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July 2022 - May 2018

Decade

Year

Issue

June 2021, Vol 4, No. 6

open access Original Investigation

HEALTH POLICY

Comparison of Adverse Events Among Home- vs Facility-Administered Biologic Infusions, 2007-2017

This cohort study of patients who received biologic infusions for immune-mediated diseases examines the association of infusions received at home with admission to the hospital or emergency department within the next day.

JAMA Netw Open. 2021;4(6):e2110268. doi:10.1001/jamanetworkopen.2021.10268
Abstract Full Text pdf link PDF

HEALTH POLICY

Access to Care, Cost of Care, and Satisfaction With Care Among Adults With Private and Public Health Insurance in the US

This survey study compares individual experiences related to access to care, costs of care, and reported satisfaction with care for the 5 major forms of health insurance coverage in the US.

JAMA Netw Open. 2021;4(6):e2110275. doi:10.1001/jamanetworkopen.2021.10275
Abstract Full Text pdf link PDF

ORTHOPEDICS

Association of Sex With Risk of 2-Year Revision Among Patients Undergoing Total Hip Arthroplasty

This cohort study evaluates the association between sex and 2-year revision after total hip arthroplasty as well as the association between sex and risk of revision.

JAMA Netw Open. 2021;4(6):e2110687. doi:10.1001/jamanetworkopen.2021.10687
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

Association of Simulated COVID-19 Vaccination and Nonpharmaceutical Interventions With Infections, Hospitalizations, and Mortality

This decision analytical study assesses the association of simulated COVID-19 vaccine efficacy and coverage scenarios with and without nonpharmaceutical interventions with infections, hospitalizations, and deaths.

has active quiz
JAMA Netw Open. 2021;4(6):e2110782. doi:10.1001/jamanetworkopen.2021.10782
Abstract Full Text pdf link PDF CME & MOC

PEDIATRICS

Underlying Medical Conditions Associated With Severe COVID-19 Illness Among Children

This cross-sectional study examines the risk of severe COVID-19 illness among children associated with underlying medical conditions and medical complexity.

has active quiz
JAMA Netw Open. 2021;4(6):e2111182. doi:10.1001/jamanetworkopen.2021.11182
Abstract Full Text pdf link PDF CME & MOC

PUBLIC HEALTH

Characteristics of e-Cigarette Use Behaviors Among US Youth, 2020

This survey study characterizes e-cigarette use behaviors among US youth in 2020 using data from the 2020 National Youth Tobacco Survey.

JAMA Netw Open. 2021;4(6):e2111336. doi:10.1001/jamanetworkopen.2021.11336
Abstract Full Text pdf link PDF

PSYCHIATRY

Evaluation of Attention-Deficit/Hyperactivity Disorder Medications, Externalizing Symptoms, and Suicidality in Children

This cohort study investigates the associations of attention-deficit/hyperactivity disorder (ADHD) medication with externalizing symptoms and childhood suicidality.

JAMA Netw Open. 2021;4(6):e2111342. doi:10.1001/jamanetworkopen.2021.11342
Abstract Full Text pdf link PDF

PEDIATRICS

Bilateral Chilblain-like Lesions of the Toes Characterized by Microvascular Remodeling in Adolescents During the COVID-19 Pandemic

This case series examines the association of chilblain-like lesions with SARS-CoV-2 infection.

has active quiz
JAMA Netw Open. 2021;4(6):e2111369. doi:10.1001/jamanetworkopen.2021.11369
Abstract Full Text pdf link PDF CME & MOC

HEALTH POLICY

Hospital-at-Home Interventions vs In-Hospital Stay for Patients With Chronic Disease Who Present to the Emergency Department: A Systematic Review and Meta-analysis

This meta-analysis investigates the association of hospital-at-home interventions vs in-hospital stay with patient outcomes in adults with chronic disease who present to an emergency department.

JAMA Netw Open. 2021;4(6):e2111568. doi:10.1001/jamanetworkopen.2021.11568
Abstract Full Text pdf link PDF

OBSTETRICS AND GYNECOLOGY

Use of Electronic Medical Records to Estimate Changes in Pregnancy and Birth Rates During the COVID-19 Pandemic

This cohort study of all pregnancies in a large US university health care system examines changes in birth volumes associated with the COVID-19 societal shutdown and models prospective trends for birth volume post–societal shutdown.

has active quiz
JAMA Netw Open. 2021;4(6):e2111621. doi:10.1001/jamanetworkopen.2021.11621
Abstract Full Text pdf link PDF CME & MOC

HEALTH POLICY

Trends in Venous Thromboembolism Anticoagulation in Patients Hospitalized With COVID-19

This cohort study of patients hospitalized with COVID-19 examines the association of anticoagulation treatment with mortality rates, and assesses differences between prophylactic- and treatment-doses in in-hospital and 60-day mortality.

has active quiz
JAMA Netw Open. 2021;4(6):e2111788. doi:10.1001/jamanetworkopen.2021.11788
Abstract Full Text pdf link PDF CME & MOC

INFECTIOUS DISEASES

Estimated Cardiorespiratory Hospitalizations Attributable to Influenza and Respiratory Syncytial Virus Among Long-term Care Facility Residents

This cohort study evaluates the incidence, cost, and length of hospitalizations associated with seasonal respiratory viruses from 2011 to 2017 among older adults who live in long-term care facilities.

JAMA Netw Open. 2021;4(6):e2111806. doi:10.1001/jamanetworkopen.2021.11806
Abstract Full Text pdf link PDF

HEALTH POLICY

Association of the 2016 US Centers for Disease Control and Prevention Opioid Prescribing Guideline With Changes in Opioid Dispensing After Surgery

This cross-sectional study assesses changes in postoperative opioid dispensing after vs before the US Centers for Disease Control and Prevention (CDC) guideline for prescribing opioids was released in March 2016.

JAMA Netw Open. 2021;4(6):e2111826. doi:10.1001/jamanetworkopen.2021.11826
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

Effect of Rapid Respiratory Virus Testing on Antibiotic Prescribing Among Children Presenting to the Emergency Department With Acute Respiratory Illness: A Randomized Clinical Trial

This randomized clinical trial evaluates whether rapid respiratory pathogen tests lead to decreased antibiotic use and health care use among children with influenzalike illness seen in an emergency department.

JAMA Netw Open. 2021;4(6):e2111836. doi:10.1001/jamanetworkopen.2021.11836
Abstract Full Text pdf link PDF

STATISTICS AND RESEARCH METHODS

Practices and Attitudes of Swiss Stakeholders Regarding Investigator-Initiated Clinical Trial Funding Acquisition and Cost Management

This qualitative study examines practices and attitudes regarding funding acquisition and cost management of investigator-initiated clinical trials among primary investigators, funders and sponsors, clinical trial support organizations, and ethics committee members in Switzerland.

JAMA Netw Open. 2021;4(6):e2111847. doi:10.1001/jamanetworkopen.2021.11847
Abstract Full Text pdf link PDF

GASTROENTEROLOGY AND HEPATOLOGY

Population-Based Long-term Cardiac-Specific Mortality Among Patients With Major Gastrointestinal Cancers

This cohort study examines the associations of major gastrointestinal cancers with cardiac-specific mortality.

JAMA Netw Open. 2021;4(6):e2112049. doi:10.1001/jamanetworkopen.2021.12049
Abstract Full Text pdf link PDF

PSYCHIATRY

Incidence of Early Police Contact Among Children With Emerging Mental Health Problems in Australia

This cohort study examines the behavioral, developmental, and other factors underlying the first exposure of school-aged children to the criminal justice system in Australia.

JAMA Netw Open. 2021;4(6):e2112057. doi:10.1001/jamanetworkopen.2021.12057
Abstract Full Text pdf link PDF

GERIATRICS

Association Between Receipt of Cancer Screening and All-Cause Mortality in Older Adults

This cohort study examines whether cancer screening is significantly associated with all-cause mortality in older adults after accounting for comorbidities and functional status.

JAMA Netw Open. 2021;4(6):e2112062. doi:10.1001/jamanetworkopen.2021.12062
Abstract Full Text pdf link PDF

ONCOLOGY

Association of Primary Treatment Modality for Advanced-Stage Oropharyngeal Squamous Cell Carcinoma With Survival Outcomes

This comparative effectiveness research investigates survival outcomes for chemoradiotherapy vs surgical treatment among patients with advanced-stage oropharyngeal squamous cell carcinoma.

JAMA Netw Open. 2021;4(6):e2112067. doi:10.1001/jamanetworkopen.2021.12067
Abstract Full Text pdf link PDF

ONCOLOGY

Characterization of Clinical Symptoms by Race Among Women With Early-Stage, Hormone Receptor–Positive Breast Cancer Before Starting Chemotherapy

This cohort study compares symptom burden among Black and White women with early-stage breast cancer before starting chemotherapy and assesses symptom differences associated with baseline characteristics.

JAMA Netw Open. 2021;4(6):e2112076. doi:10.1001/jamanetworkopen.2021.12076
Abstract Full Text pdf link PDF

PEDIATRICS

Efficacy of Smartphone Active and Passive Virtual Reality Distraction vs Standard Care on Burn Pain Among Pediatric Patients: A Randomized Clinical Trial

This randomized clinical trial evaluates the efficacy of a smartphone VR game vs standard care on dressing pain among pediatric patients with burns.

JAMA Netw Open. 2021;4(6):e2112082. doi:10.1001/jamanetworkopen.2021.12082
Abstract Full Text pdf link PDF

CARDIOLOGY

Use of Preventive Aspirin Among Older US Adults With and Without Diabetes

This cross-sectional study uses data from the National Health and Nutrition Examination Survey to assess the prevalence of aspirin use among older adults in the US with and without diabetes.

JAMA Netw Open. 2021;4(6):e2112210. doi:10.1001/jamanetworkopen.2021.12210
Abstract Full Text pdf link PDF

UROLOGY

Time Trends in Use of Radical Prostatectomy by Tumor Risk and Life Expectancy in a National Veterans Affairs Cohort

This cohort study investigates time trends in use of radical prostatectomy by tumor risk and Prostate Cancer Comorbidity Index score in a contemporary, nationally representative Veteran Affairs cohort.

JAMA Netw Open. 2021;4(6):e2112214. doi:10.1001/jamanetworkopen.2021.12214
Abstract Full Text pdf link PDF

MEDICAL JOURNALS AND PUBLISHING

Sex Differences in Academic Productivity Across Academic Ranks and Specialties in Academic Medicine: A Systematic Review and Meta-analysis

This systematic review and meta-analysis examines the available literature on sex differences in h-index, a measure of citation-related publication productivity, of academic faculty physicians across all medical specialties and all levels of academic rank.

JAMA Netw Open. 2021;4(6):e2112404. doi:10.1001/jamanetworkopen.2021.12404
Abstract Full Text pdf link PDF

NUTRITION, OBESITY, AND EXERCISE

Effect of a Smartphone App on Weight Change and Metabolic Outcomes in Asian Adults With Type 2 Diabetes: A Randomized Clinical Trial

This randomized clinical trial of adults in Singapore with type 2 diabetes and overweight or obesity assessed whether use of a smartphone app with behavior modification strategies affected weight change and metabolic outcomes.

JAMA Netw Open. 2021;4(6):e2112417. doi:10.1001/jamanetworkopen.2021.12417
Abstract Full Text pdf link PDF

ONCOLOGY

Comparison of Joint and Landmark Modeling for Predicting Cancer Progression in Men With Castration-Resistant Prostate Cancer: A Secondary Post Hoc Analysis of the PREVAIL Randomized Clinical Trial

This prognostic study assessed the ability of dynamic prediction models to aid prognosis of radiographic progression risk among men with metastatic castration-resistant prostate cancer.

JAMA Netw Open. 2021;4(6):e2112426. doi:10.1001/jamanetworkopen.2021.12426
Abstract Full Text pdf link PDF

GERIATRICS

Peer-to-Peer Support and Changes in Health and Well-being in Older Adults Over Time

This cohort study compares health status, quality of life, and depressive and anxiety symptoms between older adults receiving peer-to-peer support vs those receiving standard community services.

JAMA Netw Open. 2021;4(6):e2112441. doi:10.1001/jamanetworkopen.2021.12441
Abstract Full Text pdf link PDF

SURGERY

Association of New Perioperative Benzodiazepine Use With Persistent Benzodiazepine Use

This cohort study examines the frequency of use and persistent use of benzodiazepines among patients undergoing major and minor surgical procedures.

JAMA Netw Open. 2021;4(6):e2112478. doi:10.1001/jamanetworkopen.2021.12478
Abstract Full Text pdf link PDF

NUTRITION, OBESITY, AND EXERCISE

Automated Behavioral Workplace Intervention to Prevent Weight Gain and Improve Diet: The ChooseWell 365 Randomized Clinical Trial

This randomized clinical trial tests the effectiveness of an automated behavioral intervention using employee cafeteria purchasing data to prevent weight gain and improve diet.

JAMA Netw Open. 2021;4(6):e2112528. doi:10.1001/jamanetworkopen.2021.12528
Abstract Full Text pdf link PDF

ONCOLOGY

Analysis of Survival Among Adults With Early-Onset Colorectal Cancer in the National Cancer Database

This cohort study compares the survival among individuals with early-onset vs later-onset colorectal cancer using data from the US National Cancer Database.

JAMA Netw Open. 2021;4(6):e2112539. doi:10.1001/jamanetworkopen.2021.12539
Abstract Full Text pdf link PDF

NEUROLOGY

Evaluation of Systolic Blood Pressure, Use of Aspirin and Clopidogrel, and Stroke Recurrence in the Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke Trial

This cohort study investigates whether dual antiplatelet therapy is associated with stroke recurrence among patients with or without elevated baseline systolic blood pressure in the Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) trial.

JAMA Netw Open. 2021;4(6):e2112551. doi:10.1001/jamanetworkopen.2021.12551
Abstract Full Text pdf link PDF

PEDIATRICS

Quantification of US Food and Drug Administration Premarket Approval Statements for High-Risk Medical Devices With Pediatric Age Indications

This cross-sectional study identifies and characterizes high-risk devices with pediatric age indications derived from US Food and Drug Administration (FDA) premarket approval statements.

JAMA Netw Open. 2021;4(6):e2112562. doi:10.1001/jamanetworkopen.2021.12562
Abstract Full Text pdf link PDF

HEALTH INFORMATICS

International Analysis of Electronic Health Records of Children and Youth Hospitalized With COVID-19 Infection in 6 Countries

This cohort study aims to describe international hospitalization trends and key epidemiological and clinical features of children and youth with COVID-19.

has active quiz
JAMA Netw Open. 2021;4(6):e2112596. doi:10.1001/jamanetworkopen.2021.12596
Abstract Full Text pdf link PDF CME & MOC

SURGERY

Comparison of 24-Month Outcomes After Treatment for Distal Radius Fracture: The WRIST Randomized Clinical Trial

This randomized clinical trial compares 24-month outcomes among older adults with distal radius fractures across 4 treatment groups: volar locking plates, external fixation (with or without pinning), percutaneous pinning, and casting.

JAMA Netw Open. 2021;4(6):e2112710. doi:10.1001/jamanetworkopen.2021.12710
Abstract Full Text pdf link PDF

MEDICAL EDUCATION

Medical Students’ Demographic Characteristics and Their Perceptions of Faculty Role Modeling of Respect for Diversity

This cross-sectional study uses data from the Association of American Medical Colleges’ 2016 and 2017 Medical School Graduation Questionnaire to examine whether medical students’ perceptions of faculty respect for diversity differ by students’ sex, race/ethnicity, sexual orientation, and age.

JAMA Netw Open. 2021;4(6):e2112795. doi:10.1001/jamanetworkopen.2021.12795
Abstract Full Text pdf link PDF

CARDIOLOGY

Prevalence of Angina Among Primary Care Patients With Coronary Artery Disease

This survey study examines the prevalence and frequency of angina among stable US outpatients with coronary artery disease.

JAMA Netw Open. 2021;4(6):e2112800. doi:10.1001/jamanetworkopen.2021.12800
Abstract Full Text pdf link PDF

HEALTH POLICY

Racial, Ethnic, and Gender Representation in Leadership Positions at National Cancer Institute–Designated Cancer Centers

This cross-sectional study examines racial, ethnic, and gender representation in leadership positions at National Cancer Institute (NCI)–designated cancer centers.

JAMA Netw Open. 2021;4(6):e2112807. doi:10.1001/jamanetworkopen.2021.12807
Abstract Full Text pdf link PDF

UROLOGY

Demographic Factors Associated With Non-Guideline–Based Treatment of Kidney Cancer in the United States

This cohort study investigates the association of sex, race/ethnicity, and insurance status with undertreatment and overtreatment of kidney cancer.

JAMA Netw Open. 2021;4(6):e2112813. doi:10.1001/jamanetworkopen.2021.12813
Abstract Full Text pdf link PDF

GENETICS AND GENOMICS

A Mendelian Randomization Approach Using 3-HMG-Coenzyme-A Reductase Gene Variation to Evaluate the Association of Statin-Induced Low-Density Lipoprotein Cholesterol Lowering With Noncardiovascular Disease Phenotypes

This cohort study uses a mendelian randomization approach with variants in the HMGCR gene to evaluate associations between statin therapy and noncardiovascular diseases.

JAMA Netw Open. 2021;4(6):e2112820. doi:10.1001/jamanetworkopen.2021.12820
Abstract Full Text pdf link PDF

NEPHROLOGY

Progression and Regression of Chronic Kidney Disease by Age Among Adults in a Population-Based Cohort in Alberta, Canada

This population-based cohort study assesses progression and regression of disease among adults with chronic kidney disease in Alberta, Canada.

JAMA Netw Open. 2021;4(6):e2112828. doi:10.1001/jamanetworkopen.2021.12828
Abstract Full Text pdf link PDF

MEDICAL EDUCATION

Exposure to Workplace Trauma and Posttraumatic Stress Disorder Among Intern Physicians

This cohort study examines the prevalence and associations of work-related trauma exposure and posttraumatic stress disorder among physician interns in US residency programs.

JAMA Netw Open. 2021;4(6):e2112837. doi:10.1001/jamanetworkopen.2021.12837
Abstract Full Text pdf link PDF

HEALTH POLICY

Patient and Hospital Factors Associated With Differences in Mortality Rates Among Black and White US Medicare Beneficiaries Hospitalized With COVID-19 Infection

This cohort study examines differences in COVID-19 hospital mortality rates between Black and White patients and assesses whether they reflect differences in patient characteristics by race or by the hospitals to which Black and White patients are admitted.

has active quiz
JAMA Netw Open. 2021;4(6):e2112842. doi:10.1001/jamanetworkopen.2021.12842
Abstract Full Text pdf link PDF CME & MOC

PUBLIC HEALTH

Associations of Race/Ethnicity and Food Insecurity With COVID-19 Infection Rates Across US Counties

This cross-sectional study investigates the associations of race/ethnicity and food insecurity with COVID-19 infection rates in US counties.

has active quiz
JAMA Netw Open. 2021;4(6):e2112852. doi:10.1001/jamanetworkopen.2021.12852
Abstract Full Text pdf link PDF CME & MOC

PUBLIC HEALTH

Risk Factors Associated With COVID-19 Outcomes Among People With Intellectual and Developmental Disabilities Receiving Residential Services

This cohort study examines risk factors associated with COVID-19 positivity and mortality rates among individuals with intellectual and developmental disabilities receiving residential support services in New York City.

has active quiz
JAMA Netw Open. 2021;4(6):e2112862. doi:10.1001/jamanetworkopen.2021.12862
Abstract Full Text pdf link PDF CME & MOC

PEDIATRICS

Association of Intellectual Disability With All-Cause and Cause-Specific Mortality in Sweden

This population-based cohort study evaluates the risks and prevalence of premature mortality in individuals with varying severity of intellectual disability in Sweden.

JAMA Netw Open. 2021;4(6):e2113014. doi:10.1001/jamanetworkopen.2021.13014
Abstract Full Text pdf link PDF

PSYCHIATRY

Associations of Suicidality Trends With Cannabis Use as a Function of Sex and Depression Status

This survey study assesses whether cannabis use and cannabis use disorder are associated with a higher prevalence of suicidality among young adults with or without depression and whether these associations vary by sex.

JAMA Netw Open. 2021;4(6):e2113025. doi:10.1001/jamanetworkopen.2021.13025
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

Association of Social and Behavioral Risk Factors With Mortality Among US Veterans With COVID-19

This cohort study examines the implications of inadequate housing; financial difficulty; and alcohol, tobacco, or substance use as well as race/ethnicity and other covariates for veterans with symptomatic SARS-CoV-2 infection or COVID-19.

has active quiz
JAMA Netw Open. 2021;4(6):e2113031. doi:10.1001/jamanetworkopen.2021.13031
Abstract Full Text pdf link PDF CME & MOC

ONCOLOGY

Association of Chemotherapy Timing in Pregnancy With Congenital Malformation

This cohort study assesses the association of gestational age at initiation of chemotherapy among pregnant women with cancer with congenital malformation rates among their offspring.

JAMA Netw Open. 2021;4(6):e2113180. doi:10.1001/jamanetworkopen.2021.13180
Abstract Full Text pdf link PDF

PHARMACY AND CLINICAL PHARMACOLOGY

Cardiovascular Outcomes and Mortality Associated With Discontinuing Statins in Older Patients Receiving Polypharmacy

This population-based cohort study assesses the clinical implications of discontinuing the use of statins while maintaining other drugs in a cohort of older patients receiving polypharmacy.

JAMA Netw Open. 2021;4(6):e2113186. doi:10.1001/jamanetworkopen.2021.13186
Abstract Full Text pdf link PDF

ONCOLOGY

Actual and Missed Opportunities for End-of-Life Care Discussions With Oncology Patients: A Qualitative Study

This qualitative study describes successful navigation and missed opportunities for end-of-life discussions, including advance care planning, palliative care, discontinuation of disease-directed treatment, hospice care, and after-death wishes, between oncologists and outpatients with advanced cancer.

JAMA Netw Open. 2021;4(6):e2113193. doi:10.1001/jamanetworkopen.2021.13193
Abstract Full Text pdf link PDF

PEDIATRICS

Estimated Survival and Major Comorbidities of Very Preterm Infants Discharged Against Medical Advice vs Treated With Intensive Care in China

This cohort study investigates neonatal outcomes of very preterm infants who are discharged against medical advice from neonatal intensive care units (NICUs) before complete care can be provided compared with infants who receive full intensive care treatment.

JAMA Netw Open. 2021;4(6):e2113197. doi:10.1001/jamanetworkopen.2021.13197
Abstract Full Text pdf link PDF

ONCOLOGY

Toxicity Profiles and Survival Outcomes Among Patients With Nonmetastatic Nasopharyngeal Carcinoma Treated With Intensity-Modulated Proton Therapy vs Intensity-Modulated Radiation Therapy

This cohort study compares toxic effects and oncologic outcomes among patients with newly diagnosed nonmetastatic nasopharyngeal carcinoma (NPC) when treated with intensity-modulated proton therapy (IMPT) vs intensity-modulated radiation therapy (IMRT) with or without chemotherapy.

JAMA Netw Open. 2021;4(6):e2113205. doi:10.1001/jamanetworkopen.2021.13205
Abstract Full Text pdf link PDF

HEALTH POLICY

Social Determinants of Health and Geographic Variation in Medicare per Beneficiary Spending

This cross-sectional study examines the association of social determinants of health with variation in Medicare per beneficiary spending at the county level.

JAMA Netw Open. 2021;4(6):e2113212. doi:10.1001/jamanetworkopen.2021.13212
Abstract Full Text pdf link PDF

PEDIATRICS

Association of Child Maltreatment With Risk of Death During Childhood in South Australia

This case-control study assesses the association of documented child protection concerns regarding child maltreatment with risk of death from infancy to 16 years of age in South Australia.

JAMA Netw Open. 2021;4(6):e2113221. doi:10.1001/jamanetworkopen.2021.13221
Abstract Full Text pdf link PDF

HEALTH POLICY

Characteristics of Clinical Studies Used for US Food and Drug Administration Supplemental Indication Approvals of Drugs and Biologics, 2017 to 2019

This cross-sectional study seeks to characterize pivotal trials supporting recent supplemental new indication approvals of drugs and biologics by the US Food and Drug Administration (FDA) and compares them with pivotal trials that supported these therapeutics’ original indication approvals.

JAMA Netw Open. 2021;4(6):e2113224. doi:10.1001/jamanetworkopen.2021.13224
Abstract Full Text pdf link PDF

CRITICAL CARE MEDICINE

Lived Experiences of Family Members of Patients With Severe COVID-19 Who Died in Intensive Care Units in France

This qualitative study describes the experiences of family members of patients who died of COVID-19 in intensive care units (ICUs) in France.

JAMA Netw Open. 2021;4(6):e2113355. doi:10.1001/jamanetworkopen.2021.13355
Abstract Full Text pdf link PDF

GERIATRICS

Association of Social Isolation of Long-term Care Facilities in the United States With 30-Day Mortality

This cross-sectional study examines the prevalence of long-term care (LTC) facilities in socially isolated neighborhoods in the US and assesses the 30-day mortality risk associated with residence in an LTC facility located in an area with a high level of social isolation.

JAMA Netw Open. 2021;4(6):e2113361. doi:10.1001/jamanetworkopen.2021.13361
Abstract Full Text pdf link PDF

NUTRITION, OBESITY, AND EXERCISE

Analysis of Repeated Measurements of Serum Carotenoid Levels and All-Cause and Cause-Specific Mortality in Japan

This cohort study investigates the association of serum carotenoid levels found using repeated measurements with all-cause, cancer, and cardiovascular disease mortality in Japanese adults.

JAMA Netw Open. 2021;4(6):e2113369. doi:10.1001/jamanetworkopen.2021.13369
Abstract Full Text pdf link PDF

GLOBAL HEALTH

Assessment of Studies of Quality Improvement Strategies to Enhance Outcomes in Patients With Cardiovascular Disease

This systematic and scoping review assesses evidence on the effectiveness and implementation of quality improvement strategies to improve outcomes in patients with cardiovascular disease (CVD).

JAMA Netw Open. 2021;4(6):e2113375. doi:10.1001/jamanetworkopen.2021.13375
Abstract Full Text pdf link PDF

HEALTH POLICY

Trends in Use of Prescription Nonsteroidal Anti-inflammatory Medications Before vs After Implementation of a Florida Law Restricting Opioid Prescribing for Acute Pain

This quality improvement study examines changes in the prescribing and use of prescription nonsteroidal anti-inflammatory drugs (NSAIDs) after implementation of a law restricting the prescription of opioids in Florida.

JAMA Netw Open. 2021;4(6):e2113383. doi:10.1001/jamanetworkopen.2021.13383
Abstract Full Text pdf link PDF

HEALTH POLICY

Association of Branded Prescription Drug Rebate Size and Patient Out-of-Pocket Costs in a Nationally Representative Sample, 2007-2018

This cross-sectional study investigates the association of branded prescription drug rebate size and patient out-of-pocket costs.

JAMA Netw Open. 2021;4(6):e2113393. doi:10.1001/jamanetworkopen.2021.13393
Abstract Full Text pdf link PDF

PSYCHIATRY

Temporal Trends in Suicidal Ideation and Attempts Among US Adolescents by Sex and Race/Ethnicity, 1991-2019

This cross-sectional study analyses temporal trends to assess changes in suicidal ideation and nonfatal suicide attempts among US adolescents from 1991 through 2019.

JAMA Netw Open. 2021;4(6):e2113513. doi:10.1001/jamanetworkopen.2021.13513
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Adolescents’ Experiences, Emotions, and Coping Strategies Associated With Exposure to Media-Based Vicarious Racism

This qualitative study examines adolescents’ responses to online and media-based vicarious racism exposure and explores coping strategies, particularly positive coping strategies, that may be used to combat negative emotions.

JAMA Netw Open. 2021;4(6):e2113522. doi:10.1001/jamanetworkopen.2021.13522
Abstract Full Text pdf link PDF

HEALTH POLICY

Association of a Sweetened Beverage Tax With Purchases of Beverages and High-Sugar Foods at Independent Stores in Philadelphia

This cross-sectional study assesses the association of a sweetened beverage tax imposed by the city of Philadelphia, Pennsylvania, with price changes on beverages in small independent retail stores and examines changes in purchases of sweetened beverages and high-sugar foods after implementation of the tax.

JAMA Netw Open. 2021;4(6):e2113527. doi:10.1001/jamanetworkopen.2021.13527
Abstract Full Text pdf link PDF

ONCOLOGY

Association of Cumulative Social Risk and Social Support With Receipt of Chemotherapy Among Patients With Advanced Colorectal Cancer

This survey study examines whether cumulative social risk is associated with lower receipt of chemotherapy among patients with advanced colorectal cancer (CRC) and whether social support moderates this association.

JAMA Netw Open. 2021;4(6):e2113533. doi:10.1001/jamanetworkopen.2021.13533
Abstract Full Text pdf link PDF

MEDICAL EDUCATION

Academic Medicine Faculty Perceptions of Work-Life Balance Before and Since the COVID-19 Pandemic

This survey study assesses the relationship of perceived work-life conflict with academic medicine faculty intention to leave, reduce employment to part time, or decline leadership opportunities since the COVID-19 pandemic.

has active quiz
JAMA Netw Open. 2021;4(6):e2113539. doi:10.1001/jamanetworkopen.2021.13539
Abstract Full Text pdf link PDF CME & MOC

PSYCHIATRY

Clinical Outcomes Following Acute Residential Psychiatric Treatment in Transgender and Gender Diverse Adolescents

This cohort study examines mental health outcomes before and after acute residential psychiatric treatment among adolescents who are transgender and gender diverse vs cisgender.

JAMA Netw Open. 2021;4(6):e2113637. doi:10.1001/jamanetworkopen.2021.13637
Abstract Full Text pdf link PDF

GERIATRICS

Association of Age-Related Hearing Impairment With Physical Functioning Among Community-Dwelling Older Adults in the US

This cohort study assesses the association between hearing impairment and decline in physical function in terms of balance and walking endurance in a group of community-dwelling older adults in the US.

JAMA Netw Open. 2021;4(6):e2113742. doi:10.1001/jamanetworkopen.2021.13742
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Analysis of Female Enrollment and Participant Sex by Burden of Disease in US Clinical Trials Between 2000 and 2020

This cross-sectional study uses data from clinical trials registered in ClinicalTrials.gov between 2000 and 2020 to assess the presence of clinical trial data according to sex, female burden of disease relative to female proportion of enrollees, and associations of disease category and study features with female proportion of enrollees.

JAMA Netw Open. 2021;4(6):e2113749. doi:10.1001/jamanetworkopen.2021.13749
Abstract Full Text pdf link PDF

MEDICAL EDUCATION

Comparison of Program-centric vs Student-centric National Resident Matching Algorithms

This cross-sectional study of randomized computer-generated data compares program-centric and student-centric algorithms for the National Resident Matching Program.

JAMA Netw Open. 2021;4(6):e2113769. doi:10.1001/jamanetworkopen.2021.13769
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Timing and Length of Nocturnal Sleep and Daytime Napping and Associations With Obesity Types in High-, Middle-, and Low-Income Countries

This cross-sectional study examines the associations of bedtime, sleep duration, and daytime napping with obesity in a multinational population.

JAMA Netw Open. 2021;4(6):e2113775. doi:10.1001/jamanetworkopen.2021.13775
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

Secondary Use of COVID-19 Symptom Incidence Among Hospital Employees as an Example of Syndromic Surveillance of Hospital Admissions Within 7 Days

This cohort study examines whether there is an association between data collected for suspected COVID-19 symptoms among hospital employees and COVID-19 hospitalizations within 7 days.

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JAMA Netw Open. 2021;4(6):e2113782. doi:10.1001/jamanetworkopen.2021.13782
Abstract Full Text pdf link PDF CME & MOC

GLOBAL HEALTH

Health and Economic Outcomes Associated With COVID-19 in Women at High Risk of HIV Infection in Rural Kenya

This survey study of women at high risk of HIV infection in a rural county of Kenya examines the association of COVID-19 lockdowns with declines in employment, income, and levels of food insecurity.

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JAMA Netw Open. 2021;4(6):e2113787. doi:10.1001/jamanetworkopen.2021.13787
Abstract Full Text pdf link PDF CME & MOC

PUBLIC HEALTH

Trends in Incidence and Transmission Patterns of COVID-19 in Valencia, Spain

This epidemiological cohort study describes the local transmission pattern of SARS-CoV-2 in Valencia, Spain.

JAMA Netw Open. 2021;4(6):e2113818. doi:10.1001/jamanetworkopen.2021.13818
Abstract Full Text pdf link PDF

CRITICAL CARE MEDICINE

Accuracy of the Sequential Organ Failure Assessment Score for In-Hospital Mortality by Race and Relevance to Crisis Standards of Care

This cohort study compares mortality among Black and White patients with equivalent Sequential Organ Failure Assessment (SOFA) Scores and their odds of death with equivalent priority in Crisis Standards of Care.

JAMA Netw Open. 2021;4(6):e2113891. doi:10.1001/jamanetworkopen.2021.13891
Abstract Full Text pdf link PDF

HEALTH POLICY

Availability of Cost-effectiveness Studies for Drugs With High Medicare Part D Expenditures

This cross-sectional study examines the availability and quality of published cost-effectiveness studies for drugs with the greatest Medicare Part D spending in 2016.

JAMA Netw Open. 2021;4(6):e2113969. doi:10.1001/jamanetworkopen.2021.13969
Abstract Full Text pdf link PDF

ORTHOPEDICS

Exploration of Overdose Risk Score and Postoperative Complications and Health Care Use After Total Knee Arthroplasty

This cohort study investigates the association of an overdose risk score with postoperative complications and health care use after total knee arthroplasty.

JAMA Netw Open. 2021;4(6):e2113977. doi:10.1001/jamanetworkopen.2021.13977
Abstract Full Text pdf link PDF

PEDIATRICS

Rates of Bronchopulmonary Dysplasia Following Implementation of a Novel Prevention Bundle

This quality improvement study assesses whether a consistent, systematic prevention system of care decreases the rate of bronchopulmonary dysplasia in very low-birth-weight infants with gestational age less than 33 weeks.

JAMA Netw Open. 2021;4(6):e2114140. doi:10.1001/jamanetworkopen.2021.14140
Abstract Full Text pdf link PDF

NUTRITION, OBESITY, AND EXERCISE

Effects of Longer Seated Lunch Time on Food Consumption and Waste in Elementary and Middle School–age Children: A Randomized Clinical Trial

This crossover trial evaluates eating and noneating behaviors of school-age children during 2 different lunch periods (10 minutes vs 20 minutes) in a simulated school cafeteria setting that served meals according to National School Lunch Program nutrition standards.

JAMA Netw Open. 2021;4(6):e2114148. doi:10.1001/jamanetworkopen.2021.14148
Abstract Full Text pdf link PDF

ONCOLOGY

Association of Copy Number Variation Signature and Survival in Patients With Serous Ovarian Cancer

This genetic association study examines the Cancer Genome Atlas database to assess for genome-wide survival associations agnostic to gene function among patients with serous ovarian cancer.

JAMA Netw Open. 2021;4(6):e2114162. doi:10.1001/jamanetworkopen.2021.14162
Abstract Full Text pdf link PDF

GASTROENTEROLOGY AND HEPATOLOGY

Identification and Validation of Plasma Metabolomic Signatures in Precancerous Gastric Lesions That Progress to Cancer

This cohort study examines plasma metabolomics in individuals with gastric lesions and gastric cancer to identify metabolite signatures that might serve as biomarkers for risk of progression of the lesions to cancer.

JAMA Netw Open. 2021;4(6):e2114186. doi:10.1001/jamanetworkopen.2021.14186
Abstract Full Text pdf link PDF

OBSTETRICS AND GYNECOLOGY

Assessment of All-Cause Cancer Incidence Among Individuals With Preeclampsia or Eclampsia During First Pregnancy

This cohort study uses data from the French hospital discharge database to assess the association between preeclampsia or eclampsia during first pregnancy and the risk of future cancer and some cancer-associated blood diseases among female participants with a first pregnancy between 2012 and 2019.

JAMA Netw Open. 2021;4(6):e2114486. doi:10.1001/jamanetworkopen.2021.14486
Abstract Full Text pdf link PDF

STATISTICS AND RESEARCH METHODS

Characteristics of Randomized Clinical Trials in Surgery From 2008 to 2020: A Systematic Review

This systematic review describes the characteristics of the design, conduct, and reporting of randomized clinical trials in 6 surgical specialties published between 2008 and 2020.

JAMA Netw Open. 2021;4(6):e2114494. doi:10.1001/jamanetworkopen.2021.14494
Abstract Full Text pdf link PDF

GASTROENTEROLOGY AND HEPATOLOGY

Optimal Intervals of Ultrasonography Screening for Early Diagnosis of Hepatocellular Carcinoma in Taiwan

This national comparative effectiveness research study estimates differences in life expectancy and quality-adjusted life expectancy for abdominal ultrasonography screening intervals from fewer than 6 months to longer than 3 years among patients at high risk of hepatocellular carcinoma in Taiwan.

JAMA Netw Open. 2021;4(6):e2114680. doi:10.1001/jamanetworkopen.2021.14680
Abstract Full Text pdf link PDF

GLOBAL HEALTH

Estimated Cost-effectiveness of Solar-Powered Oxygen Delivery for Pneumonia in Young Children in Low-Resource Settings

This economic evaluation assesses whether solar-powered oxygen delivery is a cost-effective intervention for children younger than 5 years with hypoxemia in low-resource settings.

JAMA Netw Open. 2021;4(6):e2114686. doi:10.1001/jamanetworkopen.2021.14686
Abstract Full Text pdf link PDF

NUTRITION, OBESITY, AND EXERCISE

Association of Funding and Meal Preparation Time With Nutritional Quality of Meals of Supplemental Nutritional Assistance Program Recipients

This study uses decision analytical modeling to evaluate the association of food purchase funding and meal preparation time with the nutritional quality of meals consumed by recipients of the Supplemental Nutrition Assistance Program.

JAMA Netw Open. 2021;4(6):e2114701. doi:10.1001/jamanetworkopen.2021.14701
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Characterization of Benign Breast Diseases and Association With Age, Hormonal Factors, and Family History of Breast Cancer Among Women in Sweden

This cohort study investigates the risk of benign breast diseases in women by age, hormonal breast cancer risk factors, and family history of breast cancer.

JAMA Netw Open. 2021;4(6):e2114716. doi:10.1001/jamanetworkopen.2021.14716
Abstract Full Text pdf link PDF

HEALTH POLICY

Variation in Health Care Access and Quality Among US States and High-Income Countries With Universal Health Insurance Coverage

This cross-sectional study compares age-specific health care access and quality scores for the US with high-income countries with universal health insurance coverage and compares scores among US states with varying insurance coverage.

JAMA Netw Open. 2021;4(6):e2114730. doi:10.1001/jamanetworkopen.2021.14730
Abstract Full Text pdf link PDF

OCCUPATIONAL HEALTH

Analysis of Career Stage, Gender, and Personality and Workplace Violence in a 20-Year Nationwide Cohort of Physicians in Norway

This cohort study examines the incidence of violence and threats of violence against physicians in Norway during a 20-year period.

JAMA Netw Open. 2021;4(6):e2114749. doi:10.1001/jamanetworkopen.2021.14749
Abstract Full Text pdf link PDF

ONCOLOGY

Assessment of 25-Year Survival of Women With Estrogen Receptor–Positive/ERBB2-Negative Breast Cancer Treated With and Without Tamoxifen Therapy: A Secondary Analysis of Data From the Stockholm Tamoxifen Randomized Clinical Trial

This secondary analysis of the Stockholm tamoxifen clinical trial examines the association of clinical breast cancer markers with 25-year survival and tamoxifen treatment benefit among postmenopausal women with lymph node–negative ER-positive/ERBB2-negative breast cancer.

JAMA Netw Open. 2021;4(6):e2114904. doi:10.1001/jamanetworkopen.2021.14904
Abstract Full Text pdf link PDF

OBSTETRICS AND GYNECOLOGY

Rates of Neuropsychiatric Disorders and Gestational Age at Birth in a Danish Population

This cohort study evaluates associations between 6 gestational age groups and rates of 9 major types and 8 subtypes of childhood-onset and adult-onset neuropsychiatric disorders using data from a Danish nationwide registry.

JAMA Netw Open. 2021;4(6):e2114913. doi:10.1001/jamanetworkopen.2021.14913
Abstract Full Text pdf link PDF

HEALTH POLICY

Association of Costs and Days at Home With Transfer Hospital in Home

This quality improvement study evaluates the outcomes of transfer hospital in home and its associations with costs and days at home by taking advantage of natural geographical limitations in the program’s service area.

JAMA Netw Open. 2021;4(6):e2114920. doi:10.1001/jamanetworkopen.2021.14920
Abstract Full Text pdf link PDF

CARDIOLOGY

Assessment of Coronary Artery Disease With Computed Tomography Angiography and Inflammatory and Immune Activation Biomarkers Among Adults With HIV Eligible for Primary Cardiovascular Prevention

This cohort study examines the prevalence of coronary artery disease (CAD) among adults with well-controlled HIV and low to moderate risk of atherosclerotic cardiovascular disease using computed tomography angiography and assessment of inflammation and immune activation biomarkers.

JAMA Netw Open. 2021;4(6):e2114923. doi:10.1001/jamanetworkopen.2021.14923
Abstract Full Text pdf link PDF

OBSTETRICS AND GYNECOLOGY

Joint Associations of Actual Age and Genetically Determined Age at Menarche With Risk of Mortality

This cohort study uses data from the UK Biobank to investigate joint associations of actual age and genetically determined age at menarche with risk of all-cause mortality.

JAMA Netw Open. 2021;4(6):e2115297. doi:10.1001/jamanetworkopen.2021.15297
Abstract Full Text pdf link PDF

CRITICAL CARE MEDICINE

Association of Annual Intensive Care Unit Sepsis Caseload With Hospital Mortality From Sepsis in the United Kingdom, 2010-2016

This cohort study assesses the association between the annual volume of patients with sepsis treated in intensive care units of UK hospitals and hospital mortality from sepsis between 2010 and 2016.

JAMA Netw Open. 2021;4(6):e2115305. doi:10.1001/jamanetworkopen.2021.15305
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Modeling Cervical Cancer Screening Strategies With Varying Levels of Human Papillomavirus Vaccination

This decision analytical model estimates the likely outcomes of different screening modalities and models the effect of growing uptake of the human papillomavirus (HPV) vaccine on the interpretation of screening results.

JAMA Netw Open. 2021;4(6):e2115321. doi:10.1001/jamanetworkopen.2021.15321
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

COVID-19 Case Investigation and Contact Tracing in the US, 2020

This cross-sectional study examines proportions of individuals with confirmed COVID-19 cases and their contacts reached by public health authorities and the amount of time needed to reach them and compares the risk of a positive test result between contacts and the general public.

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JAMA Netw Open. 2021;4(6):e2115850. doi:10.1001/jamanetworkopen.2021.15850
Abstract Full Text pdf link PDF CME & MOC

INFECTIOUS DISEASES

Assessment of Effectiveness of 1 Dose of BNT162b2 Vaccine for SARS-CoV-2 Infection 13 to 24 Days After Immunization

This comparative effectiveness study examines the effectiveness associated with 1 dose of the BNT162b2 COVID-19 vaccine in a real-world setting.

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JAMA Netw Open. 2021;4(6):e2115985. doi:10.1001/jamanetworkopen.2021.15985
Abstract Full Text pdf link PDF CME & MOC

PUBLIC HEALTH

Incidence of Multisystem Inflammatory Syndrome in Children Among US Persons Infected With SARS-CoV-2

This cohort study examines the incidence of multisystem inflammatory syndrome in children among persons in the US with SARS-CoV-2 infection.

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JAMA Netw Open. 2021;4(6):e2116420. doi:10.1001/jamanetworkopen.2021.16420
Abstract Full Text pdf link PDF CME & MOC

INFECTIOUS DISEASES

Assessment of a COVID-19 Control Plan on an Urban University Campus During a Second Wave of the Pandemic

This case series describes the use of a multifaceted COVID-19 control plan to reduce spread of SARS-CoV-2 at a large urban university during the second wave of the pandemic.

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JAMA Netw Open. 2021;4(6):e2116425. doi:10.1001/jamanetworkopen.2021.16425
Abstract Full Text pdf link PDF CME & MOC

PHARMACY AND CLINICAL PHARMACOLOGY

In Vitro Analysis of N-Nitrosodimethylamine (NDMA) Formation From Ranitidine Under Simulated Gastrointestinal Conditions

This study characterizes N-nitrosodimethylamine (NDMA) formation following the addition of ranitidine to simulated gastric fluid using combinations of fluid volume, pH levels, and nitrite concentrations, including physiologic levels.

JAMA Netw Open. 2021;4(6):e2118253. doi:10.1001/jamanetworkopen.2021.18253
Abstract Full Text pdf link PDF

CRITICAL CARE MEDICINE

Association of Positive Fluid Balance at Discharge After Sepsis Management With 30-Day Readmission

This cohort study evaluates whether positive fluid balance among non–critically ill patients with sepsis was associated with increased readmission risk, including readmission for heart failure.

JAMA Netw Open. 2021;4(6):e216105. doi:10.1001/jamanetworkopen.2021.6105
Abstract Full Text pdf link PDF

EMERGENCY MEDICINE

Comparison of Emergency Medical Dispatch Systems for Performance of Telecommunicator-Assisted Cardiopulmonary Resuscitation Among 9-1-1 Callers With Limited English Proficiency

This cohort study evaluates the prevalence of telecommunicator-assisted cardiopulmonary resuscitation among 9-1-1 callers with limited English language skills using 2 emergency medical services dispatch systems.

JAMA Netw Open. 2021;4(6):e216827. doi:10.1001/jamanetworkopen.2021.6827
Abstract Full Text pdf link PDF
open access Editorial

Enhancing Aging and Ending Ageism: JAMA Network Open Call for Papers

JAMA Netw Open. 2021;4(6):e2117621. doi:10.1001/jamanetworkopen.2021.17621
Abstract Full Text pdf link PDF

Equity and the JAMA Network

JAMA Netw Open. 2021;4(6):e2118381. doi:10.1001/jamanetworkopen.2021.18381
Abstract Full Text pdf link PDF

Structural Racism and JAMA Network Open

JAMA Netw Open. 2021;4(6):e2120269. doi:10.1001/jamanetworkopen.2021.20269
Abstract Full Text pdf link PDF
open access Invited Commentary

HEALTH POLICY

Nonrandomized Comparison of Adverse Events Following Facility- and Home-Infused Biologics Using Real-World Data

JAMA Netw Open. 2021;4(6):e2111156. doi:10.1001/jamanetworkopen.2021.11156
Abstract Full Text pdf link PDF

PEDIATRICS

COVID-19 in Children—Not Just Little Adults

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JAMA Netw Open. 2021;4(6):e2111441. doi:10.1001/jamanetworkopen.2021.11441
Abstract Full Text pdf link PDF CME & MOC

INFECTIOUS DISEASES

The Combined Effect of Vaccination and Nonpharmaceutical Public Health Interventions—Ending the COVID-19 Pandemic

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JAMA Netw Open. 2021;4(6):e2111675. doi:10.1001/jamanetworkopen.2021.11675
Abstract Full Text pdf link PDF CME & MOC

PEDIATRICS

Chilblains-like Nonischemic Eruption During the COVID-19 Pandemic—Distinct Features in Adolescents

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JAMA Netw Open. 2021;4(6):e2111676. doi:10.1001/jamanetworkopen.2021.11676
Abstract Full Text pdf link PDF CME & MOC

HEALTH POLICY

Hospitalization at Home for Patients With Acute Exacerbation of Chronic Disease—Further Evidence to Inform Practice

JAMA Netw Open. 2021;4(6):e2111680. doi:10.1001/jamanetworkopen.2021.11680
Abstract Full Text pdf link PDF

HEALTH POLICY

Unintended Consequences From the 2016 US Centers for Disease Control and Prevention Guideline for Prescribing Opioids—Accelerating Change in Postoperative Prescribing

JAMA Netw Open. 2021;4(6):e2111997. doi:10.1001/jamanetworkopen.2021.11997
Abstract Full Text pdf link PDF

HEALTH POLICY

Further Evidence Supporting the Use of Prophylactic Anticoagulation in Hospitalized Patients With COVID-19

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JAMA Netw Open. 2021;4(6):e2112403. doi:10.1001/jamanetworkopen.2021.12403
Abstract Full Text pdf link PDF CME & MOC

PUBLIC HEALTH

The Decline in e-Cigarette Use Among Youth in the United States—An Encouraging Trend but an Ongoing Public Health Challenge

JAMA Netw Open. 2021;4(6):e2112464. doi:10.1001/jamanetworkopen.2021.12464
Abstract Full Text pdf link PDF

PEDIATRICS

The Scarcity of Approved Pediatric High-Risk Medical Devices

JAMA Netw Open. 2021;4(6):e2112760. doi:10.1001/jamanetworkopen.2021.12760
Abstract Full Text pdf link PDF

CRITICAL CARE MEDICINE

Using Readmission Rates as a Quality Indicator in Sepsis—Addressing the Problem or Adding to It?

JAMA Netw Open. 2021;4(6):e2112873. doi:10.1001/jamanetworkopen.2021.12873
Abstract Full Text pdf link PDF

HEALTH INFORMATICS

On the Usage of Combined Data Structures to Study COVID-19 in Understudied Populations

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JAMA Netw Open. 2021;4(6):e2112874. doi:10.1001/jamanetworkopen.2021.12874
Abstract Full Text pdf link PDF CME & MOC

CARDIOLOGY

Daily Low-Dose Aspirin, Diabetes, and Age—Still Looking for a Balance

JAMA Netw Open. 2021;4(6):e2112875. doi:10.1001/jamanetworkopen.2021.12875
Abstract Full Text pdf link PDF

MEDICAL JOURNALS AND PUBLISHING

Implications of Sex Disparities in the h-Index for Academic Medicine

JAMA Netw Open. 2021;4(6):e2112877. doi:10.1001/jamanetworkopen.2021.12877
Abstract Full Text pdf link PDF

ONCOLOGY

Analysis of Survival Among Adults With Early-Onset Colorectal Cancer

JAMA Netw Open. 2021;4(6):e2112878. doi:10.1001/jamanetworkopen.2021.12878
Abstract Full Text pdf link PDF

HEALTH POLICY

Breaking Links in the Chain of Racial Disparities for COVID-19

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JAMA Netw Open. 2021;4(6):e2112879. doi:10.1001/jamanetworkopen.2021.12879
Abstract Full Text pdf link PDF CME & MOC

PEDIATRICS

Addressing the High Rates of Mortality in People With Intellectual Disability

JAMA Netw Open. 2021;4(6):e2113446. doi:10.1001/jamanetworkopen.2021.13446
Abstract Full Text pdf link PDF

CRITICAL CARE MEDICINE

Providing Family-Centered Intensive Care Unit Care Without Family Presence—Human Connection in the Time of COVID-19

JAMA Netw Open. 2021;4(6):e2113452. doi:10.1001/jamanetworkopen.2021.13452
Abstract Full Text pdf link PDF

PEDIATRICS

High Hopes for Very Preterm Infants in Neonatal Intensive Care Units in China

JAMA Netw Open. 2021;4(6):e2113649. doi:10.1001/jamanetworkopen.2021.13649
Abstract Full Text pdf link PDF

ONCOLOGY

Intensity-Modulated Radiation Therapy and Intensity-Modulated Proton Therapy—2 Effective Treatment Modalities for Nasopharyngeal Cancer

JAMA Netw Open. 2021;4(6):e2113650. doi:10.1001/jamanetworkopen.2021.13650
Abstract Full Text pdf link PDF

ONCOLOGY

Addressing Social Risk and Support as Adjuvants in Colorectal Cancer Treatment

JAMA Netw Open. 2021;4(6):e2113651. doi:10.1001/jamanetworkopen.2021.13651
Abstract Full Text pdf link PDF

GERIATRICS

Peer-to-Peer Support for Older Adults—What Do We Know and Where Do We Go?

JAMA Netw Open. 2021;4(6):e2113941. doi:10.1001/jamanetworkopen.2021.13941
Abstract Full Text pdf link PDF

SURGERY

Casting Data on Wrist Fracture Outcomes

JAMA Netw Open. 2021;4(6):e2114610. doi:10.1001/jamanetworkopen.2021.14610
Abstract Full Text pdf link PDF

GERIATRICS

Does Hearing Impairment Affect Physical Function?Current Evidence, Potential Mechanisms, and Future Research Directions for Healthy Aging

JAMA Netw Open. 2021;4(6):e2114782. doi:10.1001/jamanetworkopen.2021.14782
Abstract Full Text pdf link PDF

ORTHOPEDICS

Determining the Association of Preoperative Controlled Prescription Medication Use With Outcomes After Total Knee Arthroplasty

JAMA Netw Open. 2021;4(6):e2114785. doi:10.1001/jamanetworkopen.2021.14785
Abstract Full Text pdf link PDF

ONCOLOGY

Molecular Genetic Characterization of a Subset of Women With Early Breast Cancer Followed Up for 25 Years in the Stockholm Tamoxifen Clinical Trial

JAMA Netw Open. 2021;4(6):e2115227. doi:10.1001/jamanetworkopen.2021.15227
Abstract Full Text pdf link PDF

STATISTICS AND RESEARCH METHODS

Surgical Culture Shifts and Randomized Clinical Trials

JAMA Netw Open. 2021;4(6):e2115456. doi:10.1001/jamanetworkopen.2021.15456
Abstract Full Text pdf link PDF

EMERGENCY MEDICINE

Telecommunicator Cardiopulmonary Resuscitation—A Strategy Whose Time Has Come for the Other Pandemic

JAMA Netw Open. 2021;4(6):e217187. doi:10.1001/jamanetworkopen.2021.7187
Abstract Full Text pdf link PDF
open access Research Letter

STATISTICS AND RESEARCH METHODS

Reporting of Sociodemographic Variables in Randomized Clinical Trials, 2014-2020

This cross-sectional study assesses the frequency and thoroughness of reporting of sociodemographic variables in randomized clinical trials published in 5 high-impact health journals from January 2014 to July 2020.

JAMA Netw Open. 2021;4(6):e2110700. doi:10.1001/jamanetworkopen.2021.10700
Abstract Full Text pdf link PDF

MEDICAL EDUCATION

Association of Socioeconomic Status With Alpha Omega Alpha Honor Society Membership Among Medical Students

This cross-sectional study investigates the association between Alpha Omega Alpha (AΩA) honor society membership and medical student socioeconomic status.

JAMA Netw Open. 2021;4(6):e2110730. doi:10.1001/jamanetworkopen.2021.10730
Abstract Full Text pdf link PDF

HEALTH POLICY

Trends in the Use of Conventional and New Pharmaceuticals for Hemophilia Treatments Among Medicaid Enrollees, 2005-2020

This cohort study used Medicaid data to examine trends in the use of and spending for hemophilia pharmaceuticals from 2005 to 2020.

JAMA Netw Open. 2021;4(6):e2112044. doi:10.1001/jamanetworkopen.2021.12044
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Effect of Opt-In vs Opt-Out Framing on Enrollment in a COVID-19 Surveillance Testing Program: The COVID SAFE Randomized Clinical Trial

This randomized clinical trial examines the effect of an opt-out recruitment strategy vs a conventional opt-in strategy on enrollment and initial adherence to a COVID-19 surveillance testing program.

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JAMA Netw Open. 2021;4(6):e2112434. doi:10.1001/jamanetworkopen.2021.12434
Abstract Full Text pdf link PDF CME & MOC

HEALTH POLICY

Patient Characteristics and Subsequent Health Care Use by Location of SARS-CoV-2 Testing Initiation in a Safety-Net Health System

This cross-sectional study examines patterns in entry location for SARS-CoV-2 testing in a safety-net health system by patient demographic characteristics.

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JAMA Netw Open. 2021;4(6):e2112857. doi:10.1001/jamanetworkopen.2021.12857
Abstract Full Text pdf link PDF CME & MOC

PEDIATRICS

Medical Student Assessment of Pediatric Patient Pain as a Function of Perceived Child Gender

This survey study investigates whether the perceived gender of a child is associated with how medical students assess a pediatric patient’s pain displayed and pain experienced.

JAMA Netw Open. 2021;4(6):e2113010. doi:10.1001/jamanetworkopen.2021.13010
Abstract Full Text pdf link PDF

GERIATRICS

Estimation of Excess Mortality Rates Among US Assisted Living Residents During the COVID-19 Pandemic

This cohort study examines rates of mortality among US assisted living residents during the COVID-19 pandemic in comparison with the same period in 2019.

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JAMA Netw Open. 2021;4(6):e2113411. doi:10.1001/jamanetworkopen.2021.13411
Abstract Full Text pdf link PDF CME & MOC

HEALTH POLICY

International Medical Graduate Physician Deaths From COVID-19 in the United States

This case series study examines mortality rates due to COVID-19 among all physicians and international medical graduate physicians in the US.

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JAMA Netw Open. 2021;4(6):e2113418. doi:10.1001/jamanetworkopen.2021.13418
Abstract Full Text pdf link PDF CME & MOC

ONCOLOGY

Prevalence of Proton Pump Inhibitor Use Among Patients With Cancer

This cross-sectional study evaluates the prevalence of proton pump inhibitor use among patients with cancer at 4 French comprehensive cancer centers.

JAMA Netw Open. 2021;4(6):e2113739. doi:10.1001/jamanetworkopen.2021.13739
Abstract Full Text pdf link PDF

COMPLEMENTARY AND ALTERNATIVE MEDICINE

Evaluation of the Forced Inspiratory Suction and Swallow Tool to Stop Hiccups

This cross-sectional study evaluates the usefulness of the forced inspiratory suction and swallow tool for stopping hiccups in a group of volunteers who completed an online questionnaire..

JAMA Netw Open. 2021;4(6):e2113933. doi:10.1001/jamanetworkopen.2021.13933
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Assessment of Racial and Ethnic Disparities in Access to COVID-19 Vaccination Sites in Brooklyn, New York

This cross-sectional study examines the number and location of vaccination sites across 18 districts with varying racial and ethnic demographic characteristics in Brooklyn, New York.

JAMA Netw Open. 2021;4(6):e2113937. doi:10.1001/jamanetworkopen.2021.13937
Abstract Full Text pdf link PDF

HEALTH POLICY

Increases in Anti-infective Drug Prices, Subsequent Prescribing, and Outpatient Costs

This cross-sectional study examines the association of prices for drugs to treat hookworm and pinworm with prescribing and prescription-filling behaviors and total outpatient treatment costs.

JAMA Netw Open. 2021;4(6):e2113963. doi:10.1001/jamanetworkopen.2021.13963
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

SARS-CoV-2 Positivity and Mask Utilization Among Health Care Workers

This cohort study examines the association of mask use with COVID-19 transmission among health care workers in California.

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JAMA Netw Open. 2021;4(6):e2114325. doi:10.1001/jamanetworkopen.2021.14325
Abstract Full Text pdf link PDF CME & MOC

HEALTH POLICY

Changes in Hospitalizations at US Safety-Net Hospitals Following Medicaid Expansion

This cross-sectional study examines whether inpatient utilization among patients with lower socioeconomic status and among those who belong to racial/ethnic minority groups changed differentially in states that expanded Medicaid following the Patient Protection and Affordable Care Act (ACA).

JAMA Netw Open. 2021;4(6):e2114343. doi:10.1001/jamanetworkopen.2021.14343
Abstract Full Text pdf link PDF

HEALTH POLICY

Analysis of Medicare Advantage Plans’ Supplemental Benefits and Variation by County

This cross-sectional study examines the uptake of several newly allowable Medicare Advantage benefits in 2021 as well as geographic differences in benefit offerings between rural and urban areas, plan penetration, and social vulnerability.

JAMA Netw Open. 2021;4(6):e2114359. doi:10.1001/jamanetworkopen.2021.14359
Abstract Full Text pdf link PDF

HEALTH POLICY

Changes in Physician Work Hours and Patterns During the COVID-19 Pandemic

This study examines the hours worked and patterns of work activities before and during the COVID-19 pandemic among US physicians.

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JAMA Netw Open. 2021;4(6):e2114386. doi:10.1001/jamanetworkopen.2021.14386
Abstract Full Text pdf link PDF CME & MOC

PUBLIC HEALTH

Association of Mask Mandates and COVID-19 Case Rates, Hospitalizations, and Deaths in Kansas

This case-control study examines the association between counties that adopted state mask mandates in Kansas with COVID-19 cases, hospitalizations, and deaths.

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JAMA Netw Open. 2021;4(6):e2114514. doi:10.1001/jamanetworkopen.2021.14514
Abstract Full Text pdf link PDF CME & MOC

PUBLIC HEALTH

Association of the COVID-19 Pandemic With Estimated Life Expectancy by Race/Ethnicity in the United States, 2020

This cross-sectional study examines the association of the COVID-19 pandemic with estimated life expectancy by race/ethnicity in the US.

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JAMA Netw Open. 2021;4(6):e2114520. doi:10.1001/jamanetworkopen.2021.14520
Abstract Full Text pdf link PDF CME & MOC

INFECTIOUS DISEASES

Utility of Mass SARS-CoV-2 Testing of Asymptomatic Patients Before Ambulatory and Inpatient Preplanned Procedures Requiring Moderate Sedation or General Anesthesia

This quality improvement study describes the results of a mass preprocedure SARS-CoV-2 testing strategy during a period of high community transmission in Connecticut.

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JAMA Netw Open. 2021;4(6):e2114526. doi:10.1001/jamanetworkopen.2021.14526
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PUBLIC HEALTH

Comparison of COVID-19 Vaccine Approvals at the US Food and Drug Administration, European Medicines Agency, and Health Canada

This qualitative improvement study investigates COVID-19 vaccine approvals at 3 medicine regulatory agencies in the US, EU, and Canada, characterizing and contrasting regulatory review times, and analyzing the clinical evidence supporting authorization.

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JAMA Netw Open. 2021;4(6):e2114531. doi:10.1001/jamanetworkopen.2021.14531
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PEDIATRICS

Assessment of Mental Health of High School Students During Social Distancing and Remote Schooling During the COVID-19 Pandemic in Austria

This cross-sectional study assesses multiple aspects of mental health among high school students during the COVID-19 pandemic in Austria.

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JAMA Netw Open. 2021;4(6):e2114866. doi:10.1001/jamanetworkopen.2021.14866
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PUBLIC HEALTH

Effect of Targeted Messaging on Return to In-Person Visits During the COVID-19 Pandemic: A Randomized Clinical Trial

This randomized clinical trial assess whether targeted messaging could improve the return to in-person visits during the COVID-19 pandemic.

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JAMA Netw Open. 2021;4(6):e2115211. doi:10.1001/jamanetworkopen.2021.15211
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NUTRITION, OBESITY, AND EXERCISE

Effects of Wearing an N95 Respirator or Cloth Mask Among Adults at Peak Exercise: A Randomized Crossover Trial

This randomized crossover trial examines the effects of wearing a cloth mask or N95 respirator vs no mask at peak exercise among healthy, active adults.

JAMA Netw Open. 2021;4(6):e2115219. doi:10.1001/jamanetworkopen.2021.15219
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INFECTIOUS DISEASES

Clinical Outcomes for Patients With Anosmia 1 Year After COVID-19 Diagnosis

This cohort study examines the clinical course and prognosis of patients with COVID-19–related anosmia for 1 year after diagnosis.

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JAMA Netw Open. 2021;4(6):e2115352. doi:10.1001/jamanetworkopen.2021.15352
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MEDICAL JOURNALS AND PUBLISHING

Challenges in Identifying the Retracted Status of an Article

This cross-sectional study examines publisher websites and bibliographic databases to check their accordance with industry standards for documenting retracted publications.

JAMA Netw Open. 2021;4(6):e2115648. doi:10.1001/jamanetworkopen.2021.15648
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INFECTIOUS DISEASES

Trends in Respiratory Virus Infections During the COVID-19 Pandemic in Singapore, 2020

This cross-sectional study assessed the changes in respiratory virus prevalence in 2020 vs 2019 associated with the COVID-19 pandemic.

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JAMA Netw Open. 2021;4(6):e2115973. doi:10.1001/jamanetworkopen.2021.15973
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INFECTIOUS DISEASES

Incidence of SARS-CoV-2 Infection in Health Care Workers After a Single Dose of mRNA-1273 Vaccine

This cohort study of health care workers in a metropolitan Veterans Administration network examines the association of SARS-CoV-2 infection after receiving a single dose of mRNA-1273 vaccine compared with no vaccination.

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JAMA Netw Open. 2021;4(6):e2116416. doi:10.1001/jamanetworkopen.2021.16416
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PSYCHIATRY

Factors Associated With Self-reported Symptoms of Depression Among Adults With and Without a Previous COVID-19 Diagnosis

This survey study compares features of self-reported symptoms of major depression in adults with or without a prior COVID-19 diagnosis.

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JAMA Netw Open. 2021;4(6):e2116612. doi:10.1001/jamanetworkopen.2021.16612
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open access Correction

Errors in the Number of Patients and Results

JAMA Netw Open. 2021;4(6):e2115787. doi:10.1001/jamanetworkopen.2021.15787
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Error in Author’s Name

JAMA Netw Open. 2021;4(6):e2116800. doi:10.1001/jamanetworkopen.2021.16800
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Error in Abstract and Results

JAMA Netw Open. 2021;4(6):e2117001. doi:10.1001/jamanetworkopen.2021.17001
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Nonauthor Collaborator Names Added to a Supplement

JAMA Netw Open. 2021;4(6):e2117178. doi:10.1001/jamanetworkopen.2021.17178
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Nonauthor Collaborator Names Added to a Supplement

JAMA Netw Open. 2021;4(6):e2117240. doi:10.1001/jamanetworkopen.2021.17240
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Error in Figure 1

JAMA Netw Open. 2021;4(6):e2118052. doi:10.1001/jamanetworkopen.2021.18052
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Error in Author Name and Affilations

JAMA Netw Open. 2021;4(6):e2118300. doi:10.1001/jamanetworkopen.2021.18300
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Errors in x-Axis Labeling in Figure

JAMA Netw Open. 2021;4(6):e2118586. doi:10.1001/jamanetworkopen.2021.18586
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Error in Figure

JAMA Netw Open. 2021;4(6):e2118963. doi:10.1001/jamanetworkopen.2021.18963
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Typographic Error in Results

JAMA Netw Open. 2021;4(6):e2120001. doi:10.1001/jamanetworkopen.2021.20001
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open access JAMA Network Open Masthead

JAMA Network Open

JAMA Netw Open. 2021;4(6):e2115874. doi:10.1001/jamanetworkopen.2021.15874
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