ONCOLOGY
Shaan Dudani, MBChB; Guillermo de Velasco, MD; J. Connor Wells, MD; et al.
This cohort study evaluates the prevalence of metastasis sites for clear cell, papillary, and chromophobe renal cell carcinoma (RCC) and examines the association between site of metastasis and overall survival.
JAMA Netw Open. 2021;4(1):e2021869. doi:10.1001/jamanetworkopen.2020.21869
HEALTH POLICY
Wesley H. Greenblatt, MD
This cross-sectional study uses Massachusetts medical licensure and business registration records to examine the proportion of physician-founded companies and the types of businesses started.
JAMA Netw Open. 2021;4(1):e2026938. doi:10.1001/jamanetworkopen.2020.26938
HEALTH POLICY
Bruce E. Landon, MD, MBA; Jukka-Pekka Onnela, PhD; Laurie Meneades, MA; et al.
This cross-sectional study examines whether differences exist between Black and White Medicare beneficiaries in the observed patterns of patient sharing between primary care physicians and physicians in the 6 specialties to which patients were most frequently referred.
JAMA Netw Open. 2021;4(1):e2029238. doi:10.1001/jamanetworkopen.2020.29238
NEUROLOGY
Alberto Benussi, MD; Enrico Premi, MD; Stefano Gazzina, MD; et al.
This cohort study uses data from tertiary frontotemporal dementia research clinics across Europe and Canada to assess the frequency and severity of behavioral symptoms and their progression in different forms of genetic frontotemporal dementia.
JAMA Netw Open. 2021;4(1):e2030194. doi:10.1001/jamanetworkopen.2020.30194
OBSTETRICS AND GYNECOLOGY
Jung Eun Yoo, MD, PhD; Dong Wook Shin, MD, DrPH, MBA; Kyungdo Han, PhD; et al.
This cohort study uses data from the Korean National Health Insurance System database to investigate whether female reproductive factors are associated with fractures among postmenopausal women in Korea.
JAMA Netw Open. 2021;4(1):e2030405. doi:10.1001/jamanetworkopen.2020.30405
CARDIOLOGY
Hyacinth I. Hyacinth, MD, PhD, MPH; Nora Franceschini, MD, MPH; Samantha R. Seals, PhD; et al.
This cohort study evaluates whether African American individuals with sickle cell trait have a higher incidence of myocardial infarction or composite coronary heart disease outcomes compared with those without sickle cell trait.
JAMA Netw Open. 2021;4(1):e2030435. doi:10.1001/jamanetworkopen.2020.30435
MEDICAL EDUCATION
Jennifer A. Rymer, MD, MBA; Camille G. Frazier-Mills, MD, MHS; Larry R. Jackson II, MD, MHS; et al.
This quality improvement study assess a systematic recruitment initiative aimed at ensuring adequate matriculation of women and underrepresented racial and ethnic groups in a general cardiology fellowship.
JAMA Netw Open. 2021;4(1):e2030832. doi:10.1001/jamanetworkopen.2020.30832
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Invited Commentary
Dismantling Structural Discrimination in Cardiology Fellowship Recruitment
Joyce Njoroge, MD; Fatima Rodriguez, MD, MPH; Michelle A. Albert, MD, MPH
JAMA Netw Open
DIABETES AND ENDOCRINOLOGY
Nestoras N. Mathioudakis, MD, MHS; Mohammed S. Abusamaan, MD, MPH; Ahmed F. Shakarchi, MBChB, MPH; et al.
This cohort study of hospitalized patients uses a machine learning model to predict the risk of iatrogenic hypoglycemia within 24 hours after blood glucose measurement during hospitalization.
JAMA Netw Open. 2021;4(1):e2030913. doi:10.1001/jamanetworkopen.2020.30913
NEPHROLOGY
Jon N. Marsh, PhD; Ta-Chiang Liu, MD, PhD; Parker C. Wilson, MD, PhD; et al.
This prognostic study compares performances between pathologists and a deep learning model to quantify percent global glomerulosclerosis on images of kidney biopsy specimens and assesses the potential benefit of the model on donor kidney discard rates.
JAMA Netw Open. 2021;4(1):e2030939. doi:10.1001/jamanetworkopen.2020.30939
SUBSTANCE USE AND ADDICTION
Pamela C. Griesler, PhD; Mei-Chen Hu, PhD; Melanie M. Wall, PhD; et al.
This cross-sectional study examines the associations between parental and adolescent prescription opioid medical use and misuse among parent and adolescent dyads in the National Survey on Drug Use and Health.
JAMA Netw Open. 2021;4(1):e2031073. doi:10.1001/jamanetworkopen.2020.31073
INFECTIOUS DISEASES
Talia M. Nir, PhD; Jean-Paul Fouche, PhD; Jintanat Ananworanich, MD, PhD; et al.
This cross-sectional study examines structural brain associations with CD4+ T-cell count and viral load in HIV-positive individuals taking and not taking combination antiretroviral therapy.
JAMA Netw Open. 2021;4(1):e2031190. doi:10.1001/jamanetworkopen.2020.31190
INFECTIOUS DISEASES
Kenneth E. Schmader, MD; Christine K. Liu, MD, MSc; Theresa Harrington, MD, MPH&TM; et al.
This randomized clinical trial assesses whether injection-site pain and reactogenicity are noninferior in trivalent adjuvanted inactivated influenza vaccine (aIIV3) compared with trivalent high-dose inactivated influenza vaccine (HD-IIV3) among adults aged 65 years and older.
JAMA Netw Open. 2021;4(1):e2031266. doi:10.1001/jamanetworkopen.2020.31266
NEUROLOGY
Nina Beker, PhD; Andrea Ganz, MSc; Marc Hulsman, PhD; et al.
This cohort study examines trajectories of cognitive function and their associations with cognitive reserve, physical health, and postmortem levels of neuropathology associated with Alzheimer disease in Dutch centenarians.
JAMA Netw Open. 2021;4(1):e2031654. doi:10.1001/jamanetworkopen.2020.31654
ONCOLOGY
Xu Guan, MD, PhD; Ran Wei, MD; Runkun Yang, MD; et al.
This cohort study assesses the association between radiotherapy and the risk of individual types of second gynecological malignant neoplasms in patients with rectal cancer and estimates survival outcomes for patients with secondary cancers.
JAMA Netw Open. 2021;4(1):e2031661. doi:10.1001/jamanetworkopen.2020.31661
CARDIOLOGY
Zhuxian Zhang, MD; Mengyi Liu, MD; Chun Zhou, MD; et al.
This cohort study of a large nationwide database of Chinese adults assesses the association between dietary niacin intake and the risk of new-onset hypertension.
JAMA Netw Open. 2021;4(1):e2031669. doi:10.1001/jamanetworkopen.2020.31669
HEALTH INFORMATICS
Jean Coquet, PhD; Nicolas Bievre, MS; Vincent Billaut, MS; et al.
This cohort study assesses the performance of a prognostic survival model derived from randomized clinical trial data when the model is applied to real-world data from the electronic health records of patients with metastatic castration-resistant prostate cancer.
JAMA Netw Open. 2021;4(1):e2031730. doi:10.1001/jamanetworkopen.2020.31730
PULMONARY MEDICINE
Yi-Han Jhuang, MD; Chi-Hsiang Chung, PhD; I-Duo Wang, MD; et al.
This case-control study examines the demographic variables, comorbidities, exposure to obstructive sleep apnea, and obstructive sleep apnea therapies in adult men with or without an infertility diagnosis.
JAMA Netw Open. 2021;4(1):e2031846. doi:10.1001/jamanetworkopen.2020.31846
HEALTH INFORMATICS
Tracy A. Lieu, MD, MPH; E. Margaret Warton, MPH; Jeffrey A. East, MD; et al.
This cross-sectional study examines primary care physicians’ frequency of attention switching associated with electronic inbox work and identifies potentially modifiable factors associated with attention switching and inbox work duration.
JAMA Netw Open. 2021;4(1):e2031856. doi:10.1001/jamanetworkopen.2020.31856
SUBSTANCE USE AND ADDICTION
Nicole L. Nollen, PhD; Jasjit S. Ahluwalia, MD; Lisa Sanderson Cox, PhD; et al.
This secondary analysis of the Evaluating Adverse Events in a Global Smoking Cessation Study (EAGLES) randomized clinical trial compares the pharmacotherapy efficacy of varenicline, bupropion, and nicotine replacement therapy in quitting smoking for Black vs White US smokers.
JAMA Netw Open. 2021;4(1):e2032053. doi:10.1001/jamanetworkopen.2020.32053
ENVIRONMENTAL HEALTH
Neal L. Fann, MPP; Christopher G. Nolte, PhD; Marcus C. Sarofim, PhD; et al.
This modeling study uses 2 climate models and under 2 air pollutant emission scenarios to model the associations between future changes in climate, air quality, and human health.
JAMA Netw Open. 2021;4(1):e2032064. doi:10.1001/jamanetworkopen.2020.32064
ONCOLOGY
Holli A. Loomans-Kropp, PhD, MPH; Paul Pinsky, PhD; Asad Umar, DVM, PhD
This cohort study investigates the association of aspirin use with risk of developing new cancers and site-specific cancer-associated survival in bladder, breast, esophageal, gastric, pancreatic, and uterine cancers.
JAMA Netw Open. 2021;4(1):e2032072. doi:10.1001/jamanetworkopen.2020.32072
PUBLIC HEALTH
Maureen R. Benjamins, PhD; Abigail Silva, PhD, MPH; Nazia S. Saiyed, MPH; et al.
This cross-sectional study examines city-level data from the 30 most populous US cities regarding all-cause mortality rates and racial inequities within cities and seeks to determine whether these measures changed during the past decade.
JAMA Netw Open. 2021;4(1):e2032086. doi:10.1001/jamanetworkopen.2020.32086
SURGERY
Louise Y. Sun, MD, SM; Jillian Rodger, BSc; Lisa Duffett, MD, MSc; et al.
This qualitative study attempts to derive patient-defined adverse cardiovascular and noncardiovascular events through a modified Delphi consensus-based process involving panel discussions with patients and their caregivers and clinicians.
JAMA Netw Open. 2021;4(1):e2032095. doi:10.1001/jamanetworkopen.2020.32095
HEALTH POLICY
Daniel O. Erim, MD, PhD, MSc; Gbemisola A. Oke, BDS, MPH, PhD; Akinyele O. Adisa, BDS; et al.
This cross-sectional study uses data from smartphone users to examine the association of government-mandated closures and restrictions with aggregate mobility and the association of changes in mobility with confirmed SARS-CoV-2 infections in Nigeria.
has active quiz
JAMA Netw Open. 2021;4(1):e2032101. doi:10.1001/jamanetworkopen.2020.32101
PEDIATRICS
Elliott Mark Weiss, MD, MSME; Aleksandra E. Olszewski, MD; Katherine F. Guttmann, MD, MBE; et al.
This survey study compared parents who chose to participate in a neonatal clinical trial with those who declined, assessing differences in demographic characteristics, opinions on the severity of their child’s medical condition, and levels of trust in medical researchers.
JAMA Netw Open. 2021;4(1):e2032106. doi:10.1001/jamanetworkopen.2020.32106
HEALTH POLICY
Elizabeth Schniedewind, EdD; Ryan P. Lindsay, PhD, MPH; Steven Snow, MA
This cross-sectional study compares the rate at which patients who are deaf are offered primary care medical or dental appointments with the rate at which appointments are offered to patients who can hear.
JAMA Netw Open. 2021;4(1):e2032207. doi:10.1001/jamanetworkopen.2020.32207
OPHTHALMOLOGY
Allen O. Eghrari, MD, MPH; Rachel J. Bishop, MD, MPH; Robin D. Ross, MD, MPH; et al.
This cross-sectional analysis of compares rates of ocular sequelae in antibody-positive survivors of Ebola virus disease and antibody-negative close contacts.
JAMA Netw Open. 2021;4(1):e2032216. doi:10.1001/jamanetworkopen.2020.32216
IMAGING
Anna Xu, BS; Bart Larsen, PhD; Alina Henn, MS; et al.
This meta-analysis assesses differential brain responses to noxious stimuli in patients with chronic pain using functional magnetic resonance imaging while adhering to current best practices for neuroimaging meta-analyses.
JAMA Netw Open. 2021;4(1):e2032236. doi:10.1001/jamanetworkopen.2020.32236
IMAGING
Yuming Jiang, MD, PhD; Xiaokun Liang, PhD; Wei Wang, MD; et al.
This cohort study assesses the use of a deep learning model for predicting occult peritoneal metastasis based on preoperative computed tomographic images in patients with gastric cancer.
JAMA Netw Open. 2021;4(1):e2032269. doi:10.1001/jamanetworkopen.2020.32269
ONCOLOGY
Kexun Zhou, MBBS; Huashan Shi, MD; Ruqin Chen, MB; et al.
This cohort study investigates the associations of race, socioeconomic factors, and treatment characteristics with overall survival (OS) among patients with limited-stage small cell lung cancer (SCLC).
JAMA Netw Open. 2021;4(1):e2032276. doi:10.1001/jamanetworkopen.2020.32276
EMERGENCY MEDICINE
Stig Nikolaj Blomberg, MsC; Helle Collatz Christensen, MD, PhD; Freddy Lippert, MD; et al.
This randomized clinical trial examines how a machine learning model trained to identify out-of-hospital cardiac arrest and alert dispatchers during emergency calls affected the recognition of and response to out-of-hospital cardiac arrests.
JAMA Netw Open. 2021;4(1):e2032320. doi:10.1001/jamanetworkopen.2020.32320
GASTROENTEROLOGY AND HEPATOLOGY
Choong-Kyun Noh, MD, PhD; Eunyoung Lee, MS; Gil Ho Lee, MD; et al.
This cohort study compares the numbers of endoscopic examinations for gastric cancer screening over quarters of a calendar year with rates of gastric cancer diagnosed during those periods.
JAMA Netw Open. 2021;4(1):e2032542. doi:10.1001/jamanetworkopen.2020.32542
MEDICAL EDUCATION
Erik Brodt, MD; Steele Valenzuela, MS; Allison Empey, MD; et al.
This cohort study uses interrupted time series regression to assess the association between changes in race/ethnicity data collection in the American Medical College Application System survey and trends in applicants, matriculants, and graduates self-reporting as American Indian and Alaska Native.
JAMA Netw Open. 2021;4(1):e2032550. doi:10.1001/jamanetworkopen.2020.32550
HEALTH POLICY
Heidi Allen, PhD, MSW; Sarah H. Gordon, PhD, MS; Dennis Lee, BA; et al.
This cross-sectional study uses data from 3 state agencies merging comprehensive insurance claims with income eligibility data for Colorado Medicaid expansion and Marketplace enrollees to investigate health care utilization, cost, and quality between public and private health insurance for low-income adults.
JAMA Netw Open. 2021;4(1):e2032669. doi:10.1001/jamanetworkopen.2020.32669
SURGERY
Carter C. Lebares, MD; Anya L. Greenberg, MBA; Nancy L. Ascher, MD, PhD; et al.
This mixed-methods study explores individual and workplace factors that are associated with surgical trainees’ well-being, differences by gender identity, and end-user perceptions of experience.
JAMA Netw Open. 2021;4(1):e2032676. doi:10.1001/jamanetworkopen.2020.32676
SURGERY
Thomas Ashley, MD; Hannah Ashley, MD; Andreas Wladis, MD, PhD; et al.
This randomized clinical trial examined outcomes of inguinal hernia surgery performed by associate clinicians vs nonspecialist medical doctors among men in Sierra Leone.
JAMA Netw Open. 2021;4(1):e2032681. doi:10.1001/jamanetworkopen.2020.32681
PUBLIC HEALTH
Adam M. Leventhal, PhD; Danielle R. Madden, PhD; Natalia Peraza, BS; et al.
This randomized clinical trial assessed whether controlled exposure to e-cigarette puffs with salt vs free-base nicotine formulations improved the appeal and sensory experience of vaping among adult current nicotine or tobacco product users.
JAMA Netw Open. 2021;4(1):e2032757. doi:10.1001/jamanetworkopen.2020.32757
PEDIATRICS
Signe Hald Andersen, PhD
This cohort study examines the association between age at exposure to household dysfunction during childhood and adolescence and outcomes in early adulthood.
JAMA Netw Open. 2021;4(1):e2032769. doi:10.1001/jamanetworkopen.2020.32769
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Invited Commentary
Critical Periods in Child Development and the Transition to Adulthood
Gloria Huei-Jong Graf, MPH; Pietro Biroli, PhD; Daniel W. Belsky, PhD
JAMA Netw Open
PEDIATRICS
Kari Risnes, MD, PhD; Josephine Funck Bilsteen, MSc; Paul Brown, PhD; et al.
This cohort study examines the risk of all-cause and noncommunicable disease deaths among young adults born preterm and early term in 4 Nordic countries.
JAMA Netw Open. 2021;4(1):e2032779. doi:10.1001/jamanetworkopen.2020.32779
HEALTH POLICY
Alexander A. Brescia, MD, MSc; Tessa M. F. Watt, MD, MSc; Francis D. Pagani, MD, PhD; et al.
This cohort study estimates the proportion of recipients of durable left ventricular assist devices (LVADs) who are ineligible for clinical trial participation and assesses whether an association exists between ineligibility and mortality.
JAMA Netw Open. 2021;4(1):e2032865. doi:10.1001/jamanetworkopen.2020.32865
CARDIOLOGY
Enrico Baldi, MD; Sebastian Schnaubelt, MD; Maria Luce Caputo, MD; et al.
This cohort study evaluates the association between the time from the return of spontaneous circulation to electrocardiogram (ECG) acquisition and the diagnostic accuracy of ECG for ST-segment elevation myocardial infarction in patients who experience out-of-hospital cardiac arrest.
JAMA Netw Open. 2021;4(1):e2032875. doi:10.1001/jamanetworkopen.2020.32875
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Invited Commentary
Delaying Electrocardiography in Cardiac Arrest: A Pause for the Cause
Rajat Kalra, MD; Demetris Yannopoulos, MD
JAMA Netw Open
NEUROLOGY
Jinluan Chen, MSc; Sanne S. Mooldijk, BSc; Silvan Licher, MD, MSc; et al.
This cohort study examines the association of advanced glycation end products and their receptor with dementia in the general Dutch population.
JAMA Netw Open. 2021;4(1):e2033012. doi:10.1001/jamanetworkopen.2020.33012
DIABETES AND ENDOCRINOLOGY
Theodora Oikonomidi, MSc; Philippe Ravaud, PhD; Emmanuel Cosson, PhD; et al.
This survey study identifies the minimum effectiveness patients with type 1 and type 2 diabetes report they require to adopt 36 different remote digital diabetes monitoring scenarios.
JAMA Netw Open. 2021;4(1):e2033115. doi:10.1001/jamanetworkopen.2020.33115
EMERGENCY MEDICINE
Karen Alstrup, MD, PhD; Leif Rognås, MD, PhD; Stephen Sollid, MD, PhD; et al.
This cohort study assesses whether emergency medical transportation by helicopter vs by ground is associated with differences in mortality among patients in Denmark.
JAMA Netw Open. 2021;4(1):e2033318. doi:10.1001/jamanetworkopen.2020.33318
HEALTH POLICY
Vicki Fung, PhD; Mary Price, MA; Peter Hull, PhD; et al.
This cohort study evaluates whether the Affordable Care Act’s increase in Medicaid fees to Medicare levels for primary care practitioners was associated with increases in primary care visits for dual-eligible Medicare and Medicaid beneficiaries.
JAMA Netw Open. 2021;4(1):e2033424. doi:10.1001/jamanetworkopen.2020.33424
NUTRITION, OBESITY, AND EXERCISE
Nina Kaegi-Braun, MD; Marlena Mueller; Philipp Schuetz, MD, MPH; et al.
This cohort study examines the association of nutritional support with mortality rates among hospitalized patients with malnutrition in Switzerland.
JAMA Netw Open. 2021;4(1):e2033433. doi:10.1001/jamanetworkopen.2020.33433
ONCOLOGY
Kishan K. Patel, BS; Stacey Stein, MD; Jill Lacy, MD; et al.
This economic evaluation uses Markov modeling to identify and compare the cost and utility of doublet and standard treatments for patients with BRAF V600E variant colorectal cancer.
JAMA Netw Open. 2021;4(1):e2033441. doi:10.1001/jamanetworkopen.2020.33441
PUBLIC HEALTH
Leah S. Richmond-Rakerd, PhD; Stephanie D’Souza, PhD; Barry J. Milne, PhD; et al.
This cohort study uses data from the New Zealand Integrated Data Infrastructure database to examine the association of mental disorders with subsequent physical diseases and mortality among the New Zealand population over a 30-year observation period.
JAMA Netw Open. 2021;4(1):e2033448. doi:10.1001/jamanetworkopen.2020.33448
NUTRITION, OBESITY, AND EXERCISE
Steven B. Heymsfield, MD; Laura A. Coleman, PhD, RD; Ram Miller, MD; et al.
This randomized clinical trial evaluates the efficacy and safety of bimagrumab on body composition and glycemic control in adults with type 2 diabetes and overweight or obesity.
JAMA Netw Open. 2021;4(1):e2033457. doi:10.1001/jamanetworkopen.2020.33457
PUBLIC HEALTH
Nicole Kravitz-Wirtz, PhD, MPH; Amanda Aubel, MPH; Julia Schleimer, MPH; et al.
This survey study describes individuals’ concerns regarding violence in the context of the coronavirus disease 2019 (COVID-19) pandemic, experiences of pandemic-related unfair treatment, prevalence of and reasons for firearm acquisition, and changes in firearm storage practices due to the pandemic.
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JAMA Netw Open. 2021;4(1):e2033484. doi:10.1001/jamanetworkopen.2020.33484
PSYCHIATRY
Kairi Kõlves, PhD; Cecilie Fitzgerald, BM; Merete Nordentoft, DMSc; et al.
This cohort study uses national register data to analyze whether people with ASD have higher rates of suicide attempt and suicide compared with people without ASD, identify potential risk factors for suicide attempts and suicide among those with ASD, and examine associations with comorbid disorders.
JAMA Netw Open. 2021;4(1):e2033565. doi:10.1001/jamanetworkopen.2020.33565
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Invited Commentary
Death by Suicide Among People With Autism: Beyond Zebrafish
Mikle South, PhD; Andreia P. Costa, PhD; Carly McMorris, PhD
JAMA Netw Open
INFECTIOUS DISEASES
Frederick J. Angulo, DVM, PhD; Lyn Finelli, DrPH, MS; David L. Swerdlow, MD
This cross-sectional study assesses the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease burden in the US, using surveillance data and seroprevalence surveys to estimate the number of SARS-CoV-2 infections, symptomatic infections, hospitalizations, and deaths through November 15, 2020.
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JAMA Netw Open. 2021;4(1):e2033706. doi:10.1001/jamanetworkopen.2020.33706
PEDIATRICS
Jennifer R. Marin, MD, MSc; Jonathan Rodean, MPP; Matt Hall, PhD; et al.
This cross-sectional study assesses the racial and ethnic differences in the performance of common emergency department imaging studies and examines patterns across diagnoses among US children’s hospitals.
JAMA Netw Open. 2021;4(1):e2033710. doi:10.1001/jamanetworkopen.2020.33710
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Invited Commentary
Racial Inequities in Pediatric Emergency Care
Anupam B. Kharbanda, MD, MSc
JAMA Netw Open
STATISTICS AND RESEARCH METHODS
Chi-leung Chiang, FRCR; Sik-kwan Chan, BSc; Shing-fung Lee, FRCR; et al.
This economic evaluation analyzes the cost-effectiveness of pembrolizumab as a second-line treatment in patients with advanced hepatocellular carcinoma.
JAMA Netw Open. 2021;4(1):e2033761. doi:10.1001/jamanetworkopen.2020.33761
PUBLIC HEALTH
Thomas J. Reese, PharmD, PhD; Chelsey R. Schlechter, PhD, MPH; Lindsey N. Potter, PhD; et al.
This cross-sectional study assesses the changes associated with the revised US Preventive Services Task Force guideline with lung cancer screening eligibility among female, Black, and Hispanic populations using a large nationwide survey.
JAMA Netw Open. 2021;4(1):e2033769. doi:10.1001/jamanetworkopen.2020.33769
ONCOLOGY
Nataniel H. Lester-Coll, MD; Steven Ades, MD, MSc; James B. Yu, MD, MHS; et al.
This economic evaluation assesses the cost-effectiveness of the addition of prostate radiation therapy to androgen deprivation therapy for men with low-volume metastatic hormone-sensitive prostate cancer.
JAMA Netw Open. 2021;4(1):e2033787. doi:10.1001/jamanetworkopen.2020.33787
SURGERY
Miao Cai, PhD; Yan Xie, MPH; Benjamin Bowe, MPH; et al.
This cohort study examines temporal trends and risk factors associated with lower extremity amputation among veterans using Veterans Health Administration services.
JAMA Netw Open. 2021;4(1):e2033953. doi:10.1001/jamanetworkopen.2020.33953
ONCOLOGY
Arianna Heyer, BA; Rachel E. Granberg, BA; Kristin L. Rising, MD, MSHP; et al.
This qualitative study surveyed physicians and other health professionals working in oncology to determine the perceived advantages and disadvantages of telehealth video visits in cancer care.
JAMA Netw Open. 2021;4(1):e2033967. doi:10.1001/jamanetworkopen.2020.33967
HEALTH POLICY
Valentin Danchev, DPhil; Yan Min, MD; John Borghi, PhD; et al.
This cross-sectional study evaluates the implementation of the International Committee of Medical Journal Editors (ICMJE) data sharing statement requirement in 3 leading medical journals.
JAMA Netw Open. 2021;4(1):e2033972. doi:10.1001/jamanetworkopen.2020.33972
GERIATRICS
Julia Adler-Milstein, PhD; Katherine Raphael, BA; Terrence A. O’Malley, MD; et al.
This survey study evaluates the current state of the completeness, timeliness, and usability of information sharing, and identifies characteristics associated with better sharing, to support patient care transitions between hospitals and skilled nursing facilities.
JAMA Netw Open. 2021;4(1):e2033980. doi:10.1001/jamanetworkopen.2020.33980
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Invited Commentary
Bridging the Hospital-Skilled Nursing Facility Information Continuity Divide
Andrea Gilmore-Bykovskyi, PhD, RN; Laura Block, BS, BSN, RN; Amy J. H. Kind, MD, PhD
JAMA Netw Open
NEPHROLOGY
Leila R. Zelnick, PhD; Nicolae Leca, MD; Bessie Young, MD, MPH; et al.
This cohort study assesses the association between estimated glomerular filtration rate (eGFR) calculated with vs without a coefficient for race and time to achievement of an eGFR less than 20 mL/min/1.73 m2.
JAMA Netw Open. 2021;4(1):e2034004. doi:10.1001/jamanetworkopen.2020.34004
ONCOLOGY
Elizabeth J. Sutton, MD; Lior Z. Braunstein, MD; Mahmoud B. El-Tamer, MD; et al.
This nonrandomized controlled trial uses data from a single tertiary care center in the US to investigate the accuracy of magnetic resonance imaging (MRI)–guided biopsy compared with surgical resection for assessing pathologic complete response after neoadjuvant chemotherapy in patients with breast cancer.
JAMA Netw Open. 2021;4(1):e2034045. doi:10.1001/jamanetworkopen.2020.34045
GERIATRICS
Lillian Min, MD, MSHS; Jin-Kyung Ha, PhD; Carole E. Aubert, MD; et al.
This cross-sectional study develops and validates a method to more precisely quantify dose intensity of hypertension treatment using only health system administrative pharmacy fill data.
JAMA Netw Open. 2021;4(1):e2034059. doi:10.1001/jamanetworkopen.2020.34059
ONCOLOGY
John Ng, MD; Yael R. Stovezky; David J. Brenner, PhD; et al.
This decision analytical model presents a simplified mathematical model of tumor growth, control, and new metastases for cancers with varying doubling times and metastatic potential and estimates tumor control probability and metastases risk as a function of treatment delay interval.
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JAMA Netw Open. 2021;4(1):e2034065. doi:10.1001/jamanetworkopen.2020.34065
NEPHROLOGY
Christina Bradshaw, MD, MS; I-Chun Thomas, MS; Maria E. Montez-Rath, PhD; et al.
This cohort study examines which patient and facility factors in the US Department of Veterans Affairs health care system are associated with dialysis approaches and outcomes.
JAMA Netw Open. 2021;4(1):e2034084. doi:10.1001/jamanetworkopen.2020.34084
MEDICAL EDUCATION
Radoslav Zinoviev, MD, MBA; Harlan M. Krumholz, MD, SM; Kevin Pirruccio, BA; et al.
This economic evaluation examines graduate medical education funding, an annual subsidy awarded to academic hospitals, and whether it is associated with a hospital’s financial standing, clinical outcomes, or resident academic performance.
JAMA Netw Open. 2021;4(1):e2034196. doi:10.1001/jamanetworkopen.2020.34196
ONCOLOGY
Neha Sati, BSc; Devon J. Boyne, MSc, PhD; Winson Y. Cheung, MD, MPH; et al.
This systematic review and meta-analysis assesses trials that reported on factors associated with differential response to programmed cell death 1 and programmed cell death ligand 1 inhibitors among patients diagnosed with metastatic clear cell renal cell carcinoma and synthesizes the magnitude to which each factor was associated with the response to programmed cell death 1/programmed cell death ligand 1 inhibitors.
JAMA Netw Open. 2021;4(1):e2034201. doi:10.1001/jamanetworkopen.2020.34201
PUBLIC HEALTH
Dawn M. Bravata, MD; Anthony J. Perkins, MS; Laura J. Myers, PhD; et al.
This cohort study examines the association of patient caseload and demand with mortality among patients with coronavirus disease 2019 (COVID-19) in US Veterans Affairs (VA) intensive care units.
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has audio
JAMA Netw Open. 2021;4(1):e2034266. doi:10.1001/jamanetworkopen.2020.34266
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Audio Editors' Summary:
Asymptomatic SARS-CoV-2 Transmission; Association of ICU Volume with Patient Mortality During the COVID-19 Pandemic
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Invited Commentary
Intensive Care Unit Strain and Mortality Risk Among Critically Ill Patients With COVID-19—There Is No “Me” in COVID
Lewis Rubinson, MD, PhD
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JAMA Netw Open
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Audio Editors' Summary:
Asymptomatic SARS-CoV-2 Transmission; Association of ICU Volume with Patient Mortality During the COVID-19 Pandemic
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Audio Editors' Summary:
Asymptomatic SARS-CoV-2 Transmission; Association of ICU Volume with Patient Mortality During the COVID-19 Pandemic
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