This cross-sectional study of pregnancies among women in the Kaiser Permanente Northern California health care system examines trends in daily, weekly, and monthly self-reported cannabis use in the year before and during pregnancy from 2009 to 2017.
This cohort study estimates the risk of 30-day hospital readmission among adults receiving autologous and allogenic hematopoietic cell transplants in the United States.
This cross-sectional study examines changes in revenues of manufacturers of drugs for treatment of hepatitis C and health care organizations after list price reductions.
This data review and cross-sectional study assesses how health care professionals associate men and women with career and family and how surgeons associate men and women with surgery and family medicine.
This cohort study uses data from the Surveillance, Epidemiology, and End Results (SEER)–Medicare database to investigate the association between androgen deprivation therapy and diagnosis of Alzheimer disease or dementia among elderly men with prostate cancer.
This randomized clinical trial of adults overdue for colorectal cancer screening examines whether financial incentives conditional on completion of colorectal cancer screening increase screening uptake.
This population-based cohort study compares long-term outcomes of elective endovascular aortic repair vs open surgical repair of abdominal aortic aneurysm among patients 40 years and older in Ontario, Canada.
This cross-sectional study investigates changes in perceptions of discrimination in health care on the basis of race/ethnicity, immigration status, and English proficiency in California from 2003 to 2017.
This case-control study describes the development and validation of a risk score, the Stopping Opioids After Surgery Score, for sustained prescription opioid use after surgery in a population of patients participating in a US Department of Defense insurance program.
This cross-sectional study uses machine reading to estimate the magnitude of female underrepresentation in clinical studies worldwide.
This prognostic study develops and validates a multivariable prediction model for assessing inpatient violence risk, using machine learning techniques applied to clinical notes written in patients’ electronic health records.
This cohort study identifies processes of care that are associated with reduced risk of death or recurrent stroke among patients with transient ischemic attack or nonsevere ischemic stroke.
This cohort study evaluates the risk of developing cancer from birth to age 41 years among patients with congenital heart disease compared with healthy matched controls in Sweden.
This cohort study examines whether implementation of a traffic light–labeling and choice architecture program in a hospital workplace cafeteria is associated with reduction in calories purchased by employees over 2 years.
This cross-sectional study examines US Medicare data to assess variations in health care costs and utilization between accountable care organization practices that rely heavily on specialty physicians and those that only use primary care physicians.
This study of 100 randomized clinical trials determines how frequently immune checkpoint inhibitor (ICI) and non-ICI anticancer agents displayed trends of long-term durable survival as defined by the American Society of Clinical Oncology (ASCO) Value Framework and the European Society of Medical Oncology (ESMO) Magnitude of Clinical Benefit Scale.
This comparative effectiveness study of a nationwide clinical registry of percutaneous coronary intervention (PCI) determines whether machine learning techniques better predict post-PCI major bleeding compared with the existing National Cardiovascular Data Registry (NCDR) models.
This survey study evaluates the association between subjective well-being and life expectancy free of disability and chronic disease in older adults in England.
This meta-analysis examines whether differences in biomarkers, such as programmed cell death ligand 1 (PD-L1) expression and tumor mutation burden, are associated with improved response to immunotherapy and survival in patients with advanced non–small cell lung cancer (NSCLC).
This qualitative study examines the perspectives of representatives of US Medicare Advantage plans on how their organizations can enact programs to promote social determinants of health in light of expansions offered under the Creating High-Quality Results and Outcomes Necessary to Improve Chronic (CHRONIC) Care Act.
This survey study of Michigan primary care clinics assesses practitioner willingness to accept and continue prescribing opioids to new patients with pain and whether this willingness differs across payer types.
This cross-sectional study assesses the reach of court-ordered antismoking advertisements among the US adult population, stratified by demographic characteristics and tobacco use.
This cross-sectional study uses data from the US National Survey of Accountable Care Organizations to assess the association between accountable care organization–reported care management and coordination activities and outcomes in older adults with complex needs.
This qualitative study uses narrative analysis of interviews with emerging adults, aged 18 to 24 years, with type 1 diabetes to identify distinct story types that describe participants’ perceptions of living with type 1 diabetes.
This systematic review and meta-analysis investigates the association between preterm birth or low birth weight and social relationships in adulthood.
This cohort study develops and validates a deep learning algorithm using longitudinal electronic health records to predict mortality risk as a proxy indicator for identifying patients with dementia who may benefit from palliative care.
This systematic review and meta-analysis examines the cognitive and motor development of infants and children exposed to opioids prenatally.
This national population-based study uses a quasi-experimental design to assess the association between preterm births among US Latina mothers and the 2016 US presidential election.
This cohort study compares therapeutic inertia, the failure to escalate therapy when goals are unmet, among neurologists across 4 countries (Canada, Argentina, Chile, and Spain) and identifies factors contributing to therapeutic inertia.
This secondary analysis of the 35th Multicenter Airway Research Collaboration cohort study investigates whether serum albumin levels are associated with apnea in infants hospitalized for bronchiolitis.
This cross-sectional analysis of data from more than 2.5 million Medicaid-eligible US adults in states that enacted and did not enact Medicaid expansion under the Patient Protection and Affordable Care Act evaluates the association of Medicaid expansion with health insurance coverage among persons with a disability.
This quality improvement study examines whether over-the-counter medication dispensing behavior in Australian pharmacies complies or conflicts with the protocols indicated in practice standards and guidelines of a national professional pharmacy organization.
This cross-sectional study estimates the number and characteristics of Medicaid beneficiaries in Kentucky who would have to meet community engagement requirements under a Section 1115 Medicaid demonstration waiver.
This cross-sectional study uses data from the US National Survey on Drug Use and Health to estimate changes in nonmedical prescription opioid use and prescription opioid use disorder in states that have legalized the use of medical marijuana.
This cohort study evaluates the prevalence and risk factors of long-term opioid use after injury among workers in Tennessee who were opioid free at the time of injury.
This systematic review and meta-analysis examines the association of interventions used to improve decision-making by surrogates of patients in intensive care units with patient- and family-centered outcomes and resource use.
This cohort study uses data from more than 265 000 US veterans treated at Veterans Affairs Medical Centers (VAMCs) to compare health care spending for patients with chronic heart failure across VAMCs and to examine the association between spending and survival.
This cross-sectional study examines the status of randomized clinical trials (RCTs) whose primary outcome changed between trial registration and publication and quantifies the association of this change with the reported intervention effect size.
This cohort study evaluates trends of medical imaging, including computed tomography, magnetic resonance imaging, angiography and fluoroscopy, and nuclear medicine, among pregnant women in the United States and Ontario, Canada.
This cross-sectional study examines the value of nonculture cerebrospinal fluid (CSF) testing in immune-competent children with normal CSF cell count.
This comparative effectiveness study examines current US Centers for Medicare & Medicaid Services 30-day mortality risk models vs novel risk models for acute myocardial infarction, heart failure, and pneumonia hospitalizations.
This cohort study uses data from women enrolled in the Women’s Health Initiative (WHI) to examine the associations of normal-weight central obesity with all-cause and cause-specific mortality among postmenopausal women in the United States.
This prognostic study develops and tests a convoluted neural network (CXR-risk) to predict long-term mortality from chest radiographs.
This cross-sectional study investigates spending by the US National Institutes of Health (NIH) for studies focusing on Asian American, Native Hawaiian, and Pacific Islander populations.
This cohort study uses data from the CAC Consortium to examine the prevalence of coronary artery calcium in young adults and the subsequent association of coronary artery calcium with coronary heart disease, cardiovascular disease, and all-cause mortality.
This study evaluates survey responses from a large national cohort of US resident physicians to assess the association between burnout and explicit and implicit racial biases among nonblack resident physicians.
This before-after quality improvement study evaluates whether a multifactorial intervention was associated with a reduction in the volume of laboratory tests ordered by clinicians in the internal medicine departments of teaching hospitals in the Netherlands.
This cohort study compares 30-day mortality and inpatient intensive care unit (ICU) admissions before and after the implementation of a novel emergency department–based ICU.
This systematic review analyzes data from surveys conducted as part of community consultation to assess levels of public approval of trials conducted with an exception from informed consent.
This cross-sectional study examines the current status and secular trends in physical activity and sedentary behavior among US adults using data from the National Health and Nutrition Examination Survey (NHANES) from 2007 to 2016.
This cross-sectional study assesses variation in 30-day unplanned hospital readmission rates among adolescents and young adults with complex chronic disease as they advance in age.
This cohort study evaluates the association of serological biomarkers with the response to immune checkpoint blockade therapy in patients with metastatic gastrointestinal tract cancer.
This cohort study compares the location of death and measures of health care use in the last 6 months of life for physicians vs nonphysicians in Canada.
This single-institution diagnostic study uses a machine learning method (morphological-based molecular profiling) to assess the prediction feasibility of molecular expression of biomarkers in cancer tissue of patients with breast cancer.
This cohort study examines the use of antipsychotic medication in youths, aged 3 to 24 years, following a new diagnosis of attention-deficit/hyperactivity disorder.
This cohort study analyzes economic, community, and hospital factors associated with the adoption of stroke center certification for US hospitals from 2009 to 2017.
This cohort study uses US national insurance claims data from a single private payer to assess the association between opioid prescribing before and after vaginal or cesarean delivery and the rates of new persistent opioid use among these women.
This study used Bayesian network meta-analyses to assess the magnitude of association of interventions provided to pregnant women, infants, and young children with child development birth and growth outcomes based on randomized clinical trials conducted in low-income and middle-income countries (LMICs).
This cohort study examines whether liver function markers are associated with cognitive dysfunction and the amyloid, tau, and neurodegeneration biomarkers in individuals with Alzheimer disease.
This cohort study, using data from the UK Biobank and health surveys in England and Scotland, compares the relative utility of cause of death data extracted from the underlying cause field vs any location on the death certificate.
This cohort study examines the association of preoperative opioid use with mortality and safety outcomes after total knee replacement in patients 65 years and older.
This quality improvement study uses a novel taxonomy to analyze the associations of human performance deficiencies with surgical adverse events.
This cohort study analyzes Canadian cancer incidence registries to determine incidence trends for colorectal cancer among older and younger adults.
This prespecified subgroup analysis of the China Antihypertensive Trial in Acute Ischemic Stroke (CATIS) randomized clinical trial evaluates the association between immediate antihypertensive treatment and patient outcomes among patients with acute ischemic stroke with vs without a history of hypertension.
This population-based cohort study investigates the association of hearing loss with incident dementia among Taiwanese adults in the general population.
This systematic review and network meta-analysis compares and ranks different therapeutic strategies to identify the best intervention associated with a reduction in mortality in adult patients with moderate to severe acute respiratory distress syndrome (ARDS).
This cohort study examines the association between neonatal neuroimaging findings and clinical outcomes in infants exposed to Zika virus in utero in Brazil.
This randomized clinical trial examines whether an enhanced medical rehabilitation intervention, a systematic approach for physical and occupational therapy to engage patients, improves functional recovery in older patients receiving skilled nursing care after acute rehabilitation.
This cohort study assesses whether urban green space, tree canopy, grass, and other low-lying vegetation are associated with better mental health among Australian adults.
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