This cross-sectional study examines whether social risk factors, including race/ethnicity, insurance status, and neighborhood income, are associated with higher rates of surgical site infection after colectomy or abdominal hysterectomy.
This cohort study investigates the associations between maternal red blood cell lead levels and intergenerational risk of overweight or obesity and whether adequate maternal folate status is associated with a reduction in this risk.
This cohort study of adults aged 65 years and older examines whether more fragmentated physical activity, rather than total daily activity, is associated with increased mortality risk.
This trial protocol describes a randomized clinical trial that will investigate the efficacy and safety of a novel enhanced rehabilitation program to reduce environmental barriers and improve daily activity performance and community participation among stroke survivors.
This cohort study assesses whether clinical frailty scores are associated with readmission for falls after index admission for trauma-related injury among patients aged 50 years and older.
This cross-sectional study characterizes secondary genomic alterations in patients with epithelioid hemangioendothelioma and their association with clinical outcomes.
This population-based cohort study examines associations between prenatal thyroid hormone replacement therapy exposure and risk of language impairment and parent-reported symptoms of language and communication skill deficits in offspring at 8 years of age.
This decision analytical model study uses a simulation model to evaluate the potential implications of a presumed consent policy for deceased organ donation allocation and availability in the United States.
This cross-sectional study investigates whether indoor tanning salons are disproportionately located in areas with higher concentrations of sexual-minority men, defined as gay and bisexual men, using male-male partnered households as a proxy measure.
This systematic review and meta-analysis assesses the association of rotavirus vaccination among neonates and infants with risk of intussusception for up to 2 years after vaccination overall and by type of vaccine.
This cohort study examines the association of attention-deficit/hyperactivity disorder (ADHD) with teenage pregnancy among women and girls in Sweden.
This cohort study evaluates whether restrictive housing, otherwise known as solitary confinement, during incarceration is associated with reincarceration and mortality after release.
This cohort study evaluates the progression and regression of hepatic fibrosis over time in association with the severity of nonalcoholic fatty liver disease.
This diagnostic study evaluates whether fellowship training and board certification of physicians in dermatopathology affect the diagnostic reliability of second-opinion strategies for difficult-to-diagnose cutaneous melanocytic lesions.
This randomized clinical trial assesses whether a comprehensive care coordination program reduces Medicaid expenditures by decreasing hospital and emergency department utilization among publicly insured children and youth.
This prespecified subgroup analysis of control participants in an individual participant data meta-analysis examines the association between supine vs nonsupine maternal sleeping position in the third trimester of pregnancy and infant birth weight.
This qualitative analysis using interviews with physicians determines barriers and facilitators in electronic health record inbox management and suggestions for improvement.
This study of national rates of health care–associated infections estimates the number of hospitals needed to power parallel cluster-randomized trials of interventions and evaluates how different parameters such as coefficient of variation and expected effect size are associated with the sample size estimates in practice.
This systematic review and meta-analysis examines whether the use of aspirin, heparin, and interferon in pregnant women with myeloproliferative neoplasms is associated with live birth rate and adverse maternal outcomes.
This cohort study uses Surveillance, Epidemiology, and End Results data to examine whether there is a survival benefit associated with liver transplant vs resection in pediatric patients with hepatoblastoma receiving chemotherapy.
This cross-sectional study uses data from the New York State Health Cost and Utilization Project State Inpatient Database to examine whether the reliability of American Community Survey socioeconomic status estimates improves with the use of new peer group–based strata compared with previous stratification by safety-net hospital designation.
This cross-sectional study examines clinical and radiological outcomes among patients with myelin oligodendrocyte glycoprotein (MOG) antibody (Ab) disease or aquaporin-4 (AQP4)-Ab disease after experiencing a first transverse myelitis episode.
This cohort study uses population-based administrative and clinical databases to develop and validate a score to predict early use of acute care after initiating systemic therapy for cancer.
This secondary analysis of the Systolic Blood Pressure Intervention Trial (SPRINT) investigates whether aortic stiffness, as assessed by estimated pulse wave velocity, and its response to treatment are associated with survival in individuals with hypertension.
This cohort study compares the resource utilization, clinical outcomes, and severity of injuries from a firearm vs other penetrating mechanisms among children and adolescents in the United States.
This cross-sectional study analyzes the feasibility of replicating clinical trials by examining whether the interventions, indications, inclusion and exclusion criteria, and primary end points could be ascertained from observational data from insurance claims and/or electronic health records (EHRs).
This systematic review and meta-analysis examines the association of accelerometer- and pedometer-based interventions with increases in physical activity among participants with cardiometabolic conditions.
This cohort study evaluates the short-term association of exposure to air pollution in the first trimester with thyroid function throughout pregnancy among European and US cohorts.
This decision analytical model study uses a virtual cohort of 100 000 individuals modeled from birth to age 40 years for 4 eating disorder diagnoses to examine whether increasing treatment coverage could reduce the mortality associated with eating disorders.
This population-based cohort study examines treatment patterns for stenosing tenosynovitis (trigger finger) and determines surgeon-level factors associated with adherence to evidence-based treatment.
This cross-sectional US nationwide survey study assesses the negative and positive aspects of family leave and return-to-work experiences among physician mothers to identify best practices for supporting physician parents.
This cohort study assesses whether changes in overall rates of use of diagnostic cardiovascular tests were associated with changes in high-value testing recommended by guidelines and low-value testing that is expected to provide minimal benefits among a 5% national sample of Medicare beneficiaries between 2000 and 2006.
This systematic review and meta-analysis examines the risk for serious infections, opportunistic infections, and cancers in individuals receiving interleukin inhibitor therapies for rheumatologic diseases.
This survey study examines the association of family-rated quality of end-of-life care with stopping dialysis treatment and receipt of hospice services among veterans with end-stage renal disease.
This 5-decade cohort study of a New Zealand population examines whether slow gait speed in middle age is associated with accelerated biological aging, as well as poor neurocognitive functioning in childhood and cognitive decline from childhood to middle age.
This cross-sectional study examines the association of adherence to the American Heart Association (AHA) revised Life’s Simple 7 (LS7) metrics with reduced risk of all-cause, cancer, and cardiovascular disease–related mortality and compares the revised metrics with the original LS7 metrics.
This cohort study examines racial/ethnic differences in all-cause readmission among US adults with diabetes and categorizes patient- and system-level factors associated with these differences.
This cross-sectional study uses data from the National Emergency Medical Services Information System to investigate the use of mechanical cardiopulmonary resuscitation (CPR) in the prehospital setting and determine whether patient demographics or geographical location is associated with its use.
This population-based case-control study of individuals aged 66 years and older in Ontario, Canada, examines whether angiotensin receptor blockers are associated with a higher risk of suicide than angiotensin-converting enzyme inhibitors.
This survey study estimates the national frequency and consequences of cascades of care after incidental findings using results from a national survey of US physicians.
This secondary analysis of a randomized clinical trial examines the association of a 6-month multidomain active lifestyle intervention with sarcopenia among elderly participants in Singapore.
This survey study examines whether β-amyloid deposition in the brain is associated with sleep dysfunction and cognition in elderly individuals with cognitive disorders.
This systematic review and meta-analysis examines the association between breastfeeding and maternal risk of diabetes and hypertension.
This diagnostic study determines the accuracy of an artificial intelligence algorithm in identifying melanoma in dermoscopic images of lesions taken with smartphone and digital single-lens reflex (DSLR) cameras.
This cohort study examines the associations of acquired and heritable factors associated with intergenerational differences in age at symptomatic onset of Alzheimer disease among offspring of parents with Alzheimer disease.
This qualitative study describes the professional experiences and the perceived associations with gender, race/ethnicity, sexual orientation, and gender identity of a diverse group of primary care clinicians and clinic directors in an underserved rural and agricultural region of California.
This cross-sectional study examines temporal trends and variations in the use of defibrillation testing among patients undergoing first-time implantable cardioverter-defibrillator implantation.
This cohort study evaluates data from the Nurses’ Health Study II to investigate the association of occupational exposure to disinfectants and other cleaning products with the incidence of chronic obstructive pulmonary disease (COPD) among female US registered nurses with no history of COPD at baseline.
This cohort study compares the surgical site infection rate associated with laparoscopic colon surgery vs open-approach laparoscopy.
This cohort study examines endothelial function in patients with early HIV infection at baseline and after antiretroviral therapy initiation.
This systematic review and meta-analysis assesses whether concurrent chemoradiotherapy is associated with improvement in survival outcomes for patients with locoregionally advanced nasopharyngeal carcinoma.
This cross-sectional study uses surveys to describe and compare pneumococcal nasopharyngeal carriage and density by vaginal vs cesarean delivery in young Fijian infants.
This cohort study examines the association of pediatric inpatient socioeconomic status with the hospital’s efficiency and financial balance in France.
This cohort study develops and assesses electronic surveillance definitions for nonventilator hospital-acquired pneumonia using clinical data routinely recorded in electronic health records.
This case-control study examines gender differences in authorship of invited commentaries published in medical journals from 2013 to 2017, controlling for field of expertise, seniority, and publication metrics.
This randomized clinical trial compares the long-term effects of weight loss via severe vs moderate energy restriction on lean mass and other aspects of body composition among postmenopausal women with obesity.
This cohort study uses data from the Population Assessment of Tobacco and Health (PATH) Study to examine whether first use of flavored tobacco products is associated with subsequent tobacco use among US youth and adults.
This protocol describes a randomized clinical noninferiority trial to determine whether cognitive behavioral therapy delivered online as part of a stepped care model is noninferior to, and cost-effective compared with, face-to-face cognitive behavioral therapy for pediatric obsessive-compulsive disorder (OCD).
This quality improvement study examines the association of a multimodal educational intervention for primary care physicians (PCPs) with prescriptions of buprenorphine for treatment of patients with opioid use disorder.
This cluster randomized trial investigates the effect of frequency of changing hand hygiene reminder signs on hand hygiene adherence among health care workers.
This diagnostic study evaluates whether RNA genetic testing (RGT) is associated with an improvement in the diagnostic outcome of DNA genetic testing (DGT) and in the delivery of personalized cancer risk management for patients with hereditary cancer predisposition.
This cohort study investigates the association of the apolipoprotein E (APOE) ɛ4 allele, education levels, and sex with tau deposition and tau-mediated metabolic dysfunction in older adults.
This economic evaluation uses computer-simulated patients to examine the cost-effectiveness of short (1 hour) vs prolonged (≥6 hours) medical observation for biphasic anaphylaxis after an episode of resolved anaphylaxis.
This cohort study evaluates the feasibility and utility of incorporating comparative gene expression information into the precision medicine framework for difficult-to-treat pediatric and young adult patients with cancer.
This cohort study uses the Patient-Reported Outcome Measurement Information System to assess the association between the functional medicine model of care and patient-reported health-related quality of life among adults.
This cohort study assesses the association of metabolically healthy overweight phenotype with the risk of glucose level abnormality and high blood pressure in Chinese adults.
This cohort study assesses associations between sexual activity, the oral presence of human papillomavirus (HPV), and HPV vaccination among sexually active female adolescents vaccinated against 4 HPV types.
This qualitative study analyzes submissions to a popular machine learning for health workshop to assess the current state of health research, including areas of methodologic and clinical focus, limitations, and underexplored areas.
This cross-sectional study of 65 infants in Puerto Rico examines the associations of exposure to maternal Zika virus and Hurricane Maria with infant cognitive scores.
This cohort study examines the association between results of universal and selective screening for suicide risk in a pediatric emergency department using the Ask Suicide-Screening Questions (ASQ) instrument and subsequent suicide-related outcomes.
This cohort study of the Women’s Health Initiative (WHI) assesses the associations of physical activity and sedentary behavior with fracture incidence among postmenopausal women.
This cross-sectional study reports revenues and estimated profits from the 340B drug discount program that hospitals collect from Medicare and Medicare beneficiaries for outpatient clinic administration of prescription drugs covered under Medicare Part B.
This cohort study examines the 5-year incidence of community-acquired and health care facility–associated Clostridioides difficile infection among patients in US community hospitals.
This randomized clinical trial evaluates the effect of treatment with a combination of L-citrulline and metformin on the motor function of ambulant boys with Duchenne muscular dystrophy.
This systematic review and meta-analysis evaluates whether caregiver-targeted interventions are associated with changes in the use of child restraint systems in motor vehicles.
This cohort study examines the association of race/ethnicity with discharge disposition and 90-day hospital readmission overall and stratified by age among patients who have undergone total knee arthroplasty.
This cohort study of patients with atrial fibrillation who underwent left atrial appendage closure with an implanted device evaluates postprocedural mortality rates and rates of readmission and ischemic stroke.
This cohort study describes the development and validation of a targeted next-generation sequencing gene panel to identify monogenic disease-causing mutations in children with unclassified neuroinflammation.
This cohort study evaluates variation in patient outcomes and costs for primary hip and knee replacement across health areas in England and identifies whether patient, surgical, or hospital factors are associated with such variation.
This cross-sectional epidemiological study of a random community sample of adolescents and young adults in Dresden, Germany, examines the prevalence and timing of suicidal ideation, planning, and attempt.
This cohort study develops, validates, and compares machine learning algorithms that use structured electronic health record data before a clinic visit to predict mortality among patients with cancer.
This cross-sectional study estimates the difference in Medicaid enrollment associated with Indiana’s expansion of Medicaid using a Section 1115 waiver.
This cross-sectional study describes the characteristics of abbreviated new drug applications approved by the US Food and Drug Administration, focusing on those with limited generic competition or with history of shortages.
This case series evaluates the direct bilirubin levels in the first days after birth among neonates who were subsequently diagnosed with biliary atresia.
This cohort study examines the association between use of 5α-reductase inhibitors and prostate cancer mortality among US Medicare beneficiaries.
This cross-sectional study examines Google searches for cannabidiol (CBD) in the United States to gauge public interest in the use of CBD.
This cross-sectional study uses Medical Expenditure Panel Survey data to examine the association of the length of time a first-generation immigrant has spent in the United States with the likelihood of opioid use.
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