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December 2019 - May 2018

Decade

Year

Issue

December 2019, Vol 2, No. 12

open access Original Investigation

NEUROLOGY

Association of Longitudinal β-Amyloid Accumulation Determined by Positron Emission Tomography With Clinical and Cognitive Decline in Adults With Probable Lewy Body Dementia

This cohort study determines the trajectory of β-amyloid accumulation among patients with probable dementia with Lewy bodies and investigates the associations of β-amyloid accumulation with measures of clinical and cognitive decline over time in dementia with Lewy bodies.

JAMA Netw Open. 2019;2(12):e1916439. doi:10.1001/jamanetworkopen.2019.16439
Abstract Full Text pdf link PDF

CARDIOLOGY

Trends in Cause-Specific Outcomes Among Individuals With Type 2 Diabetes and Heart Failure in the United Kingdom, 1998-2017

This cohort study investigates changes in cause-specific outcomes and trends associated with type 2 diabetes among individuals with incident heart failure in the United Kingdom from 1998 to 2017.

JAMA Netw Open. 2019;2(12):e1916447. doi:10.1001/jamanetworkopen.2019.16447
Abstract Full Text pdf link PDF

EMERGENCY MEDICINE

Association of Patient and Visit Characteristics With Rate and Timing of Urologic Procedures for Patients Discharged From the Emergency Department With Renal Colic

This cohort study assesses the rate and timing of urologic procedures performed after an emergency department visit for renal colic and the factors associated with receipt of an intervention within 60 days.

JAMA Netw Open. 2019;2(12):e1916454. doi:10.1001/jamanetworkopen.2019.16454
Abstract Full Text pdf link PDF

EMERGENCY MEDICINE

Assessment of Unintentional Duplicate Orders by Emergency Department Clinicians Before and After Implementation of a Visual Aid in the Electronic Health Record Ordering System

This cohort study determines whether a simple visual aid is associated with a reduction in duplicate ordering of tests and medications in an emergency department.

JAMA Netw Open. 2019;2(12):e1916499. doi:10.1001/jamanetworkopen.2019.16499
Abstract Full Text pdf link PDF

SURGERY

Cost-effectiveness of Finger Replantation Compared With Revision Amputation

This economic evaluation compares the cost-effectiveness of finger replantation vs revision amputation after traumatic finger amputation.

JAMA Netw Open. 2019;2(12):e1916509. doi:10.1001/jamanetworkopen.2019.16509
Abstract Full Text pdf link PDF

SUBSTANCE USE AND ADDICTION

Comparison of Rural vs Urban Direct-to-Physician Commercial Promotion of Medications for Treating Opioid Use Disorder

This cross-sectional study compares direct-to-physician commercial promotion of medications for opioid use disorder in rural vs urban county locations.

JAMA Netw Open. 2019;2(12):e1916520. doi:10.1001/jamanetworkopen.2019.16520
Abstract Full Text pdf link PDF

IMMUNOLOGY

Association of Lymphopenia With Risk of Mortality Among Adults in the US General Population

This cohort study assesses whether lymphopenia is associated with reduced survival among outpatients enrolled in the US National Health and Nutrition Examination Survey.

JAMA Netw Open. 2019;2(12):e1916526. doi:10.1001/jamanetworkopen.2019.16526
Abstract Full Text pdf link PDF

GLOBAL HEALTH

Assessment of Barriers and Facilitators to the Delivery of Care for Noncommunicable Diseases by Nonphysician Health Workers in Low- and Middle-Income Countries: A Systematic Review and Qualitative Analysis

This systematic review and qualitative analysis examines the health system barriers to and facilitators of care for noncommunicable diseases by nonphysician health workers in low- and middle-income countries.

JAMA Netw Open. 2019;2(12):e1916545. doi:10.1001/jamanetworkopen.2019.16545
Abstract Full Text pdf link PDF

CARDIOLOGY

Association of Depressive Symptoms With Incident Cardiovascular Diseases in Middle-Aged and Older Chinese Adults

This cohort study examines the association between depressive symptoms and incident cardiovascular disease among middle-aged and older Chinese adults.

JAMA Netw Open. 2019;2(12):e1916591. doi:10.1001/jamanetworkopen.2019.16591
Abstract Full Text pdf link PDF

CARDIOLOGY

Association of β-Blocker Use With Heart Failure Hospitalizations and Cardiovascular Disease Mortality Among Patients With Heart Failure With a Preserved Ejection Fraction: A Secondary Analysis of the TOPCAT Trial

This secondary analysis of the TOPCAT randomized clinical trial examines the association of β-blocker use with heart failure (HF) hospitalizations and cardiovascular disease (CVD) mortality, overall and in strata of patients with an ejection fraction (EF) of 50% or greater or less than 50%.

JAMA Netw Open. 2019;2(12):e1916598. doi:10.1001/jamanetworkopen.2019.16598
Abstract Full Text pdf link PDF

NEUROLOGY

Association of Dietary Patterns in Midlife and Cognitive Function in Later Life in US Adults Without Dementia

This cohort study examines the association of dietary patterns in midlife with cognitive function in later life in US adults without dementia at baseline.

JAMA Netw Open. 2019;2(12):e1916641. doi:10.1001/jamanetworkopen.2019.16641
Abstract Full Text pdf link PDF

GERIATRICS

Comparison of Functional Status Improvements Among Patients With Stroke Receiving Postacute Care in Inpatient Rehabilitation vs Skilled Nursing Facilities

This cohort study examines the difference in improvement of functional status among patients with stroke who received postacute care in inpatient rehabilitation vs skilled nursing facilities.

JAMA Netw Open. 2019;2(12):e1916646. doi:10.1001/jamanetworkopen.2019.16646
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Association of Special Supplemental Nutrition Program for Women, Infants, and Children With Preterm Birth and Infant Mortality

This cohort study analyzes the association between participation in the Women, Infants, and Children (WIC) program and birth outcomes among low-income pregnant women in the United States by gestational age at birth and maternal race/ethnicity.

JAMA Netw Open. 2019;2(12):e1916722. doi:10.1001/jamanetworkopen.2019.16722
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Association of Aspirin Use With Mortality Risk Among Older Adult Participants in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial

This cohort study uses data from the Prostate, Lung, Colorectal, and Ovarian Cancer Screen Trial to examine the associations among regular aspirin use, obesity, and all-cause and cancer mortality among older adults.

JAMA Netw Open. 2019;2(12):e1916729. doi:10.1001/jamanetworkopen.2019.16729
Abstract Full Text pdf link PDF

HEALTH POLICY

Multiyear Rehospitalization Rates and Hospital Outcomes in an Integrated Health Care System

This cohort study examines rehospitalization factors, hospitalization and mortality, discharge disposition, and the changes in these variables over time among all adult patients in the Kaiser Permanente Northern California health system.

JAMA Netw Open. 2019;2(12):e1916769. doi:10.1001/jamanetworkopen.2019.16769
Abstract Full Text pdf link PDF

NUTRITION, OBESITY, AND EXERCISE

Association of Periconception Paternal Body Mass Index With Persistent Changes in DNA Methylation of Offspring in Childhood

This cohort study investigates the associations between periconception paternal body mass index (BMI) and DNA methylation patterns in offspring.

JAMA Netw Open. 2019;2(12):e1916777. doi:10.1001/jamanetworkopen.2019.16777
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Association Between e-Cigarette Use and Depression in the Behavioral Risk Factor Surveillance System, 2016-2017

This cross-sectional study examines the association between electronic cigarette (e-cigarette) use and depression in a nationally representative sample of the adult population in the United States.

JAMA Netw Open. 2019;2(12):e1916800. doi:10.1001/jamanetworkopen.2019.16800
Abstract Full Text pdf link PDF

COMPLEMENTARY AND ALTERNATIVE MEDICINE

Effect of True and Sham Acupuncture on Radiation-Induced Xerostomia Among Patients With Head and Neck Cancer: A Randomized Clinical Trial

This randomized clinical trial examines the efficacy of true or sham acupuncture vs standard care in the treatment of radiation-induced xerostomia among patients in the United States and China.

JAMA Netw Open. 2019;2(12):e1916910. doi:10.1001/jamanetworkopen.2019.16910
Abstract Full Text pdf link PDF

NEPHROLOGY

Risk Stratification for Postoperative Acute Kidney Injury in Major Noncardiac Surgery Using Preoperative and Intraoperative Data

This prognostic study evaluates the addition of preoperative and intraoperative data to prehospitalization data to identify patients at risk for postoperative acute kidney injury after undergoing major noncardiac surgery.

JAMA Netw Open. 2019;2(12):e1916921. doi:10.1001/jamanetworkopen.2019.16921
Abstract Full Text pdf link PDF

ONCOLOGY

Assessment of the Diagnostic Utility of Serum MicroRNA Classification in Patients With Diffuse Glioma

This diagnostic study establishes and assesses models to detect diffuse glioma and to differentiate glioblastoma, primary central nervous system lymphoma, and metastatic brain tumors.

JAMA Netw Open. 2019;2(12):e1916953. doi:10.1001/jamanetworkopen.2019.16953
Abstract Full Text pdf link PDF

IMAGING

Assessment of a Staging System for Sigmoid Colon Cancer Based on Tumor Deposits and Extramural Venous Invasion on Computed Tomography

This prognostic study assesses whether preoperative computed tomographic findings can be used for sigmoid colon cancer prognosis.

JAMA Netw Open. 2019;2(12):e1916987. doi:10.1001/jamanetworkopen.2019.16987
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Association Between Adolescent Blunt Use and the Uptake of Cigars

This cohort study examines the association of blunt use with cigar use among US adolescents.

JAMA Netw Open. 2019;2(12):e1917001. doi:10.1001/jamanetworkopen.2019.17001
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Patient Views on Religious Institutional Health Care

This population-based survey study examines patient views on religious institutional care, specifically whether they consider religious affiliation when selecting a health care facility and whether they believe that their personal choices about their health should take priority over a facility’s religious values.

JAMA Netw Open. 2019;2(12):e1917008. doi:10.1001/jamanetworkopen.2019.17008
Abstract Full Text pdf link PDF

HEALTH POLICY

Trends in Hospital-Based Specialty Palliative Care in the United States From 2013 to 2017

This cohort study characterizes current practice and trends among patients cared for and outcomes achieved by inpatient specialty palliative care services in the United States.

JAMA Netw Open. 2019;2(12):e1917043. doi:10.1001/jamanetworkopen.2019.17043
Abstract Full Text pdf link PDF

RHEUMATOLOGY

Association of Patient, Prescriber, and Region With the Initiation of First Prescription of Biologic Disease-Modifying Antirheumatic Drug Among Older Patients With Rheumatoid Arthritis and Identical Health Insurance Coverage

This cohort study evaluates the associations of patient, prescriber, and geographic region with differences in time to first prescription of biologic disease-modifying antirheumatic drug among older adults with rheumatoid arthritis and identical health insurance coverage in Ontario, Canada.

JAMA Netw Open. 2019;2(12):e1917053. doi:10.1001/jamanetworkopen.2019.17053
Abstract Full Text pdf link PDF

ONCOLOGY

Comparison of Conventional TNM and Novel TNMB Staging Systems for Non–Small Cell Lung Cancer

This cohort study examines whether incorporation of a molecular prognostic classifier into conventional TNM staging for non–small cell lung cancer improves estimation of disease-free survival.

JAMA Netw Open. 2019;2(12):e1917062. doi:10.1001/jamanetworkopen.2019.17062
Abstract Full Text pdf link PDF

HEALTH INFORMATICS

Effectiveness of a Hospital-Based Computerized Decision Support System on Clinician Recommendations and Patient Outcomes: A Randomized Clinical Trial

This randomized clinical trial assesses the effectiveness of a computerized decision support system that preappraises evidence and provides health professionals with actionable, patient-specific recommendations at the point of care.

JAMA Netw Open. 2019;2(12):e1917094. doi:10.1001/jamanetworkopen.2019.17094
Abstract Full Text pdf link PDF

NEUROLOGY

Association of Longitudinal Changes in Cerebrospinal Fluid Total Tau and Phosphorylated Tau 181 and Brain Atrophy With Disease Progression in Patients With Alzheimer Disease

This cohort study of participants with dominantly inherited Alzheimer disease examines the rates of change in cerebrospinal fluid levels of total tau (tTau) and phosphorylated tau 181 (pTau181) across the disease course and how the rates of change are associated with brain atrophy.

JAMA Netw Open. 2019;2(12):e1917126. doi:10.1001/jamanetworkopen.2019.17126
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

Global Epidemiologic Characteristics of Sexually Transmitted Infections Among Individuals Using Preexposure Prophylaxis for the Prevention of HIV Infection: A Systematic Review and Meta-analysis

This systematic review and meta-analysis estimates the prevalence of sexually transmitted infections at initiation of HIV preexposure prophylaxis (PrEP) and the incidence of sexually transmitted infections during use of HIV PrEP.

JAMA Netw Open. 2019;2(12):e1917134. doi:10.1001/jamanetworkopen.2019.17134
Abstract Full Text pdf link PDF

DIABETES AND ENDOCRINOLOGY

Health Outcomes Among Long-term Opioid Users With Testosterone Prescription in the Veterans Health Administration

This cohort study analyzes the association between testosterone and opioid use and improved health outcomes among male US military veterans with opioid-induced androgen deficiency.

JAMA Netw Open. 2019;2(12):e1917141. doi:10.1001/jamanetworkopen.2019.17141
Abstract Full Text pdf link PDF

HEALTH INFORMATICS

Development and Validation of a Machine Learning Model to Aid Discharge Processes for Inpatient Surgical Care

This prognostic study develops and validates the performance of a neural network machine learning model compared with a model based on median length of stay for predicting which patients are likely to be discharged within 24 hours from inpatient surgical care and their barriers to discharge.

JAMA Netw Open. 2019;2(12):e1917221. doi:10.1001/jamanetworkopen.2019.17221
Abstract Full Text pdf link PDF

PHARMACY AND CLINICAL PHARMACOLOGY

Trends in Prescription Analgesic Use Among Adults With Musculoskeletal Conditions in the United States, 1999-2016

This cross-sectional study uses data from the National Health and Nutrition Examination Study to evaluate trends in prescription opioid use and nonopioid analgesic use from 1999 to 2016 among US adults with functional limitations attributable to musculoskeletal conditions.

JAMA Netw Open. 2019;2(12):e1917228. doi:10.1001/jamanetworkopen.2019.17228
Abstract Full Text pdf link PDF

EMERGENCY MEDICINE

Incidence of, Risk Factors for, and Mortality Associated With Severe Acute Kidney Injury After Gunshot Wound

This cross-sectional study determines the incidence of and risk factors associated with severe acute kidney injury (AKI) and AKI requiring dialysis after gunshot wounds and the association of severe AKI and AKI requiring dialysis with mortality among civilians in the United States.

JAMA Netw Open. 2019;2(12):e1917254. doi:10.1001/jamanetworkopen.2019.17254
Abstract Full Text pdf link PDF

GERIATRICS

Associations of Regional Brain Structural Differences With Aging, Modifiable Risk Factors for Dementia, and Cognitive Performance

This cross-sectional study examines the associations of aging and modifiable risk factors for dementia with volume differences in brain regions known to be associated with Alzheimer disease and whether these volume differences are associated with cognitive performance.

JAMA Netw Open. 2019;2(12):e1917257. doi:10.1001/jamanetworkopen.2019.17257
Abstract Full Text pdf link PDF

ORTHOPEDICS

US Geographical Variation in Rates of Shoulder and Knee Arthroscopy and Association With Orthopedist Density

This cross-sectional study estimates time trends and geographical variations in rates of arthroscopic surgery among US states and investigates whether rates of arthroscopy are associated with geographic density of orthopedists.

JAMA Netw Open. 2019;2(12):e1917315. doi:10.1001/jamanetworkopen.2019.17315
Abstract Full Text pdf link PDF

CRITICAL CARE MEDICINE

Assessment of Variability in End-of-Life Care Delivery in Intensive Care Units in the United States

This cohort study describes the structures, processes, and variability of end-of-life care delivered in intensive care units in the United States.

JAMA Netw Open. 2019;2(12):e1917344. doi:10.1001/jamanetworkopen.2019.17344
Abstract Full Text pdf link PDF

NEUROLOGY

Racial Disparity in Cerebrospinal Fluid Amyloid and Tau Biomarkers and Associated Cutoffs for Mild Cognitive Impairment

This case-control study compares cerebrospinal fluid (CSF) amyloid and tau biomarkers for Alzheimer disease in African American and white individuals with normal cognition and with mild cognitive impairment.

JAMA Netw Open. 2019;2(12):e1917363. doi:10.1001/jamanetworkopen.2019.17363
Abstract Full Text pdf link PDF

NUTRITION, OBESITY, AND EXERCISE

Association of Adult Weight Gain With Major Health Outcomes Among Middle-aged Chinese Persons With Low Body Weight in Early Adulthood

This population-based cohort study investigates the association of adult weight gain with major health outcomes in middle-aged Chinese persons who had low body weight in early adulthood.

JAMA Netw Open. 2019;2(12):e1917371. doi:10.1001/jamanetworkopen.2019.17371
Abstract Full Text pdf link PDF

HEALTH POLICY

Assessment of Accuracy and Usability of a Fee Estimator for Ambulatory Care in an Integrated Health Care Delivery Network

This quality improvement study examines the accuracy and user experience of a cost estimator tool delivered via an online patient portal and informed by real-time data from third-party payers.

JAMA Netw Open. 2019;2(12):e1917445. doi:10.1001/jamanetworkopen.2019.17445
Abstract Full Text pdf link PDF

PSYCHIATRY

A Historical Examination of Military Records of US Army Suicide, 1819 to 2017

This cross-sectional study consolidates data on suicides among active-duty personnel in the US Army from 1819 to 2017 and identifies historical trends to separate them from more acute causal factors.

JAMA Netw Open. 2019;2(12):e1917448. doi:10.1001/jamanetworkopen.2019.17448
Abstract Full Text pdf link PDF

STATISTICS AND RESEARCH METHODS

Indication of Measures of Uncertainty for Statistical Significance in Abstracts of Published Oncology Trials: A Systematic Review and Meta-analysis

This systematic review and meta-analysis examines the expression of uncertainty in abstracts of published oncology randomized clinical trials.

JAMA Netw Open. 2019;2(12):e1917530. doi:10.1001/jamanetworkopen.2019.17530
Abstract Full Text pdf link PDF

PSYCHIATRY

Association of Postdisaster Depression and Posttraumatic Stress Disorder With Mortality Among Older Disaster Survivors of the 2011 Great East Japan Earthquake and Tsunami

This cohort study of community-dwelling survivors of the 2011 Great East Japan Earthquake and Tsunami assesses whether postdisaster depression and posttraumatic stress disorder are associated with mortality.

JAMA Netw Open. 2019;2(12):e1917550. doi:10.1001/jamanetworkopen.2019.17550
Abstract Full Text pdf link PDF

HEALTH POLICY

Variation in Facility-Level Rates of All-Cause and Potentially Preventable 30-Day Hospital Readmissions Among Medicare Fee-for-Service Beneficiaries After Discharge From Postacute Inpatient Rehabilitation

This cohort study examines the differences between 2 Centers for Medicare & Medicaid Services measures for 30-day rehospitalization after discharge from postacute inpatient rehabilitation.

JAMA Netw Open. 2019;2(12):e1917559. doi:10.1001/jamanetworkopen.2019.17559
Abstract Full Text pdf link PDF

PSYCHIATRY

Association of Suicide and Other Mortality With Emergency Department Presentation

This cohort study examines the association of suicide and other mortality risk within 1 year of emergency department presentation among patients presenting with deliberate self-harm, suicidal ideation, or any other chief concern.

JAMA Netw Open. 2019;2(12):e1917571. doi:10.1001/jamanetworkopen.2019.17571
Abstract Full Text pdf link PDF

SURGERY

Risk of Operative and Nonoperative Interventions Up to 4 Years After Roux-en-Y Gastric Bypass vs Vertical Sleeve Gastrectomy in a Nationwide US Commercial Insurance Claims Database

This cohort study compares the risk of operative and nonoperative interventions up to 4 years after Roux-en-Y gastric bypass vs vertical sleeve gastrectomy in patient groups matched on US region, year of surgery, body mass index category, and type 2 diabetes status.

JAMA Netw Open. 2019;2(12):e1917603. doi:10.1001/jamanetworkopen.2019.17603
Abstract Full Text pdf link PDF

NEUROLOGY

Characteristics and Incidence of Concussion Among a US Collegiate Undergraduate Population

This cohort study examines the incidence of sport-related and non–sport-related concussions among US undergraduate college students and varsity athletes stratified by sex and cause of concussion.

JAMA Netw Open. 2019;2(12):e1917626. doi:10.1001/jamanetworkopen.2019.17626
Abstract Full Text pdf link PDF

ENVIRONMENTAL HEALTH

Association of Prenatal and Perinatal Exposures to Particulate Matter With Changes in Hemoglobin A1c Levels in Children Aged 4 to 6 Years

This birth cohort study examines the association between prenatal and perinatal exposures to fine particulate matter (diameter <2.5 μm) and changes in hemoglobin A1c levels in children aged 4 to 6 years.

JAMA Netw Open. 2019;2(12):e1917643. doi:10.1001/jamanetworkopen.2019.17643
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Antiretroviral Prescribing Practices Among Pregnant Women Living With HIV in the United States, 2008-2017

This cohort study compares antiretroviral prescribing practices over time among pregnant women living with HIV with US Department of Health and Human Services treatment guidelines.

JAMA Netw Open. 2019;2(12):e1917669. doi:10.1001/jamanetworkopen.2019.17669
Abstract Full Text pdf link PDF

HEALTH INFORMATICS

Effect of a Computer-Based Decision Support Intervention on Autism Spectrum Disorder Screening in Pediatric Primary Care Clinics: A Cluster Randomized Clinical Trial

This randomized clinical trial examines whether computer-automated screening and clinical decision support can improve autism spectrum disorder screening rates in a pediatric primary care practice.

JAMA Netw Open. 2019;2(12):e1917676. doi:10.1001/jamanetworkopen.2019.17676
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Vitamin D and Calcium for the Prevention of Fracture: A Systematic Review and Meta-analysis

This systematic review and meta-analysis assesses the risk of fracture associated with differences in concentrations of 25-hydroxyvitamin D (25[OH]D) in observational studies and the effects of supplementation with vitamin D alone or in combination with calcium on fracture in randomized clinical trials.

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JAMA Netw Open. 2019;2(12):e1917789. doi:10.1001/jamanetworkopen.2019.17789
Abstract Full Text pdf link PDF

ENVIRONMENTAL HEALTH

Association Between Greenness Surrounding Schools and Kindergartens and Attention-Deficit/Hyperactivity Disorder in Children in China

This cross-sectional study evaluates the association between greenness surrounding schools or kindergartens and symptoms of attention-deficit/hyperactivity disorder among Chinese children.

JAMA Netw Open. 2019;2(12):e1917862. doi:10.1001/jamanetworkopen.2019.17862
Abstract Full Text pdf link PDF

CARDIOLOGY

Variation and Disparities in Awareness of Myocardial Infarction Symptoms Among Adults in the United States

This cross-sectional study evaluates the prevalence and characteristics of US adults who are unaware of the symptoms of and appropriate response to myocardial infarction.

JAMA Netw Open. 2019;2(12):e1917885. doi:10.1001/jamanetworkopen.2019.17885
Abstract Full Text pdf link PDF

EMERGENCY MEDICINE

Effect of a Motivational Interviewing–Based Intervention on Initiation of Mental Health Treatment and Mental Health After an Emergency Department Visit Among Suicidal Adolescents: A Randomized Clinical Trial

This randomized clinical trial examines whether a motivational interviewing–based intervention increases linkage of adolescents to outpatient mental health services and reduces depression symptoms and suicidal ideation in adolescents seeking emergency care for non–mental health–related concerns.

JAMA Netw Open. 2019;2(12):e1917941. doi:10.1001/jamanetworkopen.2019.17941
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Association of Race and Socioeconomic Status With Colorectal Cancer Screening, Colorectal Cancer Risk, and Mortality in Southern US Adults

This cohort study examines the associations of colorectal cancer screening and modalities with colorectal cancer incidence and mortality by race and socioeconomic status among southern US adults.

JAMA Netw Open. 2019;2(12):e1917995. doi:10.1001/jamanetworkopen.2019.17995
Abstract Full Text pdf link PDF

MEDICAL JOURNALS AND PUBLISHING

A Bibliometric Analysis of Top-Cited Journal Articles in Obstetrics and Gynecology

This cross-sectional bibliometric analysis identifies top-cited articles on obstetrics and gynecology topics and compares top-cited articles published in obstetrics and gynecology specialty journals with those published in general medical journals.

JAMA Netw Open. 2019;2(12):e1918007. doi:10.1001/jamanetworkopen.2019.18007
Abstract Full Text pdf link PDF

MEDICAL EDUCATION

Effect of Teaching Bayesian Methods Using Learning by Concept vs Learning by Example on Medical Students’ Ability to Estimate Probability of a Diagnosis: A Randomized Clinical Trial

This randomized clinical trial evaluates whether medical students can be taught to make more accurate bayesian revisions of diagnostic probabilities using learning by concept or learning by example.

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JAMA Netw Open. 2019;2(12):e1918023. doi:10.1001/jamanetworkopen.2019.18023
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Assessment of Physician Self-reported Knowledge and Use of Maryland’s Extreme Risk Protection Order Law

This survey study assesses Maryland physicians’ knowledge, past use, and likely future use of extreme risk protection orders, barriers to their use, and strategies to address those barriers.

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JAMA Netw Open. 2019;2(12):e1918037. doi:10.1001/jamanetworkopen.2019.18037
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ALLERGY

Determining Levers of Cost-effectiveness for Screening Infants at High Risk for Peanut Sensitization Before Early Peanut Introduction

This economic evaluation identifies scenarios in which the current US guidelines for early introduction of peanut to infants would be cost-effective.

JAMA Netw Open. 2019;2(12):e1918041. doi:10.1001/jamanetworkopen.2019.18041
Abstract Full Text pdf link PDF

PEDIATRICS

Effect of Parental Counseling on Infants’ Healthy Sleep Habits in Brazil: A Randomized Clinical Trial

This randomized clinical trial examines the effect of parental counseling on bedtime routines and behaviors on infants’ sleep habits from ages 3 months to 2 years.

JAMA Netw Open. 2019;2(12):e1918062. doi:10.1001/jamanetworkopen.2019.18062
Abstract Full Text pdf link PDF

ONCOLOGY

Effect of Concurrent Chemoradiation With Celecoxib vs Concurrent Chemoradiation Alone on Survival Among Patients With Non–Small Cell Lung Cancer With and Without Cyclooxygenase 2 Genetic Variants: A Phase 2 Randomized Clinical Trial

This phase 2 randomized clinical trial evaluates the effect of combined selective cyclooxygenase 2 (COX-2) inhibition with standard concurrent chemoradiation therapy vs concurrent chemoradiation alone on survival among patients with unresectable stage III non–small cell lung cancer (NSCLC).

JAMA Netw Open. 2019;2(12):e1918070. doi:10.1001/jamanetworkopen.2019.18070
Abstract Full Text pdf link PDF

GENETICS AND GENOMICS

Single-Nucleotide Polymorphism–Based Genetic Risk Score and Patient Age at Prostate Cancer Diagnosis

This cohort study examines the association between a single-nucleotide polymorphism (SNP)–based genetic risk score and patient age at prostate cancer diagnosis and compares the performance of the genetic risk score with that of family history in prostate cancer risk stratification.

JAMA Netw Open. 2019;2(12):e1918145. doi:10.1001/jamanetworkopen.2019.18145
Abstract Full Text pdf link PDF

NEPHROLOGY

Clinical Characteristics of and Risk Factors for Chronic Kidney Disease Among Adults and Children: An Analysis of the CURE-CKD Registry

This cohort study examines the clinical features of, prevalence of, major risk factors for, and care for chronic kidney disease among adults and children treated in 2 large US health care systems.

JAMA Netw Open. 2019;2(12):e1918169. doi:10.1001/jamanetworkopen.2019.18169
Abstract Full Text pdf link PDF

NEUROLOGY

Comparison of Lemborexant With Placebo and Zolpidem Tartrate Extended Release for the Treatment of Older Adults With Insomnia Disorder: A Phase 3 Randomized Clinical Trial

This randomized clinical trial examines the effectiveness of treatment with lemborexant therapy compared with placebo and with zolpidem tartrate extended release therapy in adults 55 years and older with insomnia disorder.

JAMA Netw Open. 2019;2(12):e1918254. doi:10.1001/jamanetworkopen.2019.18254
Abstract Full Text pdf link PDF

PEDIATRICS

Association Between Objectively Measured Sleep Duration and Symptoms of Psychiatric Disorders in Middle Childhood

This population-based cohort study examines whether sleep duration is associated with the development of emotional and behavioral problems in school-aged children in Norway.

JAMA Netw Open. 2019;2(12):e1918281. doi:10.1001/jamanetworkopen.2019.18281
Abstract Full Text pdf link PDF

HEALTH INFORMATICS

Primary Care Physicians’ Experiences With and Strategies for Managing Electronic Messages

This qualitative study conducted in a large group practice examines primary care physicians’ experiences managing their electronic message inboxes and describes the management strategies developed by individual physicians and practice groups.

JAMA Netw Open. 2019;2(12):e1918287. doi:10.1001/jamanetworkopen.2019.18287
Abstract Full Text pdf link PDF

PEDIATRICS

Association of a Targeted Population Health Management Intervention with Hospital Admissions and Bed-Days for Medicaid-Enrolled Children

This quality improvement study estimates the association of a targeted population health management intervention for children eligible for Medicaid with changes in monthly hospital admissions and bed-days.

JAMA Netw Open. 2019;2(12):e1918306. doi:10.1001/jamanetworkopen.2019.18306
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

Risk Factors and Mortality Rates Associated With Invasive Group B Streptococcus Infections Among Patients in the US Veterans Health Administration

This cohort study investigates risk factors and mortality rates associated with specific invasive group B Streptococcus infectious syndromes among patients of the Veterans Affairs health care system.

JAMA Netw Open. 2019;2(12):e1918324. doi:10.1001/jamanetworkopen.2019.18324
Abstract Full Text pdf link PDF

SUBSTANCE USE AND ADDICTION

Association of State Opioid Duration Limits With Postoperative Opioid Prescribing

This interrupted time series analysis and cross-sectional study investigates the association of opioid prescribing duration limits with postoperative opioid prescribing in Massachusetts and Connecticut.

JAMA Netw Open. 2019;2(12):e1918361. doi:10.1001/jamanetworkopen.2019.18361
Abstract Full Text pdf link PDF

CARDIOLOGY

Magnitude of and Characteristics Associated With the Treatment of Calcium Channel Blocker–Induced Lower-Extremity Edema With Loop Diuretics

This cohort study used prescription sequence symmetry analysis to assess the magnitude and characteristics of the prescribing cascade of treating dihydropyridine calcium channel blocker–induced lower-extremity edema with loop diuretics.

JAMA Netw Open. 2019;2(12):e1918425. doi:10.1001/jamanetworkopen.2019.18425
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HEALTH POLICY

Association of Mandatory Bundled Payments for Joint Replacement With Use of Postacute Care Among Medicare Advantage Enrollees

This cohort study determines the association of bundled payments for joint replacement surgical procedures with the use of postacute care services among patients enrolled in Medicare Advantage.

JAMA Netw Open. 2019;2(12):e1918535. doi:10.1001/jamanetworkopen.2019.18535
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open access Editorial

Screening for Abdominal Aortic Aneurysm—A Call to Arms?

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JAMA Netw Open. 2019;2(12):e1917168. doi:10.1001/jamanetworkopen.2019.17168
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open access Invited Commentary

COMPLEMENTARY AND ALTERNATIVE MEDICINE

Acupuncture—A Question of Culture

JAMA Netw Open. 2019;2(12):e1916929. doi:10.1001/jamanetworkopen.2019.16929
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ONCOLOGY

Biomarker-Driven Staging—Are We There Yet?

JAMA Netw Open. 2019;2(12):e1917052. doi:10.1001/jamanetworkopen.2019.17052
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RHEUMATOLOGY

Which Patients With Rheumatoid Arthritis Will Start Biologics, How Soon, and Why—Much to Learn From a Universal Coverage Setting

JAMA Netw Open. 2019;2(12):e1917065. doi:10.1001/jamanetworkopen.2019.17065
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HEALTH INFORMATICS

Making Machine Learning Accessible and Actionable for Clinicians

JAMA Netw Open. 2019;2(12):e1917362. doi:10.1001/jamanetworkopen.2019.17362
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INFECTIOUS DISEASES

The High Burden of Sexually Transmitted Infections in Persons Initiating Preexposure Prophylaxis—Challenge or Opportunity?

JAMA Netw Open. 2019;2(12):e1917482. doi:10.1001/jamanetworkopen.2019.17482
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PSYCHIATRY

In Search of Historical Insight Into the Problem of Military Suicide

JAMA Netw Open. 2019;2(12):e1917498. doi:10.1001/jamanetworkopen.2019.17498
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STATISTICS AND RESEARCH METHODS

Improved Reporting in Abstracts When Uncertainty Is Inevitable

JAMA Netw Open. 2019;2(12):e1917543. doi:10.1001/jamanetworkopen.2019.17543
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HEALTH POLICY

In Pursuit of Meaningful Performance Measures for Postacute Care

JAMA Netw Open. 2019;2(12):e1917558. doi:10.1001/jamanetworkopen.2019.17558
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ENVIRONMENTAL HEALTH

Emerging Insights Into the Association Between Nature Exposure and Healthy Neuronal Development

JAMA Netw Open. 2019;2(12):e1917880. doi:10.1001/jamanetworkopen.2019.17880
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MEDICAL EDUCATION

The Pursuit of Diagnostic Excellence

JAMA Netw Open. 2019;2(12):e1918040. doi:10.1001/jamanetworkopen.2019.18040
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PEDIATRICS

An Educational Intervention for Improving Infant Sleep Duration—Why Won’t You Sleep, Baby?

JAMA Netw Open. 2019;2(12):e1918061. doi:10.1001/jamanetworkopen.2019.18061
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NEUROLOGY

Pharmacotherapy for Insomnia Disorder in Older Adults

JAMA Netw Open. 2019;2(12):e1918214. doi:10.1001/jamanetworkopen.2019.18214
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PUBLIC HEALTH

On the Opinions of US Adults Regarding Religiously Affiliated Health Care Facilities

JAMA Netw Open. 2019;2(12):e1919013. doi:10.1001/jamanetworkopen.2019.19013
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open access Research Letter

HEMATOLOGY

Hypertension in Patients Treated With Ibrutinib for Chronic Lymphocytic Leukemia

This cohort study describes patterns of development, management strategies, and long-term vascular consequences of hypertension associated with ibrutinib in the non–clinical trial setting.

JAMA Netw Open. 2019;2(12):e1916326. doi:10.1001/jamanetworkopen.2019.16326
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HEALTH POLICY

Availability of Grocery Delivery to Food Deserts in States Participating in the Online Purchase Pilot

This cross-sectional study examines the availability of grocery delivery in census tracts designated as food deserts and among households within them.

JAMA Netw Open. 2019;2(12):e1916444. doi:10.1001/jamanetworkopen.2019.16444
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HEALTH INFORMATICS

Evaluating Improvements and Shortcomings in Clinician Satisfaction With Electronic Health Record Usability

This cross-sectional study compares reported 2015 system usability scale scores for electronic health record systems with 2014 scores and with benchmarks to evaluate whether satisfaction is improving.

JAMA Netw Open. 2019;2(12):e1916651. doi:10.1001/jamanetworkopen.2019.16651
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OBSTETRICS AND GYNECOLOGY

Racial Disparities in Route of Hysterectomy for Benign Indications Within an Integrated Health Care System

This cross-sectional study examines racial disparities in the route of hysterectomy for benign indications within an integrated health care system in the United States.

JAMA Netw Open. 2019;2(12):e1917004. doi:10.1001/jamanetworkopen.2019.17004
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HEALTH POLICY

Trends in List Prices, Net Prices, and Discounts for Originator Biologics Facing Biosimilar Competition

In this cohort study, pricing data from January 2007 to June 2018 from SSR Health were used to determine how list prices, net prices, and discounts for the originator biologics changed with biosimilar competition.

JAMA Netw Open. 2019;2(12):e1917379. doi:10.1001/jamanetworkopen.2019.17379
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PUBLIC HEALTH

Trends in Mental and Physical Health-Related Quality of Life in Low-Income Older Persons in the United States, 2003 to 2017

This cross-sectional study of respondents to the Behavioral Risk Factor Surveillance System survey assesses trends between 2003 and 2017 in mental and physical health-related quality of life in low-income US individuals 60 years or older.

JAMA Netw Open. 2019;2(12):e1917868. doi:10.1001/jamanetworkopen.2019.17868
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PUBLIC HEALTH

Assessment of Tanning Beds in 3 Popular Gym Chains

This cross-sectional study examines the proportion of gyms from 3 large national chains in the United States that offer tanning services, the number of tanning beds offered by these gyms, and regional differences in the number of gyms that provide tanning services.

JAMA Netw Open. 2019;2(12):e1918058. doi:10.1001/jamanetworkopen.2019.18058
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CARDIOLOGY

Atherosclerosis in 16th-Century Greenlandic Inuit Mummies

This case series examines 4 Greenlandic Inuit mummies from approximately the 16th century for evidence of atherosclerosis.

JAMA Netw Open. 2019;2(12):e1918270. doi:10.1001/jamanetworkopen.2019.18270
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HEALTH INFORMATICS

Association of Use of Online Symptom Checkers With Patients’ Plans for Seeking Care

This cross-sectional study examines the association of patient use of a free online symptom checker tool with patient plans for seeking medical care.

JAMA Netw Open. 2019;2(12):e1918561. doi:10.1001/jamanetworkopen.2019.18561
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INFECTIOUS DISEASES

Prevalence of Human Papillomavirus Infection by Number of Vaccine Doses Among US Women

This cross-sectional study investigates the prevalence of human papillomavirus (HPV) infection among US women who received between 0 and 3 doses of HPV vaccine.

JAMA Netw Open. 2019;2(12):e1918571. doi:10.1001/jamanetworkopen.2019.18571
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open access Correction

Error in Author Affiliations

JAMA Netw Open. 2019;2(12):e1918528. doi:10.1001/jamanetworkopen.2019.18528
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Error in Title and Table

JAMA Netw Open. 2019;2(12):e1919047. doi:10.1001/jamanetworkopen.2019.19047
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Error in Table Notes

JAMA Netw Open. 2019;2(12):e1919372. doi:10.1001/jamanetworkopen.2019.19372
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Error in Author’s Academic Degree

JAMA Netw Open. 2019;2(12):e1919971. doi:10.1001/jamanetworkopen.2019.19971
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open access JAMA Network Open Masthead

JAMA Network Open

JAMA Netw Open. 2019;2(12):e1917150. doi:10.1001/jamanetworkopen.2019.17150
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