortality Among Adults Undergoing Exercise Treadmill Testing

This study assesses the association between cardiorespiratory fitness and long-term mortality in adults undergoing exercise treadmill testing.

JAMA Netw Open. 2018;1(6):e183605. doi:10.1001/jamanetworkopen.2018.3605
Abstract Full Text pdf link PDF

PSYCHIATRY

Cost-effectiveness of a Brief Structured Intervention Program Aimed at Preventing Repeat Suicide Attempts Among Those Who Previously Attempted SuicideA Secondary Analysis of the ASSIP Randomized Clinical Trial

This secondary analysis of the ASSIP randomized clinical trial compares the cost-effectiveness of a brief novel therapy vs usual care for preventing repeat suicide attempts among patients in Switzerland who had previously attempted suicide.

JAMA Netw Open. 2018;1(6):e183680. doi:10.1001/jamanetworkopen.2018.3680
Abstract Full Text pdf link PDF

HEALTH POLICY

Analysis of a Commercial Insurance Policy to Deny Coverage for Emergency Department Visits With Nonemergent Diagnoses

This cross-sectional study uses data from the National Hospital Ambulatory Medical Care Survey emergency department (ED) subsample to characterize ED visits that risk denial of coverage by health insurers under retrospective diagnosis-based policies.

JAMA Netw Open. 2018;1(6):e183731. doi:10.1001/jamanetworkopen.2018.3731
Abstract Full Text pdf link PDF

SURGERY

Rates of Repeated Operation for Isolated Subdural Hematoma Among Older Adults

This cohort study uses data from the National Surgical Quality Improvement Project and a nationally representative sample of Medicare beneficiaries to examine how often after surgical evacuation nontraumatic subdural hematoma reaccumulates and necessitates repeated operation among older US adults.

JAMA Netw Open. 2018;1(6):e183737. doi:10.1001/jamanetworkopen.2018.3737
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

Association of Prior Vaccination With Influenza Vaccine Effectiveness in Children Receiving Live Attenuated or Inactivated Vaccine

This case-control study assesses the association of prior-season influenza vaccination with vaccine effectiveness by different vaccine types and influenza types and subtypes among US children aged 2 to 17 years.

JAMA Netw Open. 2018;1(6):e183742. doi:10.1001/jamanetworkopen.2018.3742
Abstract Full Text pdf link PDF

PSYCHIATRY

Association of Focused Medication Review With Optimization of Psychotropic Drug PrescribingA Systematic Review and Meta-analysis

This systematic review and meta-analysis examines factors associated with focused psychotropic medication review and medication optimization.

JAMA Netw Open. 2018;1(6):e183750. doi:10.1001/jamanetworkopen.2018.3750
Abstract Full Text pdf link PDF

SUBSTANCE USE AND ADDICTION

Evaluation of Amphetamine-Related Hospitalizations and Associated Clinical Outcomes and Costs in the United States

This cross-sectional study examines Healthcare Cost and Utilization Project National Inpatient Sample data from 2003 to 2015 to identify the frequency, outcomes, and cost of hospitalizations associated with amphetamine use in the United States.

JAMA Netw Open. 2018;1(6):e183758. doi:10.1001/jamanetworkopen.2018.3758
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

Assessment of Validity of a Blood-Based 3-Gene Signature Score for Progression and Diagnosis of Tuberculosis, Disease Severity, and Treatment Response

This nested case-control study analyzes 3 independent cohorts to determine whether the 3-gene tuberculosis (TB) score can be a diagnostic tool throughout the course of TB disease and posttreatment residual inflammation by distinguishing individuals who progress to active TB vs those who do not, those with vs without active TB, and those with slower treatment response.

JAMA Netw Open. 2018;1(6):e183779. doi:10.1001/jamanetworkopen.2018.3779
Abstract Full Text pdf link PDF

GERIATRICS

Comparison of Psychosocial Variables Associated With Loneliness in Centenarian vs Elderly Populations in New Zealand

This cross-sectional study of community-dwelling New Zealanders 65 years and older examines the association between loneliness and psychosocial variables in centenarians compared with elderly people.

JAMA Netw Open. 2018;1(6):e183880. doi:10.1001/jamanetworkopen.2018.3880
Abstract Full Text pdf link PDF

GLOBAL HEALTH

Effect of the Children’s Healthy Living Program on Young Child Overweight, Obesity, and Acanthosis Nigricans in the US-Affiliated Pacific RegionA Randomized Clinical Trial

This randomized clinical trial evaluates the effect of an intervention that aims to prevent young child overweight and obesity and to improve health in the US-Affiliated Pacific region via the Children’s Healthy Living Program.

JAMA Netw Open. 2018;1(6):e183896. doi:10.1001/jamanetworkopen.2018.3896
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

Development and Assessment of Risk Scores for Carbapenem and Extensive β-Lactam Resistance Among Adult Hospitalized Patients With Pseudomonas aeruginosa Infection

This cohort study develops 2 clinical risk scores based on variables available at clinical presentation to estimate the risk of carbapenem resistance or extensive β-lactam resistance among hospitalized adult patients with Pseudomonas aeruginosa infections.

JAMA Netw Open. 2018;1(6):e183927. doi:10.1001/jamanetworkopen.2018.3927
Abstract Full Text pdf link PDF

OCCUPATIONAL HEALTH

Factors Associated With Persistent Opioid Use Among Injured Workers’ Compensation Claimants

This cohort study examines the proportion of injured workers’ compensation claimants who filled an opioid prescription beyond 90 days from their time of injury and the factors associated with persistent opioid use.

JAMA Netw Open. 2018;1(6):e184050. doi:10.1001/jamanetworkopen.2018.4050
Abstract Full Text pdf link PDF
open access Invited Commentary

NEPHROLOGY

Statins at Dialysis Transition—Supportive but Not Sufficient

JAMA Netw Open. 2018;1(6):e182411. doi:10.1001/jamanetworkopen.2018.2411
Abstract Full Text pdf link PDF

HEALTH POLICY

Variation Across the Continuum of Surgical Oncology Care

JAMA Netw Open. 2018;1(6):e183035. doi:10.1001/jamanetworkopen.2018.3035
Abstract Full Text pdf link PDF

HEALTH POLICY

Insurer Coverage of Nonpharmacological Treatments for Low Back Pain—Time for a Change

JAMA Netw Open. 2018;1(6):e183037. doi:10.1001/jamanetworkopen.2018.3037
Abstract Full Text pdf link PDF

ONCOLOGY

Can ZEB2 Be Used as a Molecular Marker for Risk Stratification of Patients With Colorectal Cancer?

JAMA Netw Open. 2018;1(6):e183133. doi:10.1001/jamanetworkopen.2018.3133
Abstract Full Text pdf link PDF

ONCOLOGY

Evaluating the Potential Benefits of Using Sustained Response as a Prognostic Factor in Intermediate Hepatocellular Carcinoma Following Treatment With Conventional Chemoembolization

JAMA Netw Open. 2018;1(6):e183209. doi:10.1001/jamanetworkopen.2018.3209
Abstract Full Text pdf link PDF

SURGERY

When Will the Surgical Community Acknowledge the Evidence Regarding Prophylaxis With Oral Antibiotics for Scheduled Colorectal Operations?

JAMA Netw Open. 2018;1(6):e183257. doi:10.1001/jamanetworkopen.2018.3257
Abstract Full Text pdf link PDF

PUBLIC HEALTH

The FDA and Adulterated Supplements—Dereliction of Duty

JAMA Netw Open. 2018;1(6):e183329. doi:10.1001/jamanetworkopen.2018.3329
Abstract Full Text pdf link PDF

NEPHROLOGY

The Promise and Pitfalls of Pragmatic Clinical Trials for Improving Health Care Quality

JAMA Netw Open. 2018;1(6):e183376. doi:10.1001/jamanetworkopen.2018.3376
Abstract Full Text pdf link PDF

HEALTH POLICY

Time to Implement Immediate Personalized Feedback and Individualized Action Planning for Hand Hygiene

JAMA Netw Open. 2018;1(6):e183422. doi:10.1001/jamanetworkopen.2018.3422
Abstract Full Text pdf link PDF

NEUROLOGY

Cannabinoids for Symptoms of Multiple SclerosisBenefits to Patients Still Unclear

JAMA Netw Open. 2018;1(6):e183484. doi:10.1001/jamanetworkopen.2018.3484
Abstract Full Text pdf link PDF

HEALTH POLICY

Measuring and Improving the Value of Hospital Care

JAMA Netw Open. 2018;1(6):e183517. doi:10.1001/jamanetworkopen.2018.3517
Abstract Full Text pdf link PDF

SUBSTANCE USE AND ADDICTION

Pod Mod Electronic Cigarettes—An Emerging Threat to Public Health

JAMA Netw Open. 2018;1(6):e183518. doi:10.1001/jamanetworkopen.2018.3518
Abstract Full Text pdf link PDF

HEALTH POLICY

Policies That Limit Emergency Department Visits and Reimbursements Undermine the Emergency Care SystemInstead, Let’s Optimize It

JAMA Netw Open. 2018;1(6):e183728. doi:10.1001/jamanetworkopen.2018.3728
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

Repeated Vaccination May Protect Children From Influenza Infection

JAMA Netw Open. 2018;1(6):e183730. doi:10.1001/jamanetworkopen.2018.3730
Abstract Full Text pdf link PDF

PSYCHIATRY

Psychotropic Medication ReviewQuo Vadit?

JAMA Netw Open. 2018;1(6):e183868. doi:10.1001/jamanetworkopen.2018.3868
Abstract Full Text pdf link PDF
open access Correction

Error in Title and Figure

JAMA Netw Open. 2018;1(6):e184055. doi:10.1001/jamanetworkopen.2018.4055
Abstract Full Text pdf link PDF

Error in Byline Order

JAMA Netw Open. 2018;1(6):e184304. doi:10.1001/jamanetworkopen.2018.4304
Abstract Full Text pdf link PDF

Error in Key Points

JAMA Netw Open. 2018;1(6):e184644. doi:10.1001/jamanetworkopen.2018.4644
Abstract Full Text pdf link PDF

Error in Text

JAMA Netw Open. 2018;1(6):e185010. doi:10.1001/jamanetworkopen.2018.5010
Abstract Full Text pdf link PDF
open access JAMA Network Open Masthead

JAMA Network Open

JAMA Netw Open. 2018;1(6):e184013. doi:10.1001/jamanetworkopen.2018.4013
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