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September 2021 - May 2018

Decade

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Issue

October 2020, Vol 3, No. 10

open access Original Investigation

ANESTHESIOLOGY

Effect of Tropisetron on Prevention of Emergence Delirium in Patients After Noncardiac Surgery: A Trial Protocol

This trial protocol describes a randomized clinical trial that aims to determine the efficacy and safety of tropisetron for prevention of emergence delirium in patients undergoing noncardiac surgery.

JAMA Netw Open. 2020;3(10):e2013443. doi:10.1001/jamanetworkopen.2020.13443
Abstract Full Text pdf link PDF

ONCOLOGY

Safety, Antitumor Activity, and Pharmacokinetics of Toripalimab, a Programmed Cell Death 1 Inhibitor, in Patients With Advanced Non–Small Cell Lung Cancer: A Phase 1 Trial

This phase 1 trial assesses the safety, antitumor activity, and pharmacokinetics of toripalimab in patients with advanced non–small cell lung cancer (NSCLC) and evaluates the utility of JS311, a novel programmed death cell ligand 1 immunohistochemistry assay.

JAMA Netw Open. 2020;3(10):e2013770. doi:10.1001/jamanetworkopen.2020.13770
Abstract Full Text pdf link PDF

ONCOLOGY

Assessment of Secondary Sarcomas Among Patients With Cancer of the Abdomen or Pelvis Who Received Combinations of Surgery, Radiation, and Chemotherapy vs Surgery Alone

This cohort study compares the risk of secondary sarcoma among patients treated with combinations of surgery, radiation, and chemotherapy with patients treated with surgery alone and with the general population.

JAMA Netw Open. 2020;3(10):e2013929. doi:10.1001/jamanetworkopen.2020.13929
Abstract Full Text pdf link PDF

ONCOLOGY

Prediction of Overall Survival Among Female Patients With Breast Cancer Using a Prognostic Signature Based on 8 DNA Repair–Related Genes

This prognostic study evaluates a potential DNA repair–related prognostic signature to improve the accuracy of prediction of the overall survival of patients with breast cancer.

JAMA Netw Open. 2020;3(10):e2014622. doi:10.1001/jamanetworkopen.2020.14622
Abstract Full Text pdf link PDF

NEUROLOGY

Assessment of Use and Safety of Edaravone for Amyotrophic Lateral Sclerosis in the Veterans Affairs Health Care System

This cohort study uses real-world data to assess patient characteristics and use as well as the safety and effectiveness of edaravone among patients with amyotrophic lateral sclerosis in the US Department of Veterans Affairs Health Care System.

JAMA Netw Open. 2020;3(10):e2014645. doi:10.1001/jamanetworkopen.2020.14645
Abstract Full Text pdf link PDF

MEDICAL JOURNALS AND PUBLISHING

Development and Validation of a Natural Language Processing Tool to Generate the CONSORT Reporting Checklist for Randomized Clinical Trials

This study evaluates an automated reporting checklist generation tool that uses natural language processing to improve adherence to the Consolidated Standards of Reporting Trials (CONSORT) reporting checklist for randomized clinical trials (RCTs).

JAMA Netw Open. 2020;3(10):e2014661. doi:10.1001/jamanetworkopen.2020.14661
Abstract Full Text pdf link PDF

UROLOGY

Association of State-Level Medicaid Expansion With Treatment of Patients With Higher-Risk Prostate Cancer

This cohort study evaluates whether patients with higher-risk prostate cancer residing in Medicaid expansion states were more likely to receive treatment after expansion compared with patients in states that did not pursue Medicaid expansion.

JAMA Netw Open. 2020;3(10):e2015198. doi:10.1001/jamanetworkopen.2020.15198
Abstract Full Text pdf link PDF

PEDIATRICS

Trends in the Incidence of Central Precocious Puberty and Normal Variant Puberty Among Children in Denmark, 1998 to 2017

This cohort study provides epidemiological data on the 20-year secular trend in the incidence rates of central precocious puberty and normal variant puberty among children in Denmark.

JAMA Netw Open. 2020;3(10):e2015665. doi:10.1001/jamanetworkopen.2020.15665
Abstract Full Text pdf link PDF

ONCOLOGY

Comparison of First-Line Treatments for Patients With Extensive-Stage Small Cell Lung Cancer: A Systematic Review and Network Meta-analysis

This systematic review and network meta-analysis clarifies which first-line treatment is associated with the best tumor response among patients with extensive-stage small cell lung cancer (SCLC).

JAMA Netw Open. 2020;3(10):e2015748. doi:10.1001/jamanetworkopen.2020.15748
Abstract Full Text pdf link PDF

ONCOLOGY

Association of Peer Comparison Emails With Electronic Health Record Documentation of Cancer Stage by Oncologists

This quality improvement pilot study evaluates whether an email intervention that communicates an oncologist’s performance in documenting cancer stage relative to that of peer physicians is associated with increased likelihood that stage is documented in the electronic health record (EHR).

JAMA Netw Open. 2020;3(10):e2015935. doi:10.1001/jamanetworkopen.2020.15935
Abstract Full Text pdf link PDF

SURGERY

Comparison of Safety and Insurance Payments for Minor Hand Procedures Across Operative Settings

This cohort study examines the differences in cost among hospital outpatient departments, ambulatory surgery centers, and office settings for minor hand surgical procedures.

JAMA Netw Open. 2020;3(10):e2015951. doi:10.1001/jamanetworkopen.2020.15951
Abstract Full Text pdf link PDF

ONCOLOGY

Cost-effectiveness of Pembrolizumab Plus Axitinib Vs Nivolumab Plus Ipilimumab as First-Line Treatment of Advanced Renal Cell Carcinoma in the US

This economic evaluation compares the cost-effectiveness of pembrolizumab-axitinib vs nivolumab-ipilimumab for treatment of advanced renal cell carcinoma (ARCC) in the US.

JAMA Netw Open. 2020;3(10):e2016144. doi:10.1001/jamanetworkopen.2020.16144
Abstract Full Text pdf link PDF

SUBSTANCE USE AND ADDICTION

Association of Treatment With Medications for Opioid Use Disorder With Mortality After Hospitalization for Injection Drug Use–Associated Infective Endocarditis

This cohort study assess the association of receipt of medication for opioid use disorder and mortality after hospitalization for injection drug use–associated infective endocarditis in Massachusetts.

JAMA Netw Open. 2020;3(10):e2016228. doi:10.1001/jamanetworkopen.2020.16228
Abstract Full Text pdf link PDF

HEALTH INFORMATICS

Comparison of Community-Level and Patient-Level Social Risk Data in a Network of Community Health Centers

This cross-sectional study explores the utility of community-level data for accurately identifying patients with social risks by comparing the social deprivation index score for the census tract where a patient lives with patient-level social risk screening data.

JAMA Netw Open. 2020;3(10):e2016852. doi:10.1001/jamanetworkopen.2020.16852
Abstract Full Text pdf link PDF

SURGERY

Association of Prehospital Plasma With Survival in Patients With Traumatic Brain Injury: A Secondary Analysis of the PAMPer Cluster Randomized Clinical Trial

This secondary analysis of a cluster randomized clinical trial assesses the association between prehospital plasma administration and survival in patients with traumatic brain injury.

has audio
JAMA Netw Open. 2020;3(10):e2016869. doi:10.1001/jamanetworkopen.2020.16869
Abstract Full Text pdf link PDF

HEALTH INFORMATICS

Assessment of Value of Neighborhood Socioeconomic Status in Models That Use Electronic Health Record Data to Predict Health Care Use Rates and Mortality

This diagnostic study assesses the value of including neighborhood socioeconomic status in models that use electronic health record (EHR) data to predict health care use rates and mortality among adults in a large integrated care system.

JAMA Netw Open. 2020;3(10):e2017109. doi:10.1001/jamanetworkopen.2020.17109
Abstract Full Text pdf link PDF

PSYCHIATRY

Virtual Standardized Patients vs Academic Training for Learning Motivational Interviewing Skills in the US Department of Veterans Affairs and the US Military: A Randomized Trial

This randomized trial of health care professionals evaluates the efficacy of training with a virtual standardized patient on the acquisition and maintenance of motivational interviewing skills compared with traditional academic study.

has audio
JAMA Netw Open. 2020;3(10):e2017348. doi:10.1001/jamanetworkopen.2020.17348
Abstract Full Text pdf link PDF

ENVIRONMENTAL HEALTH

Association of the Built Environment With Childhood Psychosocial Stress

This cohort study examines stress levels in children based on environment factors, including artificial light at night, near-roadway air pollution, noise, green space, and secondhand smoke.

JAMA Netw Open. 2020;3(10):e2017634. doi:10.1001/jamanetworkopen.2020.17634
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

Comparison of Antifungal Prophylaxis Drugs in Patients With Hematological Disease or Undergoing Hematopoietic Stem Cell Transplantation: A Systematic Review and Network Meta-analysis

This systematic review and network meta-analsysis compares antifungal prophylaxis drugs for patients with hematological disease or who are undergoing hematopoietic stem cell transplantation (HSCT).

JAMA Netw Open. 2020;3(10):e2017652. doi:10.1001/jamanetworkopen.2020.17652
Abstract Full Text pdf link PDF

HEALTH POLICY

Association of Infectious Disease Physician Approval of Peripherally Inserted Central Catheter With Appropriateness and Complications

This cohort study evaluates whether infectious disease physician approval prior to placement of a peripherally inserted central catheter (PICC) for intravenous antimicrobials is associated with more appropriate device use and fewer complications.

JAMA Netw Open. 2020;3(10):e2017659. doi:10.1001/jamanetworkopen.2020.17659
Abstract Full Text pdf link PDF

NEUROLOGY

Association of Uncommon, Noncoding Variants in the APOE Region With Risk of Alzheimer Disease in Adults of European Ancestry

This genetic association study assesses whether variants near the apolipoprotein E gene (APOE) are associated with Alzheimer disease independently of ε2/ε3/ε4 genotype.

JAMA Netw Open. 2020;3(10):e2017666. doi:10.1001/jamanetworkopen.2020.17666
Abstract Full Text pdf link PDF

ONCOLOGY

Survival-Inferred Fragility Index of Phase 3 Clinical Trials Evaluating Immune Checkpoint Inhibitors

This cross-sectional study calculates the fragility of survival data in randomized clinical trials evaluating immune checkpoint inhibitors.

JAMA Netw Open. 2020;3(10):e2017675. doi:10.1001/jamanetworkopen.2020.17675
Abstract Full Text pdf link PDF

NEPHROLOGY

Incidence of Hyponatremia in Patients With Indwelling Peritoneal Catheters for Drainage of Malignant Ascites

This cohort study evaluates the incidence of hyponatremia after the placement of indwelling peritoneal catheters for drainage of malignant ascites and the risk factors associated with its development.

JAMA Netw Open. 2020;3(10):e2017859. doi:10.1001/jamanetworkopen.2020.17859
Abstract Full Text pdf link PDF

CARDIOLOGY

Association of Viral Persistence and Atherosclerosis in Adults With Treated HIV Infection

This cohort study assesses whether higher levels of viral persistence are associated with atherosclerosis as assessed by changes in carotid artery intima-media thickness over time in patients living with HIV.

JAMA Netw Open. 2020;3(10):e2018099. doi:10.1001/jamanetworkopen.2020.18099
Abstract Full Text pdf link PDF

HEALTH POLICY

Perspectives of VA Primary Care Clinicians Toward Electronic Consultation-Related Workload Burden: A Qualitative Analysis

This qualitative study examines perceptions of the workload burden associated with electronic consultations among a national sample of Veterans Health Administration (VHA) primary care clinicians.

JAMA Netw Open. 2020;3(10):e2018104. doi:10.1001/jamanetworkopen.2020.18104
Abstract Full Text pdf link PDF

PEDIATRICS

Effect of Avoiding Cow's Milk Formula at Birth on Prevention of Asthma or Recurrent Wheeze Among Young Children: Extended Follow-up From the ABC Randomized Clinical Trial

This follow-up of the ABC randomized clinical trial compares the risk of asthma or recurrent wheeze among young children who were randomized as infants to either breastfeeding with cow’s milk formula supplementation or breastfeeding with or without elemental formula supplementation in the first few days of life.

JAMA Netw Open. 2020;3(10):e2018534. doi:10.1001/jamanetworkopen.2020.18534
Abstract Full Text pdf link PDF

GASTROENTEROLOGY AND HEPATOLOGY

Observational and Genetic Associations of Body Mass Index and Hepatobiliary Diseases in a Relatively Lean Chinese Population

This cohort study compares observational associations with genetic associations of body mass index with hepatobiliary diseases and liver biomarkers.

JAMA Netw Open. 2020;3(10):e2018721. doi:10.1001/jamanetworkopen.2020.18721
Abstract Full Text pdf link PDF

HEALTH POLICY

Association of Medicaid Expansion Under the Patient Protection and Affordable Care Act With Use of Long-term Care

This cohort study uses data from the Health and Retirement Study to examine the association between Patient Protection and Affordable Care Act funded–Medicaid expansion in 2014 and long-term care use among low-income, middle-aged adults newly eligible for Medicaid.

JAMA Netw Open. 2020;3(10):e2018728. doi:10.1001/jamanetworkopen.2020.18728
Abstract Full Text pdf link PDF

CARDIOLOGY

Association of Pretreatment With P2Y12 Receptor Antagonists Preceding Percutaneous Coronary Intervention in Non–ST-Segment Elevation Acute Coronary Syndromes With Outcomes

This cohort study examines the association of pretreatment with P2Y12 receptor antagonist with 30-day and 1-year mortality and in-hospital bleeding among patients with non–ST-segment elevation acute coronary syndromes (NSTE-ACS).

JAMA Netw Open. 2020;3(10):e2018735. doi:10.1001/jamanetworkopen.2020.18735
Abstract Full Text pdf link PDF

OBSTETRICS AND GYNECOLOGY

Evaluation of US State–Level Variation in Hypertensive Disorders of Pregnancy

This cross-sectional study examines statewide variations in the prevalence of hypertensive disorders in pregnant women across the US.

JAMA Netw Open. 2020;3(10):e2018741. doi:10.1001/jamanetworkopen.2020.18741
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ANESTHESIOLOGY

Association Between Preoperative Benzodiazepine Use and Postoperative Opioid Use and Health Care Costs

This cohort study analyzes the preoperative use of benzodiazepines compared with long-term postoperative use of opioids and association with health care costs.

JAMA Netw Open. 2020;3(10):e2018761. doi:10.1001/jamanetworkopen.2020.18761
Abstract Full Text pdf link PDF

MEDICAL EDUCATION

Association of Preferences for Participation in Decision-making With Care Satisfaction Among Hospitalized Patients

This survey study investigates the association of hospitalized patients’ desire to delegate decisions to their physician with care dissatisfaction.

JAMA Netw Open. 2020;3(10):e2018766. doi:10.1001/jamanetworkopen.2020.18766
Abstract Full Text pdf link PDF

PSYCHIATRY

Association of Cigarette Smoking With Cerebrospinal Fluid Biomarkers of Neurodegeneration, Neuroinflammation, and Oxidation

This case-control study investigates the association of cigarette smoking with cerebrospinal fluid biomarkers of neurodegeneration, neuroinflammation, oxidation, and neuroprotection.

JAMA Netw Open. 2020;3(10):e2018777. doi:10.1001/jamanetworkopen.2020.18777
Abstract Full Text pdf link PDF

ONCOLOGY

Regional Lymph Node Involvement Among Patients With De Novo Metastatic Breast Cancer

This cohort study examines whether and why regional node irradiation in patients with de novo metastatic breast cancer has different levels of effectiveness for preventing recurrences of cancer in regional nodes and distant mestastases.

JAMA Netw Open. 2020;3(10):e2018790. doi:10.1001/jamanetworkopen.2020.18790
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Trends in the Age of Cigarette Smoking Initiation Among Young Adults in the US From 2002 to 2018

This cross-sectional study assesses trends in early adult (ages 18-23 years) vs adolescent (age <18 years) cigarette smoking initiation and transition to daily cigarette smoking from 2002 to 2018.

JAMA Netw Open. 2020;3(10):e2019022. doi:10.1001/jamanetworkopen.2020.19022
Abstract Full Text pdf link PDF

PSYCHIATRY

Incidence of and Characteristics Associated With Long-term Benzodiazepine Use in Finland

This cohort study uses national longitudinal data from the Social Insurance Institution of Finland to investigate the incidence of long-term use of benzodiazepines and related drugs among new users and factors associated with development of long-term use.

JAMA Netw Open. 2020;3(10):e2019029. doi:10.1001/jamanetworkopen.2020.19029
Abstract Full Text pdf link PDF

PEDIATRICS

Associations of Cord Blood Vitamin D and Preeclampsia With Offspring Blood Pressure in Childhood and Adolescence

This cohort study assesses the associations between maternal preeclampsia and offspring systolic blood pressure across early childhood, middle childhood, and adolescence and investigates whether the association varies by cord blood plasma vitamin D level.

JAMA Netw Open. 2020;3(10):e2019046. doi:10.1001/jamanetworkopen.2020.19046
Abstract Full Text pdf link PDF

DIABETES AND ENDOCRINOLOGY

Prevalence of Hypothyroidism in Patients With Erdheim-Chester Disease

This cross-sectional study assesses rates of hypothalamus-pituitary-thyroid dysfunction in patients with Erdheim-Chester disease.

JAMA Netw Open. 2020;3(10):e2019169. doi:10.1001/jamanetworkopen.2020.19169
Abstract Full Text pdf link PDF

SUBSTANCE USE AND ADDICTION

Trajectories of Nicotine and Cannabis Vaping and Polyuse From Adolescence to Young Adulthood

This cohort study assesses the developmental trajectories of nicotine and cannabis vaping from late adolescence to young adulthood in Southern California.

JAMA Netw Open. 2020;3(10):e2019181. doi:10.1001/jamanetworkopen.2020.19181
Abstract Full Text pdf link PDF

ONCOLOGY

Association of Low Tumor Endothelial Cell pY397–Focal Adhesion Kinase Expression With Survival in Patients With Neoadjuvant-Treated Locally Advanced Breast Cancer

This prognostic study examines the use of endothelial cell phosphorylated-focal adhesion kinase as a biomarker for chemotherapy sensitivity in women with breast cancer.

JAMA Netw Open. 2020;3(10):e2019304. doi:10.1001/jamanetworkopen.2020.19304
Abstract Full Text pdf link PDF

SUBSTANCE USE AND ADDICTION

Changes in Cigarette Consumption With Reduced Nicotine Content Cigarettes Among Smokers With Psychiatric Conditions or Socioeconomic Disadvantage: 3 Randomized Clinical Trials

These 3 randomized clinical trials examine the efficacy of very low-nicotine-content cigarettes in reducing smoking rates among smokers with affective disorders, opioid use disorders, or socioeconomic disadvantage.

JAMA Netw Open. 2020;3(10):e2019311. doi:10.1001/jamanetworkopen.2020.19311
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Effect of Patient Financial Incentives on Statin Adherence and Lipid Control: A Randomized Clinical Trial

This randomized clinical trial examines whether 6-month interventions involving different financial incentives to encourage statin adherence reduce low-density lipoprotein cholesterol levels from baseline to 12 months.

JAMA Netw Open. 2020;3(10):e2019429. doi:10.1001/jamanetworkopen.2020.19429
Abstract Full Text pdf link PDF

ONCOLOGY

Icotinib With Concurrent Radiotherapy vs Radiotherapy Alone in Older Adults With Unresectable Esophageal Squamous Cell Carcinoma: A Phase II Randomized Clinical Trial

This randomized clinical trial assesses the efficacy and toxicity of radiotherapy plus icotinib compared with radiotherapy alone in older patients with unresectable esophageal squamous cell carcinoma (ESCC) in China.

JAMA Netw Open. 2020;3(10):e2019440. doi:10.1001/jamanetworkopen.2020.19440
Abstract Full Text pdf link PDF

ONCOLOGY

Yield and Utility of Germline Testing Following Tumor Sequencing in Patients With Cancer

This cohort study examines the prevalence of pathogenic germline variants in patients with cancer who had received DNA sequencing.

JAMA Netw Open. 2020;3(10):e2019452. doi:10.1001/jamanetworkopen.2020.19452
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Association Between Exposure to Hurricane Irma and Mortality and Hospitalization in Florida Nursing Home Residents

This cohort study assess the association between exposure to Hurricane Irma and 30- and 90-day mortality and morbidity among short- and long-term residents of nursing homes in Florida.

JAMA Netw Open. 2020;3(10):e2019460. doi:10.1001/jamanetworkopen.2020.19460
Abstract Full Text pdf link PDF

NUTRITION, OBESITY, AND EXERCISE

Association of Chain Restaurant Advertising Spending With Obesity in US Adults

This cohort study assesses whether changes in per capita county-level restaurant advertising spending from 2013 to 2016 are associated with changes in objectively measured body mass index in nearly 6 million US adults across 370 counties.

JAMA Netw Open. 2020;3(10):e2019519. doi:10.1001/jamanetworkopen.2020.19519
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Prevalence of Mental Illness and Mental Health Care Use Among Police Officers

This survey study assesses the prevalence of mental illness and mental health care use among police officers at a large, urban police department in the US.

JAMA Netw Open. 2020;3(10):e2019658. doi:10.1001/jamanetworkopen.2020.19658
Abstract Full Text pdf link PDF

SURGERY

Women Surgeons’ Experiences of Interprofessional Workplace Conflict

This qualitative study uses data from interviews via email and national surgical societies to investigate interprofessional workplace conflicts experienced by women surgeons.

JAMA Netw Open. 2020;3(10):e2019843. doi:10.1001/jamanetworkopen.2020.19843
Abstract Full Text pdf link PDF

HEALTH POLICY

Assessment of Behavioral Health Services Use Among Low-Income Medicare Beneficiaries After Reductions in Coinsurance Fees

This cohort study assesses the association of reductions in coinsurance for behavioral health services with behavioral health care use and spending among Medicare beneficiaries with severe mental illness.

JAMA Netw Open. 2020;3(10):e2019854. doi:10.1001/jamanetworkopen.2020.19854
Abstract Full Text pdf link PDF

SURGERY

Cost-effectiveness of Recurrent Dupuytren Contracture Treatment

This economic evaluation identifies the most cost-effective treatment regimen for patients with recurrent Dupuytren contracture.

JAMA Netw Open. 2020;3(10):e2019861. doi:10.1001/jamanetworkopen.2020.19861
Abstract Full Text pdf link PDF

HEALTH POLICY

Association of State Medicaid Expansion With Racial/Ethnic Disparities in Liver Transplant Wait-listing in the United States

This cohort study investigates the implications of state Medicaid expansion for liver transplant wait-listing trends for racial/ethnic minorities.

JAMA Netw Open. 2020;3(10):e2019869. doi:10.1001/jamanetworkopen.2020.19869
Abstract Full Text pdf link PDF

HEALTH POLICY

Ambulatory Follow-up and Outcomes Among Medicare Beneficiaries After Emergency Department Discharge

This cohort study examines the frequency and variation in ambulatory follow-up among Medicare beneficiaries discharged from US emergency departments (EDs) and the association between ambulatory follow-up and postdischarge outcomes.

JAMA Netw Open. 2020;3(10):e2019878. doi:10.1001/jamanetworkopen.2020.19878
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

Oral β-Lactam Antibiotics vs Fluoroquinolones or Trimethoprim-Sulfamethoxazole for Definitive Treatment of Enterobacterales Bacteremia From a Urine Source

This cohort study compares definitive therapy with oral β-lactam antibiotics vs fluoroquinolones or trimethoprim-sulfamethoxazole after 1 to 5 days of parenteral antibiotics for Enterobacterales bacteremia from a suspected urine source.

JAMA Netw Open. 2020;3(10):e2020166. doi:10.1001/jamanetworkopen.2020.20166
Abstract Full Text pdf link PDF

GASTROENTEROLOGY AND HEPATOLOGY

Thirty-Year Incidence and Mortality Trends in Upper and Lower Gastrointestinal Bleeding in Finland

This cohort study examines 30-year incidence and mortality trends in upper and lower gastrointestinal bleeding using nationwide health examination survey data from adults in different regions in Finland.

JAMA Netw Open. 2020;3(10):e2020172. doi:10.1001/jamanetworkopen.2020.20172
Abstract Full Text pdf link PDF

PUBLIC HEALTH

The Early Burden of Disability in Individuals With Mood and Other Common Mental Disorders in Ontario, Canada

This cohort study assesses the time between an incident mood or other common mental disorder diagnosis and the receipt of disability services during a follow-up period of as long as 20 years among adults in Ontario, Canada.

JAMA Netw Open. 2020;3(10):e2020213. doi:10.1001/jamanetworkopen.2020.20213
Abstract Full Text pdf link PDF

HEALTH POLICY

Use of Data-Driven Methods to Predict Long-term Patterns of Health Care Spending for Medicare Patients

This cohort study uses group-based trajectory modeling to assess the spending patterns of Medicare beneficiaries over a 2-year period and explores whether such a model can predict spending patterns using potentially modifiable patient characteristics.

JAMA Netw Open. 2020;3(10):e2020291. doi:10.1001/jamanetworkopen.2020.20291
Abstract Full Text pdf link PDF

OBSTETRICS AND GYNECOLOGY

Integration of Catholic Values and Professional Obligations in the Provision of Family Planning Services: A Qualitative Study

This qualitative study explores how Catholic obstetrician-gynecologists integrate their religious values and professional obligations related to family planning services.

JAMA Netw Open. 2020;3(10):e2020297. doi:10.1001/jamanetworkopen.2020.20297
Abstract Full Text pdf link PDF

ONCOLOGY

Variation in Breast Cancer Subtype Incidence and Distribution by Race/Ethnicity in the United States From 2010 to 2015

This cohort study describes the incidence rates of 4 breast cancer molecular subtypes stratified by race/ethnicity among women in the US.

JAMA Netw Open. 2020;3(10):e2020303. doi:10.1001/jamanetworkopen.2020.20303
Abstract Full Text pdf link PDF

ONCOLOGY

Association of Cyclin-Dependent Kinases 4 and 6 Inhibitors With Survival in Patients With Hormone Receptor–Positive Metastatic Breast Cancer: A Systematic Review and Meta-analysis

This systematic review and meta-analysis evaluates 9 randomized clinical trials to assess whether adding cyclin-dependent kinases 4 and 6 inhibitors to endocrine therapy is associated with increased overall survival or with adverse events vs endocrine therapy alone among patients with hormone receptor (HR)–positive, ERBB2-negative metastatic breast cancer.

JAMA Netw Open. 2020;3(10):e2020312. doi:10.1001/jamanetworkopen.2020.20312
Abstract Full Text pdf link PDF

PSYCHIATRY

Hypertension Treatment Modality and Suicide Risk Among Veterans in Veterans Health Administration Care From 2015 to 2017

This case-control study evaluated whether exposure to angiotensin receptor blockers is associated with differential suicide risk compared with exposure to angiotensin converting enzyme inhibitors among veterans in Veterans Health Administration care.

JAMA Netw Open. 2020;3(10):e2020330. doi:10.1001/jamanetworkopen.2020.20330
Abstract Full Text pdf link PDF

GERIATRICS

Family and Friend Perceptions of Quality of End-of-Life Care in Medicare Advantage vs Traditional Medicare

This cross-sectional study examines friend and family perceptions of quality of end-of-life care for individuals enrolled in Medicare Advantage at time of death vs those enrolled in traditional Medicare.

JAMA Netw Open. 2020;3(10):e2020345. doi:10.1001/jamanetworkopen.2020.20345
Abstract Full Text pdf link PDF

ONCOLOGY

Association of Bevacizumab Plus Oxaliplatin-Based Chemotherapy With Disease-Free Survival and Overall Survival in Patients With Stage II Colon Cancer: A Secondary Analysis of the AVANT Trial

This secondary analysis of the AVANT trial explores the efficacy of adjuvant bevacizumab combined with oxaliplatin-based chemotherapy and disease-free survival (DFS) rates in patients with high-risk, stage II colon cancer.

JAMA Netw Open. 2020;3(10):e2020425. doi:10.1001/jamanetworkopen.2020.20425
Abstract Full Text pdf link PDF

EMERGENCY MEDICINE

Estimating Nonfatal Gunshot Injury Locations With Natural Language Processing and Machine Learning Models

This cross-sectional study uses data from the National Electronic Injury Surveillance System Firearm Injury Surveillance Study to test the ability of natural language processing combined with 4 machine learning models to predict the locations of nonfatal gunshot injuries.

JAMA Netw Open. 2020;3(10):e2020664. doi:10.1001/jamanetworkopen.2020.20664
Abstract Full Text pdf link PDF

SUBSTANCE USE AND ADDICTION

Evaluation of Respiratory Symptoms Among Youth e-Cigarette Users

This cohort study uses data from the Population Assessment of Tobacco and Health from 2015 to 2018 to examine the association between wheezing and past-year use of e-cigarettes among youths.

JAMA Netw Open. 2020;3(10):e2020671. doi:10.1001/jamanetworkopen.2020.20671
Abstract Full Text pdf link PDF

NEUROLOGY

Human Prion Disease Surveillance in Washington State, 2006-2017

This cross-sectional study describes the current prion disease surveillance system in Washington state and reports the epidemiological and clinical results of surveillance activities from 2006 through 2017.

JAMA Netw Open. 2020;3(10):e2020690. doi:10.1001/jamanetworkopen.2020.20690
Abstract Full Text pdf link PDF

SUBSTANCE USE AND ADDICTION

Association of Violence Against Female Sex Workers Who Use Drugs With Nonfatal Drug Overdose in Kazakhstan

This cross-sectional study examines the association between intimate partner violence, nonpartner violence, and nonfatal drug overdose among female sex workers who use drugs in Kazakhstan.

JAMA Netw Open. 2020;3(10):e2020802. doi:10.1001/jamanetworkopen.2020.20802
Abstract Full Text pdf link PDF

PSYCHIATRY

Feasibility and Efficacy of a Resiliency Intervention for the Prevention of Chronic Emotional Distress Among Survivor-Caregiver Dyads Admitted to the Neuroscience Intensive Care Unit: A Randomized Clinical Trial

This pilot randomized clinical trial evaluates the feasibility and preliminary effect of the novel dyadic resiliency intervention Recovering Together in reducing symptoms of depression, anxiety, and posttraumatic stress among patients hospitalized in the neuroscience intensive care unit and their informal caregivers.

JAMA Netw Open. 2020;3(10):e2020807. doi:10.1001/jamanetworkopen.2020.20807
Abstract Full Text pdf link PDF

GERIATRICS

Bimagrumab vs Optimized Standard of Care for Treatment of Sarcopenia in Community-Dwelling Older Adults: A Randomized Clinical Trial

This randomized clinical trial examines diet and exercise plus bimagrumab vs placebo for physical function in a global population of older adults with sarcopenia.

JAMA Netw Open. 2020;3(10):e2020836. doi:10.1001/jamanetworkopen.2020.20836
Abstract Full Text pdf link PDF

HEALTH POLICY

Association of Veterans Affairs Primary Care Mental Health Integration With Care Access Among Men and Women Veterans

This cohort study of Veterans Health Administration (VA) health care records examines gender differences in care usage since the national integration of mental health services into primary care for veterans.

JAMA Netw Open. 2020;3(10):e2020955. doi:10.1001/jamanetworkopen.2020.20955
Abstract Full Text pdf link PDF

IMAGING

Temporal Trends in Cervical Spine Curvature of South Korean Adults Assessed by Deep Learning System Segmentation, 2006-2018

This cross-sectional study uses a deep learning system to analyze the temporal trends in cervical spine curvature across sex and age groups in a population of South Korean adults.

JAMA Netw Open. 2020;3(10):e2020961. doi:10.1001/jamanetworkopen.2020.20961
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Self-reported Cannabidiol (CBD) Use for Conditions With Proven Therapies

This case series assesses whether individuals are using cannabidiol (CBD) to treat diagnosable conditions with proven therapies.

JAMA Netw Open. 2020;3(10):e2020977. doi:10.1001/jamanetworkopen.2020.20977
Abstract Full Text pdf link PDF

CARDIOLOGY

Geographic Variation in Process and Outcomes of Care for Patients With Acute Myocardial Infarction in China From 2001 to 2015

This cross-sectional study evaluates geographic variation and its change with time in treatment process and outcomes for patients with acute myocardial infarction in China.

JAMA Netw Open. 2020;3(10):e2021182. doi:10.1001/jamanetworkopen.2020.21182
Abstract Full Text pdf link PDF

ORTHOPEDICS

Association of Laminar Airflow During Primary Total Joint Arthroplasty With Periprosthetic Joint Infection

This cohort study examines the association between operating room laminar airflow ventilation systems and the risk of periprosthetic joint infection in patients undergoing total joint arthroplasty.

JAMA Netw Open. 2020;3(10):e2021194. doi:10.1001/jamanetworkopen.2020.21194
Abstract Full Text pdf link PDF

HEALTH POLICY

Assessment of Social Risk Factors and Interest in Receiving Health Care–Based Social Assistance Among Adult Patients and Adult Caregivers of Pediatric Patients

This cross-sectional study assesses social risk factors and examines characteristics associated with interest in receiving health care–based social risk assistance among adult patients and adult caregivers of pediatric patients.

JAMA Netw Open. 2020;3(10):e2021201. doi:10.1001/jamanetworkopen.2020.21201
Abstract Full Text pdf link PDF

STATISTICS AND RESEARCH METHODS

Patient-Reported Social and Behavioral Determinants of Health and Estimated Risk of Hospitalization in High-Risk Veterans Affairs Patients

This survey study describes social and behavioral determinants of health self-reported by Veterans Affairs patients who are at high risk for hospitalization and assesses whether adding these measures to a model based on electronic health record data improves the accuracy of estimates of 90-day and 180-day all-cause hospital admission risk.

JAMA Netw Open. 2020;3(10):e2021457. doi:10.1001/jamanetworkopen.2020.21457
Abstract Full Text pdf link PDF

HEALTH POLICY

Use and Content of Primary Care Office-Based vs Telemedicine Care Visits During the COVID-19 Pandemic in the US

This cross-sectional study uses data from the National Disease and Therapeutic Index to quantify changes in volume and type of primary care visits and changes in visit content associated with the COVID-19 pandemic in the US.

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JAMA Netw Open. 2020;3(10):e2021476. doi:10.1001/jamanetworkopen.2020.21476
Abstract Full Text pdf link PDF CME & MOC

CARDIOLOGY

Association of Hospital-Level Differences in Care With Outcomes Among Patients With Acute ST-Segment Elevation Myocardial Infarction in China

This cross-sectional study examines the variations in care and outcomes of patients with acute ST-segment elevation myocardial infarction (STEMI) at 3 different levels of hospitals—province, prefecture, and county—in China.

JAMA Netw Open. 2020;3(10):e2021677. doi:10.1001/jamanetworkopen.2020.21677
Abstract Full Text pdf link PDF

GLOBAL HEALTH

Access to Care and Prevalence of Hypertension and Diabetes Among Syrian Refugees in Northern Jordan

This cross-sectional study estimates the prevalence of hypertension and diabetes with biological measures and evaluates access to care among Syrian refugees in northern Jordan.

JAMA Netw Open. 2020;3(10):e2021678. doi:10.1001/jamanetworkopen.2020.21678
Abstract Full Text pdf link PDF

HEALTH POLICY

A Comparison of Online Medical Crowdfunding in Canada, the UK, and the US

This cross-sectional study examines medical crowdfunding campaigns in Canada, the UK, and the US and evaluates whether campaign types and demographic characteristics of the beneficiaries are associated with the amounts of money raised.

JAMA Netw Open. 2020;3(10):e2021684. doi:10.1001/jamanetworkopen.2020.21684
Abstract Full Text pdf link PDF

ONCOLOGY

Activity of Platinum-Based Chemotherapy in Patients With Advanced Prostate Cancer With and Without DNA Repair Gene Aberrations

This case series characterizes the antitumor activity of platinum-based therapies in men with castration-resistant prostate cancer with or without DNA repair gene alterations.

JAMA Netw Open. 2020;3(10):e2021692. doi:10.1001/jamanetworkopen.2020.21692
Abstract Full Text pdf link PDF

HEALTH POLICY

Association of Maternal Citizenship and State-Level Immigrant Policies With Health Insurance Coverage Among US-Born Latino Youths

This cross-sectional study uses data from the American Community Survey to examine the association of state-level immigrant integration and criminalization policies and maternal citizenship status with health insurance coverage among US-born Latino youths.

JAMA Netw Open. 2020;3(10):e2021876. doi:10.1001/jamanetworkopen.2020.21876
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

Association of Infection With Human Papillomavirus and Development of End-Stage Kidney Disease in Taiwan

This cohort study investigates the association of human papillomavirus infection status with development of end-stage kidney disease in Taiwan.

JAMA Netw Open. 2020;3(10):e2022107. doi:10.1001/jamanetworkopen.2020.22107
Abstract Full Text pdf link PDF

HEALTH POLICY

Assessment of Rural-Urban Differences in Health Care Use and Survival Among Medicare Beneficiaries With Alzheimer Disease and Related Dementia

This cohort study uses Medicare claims data from nursing home and home health assessments from all US counties to investigate how health care use and survival compares between individuals with Alzheimer disease and related dementia in rural vs urban settings.

JAMA Netw Open. 2020;3(10):e2022111. doi:10.1001/jamanetworkopen.2020.22111
Abstract Full Text pdf link PDF

CARDIOLOGY

Concordance of Cardiovascular Risk Factors and Behaviors in a Multiethnic US Nationwide Cohort of Married Couples and Domestic Partners

This cross-sectional study assesses the within-couple concordance of cardiovascular risk factors and behaviors within couples who participated in a nationwide US employer-sponsored health assessment program.

JAMA Netw Open. 2020;3(10):e2022119. doi:10.1001/jamanetworkopen.2020.22119
Abstract Full Text pdf link PDF

ONCOLOGY

Incidence and Mortality of Second Primary Cancers in Danish Patients With Retinoblastoma, 1943-2013

This cohort study examines the incidence of and mortality associated with second primary cancers that develop after diagnosis of retinoblastoma in Danish patients.

JAMA Netw Open. 2020;3(10):e2022126. doi:10.1001/jamanetworkopen.2020.22126
Abstract Full Text pdf link PDF

CARDIOLOGY

Temporal Trends in Heart Failure Incidence Among Medicare Beneficiaries Across Risk Factor Strata, 2011 to 2016

This national cohort study evaluates trends in heart failure incidence across risk factor strata, including hypertension, diabetes, obesity, acute myocardial infarction, and atrial fibrillation among Medicare beneficiaries.

JAMA Netw Open. 2020;3(10):e2022190. doi:10.1001/jamanetworkopen.2020.22190
Abstract Full Text pdf link PDF

HEALTH POLICY

Prevalence and Characteristics of Telehealth Utilization in the United States

This survey study of participants in an online panel examined willingness to participate in telehealth services to access health services with remote clinicians among participants categorized by sex, age, race/ethnicity, income, and education level.

JAMA Netw Open. 2020;3(10):e2022302. doi:10.1001/jamanetworkopen.2020.22302
Abstract Full Text pdf link PDF

HEALTH POLICY

Association of Discharge to Home vs Institutional Postacute Care With Outcomes After Lower Extremity Joint Replacement

This cohort study evaluates the association of discharge home vs discharge to institutional postacute care with outcomes following elective lower extremity total joint replacement.

JAMA Netw Open. 2020;3(10):e2022382. doi:10.1001/jamanetworkopen.2020.22382
Abstract Full Text pdf link PDF

PEDIATRICS

Comparison of Acetaminophen (Paracetamol) With Ibuprofen for Treatment of Fever or Pain in Children Younger Than 2 Years: A Systematic Review and Meta-analysis

This systematic review and meta-analysis compares acetaminophen with ibuprofen for the short-term treatment of fever or pain in children younger than 2 years.

JAMA Netw Open. 2020;3(10):e2022398. doi:10.1001/jamanetworkopen.2020.22398
Abstract Full Text pdf link PDF

HEALTH POLICY

Assessment of Rates of Suicide Risk Screening and Prevalence of Positive Screening Results Among US Veterans After Implementation of the Veterans Affairs Suicide Risk Identification Strategy

This cross-sectional study examines the prevalence of positive suicide screening results among veterans in ambulatory care and emergency departments or urgent care clinics and compare acuity of suicide risk among patients screened in these settings.

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JAMA Netw Open. 2020;3(10):e2022531. doi:10.1001/jamanetworkopen.2020.22531
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Effect of the Wingman-Connect Upstream Suicide Prevention Program for Air Force Personnel in Training: A Cluster Randomized Clinical Trial

This cluster randomized clinical trial examines whether the Wingman-Connect program for US Air Force personnel reduces suicidal ideation, depression, and occupational problems compared with a stress management program.

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JAMA Netw Open. 2020;3(10):e2022532. doi:10.1001/jamanetworkopen.2020.22532
Abstract Full Text pdf link PDF

IMAGING

Comparison of Chest Radiograph Interpretations by Artificial Intelligence Algorithm vs Radiology Residents

This diagnostic study examines the area under the curve, sensitivity, specificity, and positive predictive value of chest radiograph readings performed by an artificial intelligence algorithm vs by radiology residents.

JAMA Netw Open. 2020;3(10):e2022779. doi:10.1001/jamanetworkopen.2020.22779
Abstract Full Text pdf link PDF

COMPLEMENTARY AND ALTERNATIVE MEDICINE

Effect of Electroacupuncture vs Sham Treatment on Change in Pain Severity Among Adults With Chronic Low Back Pain: A Randomized Clinical Trial

This randomized clinical trial examines real vs sham electropuncture in treating chronic low back pain in adults.

JAMA Netw Open. 2020;3(10):e2022787. doi:10.1001/jamanetworkopen.2020.22787
Abstract Full Text pdf link PDF

PSYCHIATRY

Mental Health Status of Cisgender and Gender-Diverse Secondary School Students in China

This cross-sectional study uses data from questionnaires completed by adolescents in secondary schools in Suzhou city, China, to investigate the mental health challenges of youth identifying as transgender and gender nonconforming compared with cisgender adolescents.

JAMA Netw Open. 2020;3(10):e2022796. doi:10.1001/jamanetworkopen.2020.22796
Abstract Full Text pdf link PDF

NEUROLOGY

Rates of Brain Atrophy Across Disease Stages in Familial Frontotemporal Dementia Associated With MAPT, GRN, and C9orf72 Pathogenic Variants

This observation study characterizes regions and rates of atrophy in the 3 primary familial frontotemporal lobar degeneration genes (MAPT, GRN, and C9orf72) across all disease stages from asymptomatic to dementia.

JAMA Netw Open. 2020;3(10):e2022847. doi:10.1001/jamanetworkopen.2020.22847
Abstract Full Text pdf link PDF

GENETICS AND GENOMICS

Cost-effectiveness of Population-Wide Genomic Screening for Hereditary Breast and Ovarian Cancer in the United States

This decision analysis estimates the lifetime incremental incidence of hereditary breast and ovarian cancer and the quality-adjusted life-years, costs, and cost-effectiveness of hereditary breast and ovarian cancer genomic screening in an unselected population vs family history–based testing.

JAMA Netw Open. 2020;3(10):e2022874. doi:10.1001/jamanetworkopen.2020.22874
Abstract Full Text pdf link PDF

CARDIOLOGY

Assessment of Outcomes Among Patients With Venous Thromboembolism With and Without Chronic Kidney Disease

This cohort study uses data from participants in the Global Anticoagulant Registry in the Field–Venous Thromboembolism study to examine outcomes among adult patients with venous thromboembolism with and without moderate to severe chronic kidney disease.

JAMA Netw Open. 2020;3(10):e2022886. doi:10.1001/jamanetworkopen.2020.22886
Abstract Full Text pdf link PDF

HEALTH POLICY

National Poison Center Calls Before vs After Availability of High-Dose Acetaminophen (Paracetamol) Tablets in Switzerland

This cross-sectional study evaluates the association of adding 1000-mg acetaminophen tablets to the Swiss market with utilization and poisonings.

JAMA Netw Open. 2020;3(10):e2022897. doi:10.1001/jamanetworkopen.2020.22897
Abstract Full Text pdf link PDF

HEALTH POLICY

Assessment of Changes in Rural and Urban Primary Care Workforce in the United States From 2009 to 2017

This cross-sectional study examines and compares the primary care workforce and its growth between urban and rural counties or county-equivalents from 2009 to 2017 in the US.

JAMA Netw Open. 2020;3(10):e2022914. doi:10.1001/jamanetworkopen.2020.22914
Abstract Full Text pdf link PDF

ONCOLOGY

Assessment of Birth Defects and Cancer Risk in Children Conceived via In Vitro Fertilization in the US

This population-based cohort study assesses the association between birth defects and cancer risk among children conceived via in vitro fertilization vs children conceived naturally in 4 US states.

JAMA Netw Open. 2020;3(10):e2022927. doi:10.1001/jamanetworkopen.2020.22927
Abstract Full Text pdf link PDF

CARDIOLOGY

Performance of the Pooled Cohort Equations to Estimate Atherosclerotic Cardiovascular Disease Risk by Body Mass Index

This cohort study evaluates the performance of the pooled cohort equations in estimating the risk of atherosclerotic cardiovascular disease risk by body mass index range.

JAMA Netw Open. 2020;3(10):e2023242. doi:10.1001/jamanetworkopen.2020.23242
Abstract Full Text pdf link PDF

GENETICS AND GENOMICS

Fine Mapping of the Major Histocompatibility Complex Region and Association of the HLA-B*52:01 Allele With Cervical Cancer in Japanese Women

This genetic association study uses fine mapping of the major histocompatibility complex (MHC) region by human leukocyte antigen imputation to determine whether the HLA-B*52:01 allele is associated with cervical cancer (CC) in Japanese women.

JAMA Netw Open. 2020;3(10):e2023248. doi:10.1001/jamanetworkopen.2020.23248
Abstract Full Text pdf link PDF

PATHOLOGY AND LABORATORY MEDICINE

Evaluation of Concordance Between Original Death Certifications and an Expert Panel Process in the Determination of Sudden Unexplained Death in Childhood

This case series evaluates the frequency of sudden unexplained death in childhood (SUDC), explains its epidemiology, and assesses the consistency of death certification among medical examiner and coroner offices in the US death investigation system.

JAMA Netw Open. 2020;3(10):e2023262. doi:10.1001/jamanetworkopen.2020.23262
Abstract Full Text pdf link PDF

ONCOLOGY

Association of Diet Quality With Survival Among People With Metastatic Colorectal Cancer in the Cancer and Leukemia B and Southwest Oncology Group 80405 Trial

This cohort study of patients with metastatic colorectal cancer examines associations between diet at initiation of first-line treatment and overall survival.

JAMA Netw Open. 2020;3(10):e2023500. doi:10.1001/jamanetworkopen.2020.23500
Abstract Full Text pdf link PDF

HEALTH INFORMATICS

Laboratory Findings Associated With Severe Illness and Mortality Among Hospitalized Individuals With Coronavirus Disease 2019 in Eastern Massachusetts

This cohort study assesses admission laboratory and comorbidity features associated with critical illness and mortality risk among patients hospitalized with coronavirus disease 2019 (COVID-19) across 6 Eastern Massachusetts hospitals.

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JAMA Netw Open. 2020;3(10):e2023934. doi:10.1001/jamanetworkopen.2020.23934
Abstract Full Text pdf link PDF CME & MOC

INFECTIOUS DISEASES

Analysis of Genomic Characteristics and Transmission Routes of Patients With Confirmed SARS-CoV-2 in Southern California During the Early Stage of the US COVID-19 Pandemic

This case series examines the genomic characteristics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections and transmission routes during the early stages of the coronavirus disease 2019 (COVID-19) outbreak in Los Angeles, California.

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JAMA Netw Open. 2020;3(10):e2024191. doi:10.1001/jamanetworkopen.2020.24191
Abstract Full Text pdf link PDF CME & MOC

ONCOLOGY

Prevalence of High Tumor Mutational Burden and Association With Survival in Patients With Less Common Solid Tumors

This cohort study examines tumor mutational burden in patients with uncommon cancers not receiving immunotherapy as a biomarker associated with overall survival.

JAMA Netw Open. 2020;3(10):e2025109. doi:10.1001/jamanetworkopen.2020.25109
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

Characteristics Associated With Racial/Ethnic Disparities in COVID-19 Outcomes in an Academic Health Care System

This cohort study examines sociodemographic characteristics associated with coronavirus disease 2019 outcomes among Black and White patients in Michigan.

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JAMA Netw Open. 2020;3(10):e2025197. doi:10.1001/jamanetworkopen.2020.25197
Abstract Full Text pdf link PDF CME & MOC

PSYCHIATRY

Factors Associated With Mental Health Disorders Among University Students in France Confined During the COVID-19 Pandemic

This survey study measures the prevalence of self-reported mental health symptoms, identifies associated factors, and assesses care seeking among university students in France who experienced quarantine during the coronavirus disease 2019 (COVID-19) pandemic.

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JAMA Netw Open. 2020;3(10):e2025591. doi:10.1001/jamanetworkopen.2020.25591
Abstract Full Text pdf link PDF CME & MOC

PUBLIC HEALTH

Factors Associated With US Adults’ Likelihood of Accepting COVID-19 Vaccination

This survey study evaluates the factors associated with US adults’ choice of and willingness to accept a hypothetical COVID-19 vaccine.

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JAMA Netw Open. 2020;3(10):e2025594. doi:10.1001/jamanetworkopen.2020.25594
Abstract Full Text pdf link PDF CME & MOC

PUBLIC HEALTH

Association of State Stay-at-Home Orders and State-Level African American Population With COVID-19 Case Rates

This cross-sectional study examines the associations of state-level stay-at-home orders and proportion of African American population with coronavirus disease 2019 (COVID-19) case rates from March to May 2020.

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JAMA Netw Open. 2020;3(10):e2026010. doi:10.1001/jamanetworkopen.2020.26010
Abstract Full Text pdf link PDF CME & MOC

PUBLIC HEALTH

Levels of Severity of Depressive Symptoms Among At-Risk Groups in the UK During the COVID-19 Pandemic

This cohort study examines the levels of severity of depressive symptoms among at-risk individuals during the COVID-19 pandemic in the UK.

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JAMA Netw Open. 2020;3(10):e2026064. doi:10.1001/jamanetworkopen.2020.26064
Abstract Full Text pdf link PDF CME & MOC

PUBLIC HEALTH

Estimated Association of Construction Work With Risks of COVID-19 Infection and Hospitalization in Texas

This decision analytical model assesses the association between construction work during the coronavirus disease 2019 (COVID-19) pandemic and hospitalization rates for construction workers and the surrounding community.

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JAMA Netw Open. 2020;3(10):e2026373. doi:10.1001/jamanetworkopen.2020.26373
Abstract Full Text pdf link PDF CME & MOC

HEALTH POLICY

Comparative Performance of Private Equity–Owned US Nursing Homes During the COVID-19 Pandemic

This cross-sectional study evaluates the comparative performance of private equity–owned nursing homes on coronavirus disease 2019 (COVID-19) outcomes.

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JAMA Netw Open. 2020;3(10):e2026702. doi:10.1001/jamanetworkopen.2020.26702
Abstract Full Text pdf link PDF CME & MOC
open access Consensus Statement

CRITICAL CARE MEDICINE

Recommendations on Acute Kidney Injury Biomarkers From the Acute Disease Quality Initiative Consensus Conference: A Consensus Statement

This consensus statement develops recommendations on acute kidney injury biomarkers based on existing data and expert consensus for practicing clinicians and researchers.

JAMA Netw Open. 2020;3(10):e2019209. doi:10.1001/jamanetworkopen.2020.19209
Abstract Full Text pdf link PDF
open access Editorial

Hard Truths About Suicide Prevention

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JAMA Netw Open. 2020;3(10):e2022713. doi:10.1001/jamanetworkopen.2020.22713
Abstract Full Text pdf link PDF
open access Invited Commentary

SURGERY

Determining the Optimal Location for Minor Procedures—Goldilocks Medicine and the Just-Right Surgical Setting

JAMA Netw Open. 2020;3(10):e2016127. doi:10.1001/jamanetworkopen.2020.16127
Abstract Full Text pdf link PDF

SURGERY

Prehospital Plasma Resuscitation in Patients With Traumatic Brain Injury: PAMPering the Brain

JAMA Netw Open. 2020;3(10):e2017590. doi:10.1001/jamanetworkopen.2020.17590
Abstract Full Text pdf link PDF

OBSTETRICS AND GYNECOLOGY

Hypertension in Pregnancy in the US—One Step Closer to Better Ascertainment and Management

JAMA Netw Open. 2020;3(10):e2019364. doi:10.1001/jamanetworkopen.2020.19364
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Young Adults as a Tobacco Control Priority Population in the US

JAMA Netw Open. 2020;3(10):e2019365. doi:10.1001/jamanetworkopen.2020.19365
Abstract Full Text pdf link PDF

SUBSTANCE USE AND ADDICTION

Is Nicotine Reduction in Cigarettes Enough?

JAMA Netw Open. 2020;3(10):e2019367. doi:10.1001/jamanetworkopen.2020.19367
Abstract Full Text pdf link PDF

NUTRITION, OBESITY, AND EXERCISE

Restaurant Advertising and Population Health

JAMA Netw Open. 2020;3(10):e2019889. doi:10.1001/jamanetworkopen.2020.19889
Abstract Full Text pdf link PDF

PUBLIC HEALTH

On Policing—A Matter of Psychological Survival

JAMA Netw Open. 2020;3(10):e2020231. doi:10.1001/jamanetworkopen.2020.20231
Abstract Full Text pdf link PDF

HEALTH POLICY

Going Beyond Cost-Sharing Parity to Improve Behavioral Health Access

JAMA Netw Open. 2020;3(10):e2020232. doi:10.1001/jamanetworkopen.2020.20232
Abstract Full Text pdf link PDF

PUBLIC HEALTH

The Importance of Considering Clinical Inertia and Implementation Science When Addressing Medication Adherence

JAMA Netw Open. 2020;3(10):e2020233. doi:10.1001/jamanetworkopen.2020.20233
Abstract Full Text pdf link PDF

PSYCHIATRY

Mitigating Postintensive Care Syndrome Among Patients And Caregivers via a Dyadic Intervention

JAMA Netw Open. 2020;3(10):e2021014. doi:10.1001/jamanetworkopen.2020.21014
Abstract Full Text pdf link PDF

ONCOLOGY

In Support of CDK4/6 Inhibitors—A Meta-analysis of Available Randomized Data

JAMA Netw Open. 2020;3(10):e2021062. doi:10.1001/jamanetworkopen.2020.21062
Abstract Full Text pdf link PDF

GERIATRICS

Quality of End-of-Life Care for Medicare Advantage Enrollees—Does It Measure Up?

JAMA Netw Open. 2020;3(10):e2021063. doi:10.1001/jamanetworkopen.2020.21063
Abstract Full Text pdf link PDF

ONCOLOGY

Antiangiogenesis in Early-Stage Colon Cancer—Microscopically Busted

JAMA Netw Open. 2020;3(10):e2021064. doi:10.1001/jamanetworkopen.2020.21064
Abstract Full Text pdf link PDF

SUBSTANCE USE AND ADDICTION

Addressing Violence and Overdose Among Women Who Use Drugs—Need for Structural Interventions

JAMA Netw Open. 2020;3(10):e2021066. doi:10.1001/jamanetworkopen.2020.21066
Abstract Full Text pdf link PDF

PUBLIC HEALTH

The Need for Evidence Regarding Cannabidiol

JAMA Netw Open. 2020;3(10):e2021067. doi:10.1001/jamanetworkopen.2020.21067
Abstract Full Text pdf link PDF

ORTHOPEDICS

One More Study Showing No Benefit Associated With Laminar Flow in the Operating Room

JAMA Netw Open. 2020;3(10):e2021488. doi:10.1001/jamanetworkopen.2020.21488
Abstract Full Text pdf link PDF

ONCOLOGY

Homologous Recombination DNA Repair Gene Aberrations—Are We More Alike Than Different?

JAMA Netw Open. 2020;3(10):e2021717. doi:10.1001/jamanetworkopen.2020.21717
Abstract Full Text pdf link PDF

HEALTH POLICY

The Pandemic of Health Care Inequity

JAMA Netw Open. 2020;3(10):e2021767. doi:10.1001/jamanetworkopen.2020.21767
Abstract Full Text pdf link PDF

CARDIOLOGY

Lessons Learned From Acute Myocardial Infarction Care in China

JAMA Netw Open. 2020;3(10):e2021768. doi:10.1001/jamanetworkopen.2020.21768
Abstract Full Text pdf link PDF

STATISTICS AND RESEARCH METHODS

Applying a Population Health Equity Framework in the Clinical Setting—Incorporating Social and Behavioral Determinants of Health Into Estimations of Risk

JAMA Netw Open. 2020;3(10):e2021771. doi:10.1001/jamanetworkopen.2020.21771
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

USS Theodore Roosevelt, COVID-19, and Ships: Lessons Learned

JAMA Netw Open. 2020;3(10):e2022095. doi:10.1001/jamanetworkopen.2020.22095
Abstract Full Text pdf link PDF

ONCOLOGY

Heritable Retinoblastoma and Risk of Developing Second Primary Cancer

JAMA Netw Open. 2020;3(10):e2022569. doi:10.1001/jamanetworkopen.2020.22569
Abstract Full Text pdf link PDF

PSYCHIATRY

Mental Health of Transgender Adolescents Around the Globe—A Call for Comprehensive Assessment of Gender Identity

JAMA Netw Open. 2020;3(10):e2023412. doi:10.1001/jamanetworkopen.2020.23412
Abstract Full Text pdf link PDF

ONCOLOGY

Diet Quality at the Initiation of Treatment for Metastatic Colorectal Cancer

JAMA Netw Open. 2020;3(10):e2023718. doi:10.1001/jamanetworkopen.2020.23718
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Building Trust to Achieve Confidence in COVID-19 Vaccines

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JAMA Netw Open. 2020;3(10):e2025672. doi:10.1001/jamanetworkopen.2020.25672
Abstract Full Text pdf link PDF CME & MOC
open access Research Letter

HEALTH INFORMATICS

Assessment of Year-to-Year Patient-Specific Comorbid Conditions Reported in the Medicare Chronic Conditions Data Warehouse

This cross-sectional study evaluates the persistence of chronic condition flags for 51 conditions over single-year and multiyear periods.

JAMA Netw Open. 2020;3(10):e2018176. doi:10.1001/jamanetworkopen.2020.18176
Abstract Full Text pdf link PDF

HEALTH POLICY

Evaluation of Work Satisfaction, Stress, and Burnout Among US Internal Medicine Physicians and Trainees

This study uses the Mini Z 2.0 survey to assess burnout among male and female members of the American College of Physicians who are internists and internal medicine trainees.

JAMA Netw Open. 2020;3(10):e2018758. doi:10.1001/jamanetworkopen.2020.18758
Abstract Full Text pdf link PDF

HEALTH POLICY

Association of Use of an Integrated Specialty Pharmacy With Total Medical Expenditures Among Members of an Accountable Care Organization

This cohort study examines the association of integrated specialty pharmacy use among members of a university hospital accountable care organization (ACO) with total medical expenditure.

JAMA Netw Open. 2020;3(10):e2018772. doi:10.1001/jamanetworkopen.2020.18772
Abstract Full Text pdf link PDF

OBSTETRICS AND GYNECOLOGY

Association of Past Chlamydia trachomatis Infection With Miscarriage

This case-control study assesses the association between past Chlamydia trachomatis infection with first-trimester miscarriage by using an enzyme-linked immunosorbent assay to detect antibodies to the protein Pgp3.

JAMA Netw Open. 2020;3(10):e2018799. doi:10.1001/jamanetworkopen.2020.18799
Abstract Full Text pdf link PDF

OBSTETRICS AND GYNECOLOGY

Disparities in Adverse Maternal Outcomes Among Asian Women in the US Delivering at Term

This population-based retrospective cohort study used US Vital Statistics data from 2014-2017 to assess the risk of adverse maternal outcomes at term for Asian women in the US.

JAMA Netw Open. 2020;3(10):e2020180. doi:10.1001/jamanetworkopen.2020.20180
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Demographic Characteristics, Cigarette Smoking, and e-Cigarette Use Among US Adults

This cross-sectional study examines the demographic characteristics of adult cigarette smokers and e-cigarette users in the US.

JAMA Netw Open. 2020;3(10):e2020694. doi:10.1001/jamanetworkopen.2020.20694
Abstract Full Text pdf link PDF

DIABETES AND ENDOCRINOLOGY

Coverage, Formulary Restrictions, and Out-of-Pocket Costs for Sodium-Glucose Cotransporter 2 Inhibitors and Glucagon-Like Peptide 1 Receptor Agonists in the Medicare Part D Program

This cross-sectional study assesses drug coverage, formulary restrictions, median retail prices, and annual out-of-pocket costs associated with commonly used insulin products across Medicare Part D plans.

JAMA Netw Open. 2020;3(10):e2020969. doi:10.1001/jamanetworkopen.2020.20969
Abstract Full Text pdf link PDF

PSYCHIATRY

Magnetic Resonance Spectroscopy of γ-Aminobutyric Acid and Glutamate Concentrations in Children With Attention-Deficit/Hyperactivity Disorder

This cohort study assesses concentrations of γ-aminobutyric acid (GABA) and glutamate in children with attention-deficit/hyperactivity disorder (ADHD) compared with typically developing children.

JAMA Netw Open. 2020;3(10):e2020973. doi:10.1001/jamanetworkopen.2020.20973
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

Symptom Characterization and Outcomes of Sailors in Isolation After a COVID-19 Outbreak on a US Aircraft Carrier

This case series describes the symptoms and outcomes of sailors during and after an outbreak of coronavirus disease 2019 (COVID-19) on the USS Theodore Roosevelt.

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JAMA Netw Open. 2020;3(10):e2020981. doi:10.1001/jamanetworkopen.2020.20981
Abstract Full Text pdf link PDF CME & MOC

PSYCHIATRY

Estimates of Workload Associated With Suicide Risk Alerts After Implementation of Risk-Prediction Model

This cohort study attempts to validate the Mental Health Research Network suicide risk–prediction model and estimate associated workloads.

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JAMA Netw Open. 2020;3(10):e2021189. doi:10.1001/jamanetworkopen.2020.21189
Abstract Full Text pdf link PDF

ONCOLOGY

Clinician and Patient Characteristics Associated With Lung Cancer Screening Following a Shared Decision-making Visit

This cohort study explores whether clinician specialty and patient familiarity with the attending clinician are associated with rates of low-dose computerized tomographic lung cancer screening after shared decision-making visits.

JAMA Netw Open. 2020;3(10):e2021197. doi:10.1001/jamanetworkopen.2020.21197
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EMERGENCY MEDICINE

Trends in the Use of Buprenorphine in US Emergency Departments, 2002-2017

This cross-sectional study examines the trends in initiation of buprenorphine treatment for opioid use disorder during emergency department visits in the United States.

JAMA Netw Open. 2020;3(10):e2021209. doi:10.1001/jamanetworkopen.2020.21209
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PUBLIC HEALTH

Association of Rurality With Availability of Youth Mental Health Facilities With Suicide Prevention Services in the US

This cross-sectional study uses 2017 to 2019 data from the US National Mental Health Services Survey and examines whether there are disparities in the availability of youth-serving mental health facilities associated with suicide risk in rural vs urban youth.

JAMA Netw Open. 2020;3(10):e2021471. doi:10.1001/jamanetworkopen.2020.21471
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HEALTH POLICY

Investments in Community Building Among Nonprofit Hospital Organizations in the United States

This cross-sectional analysis of a national sample of nonprofit, acute care hospital organizations assesses how these organizations distribute spending for community-building activities among the 9 domains allowed by the Internal Revenue Service.

JAMA Netw Open. 2020;3(10):e2021898. doi:10.1001/jamanetworkopen.2020.21898
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HEALTH POLICY

Transparency and Accountability of Medicaid Section 1115 Waiver Demonstration Programs Under the Affordable Care Act

This cross-sectional study examines US states’ compliance with both Patient Protection and Affordable Care Act demonstration program annual reporting and Medicaid guidelines for Section 1115 experimental program evaluations.

JAMA Netw Open. 2020;3(10):e2022035. doi:10.1001/jamanetworkopen.2020.22035
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HEALTH INFORMATICS

Characteristics of Patients Using Patient-Facing Application Programming Interface Technology at a US Health Care System

This case-control study investigates the characteristics of patients who use application programming interfaces connected to personal electronic devices to access electronic health information at a single US health care system.

JAMA Netw Open. 2020;3(10):e2022408. doi:10.1001/jamanetworkopen.2020.22408
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OCCUPATIONAL HEALTH

Association of Sleep Disorders With Physician Burnout

This cross-sectional study evaluates the association between sleep disorders and burnout symptoms among faculty and staff at a large teaching hospital.

JAMA Netw Open. 2020;3(10):e2023256. doi:10.1001/jamanetworkopen.2020.23256
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INFECTIOUS DISEASES

Trends in Appendicitis and Perforated Appendicitis Prevalence in Children in the United States, 2001-2015

This sequential, cross-sectional study examines the prevalence of perforated appendicitis in children in the United States in relation to access to health care from 2001 to 2015.

JAMA Netw Open. 2020;3(10):e2023484. doi:10.1001/jamanetworkopen.2020.23484
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INFECTIOUS DISEASES

Seropositive Prevalence of Antibodies Against SARS-CoV-2 in Wuhan, China

This cross-sectional study examines the seropositive prevalence of antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan, China, by sex and age group.

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JAMA Netw Open. 2020;3(10):e2025717. doi:10.1001/jamanetworkopen.2020.25717
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open access Correction

Numeric Errors in Figure 3

JAMA Netw Open. 2020;3(10):e2024427. doi:10.1001/jamanetworkopen.2020.24427
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Errors in Table 3 and Table 4

JAMA Netw Open. 2020;3(10):e2026150. doi:10.1001/jamanetworkopen.2020.26150
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Error in Methods

JAMA Netw Open. 2020;3(10):e2026185. doi:10.1001/jamanetworkopen.2020.26185
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Errors in Figure

JAMA Netw Open. 2020;3(10):e2026259. doi:10.1001/jamanetworkopen.2020.26259
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Error in Figure 1

JAMA Netw Open. 2020;3(10):e2026464. doi:10.1001/jamanetworkopen.2020.26464
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Omission in Funding/Support

JAMA Netw Open. 2020;3(10):e2027727. doi:10.1001/jamanetworkopen.2020.27727
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open access JAMA Network Open Masthead

JAMA Network Open

JAMA Netw Open. 2020;3(10):e2024455. doi:10.1001/jamanetworkopen.2020.24455
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