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February 2021 - May 2018

Decade

Year

Issue

November 2019, Vol 2, No. 11

open access Original Investigation

PEDIATRICS

Association of Punitive and Reporting State Policies Related to Substance Use in Pregnancy With Rates of Neonatal Abstinence Syndrome

This cross-sectional study examines the association of state-level punitive or reporting policies related to substance use during pregnancy with rates of neonatal abstinence syndrome.

JAMA Netw Open. 2019;2(11):e1914078. doi:10.1001/jamanetworkopen.2019.14078
Abstract Full Text pdf link PDF

PSYCHIATRY

Trends in the Prevalence and Incidence of Attention-Deficit/Hyperactivity Disorder Among Adults and Children of Different Racial and Ethnic Groups

This cohort study examines trends, including associated demographic characteristics, psychiatric diagnoses, and negative outcomes, in the prevalence and incidence of attention-deficit/hyperactivity disorder (ADHD) diagnosis among 7 racial/ethnic groups in the United States during a 10-year period.

JAMA Netw Open. 2019;2(11):e1914344. doi:10.1001/jamanetworkopen.2019.14344
Abstract Full Text pdf link PDF

DIABETES AND ENDOCRINOLOGY

Association Between Switching to a High-Deductible Health Plan and Discontinuation of Type 2 Diabetes Treatment

This matched cohort study evaluates the association between switching from a non–high deductible health plan to a high-deductible health plan and discontinuation of antihyperglycemic medication among adults with type 2 diabetes.

JAMA Netw Open. 2019;2(11):e1914372. doi:10.1001/jamanetworkopen.2019.14372
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

Trends in HIV Prevention, Treatment, and Incidence in a Hyperendemic Area of KwaZulu-Natal, South Africa

This community-based cohort study examines trends in coverage of HIV prevention and treatment programs and HIV incidence among adults in the hyperendemic area of KwaZulu-Natal, South Africa.

JAMA Netw Open. 2019;2(11):e1914378. doi:10.1001/jamanetworkopen.2019.14378
Abstract Full Text pdf link PDF

HEALTH POLICY

Effect of Escalating Financial Incentive Rewards on Maintenance of Weight Loss: A Randomized Clinical Trial

This randomized clinical trial assesses an escalating lottery-based incentive tied to daily self-weighing for weight loss maintenance among adults in an online weight management program.

JAMA Netw Open. 2019;2(11):e1914393. doi:10.1001/jamanetworkopen.2019.14393
Abstract Full Text pdf link PDF

PSYCHIATRY

Association of Childhood Exposure to Nitrogen Dioxide and Polygenic Risk Score for Schizophrenia With the Risk of Developing Schizophrenia

This Danish population-based cohort study uses national registry data to evaluate the association of exposure to nitrogen dioxide in childhood and genetic liability for schizophrenia with the risk of developing schizophrenia.

JAMA Netw Open. 2019;2(11):e1914401. doi:10.1001/jamanetworkopen.2019.14401
Abstract Full Text pdf link PDF

SURGERY

Association of Sex With Postoperative Mortality Among Patients With Heart Failure Who Underwent Elective Noncardiac Operations

This cohort study evaluates whether sex is associated with postoperative mortality among patients with heart failure who underwent elective noncardiac operations.

JAMA Netw Open. 2019;2(11):e1914420. doi:10.1001/jamanetworkopen.2019.14420
Abstract Full Text pdf link PDF

PEDIATRICS

Effectiveness of Universal School-Based Screening vs Targeted Screening for Major Depressive Disorder Among Adolescents: A Trial Protocol for the Screening in High Schools to Identify, Evaluate, and Lower Depression (SHIELD) Randomized Clinical Trial

This trial protocol describes a randomized clinical trial that will compare the effectiveness of universal school-based screening for adolescent major depressive disorder vs the existing process of targeted screening based on observable behavior.

JAMA Netw Open. 2019;2(11):e1914427. doi:10.1001/jamanetworkopen.2019.14427
Abstract Full Text pdf link PDF

HEALTH POLICY

Advance Care Planning Claims and Health Care Utilization Among Seriously Ill Patients Near the End of Life

This cohort study examines the association between billed advance care planning encounters and subsequent health care utilization among seriously ill patients near the end of life.

JAMA Netw Open. 2019;2(11):e1914471. doi:10.1001/jamanetworkopen.2019.14471
Abstract Full Text pdf link PDF

ONCOLOGY

Clinicians’ Perspectives on Barriers to Discussing Infertility and Fertility Preservation With Young Women With Cancer

This qualitative study uses interviews with 22 Canadian clinicians to examine the perceived barriers to discussing fertility and fertility preservation with young women with cancer.

JAMA Netw Open. 2019;2(11):e1914511. doi:10.1001/jamanetworkopen.2019.14511
Abstract Full Text pdf link PDF

PEDIATRICS

Effect of a Community Agency–Administered Nurse Home Visitation Program on Program Use and Maternal and Infant Health Outcomes: A Randomized Clinical Trial

This randomized clinical trial examines the effects of a community agency–administered postnatal nurse home visitation program on child protective services investigations for maltreatment and other maternal and child health-related outcomes.

JAMA Netw Open. 2019;2(11):e1914522. doi:10.1001/jamanetworkopen.2019.14522
Abstract Full Text pdf link PDF

HEALTH POLICY

Cost-Sharing Disparities for Out-of-Network Care for Adults With Behavioral Health Conditions

This cross-sectional study evaluates the cost-sharing payments for out-of-network care for insurance plan enrollees with mental health conditions, alcohol use disorders, or drug use disorders compared with those with congestive heart failure or diabetes.

JAMA Netw Open. 2019;2(11):e1914554. doi:10.1001/jamanetworkopen.2019.14554
Abstract Full Text pdf link PDF

PEDIATRICS

Association of Chorioamnionitis With Bronchopulmonary Dysplasia Among Preterm Infants: A Systematic Review, Meta-analysis, and Metaregression

This systematic review, meta-analysis, and metaregression of clinical studies explores the association between chorioamnionitis and bronchopulmonary dysplasia in preterm infants.

JAMA Netw Open. 2019;2(11):e1914611. doi:10.1001/jamanetworkopen.2019.14611
Abstract Full Text pdf link PDF

GASTROENTEROLOGY AND HEPATOLOGY

Attention-Based Deep Neural Networks for Detection of Cancerous and Precancerous Esophagus Tissue on Histopathological Slides

This diagnostic study describes a novel attention-based deep neural network framework for classifying microscopy images to identify Barrett esophagus and esophageal adenocarcinoma.

JAMA Netw Open. 2019;2(11):e1914645. doi:10.1001/jamanetworkopen.2019.14645
Abstract Full Text pdf link PDF

HEALTH INFORMATICS

Machine Learning and Natural Language Processing for Geolocation-Centric Monitoring and Characterization of Opioid-Related Social Media Chatter

This cross-sectional study develops and validates a machine learning method for collecting and classifying data from opioid-related postings on a social media platform.

JAMA Netw Open. 2019;2(11):e1914672. doi:10.1001/jamanetworkopen.2019.14672
Abstract Full Text pdf link PDF

ONCOLOGY

Association Between Antidiabetic Medications and Prostate-Specific Antigen Levels and Biopsy Results

This cohort study examines the association between antidiabetic medication and prostate-specific antigen (PSA) levels, frequency of PSA testing and biopsy, and detection of prostate cancer at biopsy among Swedish men with diabetes.

JAMA Netw Open. 2019;2(11):e1914689. doi:10.1001/jamanetworkopen.2019.14689
Abstract Full Text pdf link PDF

HEALTH POLICY

Association of the Mandatory Medicare Bundled Payment With Joint Replacement Outcomes in Hospitals With Disadvantaged Patients

This cohort study examines changes in health care spending, use, and quality of care after the implementation of Medicare’s first mandatory bundled payment system at participating hospitals and among dual-eligible patients.

JAMA Netw Open. 2019;2(11):e1914696. doi:10.1001/jamanetworkopen.2019.14696
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Assessment of Prevention Research Measuring Leading Risk Factors and Causes of Mortality and Disability Supported by the US National Institutes of Health

This cross-sectional study characterizes National Institutes of Health (NIH) support for primary and secondary prevention research in humans and related methods research of the leading risk factors or causes of death or disability as outcomes or exposures.

JAMA Netw Open. 2019;2(11):e1914718. doi:10.1001/jamanetworkopen.2019.14718
Abstract Full Text pdf link PDF

OBSTETRICS AND GYNECOLOGY

Effect of Mailed Human Papillomavirus Test Kits vs Usual Care Reminders on Cervical Cancer Screening Uptake, Precancer Detection, and Treatment: A Randomized Clinical Trial

This randomized clinical trial evaluates the effectiveness of mailed self-test kits for human papillomavirus (HPV) vs usual care for detection and treatment of cervical precancers and uptake of cervical cancer screening.

JAMA Netw Open. 2019;2(11):e1914729. doi:10.1001/jamanetworkopen.2019.14729
Abstract Full Text pdf link PDF

RHEUMATOLOGY

Demographic Characteristics of Participants in Rheumatoid Arthritis Randomized Clinical Trials: A Systematic Review

This systematic review examines the representation in rheumatoid arthritis randomized clinical trials of racial/ethnic minority groups compared with the representation of these populations in the United States and the representation of women and elderly people with the prevalence of rheumatoid arthritis among these groups nationally.

JAMA Netw Open. 2019;2(11):e1914745. doi:10.1001/jamanetworkopen.2019.14745
Abstract Full Text pdf link PDF

ORTHOPEDICS

Incidence of Late-Diagnosed Hip Dislocation After Universal Clinical Screening in Sweden

This nested case-control study investigates the incidence and risk factors of late-diagnosed hip dislocation among Swedish children undergoing clinical screening for hip instability as neonates.

JAMA Netw Open. 2019;2(11):e1914779. doi:10.1001/jamanetworkopen.2019.14779
Abstract Full Text pdf link PDF

GLOBAL HEALTH

Association of Exposure to Civil Conflict With Maternal Resilience and Maternal and Child Health and Health System Performance in Afghanistan

This survey study evaluates associations of conflict severity with improvement of health system performance, use of health services, and child nutrition outcomes in Afghanistan during the 2003 to 2018 reconstruction period.

JAMA Netw Open. 2019;2(11):e1914819. doi:10.1001/jamanetworkopen.2019.14819
Abstract Full Text pdf link PDF

HEALTH POLICY

Association of Specialist Physician Payment Model With Visit Frequency, Quality, and Costs of Care for People With Chronic Disease

This population-based cohort study examines the visit frequency, quality of care, and cost for patients with chronic diseases seen by fee-for-service vs salaried specialist physicians.

JAMA Netw Open. 2019;2(11):e1914861. doi:10.1001/jamanetworkopen.2019.14861
Abstract Full Text pdf link PDF

GENETICS AND GENOMICS

Assessment of the Association of D2 Dopamine Receptor Gene and Reported Allele Frequencies With Alcohol Use Disorders: A Systematic Review and Meta-analysis

This meta-analysis examines the association between the D2 dopamine receptor gene (DRD2) and alcohol use disorder.

JAMA Netw Open. 2019;2(11):e1914940. doi:10.1001/jamanetworkopen.2019.14940
Abstract Full Text pdf link PDF

SUBSTANCE USE AND ADDICTION

Effect of Intranasal vs Intramuscular Naloxone on Opioid Overdose: A Randomized Clinical Trial

This randomized clinical trial compares 2 administration methods for the opioid antagonist naloxone in individuals served by a medically supervised drug-injecting facility in Australia.

JAMA Netw Open. 2019;2(11):e1914977. doi:10.1001/jamanetworkopen.2019.14977
Abstract Full Text pdf link PDF

EMERGENCY MEDICINE

Bimodal Release Ondansetron for Acute Gastroenteritis Among Adolescents and Adults: A Randomized Clinical Trial

This randomized clinical trial examines the efficacy of an immediate and sustained release oral ondansetron tablet in preventing vomiting for up to 24 hours in adolescents and adults with gastroenteritis.

JAMA Netw Open. 2019;2(11):e1914988. doi:10.1001/jamanetworkopen.2019.14988
Abstract Full Text pdf link PDF

PEDIATRICS

Association of Intestinal Alkaline Phosphatase With Necrotizing Enterocolitis Among Premature Infants

This diagnostic study evaluates whether aberrant intestinal alkaline phosphatase biochemistry in infant stool is a molecular biomarker for necrotizing enterocolitis and not associated with sepsis in the absence of necrotizing enterocolitis.

JAMA Netw Open. 2019;2(11):e1914996. doi:10.1001/jamanetworkopen.2019.14996
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

Appropriateness of Surgical Antimicrobial Prophylaxis Practices in Australia

This quality improvement study uses data from the Australian Surgical National Antimicrobial Prescribing Survey to describe prescribing practices for surgical antimicrobial prophylaxis and assess factors associated with appropriate prescribing.

JAMA Netw Open. 2019;2(11):e1915003. doi:10.1001/jamanetworkopen.2019.15003
Abstract Full Text pdf link PDF

CARDIOLOGY

Assessment of Jugular Venous Blood Flow Stasis and Thrombosis During Spaceflight

This cohort study examines the internal jugular vein flow and morphology of crew members of the International Space Station and the use of lower body negative pressure as a countermeasure to the headward fluid shift experienced during space flight.

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JAMA Netw Open. 2019;2(11):e1915011. doi:10.1001/jamanetworkopen.2019.15011
Abstract Full Text pdf link PDF

ORTHOPEDICS

Association of Early Postoperative Pain Trajectories With Longer-term Pain Outcome After Primary Total Knee Arthroplasty

This cohort study examines patterns of individual pain trajectories after total knee arthroplasty (TKA) and assesses their independent associations with longer-term pain outcome after surgery.

JAMA Netw Open. 2019;2(11):e1915105. doi:10.1001/jamanetworkopen.2019.15105
Abstract Full Text pdf link PDF

HEALTH POLICY

Association Between a Temporary Reduction in Access to Health Care and Long-term Changes in Hypertension Control Among Veterans After a Natural Disaster

This cohort study examines whether long-term changes in chronic disease control were associated with a 6-month decrease in access to health care services among veterans in New York City after superstorm Sandy in October 2012.

JAMA Netw Open. 2019;2(11):e1915111. doi:10.1001/jamanetworkopen.2019.15111
Abstract Full Text pdf link PDF

NUTRITION, OBESITY, AND EXERCISE

Association of Nutritional Support With Clinical Outcomes Among Medical Inpatients Who Are Malnourished or at Nutritional Risk: An Updated Systematic Review and Meta-analysis

This systematic review and meta-analysis assesses whether nutritional support is associated with better clinical outcomes in medical inpatients who are malnourished or at nutritional risk.

JAMA Netw Open. 2019;2(11):e1915138. doi:10.1001/jamanetworkopen.2019.15138
Abstract Full Text pdf link PDF

HEALTH POLICY

Association of Physician Characteristics With Perceptions and Experiences of Gender Equity in an Academic Internal Medicine Department

This mixed-methods qualitative study explores how physicians in the Department of Medicine at the University of Calgary perceive the climate for women physicians and compares perceptions and experience of gender inequity among physicians based on characteristics including gender, faculty status, parental status, and years in practice.

JAMA Netw Open. 2019;2(11):e1915165. doi:10.1001/jamanetworkopen.2019.15165
Abstract Full Text pdf link PDF

DIABETES AND ENDOCRINOLOGY

Trends in Self-perceived Weight Status, Weight Loss Attempts, and Weight Loss Strategies Among Adults in the United States, 1999-2016

This cross-sectional study examines trends in current measured body mass index (BMI) and weight, self-reported weight, self-perceived weight status, weight loss attempts, and weight loss strategies among adults in the United States using data from the National Health and Nutrition Examination Survey.

JAMA Netw Open. 2019;2(11):e1915219. doi:10.1001/jamanetworkopen.2019.15219
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Epidemiologic Characteristics of Multimorbidity and Sociodemographic Factors Associated With Multimorbidity in a Rapidly Aging Asian Country

This cross-sectional study conducted in Singapore examines the association between multimorbidity and sociodemographic factors and the association between mental health diseases and physical diseases, as well as their implications for the types and costs of health care use.

JAMA Netw Open. 2019;2(11):e1915245. doi:10.1001/jamanetworkopen.2019.15245
Abstract Full Text pdf link PDF

HEALTH INFORMATICS

Association of an Electronic Health Record Add-on App for Neonatal Bilirubin Management With Physician Efficiency and Care Quality

This quality improvement study evaluates whether an electronic health record add-on app for neonatal bilirubin management is associated with clinician time savings and improvements in patient care.

JAMA Netw Open. 2019;2(11):e1915343. doi:10.1001/jamanetworkopen.2019.15343
Abstract Full Text pdf link PDF

GERIATRICS

Association of Receiving Multiple, Concurrent Fracture-Associated Drugs With Hip Fracture Risk

This cohort study estimates hip fracture risk associated with concurrent exposure to multiple fracture-associated drugs.

JAMA Netw Open. 2019;2(11):e1915348. doi:10.1001/jamanetworkopen.2019.15348
Abstract Full Text pdf link PDF

HEMATOLOGY

Estimated Life Expectancy and Income of Patients With Sickle Cell Disease Compared With Those Without Sickle Cell Disease

This simulated cohort modeling study compares life expectancy, quality-adjusted life expectancy, and projected lifetime income between individuals with and without sickle cell disease.

JAMA Netw Open. 2019;2(11):e1915374. doi:10.1001/jamanetworkopen.2019.15374
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MEDICAL JOURNALS AND PUBLISHING

Assessment of Citations of the Retracted Article by Wakefield et al With Fraudulent Claims of an Association Between Vaccination and Autism

This cross-sectional study analyzes the characteristics of citations from scholarly literature that reference the 1998 article by Wakefield et al and investigates whether authors are accurately citing retracted references.

JAMA Netw Open. 2019;2(11):e1915552. doi:10.1001/jamanetworkopen.2019.15552
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SURGERY

Association of Cost Savings and Surgical Quality With Single-Vendor Procurement for Spinal Implants

This cohort study assesses whether single-vendor procurement of spinal implants is associated with reduce hospital expenditures without compromising surgical quality.

JAMA Netw Open. 2019;2(11):e1915567. doi:10.1001/jamanetworkopen.2019.15567
Abstract Full Text pdf link PDF

HEALTH POLICY

Association of Hospital Payment Profiles With Variation in 30-Day Medicare Cost for Inpatients With Heart Failure or Pneumonia

This cohort study analyzes Centers for Medicare & Medicaid Services data for heart failure and pneumonia discharges to ascertain hospital payment profiles associated with hospitalization costs for Medicare beneficiaries.

JAMA Netw Open. 2019;2(11):e1915604. doi:10.1001/jamanetworkopen.2019.15604
Abstract Full Text pdf link PDF

PEDIATRICS

Follow-up of Intervention to Prevent Dental Caries Among Indigenous Children in Australia: A Secondary Analysis of a Randomized Clinical Trial

This secondary analysis of a randomized clinical trial investigates the long-term success of a dental health intervention introduced in a trial involving Aboriginal and Torres Strait Islander children and their mothers in Australia.

JAMA Netw Open. 2019;2(11):e1915611. doi:10.1001/jamanetworkopen.2019.15611
Abstract Full Text pdf link PDF

ONCOLOGY

Association of an Active Choice Intervention in the Electronic Health Record Directed to Medical Assistants With Clinician Ordering and Patient Completion of Breast and Colorectal Cancer Screening Tests

This quality improvement study evaluates the association of an active choice intervention in the electronic health record directed to medical assistants with changes in ordering and patient completion of breast and colorectal cancer screening tests.

JAMA Netw Open. 2019;2(11):e1915619. doi:10.1001/jamanetworkopen.2019.15619
Abstract Full Text pdf link PDF

OBSTETRICS AND GYNECOLOGY

Association of Timing of Plasma Transfusion With Adverse Maternal Outcomes in Women With Persistent Postpartum Hemorrhage

This cohort study examines the association of timing of receipt of plasma transfusions among women experiencing persistent postpartum hemorrhage with adverse maternal outcomes.

JAMA Netw Open. 2019;2(11):e1915628. doi:10.1001/jamanetworkopen.2019.15628
Abstract Full Text pdf link PDF

SUBSTANCE USE AND ADDICTION

Association of Disability With Mortality From Opioid Overdose Among US Medicare Adults

This cohort study examines the rate of opioid overdose deaths among Medicare recipients younger than 65 years who qualified for Medicare because of disability.

JAMA Netw Open. 2019;2(11):e1915638. doi:10.1001/jamanetworkopen.2019.15638
Abstract Full Text pdf link PDF

HEALTH INFORMATICS

Contemporary Views of Research Participant Willingness to Participate and Share Digital Data in Biomedical Research

This mixed-methods survey and qualitative study investigates the association of willingness to participate in biomedical research and share social media data with source of study funding and online recruitment platform.

JAMA Netw Open. 2019;2(11):e1915717. doi:10.1001/jamanetworkopen.2019.15717
Abstract Full Text pdf link PDF

ONCOLOGY

Comparison of Long-term Survival of Patients With Early-Stage Non–Small Cell Lung Cancer After Surgery vs Stereotactic Body Radiotherapy

This cohort study compares long-term overall survival of patients with early-stage non–small cell lung cancer treated with stereotactic body radiotherapy vs surgery including various degrees of lymph node examination.

JAMA Netw Open. 2019;2(11):e1915724. doi:10.1001/jamanetworkopen.2019.15724
Abstract Full Text pdf link PDF

OBSTETRICS AND GYNECOLOGY

Comparison of HPV-16 and HPV-18 Genotyping and Cytological Testing as Triage Testing Within Human Papillomavirus–Based Screening in Mexico

This diagnostic study compares the efficiency and effectiveness of 6 triage testing scenarios for screening women with high-risk human papillomavirus (HPV) for referral for colposcopy.

JAMA Netw Open. 2019;2(11):e1915781. doi:10.1001/jamanetworkopen.2019.15781
Abstract Full Text pdf link PDF

GLOBAL HEALTH

An Evaluation of US Food and Drug Administration’s Program to Register HIV Drugs for Use in Resource-Constrained Settings

This cross-sectional study analyzes the contributions of the US Food and Drug Administration (FDA) program for reviewing antiretroviral drugs for use in low-resource settings, as well as areas for improvement.

JAMA Netw Open. 2019;2(11):e1915787. doi:10.1001/jamanetworkopen.2019.15787
Abstract Full Text pdf link PDF

PSYCHIATRY

Augmentation of Positive Valence System–Focused Cognitive Behavioral Therapy by Inaudible High-Frequency Sounds for Anhedonia: A Trial Protocol for a Pilot Study

This trial protocol describes a pilot study that tests the augmentation effect of inaudible, high-frequency sounds on the efficacy of positive valence system–focused cognitive behavioral therapy (CBT) to treat anhedonia.

JAMA Netw Open. 2019;2(11):e1915819. doi:10.1001/jamanetworkopen.2019.15819
Abstract Full Text pdf link PDF

ONCOLOGY

Association of Receipt of Positron Emission Tomography–Computed Tomography With Non–Small Cell Lung Cancer Mortality in the Veterans Affairs Health Care System

This cohort study examines the association of the use of positron emission tomography–computed tomography (PET-CT) and non–small cell lung cancer mortality in the US Department of Veterans Affairs health care system from 2000 to 2013.

JAMA Netw Open. 2019;2(11):e1915828. doi:10.1001/jamanetworkopen.2019.15828
Abstract Full Text pdf link PDF

ENVIRONMENTAL HEALTH

Burden of Cause-Specific Mortality Associated With PM2.5 Air Pollution in the United States

This cohort study identifies causes of death associated with ambient fine particulate matter (PM2.5) air pollution in the United States and estimates the burden of death for each cause.

JAMA Netw Open. 2019;2(11):e1915834. doi:10.1001/jamanetworkopen.2019.15834
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MEDICAL EDUCATION

Association of a Multisite Interprofessional Education Initiative With Quality of Primary Care

This study estimates the association of a multisite interprofessional education initiative in the US Department of Veterans Affairs primary care clinics with quality of care.

JAMA Netw Open. 2019;2(11):e1915943. doi:10.1001/jamanetworkopen.2019.15943
Abstract Full Text pdf link PDF

HEALTH POLICY

Consistency of Recommendations for Evaluation and Management of Hypertension

This cross-sectional study examines 8 clinical practice guidelines for consistency in recommendations for diagnosis and management of hypertension.

JAMA Netw Open. 2019;2(11):e1915975. doi:10.1001/jamanetworkopen.2019.15975
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CARDIOLOGY

Comparison of Cardiovascular Risk Factors and Outcomes Among Practicing Physicians vs the General Population in Ontario, Canada

This cohort study compares cardiac risk factor burden, health services use, and major cardiovascular event incidence between physicians and the general population in Ontario, Canada.

JAMA Netw Open. 2019;2(11):e1915983. doi:10.1001/jamanetworkopen.2019.15983
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GLOBAL HEALTH

Coauthor Country Affiliations in International Collaborative Research Funded by the US National Institutes of Health, 2009 to 2017

This cross-sectional study uses bibliometric analysis to quantify the extent and relevance of international research collaborations funded by the US National Institutes of Health.

JAMA Netw Open. 2019;2(11):e1915989. doi:10.1001/jamanetworkopen.2019.15989
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INFECTIOUS DISEASES

Adjunctive Rifampin Therapy For Diabetic Foot Osteomyelitis in the Veterans Health Administration

This cohort study compares amputation and mortality rates among patients treated in the Veterans Health Administration for diabetic foot osteomyelitis with and without rifampin.

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JAMA Netw Open. 2019;2(11):e1916003. doi:10.1001/jamanetworkopen.2019.16003
Abstract Full Text pdf link PDF

ORTHOPEDICS

Inaugural Readmission Penalties for Total Hip and Total Knee Arthroplasty Procedures Under the Hospital Readmissions Reduction Program

This case-control study evaluates the first year of penalties assessed by the Hospital Readmissions Reduction Program policy of the Centers for Medicare and Medicaid Services to investigate whether an association exists between penalties and surgical volume or characteristics of hospitals or patients undergoing elective total hip arthroplasty or total knee arthroplasty.

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JAMA Netw Open. 2019;2(11):e1916008. doi:10.1001/jamanetworkopen.2019.16008
Abstract Full Text pdf link PDF CME & MOC

SUBSTANCE USE AND ADDICTION

Associations of Parental Marijuana Use With Offspring Marijuana, Tobacco, and Alcohol Use and Opioid Misuse

This cross-sectional study examines the associations of parental marijuana use with marijuana, tobacco, and alcohol use and opioid misuse in their adolescent or young adult offspring.

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JAMA Netw Open. 2019;2(11):e1916015. doi:10.1001/jamanetworkopen.2019.16015
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Association Between Parental Educational Attainment and Youth Outcomes and Role of Race/Ethnicity

This cross-sectional study uses data from the Population Assessment of Tobacco and Health survey to explore racial and ethnic differences in the associations between parental educational attainment and youth outcomes among US adolescents.

JAMA Netw Open. 2019;2(11):e1916018. doi:10.1001/jamanetworkopen.2019.16018
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CARDIOLOGY

Development and Validation of a Model for Predicting the Risk of Acute Kidney Injury Associated With Contrast Volume Levels During Percutaneous Coronary Intervention

This prognostic study quantifies the association of contrast volume during percutaneous coronary intervention with the risk of acute kidney injury, accounting for the possibility of nonlinearity and heterogeneity among different baseline risks.

JAMA Netw Open. 2019;2(11):e1916021. doi:10.1001/jamanetworkopen.2019.16021
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ONCOLOGY

Estimation of Percentage of Patients With Fibroblast Growth Factor Receptor Alterations Eligible for Off-label Use of Erdafitinib

This cross-sectional study estimates the potential upper bound of off-label use of erdafitinib to treat advanced cancer with fibroblast growth factor receptor (FGFR) gene alterations, compares it to the upper bound of on-label use in urothelial cancer, and reviews studies that may support off-label use.

JAMA Netw Open. 2019;2(11):e1916091. doi:10.1001/jamanetworkopen.2019.16091
Abstract Full Text pdf link PDF

HEALTH POLICY

Association Between Physician Depressive Symptoms and Medical Errors: A Systematic Review and Meta-analysis

This systematic review and meta-analysis examines whether physician depressive symptoms are associated with the risk for perceived or observed medical errors.

JAMA Netw Open. 2019;2(11):e1916097. doi:10.1001/jamanetworkopen.2019.16097
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PHARMACY AND CLINICAL PHARMACOLOGY

Association Between Acute Gastroenteritis and Continuous Use of Proton Pump Inhibitors During Winter Periods of Highest Circulation of Enteric Viruses

This cohort study investigates the association between continuous proton pump inhibitor therapy and acute gastroenteritis due to infection with enteric viruses during the 2015 to 2016 winter epidemic in France.

JAMA Netw Open. 2019;2(11):e1916205. doi:10.1001/jamanetworkopen.2019.16205
Abstract Full Text pdf link PDF

ONCOLOGY

Efficacy and Safety of Gemcitabine With Trastuzumab and Pertuzumab After Prior Pertuzumab-Based Therapy Among Patients With Human Epidermal Growth Factor Receptor 2–Positive Metastatic Breast Cancer: A Phase 2 Clinical Trial

This phase 2 clinical trial evaluates the efficacy and safety of pertuzumab in combination with gemcitabine and trastuzumab after prior treatment with pertuzumab for human epidermal growth factor receptor 2 (ERBB2, formerly HER2)–positive metastatic breast cancer.

JAMA Netw Open. 2019;2(11):e1916211. doi:10.1001/jamanetworkopen.2019.16211
Abstract Full Text pdf link PDF

PHARMACY AND CLINICAL PHARMACOLOGY

Trends and Rapidity of Dose Tapering Among Patients Prescribed Long-term Opioid Therapy, 2008-2017

This cohort study characterizes US trends in opioid dose tapering among patients prescribed long-term opioids from 2008 to 2017 and identifies patient-level variables associated with tapering and a more rapid tapering rate.

JAMA Netw Open. 2019;2(11):e1916271. doi:10.1001/jamanetworkopen.2019.16271
Abstract Full Text pdf link PDF

DIABETES AND ENDOCRINOLOGY

Trends in Diabetic Retinopathy, Visual Acuity, and Treatment Outcomes for Patients Living With Diabetes in a Fundus Photograph–Based Diabetic Retinopathy Screening Program in Bangladesh

This cross-sectional study examines a novel fundus photograph–based eye screening model for early detection of diabetic retinopathy to prevent vision loss in Bangladeshi individuals with diabetes.

JAMA Netw Open. 2019;2(11):e1916285. doi:10.1001/jamanetworkopen.2019.16285
Abstract Full Text pdf link PDF

SUBSTANCE USE AND ADDICTION

Association Between Marijuana Use and Risk of Cancer: A Systematic Review and Meta-analysis

This systematic review and meta-analysis assesses the association of marijuana use with the development of cancer in adults with at least 1 joint-year exposure (equivalent to 1 joint per day for 1 year).

JAMA Netw Open. 2019;2(11):e1916318. doi:10.1001/jamanetworkopen.2019.16318
Abstract Full Text pdf link PDF

SURGERY

Costs Associated With Modifiable Risk Factors in Ventral and Incisional Hernia Repair

This cross-sectional study examines the attributable association of modifiable risk factors for adverse outcomes after hernia repair and increased health care spending associated with these adverse outcomes.

JAMA Netw Open. 2019;2(11):e1916330. doi:10.1001/jamanetworkopen.2019.16330
Abstract Full Text pdf link PDF

NUTRITION, OBESITY, AND EXERCISE

Association of Obesity With Septic Complications After Major Abdominal Surgery: A Secondary Analysis of the RELIEF Randomized Clinical Trial

This secondary analysis of the Restrictive vs Liberal Fluid Therapy for Major Abdominal Surgery (RELIEF) randomized clinical trial compares the value of waist circumference with the value of waist-to-hip ratio and body mass index in predicting adverse outcomes, including major septic complications and persistent disability, following major abdominal surgery.

JAMA Netw Open. 2019;2(11):e1916345. doi:10.1001/jamanetworkopen.2019.16345
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open access Invited Commentary

PEDIATRICS

It’s Time to Support, Rather Than Punish, Pregnant Women With Substance Use Disorder

JAMA Netw Open. 2019;2(11):e1914135. doi:10.1001/jamanetworkopen.2019.14135
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INFECTIOUS DISEASES

HIV Prevention and Treatment Scale-up and Community HIV Incidence in KwaZulu-Natal, South Africa

JAMA Netw Open. 2019;2(11):e1914408. doi:10.1001/jamanetworkopen.2019.14408
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HEALTH POLICY

Placing Value on End-of-Life Care—Is It Time for a New Taxonomy?

JAMA Netw Open. 2019;2(11):e1914466. doi:10.1001/jamanetworkopen.2019.14466
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PUBLIC HEALTH

Our Response to Opioid Overdose Deaths Must Be as Nimble as Illicit Opioid Markets

JAMA Netw Open. 2019;2(11):e1914634. doi:10.1001/jamanetworkopen.2019.14634
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ONCOLOGY

Diabetes Medications, Prostate-Specific Antigen Values, and the Chemoprevention of Prostate Cancer

JAMA Netw Open. 2019;2(11):e1914644. doi:10.1001/jamanetworkopen.2019.14644
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OBSTETRICS AND GYNECOLOGY

Home Screening for Human Papillomavirus Falls Short in Initial Application, Remains Promising

JAMA Netw Open. 2019;2(11):e1914704. doi:10.1001/jamanetworkopen.2019.14704
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HEALTH POLICY

Do Salaried Physician Specialists Provide Less Care to Patients With Chronic Disease?

JAMA Netw Open. 2019;2(11):e1914885. doi:10.1001/jamanetworkopen.2019.14885
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INFECTIOUS DISEASES

How Can We Routinely Measure Appropriateness of Antimicrobial Use in Hospitals at a National Level?

JAMA Netw Open. 2019;2(11):e1915030. doi:10.1001/jamanetworkopen.2019.15030
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NUTRITION, OBESITY, AND EXERCISE

Nutritional Support Among Medical Inpatients—Feed the Cold (and Malnourished) and Starve the Febrile

JAMA Netw Open. 2019;2(11):e1915707. doi:10.1001/jamanetworkopen.2019.15707
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ONCOLOGY

The Role of Positron Emission Tomography–Computed Tomography in the Workup of Non–Small Cell Lung Cancer

JAMA Netw Open. 2019;2(11):e1915873. doi:10.1001/jamanetworkopen.2019.15873
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SUBSTANCE USE AND ADDICTION

A Renewed Focus on Youth Substance Use Prevention Is Needed Among Health Care Professionals and Families

JAMA Netw Open. 2019;2(11):e1916058. doi:10.1001/jamanetworkopen.2019.16058
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PHARMACY AND CLINICAL PHARMACOLOGY

Further Evidence to Monitor Long-term Proton Pump Inhibitor Use

JAMA Netw Open. 2019;2(11):e1916184. doi:10.1001/jamanetworkopen.2019.16184
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open access Research Letter

PUBLIC HEALTH

Newspaper Adherence to Media Reporting Guidelines for the Suicide Deaths of Kate Spade and Anthony Bourdain

This cross-sectional study examines newspaper adherence to reporting guidelines for suicide after the deaths of Kate Spade and Anthony Bourdain.

JAMA Netw Open. 2019;2(11):e1914517. doi:10.1001/jamanetworkopen.2019.14517
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ONCOLOGY

Publication Rate and Characteristics of Lung Cancer Clinical Trials

This cross-sectional study estimates the publication rate of clinical trials related to lung cancer and examines the characteristics of published vs unpublished trials.

JAMA Netw Open. 2019;2(11):e1914531. doi:10.1001/jamanetworkopen.2019.14531
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HEALTH POLICY

Access to Care Among Individuals Who Experienced Medicaid Lockouts After Premium Nonpayment

This survey study compares the demographic characteristics, access to care, and health status of recent Medicaid enrollees in Wisconsin with and without experience of Medicaid lockouts.

JAMA Netw Open. 2019;2(11):e1914561. doi:10.1001/jamanetworkopen.2019.14561
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PUBLIC HEALTH

Association of Law Enforcement Seizures of Heroin, Fentanyl, and Carfentanil With Opioid Overdose Deaths in Ohio, 2014-2017

This cross-sectional study examines the association of law enforcement seizures of heroin, fentanyl, and carfentanil with opioid overdose deaths in Ohio from 2014 to 2017.

JAMA Netw Open. 2019;2(11):e1914666. doi:10.1001/jamanetworkopen.2019.14666
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ONCOLOGY

Characteristics of Immune Checkpoint Inhibitors Trials Associated With Inclusion of Patients With HIV: A Systematic Review and Meta-analysis

This systematic review and meta-analysis examines factors associated with inclusion of patients with HIV in clinical trials of immune checkpoint inhibitors.

JAMA Netw Open. 2019;2(11):e1914816. doi:10.1001/jamanetworkopen.2019.14816
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NUTRITION, OBESITY, AND EXERCISE

Discrepancies in the Registries of Diet vs Drug Trials

This cross-sectional study examines discrepancies between registered protocols and subsequent publications for drug and diet trials whose findings were published in prominent clinical journals in the last decade.

JAMA Netw Open. 2019;2(11):e1915360. doi:10.1001/jamanetworkopen.2019.15360
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PUBLIC HEALTH

Nicotine Absorption Profile Among Regular Users of a Pod-Based Electronic Nicotine Delivery System

This case series characterizes nicotine absorption among adults who regularly use a pod-based electronic nicotine delivery system.

JAMA Netw Open. 2019;2(11):e1915494. doi:10.1001/jamanetworkopen.2019.15494
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PUBLIC HEALTH

Perceived Comparative Harm of Cigarettes and Electronic Nicotine Delivery Systems

This survey study examines the changing attitudes regarding the perceived harm of electronic nicotine delivery systems (ENDS) among smokers, nonsmokers, and ENDS users from 2017 to 2018.

JAMA Netw Open. 2019;2(11):e1915680. doi:10.1001/jamanetworkopen.2019.15680
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MEDICAL JOURNALS AND PUBLISHING

Prevalence of Women Authors in Family Medicine Literature

This cross-sectional study examines the prevalence of women authors in 5 prominent family medicine journals.

JAMA Netw Open. 2019;2(11):e1916029. doi:10.1001/jamanetworkopen.2019.16029
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MEDICAL EDUCATION

Patient Perspectives on the Cultural Competence of US Health Care Professionals

This survey study uses data from the 2017 National Health Interview Survey to examine patients’ perspectives on the cultural competence of US health care professionals.

JAMA Netw Open. 2019;2(11):e1916105. doi:10.1001/jamanetworkopen.2019.16105
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MEDICAL EDUCATION

Assessment of Gender Equity Among Invited Speakers and Award Recipients at US Annual Medical Education Conferences

This cross-sectional study assesses the gender balance of invited speakers and award recipients at US annual medical education conferences.

JAMA Netw Open. 2019;2(11):e1916222. doi:10.1001/jamanetworkopen.2019.16222
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open access Correction

Error in Key Points

JAMA Netw Open. 2019;2(11):e1916430. doi:10.1001/jamanetworkopen.2019.16430
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Error in Key Points

JAMA Netw Open. 2019;2(11):e1916768. doi:10.1001/jamanetworkopen.2019.16768
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Error in Results

JAMA Netw Open. 2019;2(11):e1917197. doi:10.1001/jamanetworkopen.2019.17197
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Error in Byline

JAMA Netw Open. 2019;2(11):e1917637. doi:10.1001/jamanetworkopen.2019.17637
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Errors in Results, Discussion, and Table 3

JAMA Netw Open. 2019;2(11):e1917818. doi:10.1001/jamanetworkopen.2019.17818
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open access JAMA Network Open Masthead

JAMA Network Open

JAMA Netw Open. 2019;2(11):e1915489. doi:10.1001/jamanetworkopen.2019.15489
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