This cohort study determines the trajectory of β-amyloid accumulation among patients with probable dementia with Lewy bodies and investigates the associations of β-amyloid accumulation with measures of clinical and cognitive decline over time in dementia with Lewy bodies.
This cohort study investigates changes in cause-specific outcomes and trends associated with type 2 diabetes among individuals with incident heart failure in the United Kingdom from 1998 to 2017.
This cohort study assesses the rate and timing of urologic procedures performed after an emergency department visit for renal colic and the factors associated with receipt of an intervention within 60 days.
This cohort study determines whether a simple visual aid is associated with a reduction in duplicate ordering of tests and medications in an emergency department.
This economic evaluation compares the cost-effectiveness of finger replantation vs revision amputation after traumatic finger amputation.
This cross-sectional study compares direct-to-physician commercial promotion of medications for opioid use disorder in rural vs urban county locations.
This cohort study assesses whether lymphopenia is associated with reduced survival among outpatients enrolled in the US National Health and Nutrition Examination Survey.
This systematic review and qualitative analysis examines the health system barriers to and facilitators of care for noncommunicable diseases by nonphysician health workers in low- and middle-income countries.
This cohort study examines the association between depressive symptoms and incident cardiovascular disease among middle-aged and older Chinese adults.
This secondary analysis of the TOPCAT randomized clinical trial examines the association of β-blocker use with heart failure (HF) hospitalizations and cardiovascular disease (CVD) mortality, overall and in strata of patients with an ejection fraction (EF) of 50% or greater or less than 50%.
This cohort study examines the association of dietary patterns in midlife with cognitive function in later life in US adults without dementia at baseline.
This cohort study examines the difference in improvement of functional status among patients with stroke who received postacute care in inpatient rehabilitation vs skilled nursing facilities.
This cohort study analyzes the association between participation in the Women, Infants, and Children (WIC) program and birth outcomes among low-income pregnant women in the United States by gestational age at birth and maternal race/ethnicity.
This cohort study uses data from the Prostate, Lung, Colorectal, and Ovarian Cancer Screen Trial to examine the associations among regular aspirin use, obesity, and all-cause and cancer mortality among older adults.
This cohort study examines rehospitalization factors, hospitalization and mortality, discharge disposition, and the changes in these variables over time among all adult patients in the Kaiser Permanente Northern California health system.
This cohort study investigates the associations between periconception paternal body mass index (BMI) and DNA methylation patterns in offspring.
This cross-sectional study examines the association between electronic cigarette (e-cigarette) use and depression in a nationally representative sample of the adult population in the United States.
This randomized clinical trial examines the efficacy of true or sham acupuncture vs standard care in the treatment of radiation-induced xerostomia among patients in the United States and China.
This prognostic study evaluates the addition of preoperative and intraoperative data to prehospitalization data to identify patients at risk for postoperative acute kidney injury after undergoing major noncardiac surgery.
This diagnostic study establishes and assesses models to detect diffuse glioma and to differentiate glioblastoma, primary central nervous system lymphoma, and metastatic brain tumors.
This prognostic study assesses whether preoperative computed tomographic findings can be used for sigmoid colon cancer prognosis.
This cohort study examines the association of blunt use with cigar use among US adolescents.
This population-based survey study examines patient views on religious institutional care, specifically whether they consider religious affiliation when selecting a health care facility and whether they believe that their personal choices about their health should take priority over a facility’s religious values.
This cohort study characterizes current practice and trends among patients cared for and outcomes achieved by inpatient specialty palliative care services in the United States.
This cohort study evaluates the associations of patient, prescriber, and geographic region with differences in time to first prescription of biologic disease-modifying antirheumatic drug among older adults with rheumatoid arthritis and identical health insurance coverage in Ontario, Canada.
This cohort study examines whether incorporation of a molecular prognostic classifier into conventional TNM staging for non–small cell lung cancer improves estimation of disease-free survival.
This randomized clinical trial assesses the effectiveness of a computerized decision support system that preappraises evidence and provides health professionals with actionable, patient-specific recommendations at the point of care.
This cohort study of participants with dominantly inherited Alzheimer disease examines the rates of change in cerebrospinal fluid levels of total tau (tTau) and phosphorylated tau 181 (pTau181) across the disease course and how the rates of change are associated with brain atrophy.
This systematic review and meta-analysis estimates the prevalence of sexually transmitted infections at initiation of HIV preexposure prophylaxis (PrEP) and the incidence of sexually transmitted infections during use of HIV PrEP.
This cohort study analyzes the association between testosterone and opioid use and improved health outcomes among male US military veterans with opioid-induced androgen deficiency.
This prognostic study develops and validates the performance of a neural network machine learning model compared with a model based on median length of stay for predicting which patients are likely to be discharged within 24 hours from inpatient surgical care and their barriers to discharge.
This cross-sectional study uses data from the National Health and Nutrition Examination Study to evaluate trends in prescription opioid use and nonopioid analgesic use from 1999 to 2016 among US adults with functional limitations attributable to musculoskeletal conditions.
This cross-sectional study determines the incidence of and risk factors associated with severe acute kidney injury (AKI) and AKI requiring dialysis after gunshot wounds and the association of severe AKI and AKI requiring dialysis with mortality among civilians in the United States.
This cross-sectional study examines the associations of aging and modifiable risk factors for dementia with volume differences in brain regions known to be associated with Alzheimer disease and whether these volume differences are associated with cognitive performance.
This cross-sectional study estimates time trends and geographical variations in rates of arthroscopic surgery among US states and investigates whether rates of arthroscopy are associated with geographic density of orthopedists.
This cohort study describes the structures, processes, and variability of end-of-life care delivered in intensive care units in the United States.
This case-control study compares cerebrospinal fluid (CSF) amyloid and tau biomarkers for Alzheimer disease in African American and white individuals with normal cognition and with mild cognitive impairment.
This population-based cohort study investigates the association of adult weight gain with major health outcomes in middle-aged Chinese persons who had low body weight in early adulthood.
This quality improvement study examines the accuracy and user experience of a cost estimator tool delivered via an online patient portal and informed by real-time data from third-party payers.
This cross-sectional study consolidates data on suicides among active-duty personnel in the US Army from 1819 to 2017 and identifies historical trends to separate them from more acute causal factors.
This systematic review and meta-analysis examines the expression of uncertainty in abstracts of published oncology randomized clinical trials.
This cohort study of community-dwelling survivors of the 2011 Great East Japan Earthquake and Tsunami assesses whether postdisaster depression and posttraumatic stress disorder are associated with mortality.
This cohort study examines the differences between 2 Centers for Medicare & Medicaid Services measures for 30-day rehospitalization after discharge from postacute inpatient rehabilitation.
This cohort study examines the association of suicide and other mortality risk within 1 year of emergency department presentation among patients presenting with deliberate self-harm, suicidal ideation, or any other chief concern.
This cohort study compares the risk of operative and nonoperative interventions up to 4 years after Roux-en-Y gastric bypass vs vertical sleeve gastrectomy in patient groups matched on US region, year of surgery, body mass index category, and type 2 diabetes status.
This cohort study examines the incidence of sport-related and non–sport-related concussions among US undergraduate college students and varsity athletes stratified by sex and cause of concussion.
This birth cohort study examines the association between prenatal and perinatal exposures to fine particulate matter (diameter <2.5 μm) and changes in hemoglobin A1c levels in children aged 4 to 6 years.
This cohort study compares antiretroviral prescribing practices over time among pregnant women living with HIV with US Department of Health and Human Services treatment guidelines.
This randomized clinical trial examines whether computer-automated screening and clinical decision support can improve autism spectrum disorder screening rates in a pediatric primary care practice.
This systematic review and meta-analysis assesses the risk of fracture associated with differences in concentrations of 25-hydroxyvitamin D (25[OH]D) in observational studies and the effects of supplementation with vitamin D alone or in combination with calcium on fracture in randomized clinical trials.
This cross-sectional study evaluates the association between greenness surrounding schools or kindergartens and symptoms of attention-deficit/hyperactivity disorder among Chinese children.
This cross-sectional study evaluates the prevalence and characteristics of US adults who are unaware of the symptoms of and appropriate response to myocardial infarction.
This randomized clinical trial examines whether a motivational interviewing–based intervention increases linkage of adolescents to outpatient mental health services and reduces depression symptoms and suicidal ideation in adolescents seeking emergency care for non–mental health–related concerns.
This cohort study examines the associations of colorectal cancer screening and modalities with colorectal cancer incidence and mortality by race and socioeconomic status among southern US adults.
This cross-sectional bibliometric analysis identifies top-cited articles on obstetrics and gynecology topics and compares top-cited articles published in obstetrics and gynecology specialty journals with those published in general medical journals.
This randomized clinical trial evaluates whether medical students can be taught to make more accurate bayesian revisions of diagnostic probabilities using learning by concept or learning by example.
This survey study assesses Maryland physicians’ knowledge, past use, and likely future use of extreme risk protection orders, barriers to their use, and strategies to address those barriers.
This economic evaluation identifies scenarios in which the current US guidelines for early introduction of peanut to infants would be cost-effective.
This randomized clinical trial examines the effect of parental counseling on bedtime routines and behaviors on infants’ sleep habits from ages 3 months to 2 years.
This phase 2 randomized clinical trial evaluates the effect of combined selective cyclooxygenase 2 (COX-2) inhibition with standard concurrent chemoradiation therapy vs concurrent chemoradiation alone on survival among patients with unresectable stage III non–small cell lung cancer (NSCLC).
This cohort study examines the association between a single-nucleotide polymorphism (SNP)–based genetic risk score and patient age at prostate cancer diagnosis and compares the performance of the genetic risk score with that of family history in prostate cancer risk stratification.
This cohort study examines the clinical features of, prevalence of, major risk factors for, and care for chronic kidney disease among adults and children treated in 2 large US health care systems.
This randomized clinical trial examines the effectiveness of treatment with lemborexant therapy compared with placebo and with zolpidem tartrate extended release therapy in adults 55 years and older with insomnia disorder.
This population-based cohort study examines whether sleep duration is associated with the development of emotional and behavioral problems in school-aged children in Norway.
This qualitative study conducted in a large group practice examines primary care physicians’ experiences managing their electronic message inboxes and describes the management strategies developed by individual physicians and practice groups.
This quality improvement study estimates the association of a targeted population health management intervention for children eligible for Medicaid with changes in monthly hospital admissions and bed-days.
This cohort study investigates risk factors and mortality rates associated with specific invasive group B Streptococcus infectious syndromes among patients of the Veterans Affairs health care system.
This interrupted time series analysis and cross-sectional study investigates the association of opioid prescribing duration limits with postoperative opioid prescribing in Massachusetts and Connecticut.
This cohort study used prescription sequence symmetry analysis to assess the magnitude and characteristics of the prescribing cascade of treating dihydropyridine calcium channel blocker–induced lower-extremity edema with loop diuretics.
This cohort study determines the association of bundled payments for joint replacement surgical procedures with the use of postacute care services among patients enrolled in Medicare Advantage.
This cohort study describes patterns of development, management strategies, and long-term vascular consequences of hypertension associated with ibrutinib in the non–clinical trial setting.
This cross-sectional study examines the availability of grocery delivery in census tracts designated as food deserts and among households within them.
This cross-sectional study compares reported 2015 system usability scale scores for electronic health record systems with 2014 scores and with benchmarks to evaluate whether satisfaction is improving.
This cross-sectional study examines racial disparities in the route of hysterectomy for benign indications within an integrated health care system in the United States.
In this cohort study, pricing data from January 2007 to June 2018 from SSR Health were used to determine how list prices, net prices, and discounts for the originator biologics changed with biosimilar competition.
This cross-sectional study of respondents to the Behavioral Risk Factor Surveillance System survey assesses trends between 2003 and 2017 in mental and physical health-related quality of life in low-income US individuals 60 years or older.
This cross-sectional study examines the proportion of gyms from 3 large national chains in the United States that offer tanning services, the number of tanning beds offered by these gyms, and regional differences in the number of gyms that provide tanning services.
This case series examines 4 Greenlandic Inuit mummies from approximately the 16th century for evidence of atherosclerosis.
This cross-sectional study examines the association of patient use of a free online symptom checker tool with patient plans for seeking medical care.
This cross-sectional study investigates the prevalence of human papillomavirus (HPV) infection among US women who received between 0 and 3 doses of HPV vaccine.
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