COMPLEMENTARY AND ALTERNATIVE MEDICINE
Jinho Lee, KMD, PhD; Jae-Heung Cho, KMD, PhD; Koh-Woon Kim, KMD, PhD; et al.
This randomized clinical trial assesses whether Chuna manual therapy is more effective than usual care (electrotherapy and oral medication) for patients in Korea with chronic neck pain.
JAMA Netw Open. 2021;4(7):e2113757. doi:10.1001/jamanetworkopen.2021.13757
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Invited Commentary
East or West—Manual Therapy As a Viable Nonpharmacologic Option for Chronic Neck Pain
Julie M. Fritz, PT, PhD
JAMA Netw Open. 2021;4(7):e2114784. doi:10.1001/jamanetworkopen.2021.14784
PEDIATRICS
Ning Liu, PhD; Jing Xiao, PhD; Charul Gijavanekar, PhD; et al.
This cross-sectional study examines the utility of untargeted metabolomics as a primary screening tool for inborn errors of metabolism by comparing the diagnostic rate of clinical metabolomics with the recommended traditional metabolic screening approach.
JAMA Netw Open. 2021;4(7):e2114155. doi:10.1001/jamanetworkopen.2021.14155
GASTROENTEROLOGY AND HEPATOLOGY
Jianxian Lin, MD; Yajun Zhao, MD; Yanbing Zhou, MD; et al.
This cohort study examines differences in long-term survival and patterns of recurrence among patients with gastric neuroendocrine carcinoma, gastric mixed adenoneuroendocrine carcinoma, and gastric adenocarcinoma.
JAMA Netw Open. 2021;4(7):e2114180. doi:10.1001/jamanetworkopen.2021.14180
CARDIOLOGY
Utibe R. Essien, MD, MPH; Nadejda Kim, MA; Leslie R. M. Hausmann, PhD, MS; et al.
This cohort study uses data from the Veterans Health Administration system to compare rates of initiation of anticoagulant therapy by race/ethnicity.
JAMA Netw Open. 2021;4(7):e2114234. doi:10.1001/jamanetworkopen.2021.14234
CRITICAL CARE MEDICINE
Benjamine Sarton, MD; Pierre Jaquet, MD; Djida Belkacemi, MD; et al.
This cohort study investigates the association between early collected magnetic resonance imaging (MRI) data and functional outcomes 90 days after intensive care unit admission among adults with severe herpes simplex encephalitis.
JAMA Netw Open. 2021;4(7):e2114328. doi:10.1001/jamanetworkopen.2021.14328
GENETICS AND GENOMICS
Lilian Downie, MBBS; Jane Halliday, PhD; Sharon Lewis, PhD; et al.
This systematic review identifies what has been discovered following the reporting of the first genomic newborn screening pilot projects and summarizes key points for the design of these programs.
JAMA Netw Open. 2021;4(7):e2114336. doi:10.1001/jamanetworkopen.2021.14336
PEDIATRICS
Lisa Gaye Smithers, PhD; Joanne Hedges, MPH; Pedro Henrique Ribeiro Santiago, PhD; et al.
This secondary analysis reports the follow-up results of a dental care service provided to Indigenous Australian children and their caregivers who participated in the Baby Teeth Talk randomized clinical trial.
JAMA Netw Open. 2021;4(7):e2114348. doi:10.1001/jamanetworkopen.2021.14348
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Invited Commentary
Weighing the Unintended Consequences of Early Dental Care in Indigenous Australian Children
Prasanna K. Kapavarapu, MD; Vijay Srinivasan, MBBS, MD
JAMA Netw Open. 2021;4(7):e2114786. doi:10.1001/jamanetworkopen.2021.14786
NEUROLOGY
Rema Raman, PhD; Yakeel T. Quiroz, PhD; Oliver Langford, MS; et al.
This cross-sectional study of screening data from a preclinical Alzheimer disease trial assesses differences in recruitment strategies and trial eligibility among racial and ethnic groups.
JAMA Netw Open. 2021;4(7):e2114364. doi:10.1001/jamanetworkopen.2021.14364
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Invited Commentary
Inclusion of Underrepresented Groups in Preclinical Alzheimer Disease Trials—Opportunities Abound
Jennifer J. Manly, PhD; Andrea Gilmore-Bykovskyi, PhD, RN; Kacie D. Deters, PhD
JAMA Netw Open. 2021;4(7):e2114606. doi:10.1001/jamanetworkopen.2021.14606
CARDIOLOGY
Nicolas Isaza, MD; Paola Calvachi, MD, MSc, MBI; Inbar Raber, MD; et al.
This economic evaluation examined the cost-effectiveness of adding dapagliflozin to guideline-directed medical therapy for heart failure with reduced ejection fraction in a simulated cohort of patients with or without diabetes.
JAMA Netw Open. 2021;4(7):e2114501. doi:10.1001/jamanetworkopen.2021.14501
MEDICAL JOURNALS AND PUBLISHING
Paula Chatterjee, MD, MPH; Rachel M. Werner, MD, PhD
This cross-sectional study evaluates whether academic articles in high-impact medical journals written by men and women are cited differently.
JAMA Netw Open. 2021;4(7):e2114509. doi:10.1001/jamanetworkopen.2021.14509
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Invited Commentary
Gender Disparities in Journal Citations—Another Metric of Inequity in Academia
Helen R. Burstin, MD, MPH; Vineet M. Arora, MD, MAPP
JAMA Netw Open. 2021;4(7):e2114787. doi:10.1001/jamanetworkopen.2021.14787
ONCOLOGY
Shabbir M. H. Alibhai, MD, MSc; Henriette Breunis, CCRP; Gregory Feng, HBSc; et al.
This cohort study examines the association between cognitive function and chemotherapy in older men with metastatic castration-resistant prostate cancer.
JAMA Netw Open. 2021;4(7):e2114694. doi:10.1001/jamanetworkopen.2021.14694
PEDIATRICS
Scott W. Powers, PhD; Christopher S. Coffey, PhD; Leigh A. Chamberlin, RD, MEd; et al.
This survey study assesses migraine prevalence and disability of participants who completed the Childhood and Adolescent Migraine Prevention trial during 3 years of follow-up.
JAMA Netw Open. 2021;4(7):e2114712. doi:10.1001/jamanetworkopen.2021.14712
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Invited Commentary
Implications of 3-Year Follow-up Data From the Childhood and Adolescent Migraine Prevention Medication Trial
Sinifunanya E. Nwaobi, MD, PhD; Joshua Kamins, MD
JAMA Netw Open. 2021;4(7):e2114788. doi:10.1001/jamanetworkopen.2021.14788
HEALTH INFORMATICS
Qianyu Yuan, PhD; Tianrun Cai, MD; Chuan Hong, PhD; et al.
This cohort study investigates the performance of a machine learning algorithm used to extract a cohort of patients with lung cancer from electronic health records and estimate overall survival.
JAMA Netw Open. 2021;4(7):e2114723. doi:10.1001/jamanetworkopen.2021.14723
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Invited Commentary
Progress in the Application of Machine Learning Algorithms to Cancer Research and Care
Neal J. Meropol, MD; Janet Donegan, BSN, MA; Alexander S. Rich, PhD
JAMA Netw Open. 2021;4(7):e2116063. doi:10.1001/jamanetworkopen.2021.16063
INFECTIOUS DISEASES
Michael E. Ohl, MD, MSPH; Donald R. Miller, ScD; Brian C. Lund, PharmD; et al.
This cohort study assesses the association of remdesivir treatment with 30-day survival and length of hospital stay among US veterans hospitalized with COVID-19 between May and October 2020.
has active quiz
JAMA Netw Open. 2021;4(7):e2114741. doi:10.1001/jamanetworkopen.2021.14741
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Invited Commentary
Remdesivir Use and Hospital Length of Stay—The Paradox of a Clinical Trial vs Real-Life Use
Gio J. Baracco, MD
JAMA Netw Open. 2021;4(7):e2116057. doi:10.1001/jamanetworkopen.2021.16057
ONCOLOGY
Geoffrey Y. Ku, MD; Yelena Kemel, MS; Steve B. Maron, MD; et al.
This genetic association study examines the prevalence of likely pathogenic or pathogenic germline alterations among patients with esophagogastric cancer and assesses associations between germline variant prevalence and demographic and clinicopathologic features.
JAMA Netw Open. 2021;4(7):e2114753. doi:10.1001/jamanetworkopen.2021.14753
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Invited Commentary
Expanding Germline Testing to All Patients With Esophagogastric Cancers—Easy to Do, Harder to Justify
Thomas L. Holden, MD; Catherine Neumann, MS, LCGC; Michael J. Hall, MD, MS
JAMA Netw Open. 2021;4(7):e2114789. doi:10.1001/jamanetworkopen.2021.14789
SURGERY
Noyan Gokce, MD; Shakun Karki, PhD; Alyssa Dobyns, MS; et al.
This cohort study identifies variables associated with vascular remodeling after bariatric surgery and examines how sex, race, and metabolic status are associated with microvascular and macrovascular outcomes.
JAMA Netw Open. 2021;4(7):e2115267. doi:10.1001/jamanetworkopen.2021.15267
ONCOLOGY
Amar U. Kishan, MD; R. Jeffrey Karnes, MD; Tahmineh Romero, MS; et al.
This cohort study assesses prostate cancer–specific mortality and distant metastasis outcomes among men with high-risk prostate cancer treated with radical prostatectomy or external beam radiotherapy with or without brachytherapy boost.
JAMA Netw Open. 2021;4(7):e2115312. doi:10.1001/jamanetworkopen.2021.15312
MEDICAL EDUCATION
Bradley M. Gray, PhD; Jonathan L. Vandergrift, MS; Weifeng Weng, PhD; et al.
This cross-sectional study compares the association of clinical knowledge with opioid prescribing from 2009 to 2011 when prescribing peaked nationally with 2015 to 2017 when guidelines shifted away from opioid prescribing.
JAMA Netw Open. 2021;4(7):e2115328. doi:10.1001/jamanetworkopen.2021.15328
HEALTH INFORMATICS
Adam Rule, PhD; Steven Bedrick, PhD; Michael F. Chiang, MD; et al.
This cross-sectional study examines whether author experience and method of note entry are associated with the length and redundancy of progress notes among multiple medical specialties.
JAMA Netw Open. 2021;4(7):e2115334. doi:10.1001/jamanetworkopen.2021.15334
HEALTH POLICY
Chima D. Ndumele, PhD; Michael S. Cohen, PhD; Muriel Solberg, AB; et al.
This cross-sectional study uses data from the Centers for Medicare & Medicaid Services to assess whether higher-performing hospitals are more likely to advertise their services directly to consumers.
JAMA Netw Open. 2021;4(7):e2115342. doi:10.1001/jamanetworkopen.2021.15342
PUBLIC HEALTH
Linh Tran, BA; Roger Feldman, PhD; Thomas Riley III, MD, MS; et al.
This cohort study uses data from Medicare beneficiaries to assess the association between Project ECHO (Extension for Community Healthcare Outcomes) and increased use of hepatitis C virus treatment, particularly in resource-limited areas.
JAMA Netw Open. 2021;4(7):e2115523. doi:10.1001/jamanetworkopen.2021.15523
OBSTETRICS AND GYNECOLOGY
Kirsten M. J. Thompson, MPH; Hugh J. W. Sturrock, PhD; Diana Greene Foster, PhD; et al.
This cross-sectional geographic study examines the association between travel distance to the nearest abortion care facility and abortion rate and models the effect of reduced travel distance among US female residents of reproduction age.
JAMA Netw Open. 2021;4(7):e2115530. doi:10.1001/jamanetworkopen.2021.15530
MEDICAL EDUCATION
Deborah J. Gorth, MD, PhD; Rogan G. Magee, MD, PhD; Sarah E. Rosenberg, MD; et al.
This cohort study assesses whether there are gender differences in objective or subjective evaluations of third-year medical students participating in an internal medicine clerkship.
JAMA Netw Open. 2021;4(7):e2115661. doi:10.1001/jamanetworkopen.2021.15661
ONCOLOGY
Rahul Banerjee, MD; Vinay Prasad, MD, MPH
This systematic review analyzes the characteristics of registered chimeric antigen receptor–related trials with dual focuses on trial methods and intent.
JAMA Netw Open. 2021;4(7):e2115668. doi:10.1001/jamanetworkopen.2021.15668
ONCOLOGY
Zachary A. K. Frosch, MD; Nicholas Illenberger, MS; Nandita Mitra, PhD; et al.
This cross-sectional study uses data from the National Cancer Database to investigate trends in patient volume by hospital type and the association of patient volume with time to treatment initiation for patients with cancer by hospital type.
JAMA Netw Open. 2021;4(7):e2115675. doi:10.1001/jamanetworkopen.2021.15675
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Invited Commentary
Can the Health Care System Manage Increased Workloads From Expanded Access to Cancer Treatment?
Fabian McCartney Johnston, MD, MHS; Thomas J. Smith, MD
JAMA Netw Open. 2021;4(7):e2115763. doi:10.1001/jamanetworkopen.2021.15763
PSYCHIATRY
Donna A. Ruch, PhD; Kendra M. Heck, MPH; Arielle H. Sheftall, PhD; et al.
This qualitative study assesses characteristics and precipitating circumstances of suicide among children aged 5 to 11 years in the US.
JAMA Netw Open. 2021;4(7):e2115683. doi:10.1001/jamanetworkopen.2021.15683
SUBSTANCE USE AND ADDICTION
Tyler N. A. Winkelman, MD, MSc; Becky R. Ford, PhD; Shira Dunsiger, PhD; et al.
This pilot randomized clinical trial examines the acceptability, feasibility, and preliminary clinical outcomes of a smoking cessation intervention for individuals who are incarcerated in a pretrial, urban jail.
JAMA Netw Open. 2021;4(7):e2115687. doi:10.1001/jamanetworkopen.2021.15687
INFECTIOUS DISEASES
Piero Poletti, PhD; Marcello Tirani, MD; Danilo Cereda, MD; et al.
This cross-sectional study investigates seroprevalence and odds of SARS-CoV-2 infection among health care workers in different professional categories and operational units in Italy.
has active quiz
JAMA Netw Open. 2021;4(7):e2115699. doi:10.1001/jamanetworkopen.2021.15699
PSYCHIATRY
Lisa A. Brenner, PhD; Lisa M. Betthauser, PhD; Molly Penzenik, MPH; et al.
This diagnostic study develops and validates a tool for use in diagnostic screening of US military veterans for posttraumatic stress disorder.
JAMA Netw Open. 2021;4(7):e2115707. doi:10.1001/jamanetworkopen.2021.15707
PUBLIC HEALTH
Yu-Tien Hsu, MD, MPH; Ya-Wen Chen, MD, MPH; David C. Chang, PhD, MPH, MBA; et al.
This cross-sectional study uses data from the New York Statewide Planning and Research Cooperative System to assess the annual incidence of hospitalization for nonfatal firearm-related injuries in New York overall and by sex, race/ethnicity, county of residence, and calendar year from 2005 to 2016.
JAMA Netw Open. 2021;4(7):e2115713. doi:10.1001/jamanetworkopen.2021.15713
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Invited Commentary
Using State Hospitalization Databases to Improve Firearm Injury Data—A Step in the Right Direction
Ashley B. Hink, MD, MPH
JAMA Netw Open. 2021;4(7):e2115807. doi:10.1001/jamanetworkopen.2021.15807
HEALTH POLICY
José Luis Sandoval, MD, PhD; Dusan Petrovic, PhD; Idris Guessous, MD, PhD; et al.
This cross-sectional study examines the association between insurance plan deductibles and forgoing of health care, with consideration of socioeconomic factors, in a consumer-driven health care system with universal coverage in Switzerland.
JAMA Netw Open. 2021;4(7):e2115722. doi:10.1001/jamanetworkopen.2021.15722
NEUROLOGY
David Haupenthal, MD; Joji B. Kuramatsu, MD; Bastian Volbers, MD; et al.
This cohort study examines the association of intracerebral hemorrhage and secondary injury with disability-adjusted life years.
JAMA Netw Open. 2021;4(7):e2115859. doi:10.1001/jamanetworkopen.2021.15859
HEMATOLOGY
Sijian Yu, MD; Zhiping Fan, MD; Liping Ma, MD; et al.
This registry-based cohort study investigates postremission treatment choices and outcomes based on dynamic measurable residual disease in adults with intermediate-risk acute myeloid leukemia (AML).
JAMA Netw Open. 2021;4(7):e2115991. doi:10.1001/jamanetworkopen.2021.15991
PEDIATRICS
Mihai Puia-Dumitrescu, MD, MPH; Bryan A. Comstock, MS; Sijia Li, BS; et al.
This cohort study describes the use of opioids and benzodiazepines in extremely preterm infants during neonatal intensive care unit hospitalization and explores these drugs’ association with neurodevelopmental outcomes at 2 years’ corrected age.
JAMA Netw Open. 2021;4(7):e2115998. doi:10.1001/jamanetworkopen.2021.15998
CARDIOLOGY
Celia C. Kamath, PhD; Rachel Giblon, MS; Marlene Kunneman, PhD; et al.
This cohort study, a secondary analysis of a randomized clinical trial, assesses factors contributing to cost conversations about care plans between clinicians and patients with atrial fibrillation.
JAMA Netw Open. 2021;4(7):e2116009. doi:10.1001/jamanetworkopen.2021.16009
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Editorial
Cost Conversations About Atrial Fibrillation Care—Who Is Talking the Talk?
Ishani Ganguli, MD, MPH; Nitya Thakore, BA
JAMA Netw Open. 2021;4(7):e2116670. doi:10.1001/jamanetworkopen.2021.16670
HEALTH POLICY
Molly Grassini, MD; Sophie Terp, MD, MPH; Briah Fischer, MD, MPH; et al.
This case series described the characteristics of deaths among individuals detained in US Immigration and Customs Enforcement (ICE) facilities from 2011 to 2018.
JAMA Netw Open. 2021;4(7):e2116019. doi:10.1001/jamanetworkopen.2021.16019
PUBLIC HEALTH
W. Benjamin Goodman, PhD; Kenneth A. Dodge, PhD; Yu Bai, PhD; et al.
This randomized clinical trial examines the effect of randomization to the Family Connects program on child maltreatment investigations and emergency medical care through 5 years of age.
JAMA Netw Open. 2021;4(7):e2116024. doi:10.1001/jamanetworkopen.2021.16024
PUBLIC HEALTH
Ingrid Eshun-Wilson, MBChB, MSc; Aaloke Mody, MD, MSc; Virginia McKay, PhD; et al.
This survey study evaluates public preferences for social distancing strategies weighed against the hypothetical risk of acquiring COVID-19 and anticipated income loss.
has active quiz
JAMA Netw Open. 2021;4(7):e2116113. doi:10.1001/jamanetworkopen.2021.16113
ONCOLOGY
Eduardo R. Núñez, MD; Tanner J. Caverly, MD, MPH; Sanqian Zhang, MS; et al.
This cohort study examines adherence to follow-up testing recommendations after lung cancer screening among US veterans.
JAMA Netw Open. 2021;4(7):e2116233. doi:10.1001/jamanetworkopen.2021.16233
ONCOLOGY
Jian-Xian Lin, MD, PhD; Yan-Chang Xu, MD, PhD; Wei Lin, MD, PhD; et al.
This nonrandomized controlled trial evaluates the resection rate, responses, survival, adverse events, and surgical outcomes associated with a drug regimen for locally advanced gastric cancer.
JAMA Netw Open. 2021;4(7):e2116240. doi:10.1001/jamanetworkopen.2021.16240
ONCOLOGY
Skye Balyasny; Sang Mee Lee, PhD; Ami V. Desai, MD; et al.
This cohort study investigates whether participation in a clinical trial is associated with improved survival among children with neuroblastoma and investigates potential recruitment bias of patients in clinical trials.
JAMA Netw Open. 2021;4(7):e2116248. doi:10.1001/jamanetworkopen.2021.16248
NUTRITION, OBESITY, AND EXERCISE
Anish K. Agarwal, MD, MPH, MS; Kimberly J. Waddell, PhD; Dylan S. Small, PhD; et al.
This randomized clinical trial examines the effectiveness of gamification with social support, with and without a loss-framed financial incentive, to increase physical activity among veterans with overweight and obesity.
JAMA Netw Open. 2021;4(7):e2116256. doi:10.1001/jamanetworkopen.2021.16256
HEALTH POLICY
Juan F. Javier-DesLoges, MD, MS; Julia Yuan, BS; Shady Soliman, MS; et al.
This cohort study tests the hypothesis that implementation of the Patient Protection and Affordable Care Act may be associated with increased access to care through expansion of insurance, which may vary based on income, among patients with renal cell carcinoma.
JAMA Netw Open. 2021;4(7):e2116267. doi:10.1001/jamanetworkopen.2021.16267
ONCOLOGY
Kaustuv Bhattacharya, PhD; John P. Bentley, PhD; Sujith Ramachandran, PhD; et al.
This cohort study examines the costs associated with the prediagnosis, initial care, continuing care, and terminal phases of multiple myeloma in older adults.
JAMA Netw Open. 2021;4(7):e2116357. doi:10.1001/jamanetworkopen.2021.16357
PEDIATRICS
Chardée A. Galán, PhD; Lynissa R. Stokes, PhD; Nicholas Szoko, MD; et al.
This cross-sectional survey study of high school students at 13 public high schools in a large US city examines associations of bullying based on racial/ethnic, gender, and other marginalized identities with outcomes for health, mental health, and violence.
JAMA Netw Open. 2021;4(7):e2116364. doi:10.1001/jamanetworkopen.2021.16364
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Invited Commentary
Exploration of Identity-Based Bullying by Race/Ethnicity and Other Marginalized Identities Among Adolescents
Sandra Graham, PhD
JAMA Netw Open. 2021;4(7):e2117827. doi:10.1001/jamanetworkopen.2021.17827
NUTRITION, OBESITY, AND EXERCISE
Alexander Hodkinson, PhD; Evangelos Kontopantelis, PhD; Charles Adeniji, MD; et al.
This systematic review an meta-analysis assesses the association of interventions using wearable physical activity tracking devices with physical activity levels and other health outcomes among adults with cardiometabolic conditions.
JAMA Netw Open. 2021;4(7):e2116382. doi:10.1001/jamanetworkopen.2021.16382
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Invited Commentary
Integrated Physical Activity Campaign With Wearable Devices and Practitioner Consultation
Paul Ritvo, PhD; Megan Kirk, PhD; Meysam Pirbaglou, PhD
JAMA Netw Open. 2021;4(7):e2116671. doi:10.1001/jamanetworkopen.2021.16671
ONCOLOGY
Edoardo Francini, MD, PhD; Francesco Montagnani, MD, MS; Pier Vitale Nuzzo, MD, PhD; et al.
This cohort study examines whether the addition of bone resorption inhibitors is associated with improvements in overall survival and skeletal-related events among patients with metastatic castration-resistant prostate cancer receiving abiraterone acetate with prednisone as first-line therapy.
JAMA Netw Open. 2021;4(7):e2116536. doi:10.1001/jamanetworkopen.2021.16536
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Invited Commentary
Use of Bone Resorption Inhibitors in Metastatic Castration-Resistant Prostate Cancer—20 Years Later, and the Answer Is Still Yes
Samuel U. Takvorian, MD, MSHP; Naomi B. Haas, MD
JAMA Netw Open. 2021;4(7):e2117159. doi:10.1001/jamanetworkopen.2021.17159
PUBLIC HEALTH
Tracy L. Nelson, MPH, PhD; Bailey K. Fosdick, PhD; Laurie M. Biela, BS; et al.
This cross-sectional study evaluates self-reported behaviors and cases of SARS-CoV-2 infection among essential in-person employees during the first 6 months of the COVID-19 pandemic at a US institution of higher education.
has active quiz
JAMA Netw Open. 2021;4(7):e2116543. doi:10.1001/jamanetworkopen.2021.16543
SUBSTANCE USE AND ADDICTION
Natasha Y. Sheikhan, MPH; Ashlyn M. Pinto, MD, MSc; Dominik A. Nowak, MD, MHSc; et al.
This cross-sectional study evaluates compliance among licensed firms in Canada to the Cannabis Act and analyzes trends among violations regarding promotional material.
JAMA Netw Open. 2021;4(7):e2116551. doi:10.1001/jamanetworkopen.2021.16551
INFECTIOUS DISEASES
Lona Mody, MD, MSc; Kyle J. Gontjes, MPH; Marco Cassone, MD, PhD; et al.
This cluster randomized clinical trial examines the effectiveness of a multicomponent infection prevention intervention for multidrug resistant organisms in nursing homes.
JAMA Netw Open. 2021;4(7):e2116555. doi:10.1001/jamanetworkopen.2021.16555
CARDIOLOGY
Natalie Glaser, MD, PhD; Michael Persson, MD; Magnus Dalén, MD, PhD; et al.
This cohort study investigates the association of long-term adverse clinical outcomes, including mortality, with permanent pacemaker implantation after surgical aortic valve replacement.
JAMA Netw Open. 2021;4(7):e2116564. doi:10.1001/jamanetworkopen.2021.16564
NEPHROLOGY
Shuchi Anand, MD; Maria Montez-Rath, PhD; Jialin Han, MS; et al.
This cross-sectional study uses data from a dialysis organization in the US to assess the seroprevalence of SARS-CoV-2 antibodies among patients receiving dialysis and to estimate the seroprevalence among the adult population 1 year into the COVID-19 pandemic.
has active quiz
JAMA Netw Open. 2021;4(7):e2116572. doi:10.1001/jamanetworkopen.2021.16572
PEDIATRICS
Izzuddin M. Aris, PhD; Pi-I D. Lin, ScD; Sheryl L. Rifas-Shiman, MPH; et al.
This cohort study uses data from the National Patient-Centered Clinical Research Network (PCORnet) Antibiotics Childhood Growth Study to examine the association of antibiotic use during the first 4 years of life and body mass index trajectory milestones during childhood in a large cohort of children.
JAMA Netw Open. 2021;4(7):e2116581. doi:10.1001/jamanetworkopen.2021.16581
PSYCHIATRY
Ida Rönnqvist, MD; Fredrik K. Nilsson, MD; Axel Nordenskjöld, MD, PhD
This cohort study uses data from the Swedish National Quality Register to investigate the association of electroconvulsive therapy with suicide risk in hospitalized patients diagnosed with major depressive disorder.
JAMA Netw Open. 2021;4(7):e2116589. doi:10.1001/jamanetworkopen.2021.16589
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Invited Commentary
Benefits of Electroconvulsive Therapy for Patients With Major Depressive Disorder
Bradley N. Gaynes, MD, MPH
JAMA Netw Open. 2021;4(7):e2116674. doi:10.1001/jamanetworkopen.2021.16674
DIABETES AND ENDOCRINOLOGY
Kevin M. Pantalone, DO; B. Gabriel Smolarz, MD; Abhilasha Ramasamy, MSc, MS; et al.
This randomized clinical trial examines whether access to antiobesity medication combined with participation in a real-world, employer-based weight management program achieves clinically meaningful and superior weight loss compared with participation in the weight loss program alone among adults with obesity.
JAMA Netw Open. 2021;4(7):e2116595. doi:10.1001/jamanetworkopen.2021.16595
NEUROLOGY
Ruchira M. Jha, MD, MSc; Benjamin E. Zusman, MD, MSc; Ava M. Puccio, PhD; et al.
This genetic association study examines the association of DNA sequence variability in ABCC8 and TRPM4 with intraparenchymal hemorrhage progression in patients with severe traumatic brain injury (TBI).
JAMA Netw Open. 2021;4(7):e2116839. doi:10.1001/jamanetworkopen.2021.16839
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Invited Commentary
Finding a Place for Candidate Gene Studies in a Genome-Wide Association Study World
David K. Menon, MD, PhD; Jonathan Rosand, MD, MSc
JAMA Netw Open. 2021;4(7):e2118594. doi:10.1001/jamanetworkopen.2021.18594
PSYCHIATRY
Tatum M. Cummins, MSc; Oliver English, MSc; Helen Minnis, PhD; et al.
This cross-sectional study assesses somatosensory function in adolescents and compares their somatosensory profiles with community control participants to investigate associations with the incidence and frequency of self-harm.
JAMA Netw Open. 2021;4(7):e2116853. doi:10.1001/jamanetworkopen.2021.16853
SUBSTANCE USE AND ADDICTION
Jason E. Goldstick, PhD; Gery P. Guy, PhD; Jan L. Losby, PhD; et al.
This cohort examines trends in opioid prescribing for patients who were opioid naive before and after the release of prescribing guidelines by the Centers for Disease Control and Prevention (CDC).
JAMA Netw Open. 2021;4(7):e2116860. doi:10.1001/jamanetworkopen.2021.16860
HEALTH INFORMATICS
Tellen D. Bennett, MD; Richard A. Moffitt, PhD; Janos G. Hajagos, PhD; et al.
This cohort study evaluates COVID-19 severity and factors associated with severity over time and assesses the use of machine learning to predict clinical severity.
has active quiz
JAMA Netw Open. 2021;4(7):e2116901. doi:10.1001/jamanetworkopen.2021.16901
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Invited Commentary
Aggregating Electronic Health Record Data for COVID-19 Research—Caveat Emptor
Jeffrey S. Brown, PhD; Lisa Bastarache, MS; Mark G. Weiner, MD
JAMA Netw Open. 2021;4(7):e2117175. doi:10.1001/jamanetworkopen.2021.17175
PHARMACY AND CLINICAL PHARMACOLOGY
William Galanter, MD, PhD; Tewodros Eguale, MD, PhD; Walid Gellad, MD; et al.
This cohort study examines how primary care physicians’ personal formularies differ at 4 institutions; evaluates associations between personal formularies and patient, physician, and practice site characteristics; and examines the variability of the top 200 core drugs prescribed at the 4 sites.
JAMA Netw Open. 2021;4(7):e2117038. doi:10.1001/jamanetworkopen.2021.17038
PUBLIC HEALTH
Carol L. Galletly, JD, PhD; Julia Lechuga, PhD; Julia B. Dickson-Gomez, PhD; et al.
This cross-sectional survey study examines the proportion of adult Latinx immigrants in the US who endorse statements about the immigration ramifications of engaging in COVID-19–related testing, treatment, and contact tracing.
has active quiz
JAMA Netw Open. 2021;4(7):e2117049. doi:10.1001/jamanetworkopen.2021.17049
ETHICS
Jenny Park; Somnath Saha, MD, MPH; Brant Chee, PhD; et al.
This qualitative study examines both negative and positive attitudes expressed by physicians about patients in electronic medical records.
JAMA Netw Open. 2021;4(7):e2117052. doi:10.1001/jamanetworkopen.2021.17052
PUBLIC HEALTH
Lijun Wang, MPH; Jianjiu Chen, PhD; Lok Tung Leung, PhD; et al.
This cross-sectional study investigates associations of persistent respiratory symptoms with heated tobacco product use, cigarette use, and dual use among youth in Hong Kong.
JAMA Netw Open. 2021;4(7):e2117055. doi:10.1001/jamanetworkopen.2021.17055
PUBLIC HEALTH
Yuki Yoshikawa, MD, MPH; Ichiro Kawachi, MD, PhD
This cross-sectional study examines the association of socioeconomic characteristics with COVID-19 incidence and mortality in Japanese prefectures.
has active quiz
JAMA Netw Open. 2021;4(7):e2117060. doi:10.1001/jamanetworkopen.2021.17060
PUBLIC HEALTH
Eugenia C. South, MD; John MacDonald, PhD; Vincent Reina, PhD
This cross-sectional study examines the association between a housing renewal grant program implemented in socially disadvantaged, racially segregated communities in Philadelphia, Pennsylvania, and neighborhood crime.
JAMA Netw Open. 2021;4(7):e2117067. doi:10.1001/jamanetworkopen.2021.17067
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Invited Commentary
Housing Repair and Crime—Investment at a Small Scale for a Potential Big Impact
Marie Skubak Tillyer, PhD; Rebecca J. Walter, PhD; Arthur Acolin, PhD
JAMA Netw Open. 2021;4(7):e2117624. doi:10.1001/jamanetworkopen.2021.17624
PUBLIC HEALTH
Manuel E. Jimenez, MD, MS; Zorimar Rivera-Núñez, PhD, MS; Benjamin F. Crabtree, PhD; et al.
This qualitative study explores the experiences of Black and Latinx communities during the pandemic to better understand their perspectives on COVID-19 mitigation behaviors (eg, mask wearing), testing, and vaccines.
has active quiz
JAMA Netw Open. 2021;4(7):e2117074. doi:10.1001/jamanetworkopen.2021.17074
INFECTIOUS DISEASES
Carlos Torres, MD; Lucy Ogbu-Nwobodo, MD, MS, MAS; Marcella Alsan, MD, MPH, PhD; et al.
This randomized clinical trial evaluates whether messages delivered by physicians improve COVID-19 knowledge and preventive behaviors and assesses the differential effectiveness of messages tailored to the Black community.
has active quiz
JAMA Netw Open. 2021;4(7):e2117115. doi:10.1001/jamanetworkopen.2021.17115
SUBSTANCE USE AND ADDICTION
Andrew A. Herring, MD; Aidan A. Vosooghi, MS; Joshua Luftig, PA; et al.
This case series examines the safety and tolerability of high-dose (>12 mg) buprenorphine induction in the emergency department (ED) for treatment of opioid use disorder.
JAMA Netw Open. 2021;4(7):e2117128. doi:10.1001/jamanetworkopen.2021.17128
HEALTH INFORMATICS
Ethan Andrew Chi; Gordon Chi; Cheuk To Tsui, BS; et al.
This prognostic study evaluates the utility of and potential time savings, accuracy, and user experience associated with an artificial intelligence–optimized electronic health record tested by 12 gastroenterologists.
JAMA Netw Open. 2021;4(7):e2117391. doi:10.1001/jamanetworkopen.2021.17391
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Invited Commentary
Using Artificial Intelligence to Make Use of Electronic Health Records Less Painful—Fighting Fire With Fire
Richard J. Baron, MD
JAMA Netw Open. 2021;4(7):e2118298. doi:10.1001/jamanetworkopen.2021.18298
NEUROLOGY
Irene L. Katzan, MD; Andrew Schuster, BA; Lynn Daboul, BS; et al.
This cohort study investigates changes in patient-reported global health as measured before vs after transient ischemic attack.
JAMA Netw Open. 2021;4(7):e2117403. doi:10.1001/jamanetworkopen.2021.17403
OBSTETRICS AND GYNECOLOGY
Fuzhen Song, MD; Yuanyuan Chen, MSc; Lei Chen, MSc; et al.
This cohort study investigates the association between maternal serum total bile acid concentrations during pregnancy and the risk of intrauterine growth restriction.
JAMA Netw Open. 2021;4(7):e2117409. doi:10.1001/jamanetworkopen.2021.17409
OPHTHALMOLOGY
Varshini Varadaraj, MD, MPH; Beatriz Munoz, MS; Jennifer A. Deal, PhD; et al.
This cohort study examines the association between visual and cognitive impairments across multiple cognitive domains using multiple measures of vision.
JAMA Netw Open. 2021;4(7):e2117416. doi:10.1001/jamanetworkopen.2021.17416
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Invited Commentary
Beyond Visual Acuity—A Comprehensive Assessment of Vision and Cognition in Older Adults With Visual Impairment
Preeti Gupta, PhD; Tai Anh Vu, BSc; Ecosse L. Lamoureux, PhD
JAMA Netw Open. 2021;4(7):e2119033. doi:10.1001/jamanetworkopen.2021.19033
SURGERY
Marko Simunovic, MD; David Robert Urbach, MD; Christine Fahim, PhD; et al.
This quality improvement study uses administrative patient data from 14 regions in Ontario, Canada, to evaluate the association of sustained, iterative, integrated knowledge translation interventions for rectal cancer surgery directed at all surgeons in a geographic region with process and outcome measures among patients undergoing rectal cancer surgery.
JAMA Netw Open. 2021;4(7):e2117536. doi:10.1001/jamanetworkopen.2021.17536
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Invited Commentary
High-Intensity vs Low-Intensity Knowledge Translation and Performance Metrics in Patients With Rectal Cancer
Steven D. Wexner, MD
JAMA Netw Open. 2021;4(7):e2119393. doi:10.1001/jamanetworkopen.2021.19393
PEDIATRICS
Suzanne Schuh, MD; Stephen B. Freedman, MDCM, MSc; Roger Zemek, MD; et al.
This cohort study assesses the association between intravenous magnesium therapy administered in the emergency department and subsequent hospitalization among pediatric patients with refractory acute asthma in Canada.
JAMA Netw Open. 2021;4(7):e2117542. doi:10.1001/jamanetworkopen.2021.17542
ONCOLOGY
Kenneth L. Kehl, MD, MPH; Gregory J. Riely, MD, PhD; Eva M. Lepisto, MA, MSc; et al.
This cohort study measures associations between candidate surrogate end points and overall survival in a multi-institutional clinicogenomic data set of patients with non–small cell lung cancer (NSCLC) or colorectal cancer.
JAMA Netw Open. 2021;4(7):e2117547. doi:10.1001/jamanetworkopen.2021.17547
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Invited Commentary
Assessing Clinical Outcomes in a Data-Rich World—A Reality Check on Real-World Data
Julian C. Hong, MD, MS; Atul J. Butte, MD, PhD
JAMA Netw Open. 2021;4(7):e2117826. doi:10.1001/jamanetworkopen.2021.17826
ONCOLOGY
Kathleen M. Decker, PhD; Pascal Lambert, MSc; Jen Bravo, MSc; et al.
This cohort study examines changes in the incidence of colorectal cancer from 1992 to 2016 in individuals in Canada by age group and income quintile.
JAMA Netw Open. 2021;4(7):e2117556. doi:10.1001/jamanetworkopen.2021.17556
NEUROLOGY
Philip S. Insel, PhD; Brian S. Mohlenhoff, MD; Thomas C. Neylan, MD; et al.
This cross-sectional study evaluates the associations between daytime and nighttime sleep duration with regional β-amyloid pathology in older cognitively unimpaired adults.
JAMA Netw Open. 2021;4(7):e2117573. doi:10.1001/jamanetworkopen.2021.17573
ORTHOPEDICS
Anne R. Bass, MD; Huong T. Do, MA; Bella Mehta, MBBS, MS, MD; et al.
This cohort study assesses the risk of septic and aseptic revision total knee replacement in Black and White patients and examines interactions among race and socioeconomic and hospital-related variables associated with revision risk.
JAMA Netw Open. 2021;4(7):e2117581. doi:10.1001/jamanetworkopen.2021.17581
EMERGENCY MEDICINE
Jason S. Haukoos, MD, MSc; Michael S. Lyons, MD, MPH; Richard E. Rothman, MD, PhD; et al.
This randomized clinical trial examines 76 561 emergency department patient visits to compare effectiveness of targeted and nontargeted HIV screening strategies for finding new diagnoses.
JAMA Netw Open. 2021;4(7):e2117763. doi:10.1001/jamanetworkopen.2021.17763
MEDICAL EDUCATION
Helen Xun, MD; Jonlin Chen, BS; Alexander H. Sun, MD; et al.
This survey study uses data from a national survey of US adults to investigate perceptions of physician professionalism based on attire and whether gender biases exist.
JAMA Netw Open. 2021;4(7):e2117779. doi:10.1001/jamanetworkopen.2021.17779
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Invited Commentary
Has the Physician’s White Coat Seen Its Day?
Amalia Cochran, MD; Gilbert R. Upchurch Jr, MD
JAMA Netw Open. 2021;4(7):e2119881. doi:10.1001/jamanetworkopen.2021.19881
HEALTH POLICY
Bettye A. Apenteng, PhD; Samuel T. Opoku, MBChB, PhD; Charles Owens, MSA; et al.
This cross-sectional study examines the association of Georgia’s Rural Hospital Tax Credit Program with the financial health of participating rural hospitals.
JAMA Netw Open. 2021;4(7):e2117791. doi:10.1001/jamanetworkopen.2021.17791
HEALTH INFORMATICS
Evan W. Orenstein, MD; Omar ElSayed-Ali, MD; Swaminathan Kandaswamy, PhD; et al.
This quality improvement study evaluates a clinical decision support strategy to increase the proportion of eligible hospitalized children who receive a seasonal influenza vaccine prior to inpatient discharge.
JAMA Netw Open. 2021;4(7):e2117809. doi:10.1001/jamanetworkopen.2021.17809
PEDIATRICS
Peter J. Gill, MD, DPhil; Mohammed Rashidul Anwar, MBBS, MSc; Thaksha Thavam, MSc; et al.
This cohort study examines prevalence, cost, and variation in cost of hospitalizations in US pediatric hospitals.
JAMA Netw Open. 2021;4(7):e2117816. doi:10.1001/jamanetworkopen.2021.17816
HEALTH POLICY
Christina A. Nguyen, AB; Lauren G. Gilstrap, MD, MPH; Michael E. Chernew, PhD; et al.
This cross-sectional study assesses the use of consistently low performance scores for physician groups across multiple performance measures and over multiple years to identify low-quality physician groups.
JAMA Netw Open. 2021;4(7):e2117954. doi:10.1001/jamanetworkopen.2021.17954
CARDIOLOGY
Akash Goyal, MD; Tony Schibler, MPA; Brooke Alhanti, PhD; et al.
This cohort study uses data from 9 randomized clinical cardiovascular trials to assess the start-up times of various milestones for North American research sites and how these metrics vary by time and regulatory process.
JAMA Netw Open. 2021;4(7):e2117963. doi:10.1001/jamanetworkopen.2021.17963
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Invited Commentary
Reconfiguring the Cardiovascular Clinical Trial Enterprise in the United States
Deepak L. Bhatt, MD, MPH
JAMA Netw Open. 2021;4(7):e2118176. doi:10.1001/jamanetworkopen.2021.18176
PUBLIC HEALTH
Daniel R. George, PhD, MSc; Bethany Snyder, MPH; Lauren J. Van Scoy, MD; et al.
This qualitative study explores the perceptions of people residing in rural and urban areas with high prevalence of diseases of despair regarding potential causes and intervention strategies.
JAMA Netw Open. 2021;4(7):e2118134. doi:10.1001/jamanetworkopen.2021.18134
CARDIOLOGY
Samuel Blais, BSc; Ariane Marelli, MD, MPH; Alain Vanasse, MD, PhD; et al.
This cohort study compares the long-term outcomes associated with valve-sparing procedures vs transannular patches for correction of tetralogy of Fallot.
JAMA Netw Open. 2021;4(7):e2118141. doi:10.1001/jamanetworkopen.2021.18141
PUBLIC HEALTH
Elizabeth A. Samuels, MD, MPH, MHS; Lilla Orr, MA; Elizabeth B. White, BA; et al.
This cohort study investigates the association between health care utilization and the so-called Muslim ban executive order for people born in Muslim-majority countries and living in Minneapolis-St. Paul, Minnesota.
JAMA Netw Open. 2021;4(7):e2118216. doi:10.1001/jamanetworkopen.2021.18216
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Invited Commentary
Anti-Immigrant Rhetoric and Policy as Manifestations of Structural Racism—Implications for Advancing Health Equity
Nadia Islam, PhD; Naheed Ahmed, PhD
JAMA Netw Open. 2021;4(7):e2118299. doi:10.1001/jamanetworkopen.2021.18299
SUBSTANCE USE AND ADDICTION
Paul J. Joudrey, MD, MPH; Zoe M. Adams, BA; Paxton Bach, MD, MSc; et al.
This cross-sectional study examines the proportion of clinics accepting new patients with opioid use disorder and time until first appointment in the US and Canada.
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JAMA Netw Open. 2021;4(7):e2118223. doi:10.1001/jamanetworkopen.2021.18223
HEALTH POLICY
Suze G. Berkhout, MD, PhD; Kathleen A. Sheehan, MD, DPhil; Susan E. Abbey, MD
This qualitative analysis uses an online COVID-19 forum available to employees at a large health care institution to examine sources of distress and concern for health care workers in Canada during the COVID-19 pandemic.
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JAMA Netw Open. 2021;4(7):e2118425. doi:10.1001/jamanetworkopen.2021.18425
ONCOLOGY
Joseph M. Unger, PhD, MS; Hong Xiao, PhD; Michael LeBlanc, PhD; et al.
This cohort study examines the experience of cancer clinical trial enrollment 1 year after the COVID-19 outbreak.
has active quiz
JAMA Netw Open. 2021;4(7):e2118433. doi:10.1001/jamanetworkopen.2021.18433
GASTROENTEROLOGY AND HEPATOLOGY
Martin C. S. Wong, MD, MPH; Junjie Huang, MD, MSc; Paul S. F. Chan, MEd; et al.
This cohort study uses data from national and global cancer registries to evaluate the incidence and mortality of gastric cancer between 1980 and 2018 and compares the global incidence between younger and older populations.
JAMA Netw Open. 2021;4(7):e2118457. doi:10.1001/jamanetworkopen.2021.18457
ONCOLOGY
Antonio Avallone, MD; Maria C. Piccirillo, MD; Guglielmo Nasti, MD; et al.
This randomized clinical trial compares outcomes of concomitant and sequential administration of bevacizumab in combination with standard oxaliplatin-based regimens in untreated or single line–treated patients with metastatic colorectal cancer.
JAMA Netw Open. 2021;4(7):e2118475. doi:10.1001/jamanetworkopen.2021.18475
HEALTH POLICY
Lauren Bifulco, MPH; Daren R. Anderson, MD; Mary L. Blankson, DNP, APRN, FNP-C; et al.
This cross-sectional study evaluated a 2-item tool used to assess patients’ pain and its interference with activities of daily living in a primary care setting.
JAMA Netw Open. 2021;4(7):e2118495. doi:10.1001/jamanetworkopen.2021.18495
ONCOLOGY
Sara R. Marquis, MPH; Jennifer K. Logue, BS; Helen Y. Chu, MD, MPH; et al.
This cross-sectional study examines serological test results for protective antibodies for measles and mumps among patients with hematologic malignant neoplasm or solid tumors.
JAMA Netw Open. 2021;4(7):e2118508. doi:10.1001/jamanetworkopen.2021.18508
PSYCHIATRY
Kristina Aspvall, PhD; Filipa Sampaio, PhD; Fabian Lenhard, PhD; et al.
This economic evaluation assesses the cost-effectiveness of guided internet-delivered cognitive behavioral therapy implemented within a stepped-care model compared with in-person cognitive behavioral therapy for young people with obsessive-compulsive disorder.
JAMA Netw Open. 2021;4(7):e2118516. doi:10.1001/jamanetworkopen.2021.18516
ONCOLOGY
Siyuan Xu, MD; Hui Huang, MD; Jiaxin Qian, MD; et al.
his cohort study assesses the prevalence of and outcomes associated with Hashimoto thyroiditis among adults with papillary thyroid cancer.
JAMA Netw Open. 2021;4(7):e2118526. doi:10.1001/jamanetworkopen.2021.18526
CARDIOLOGY
Kyndaron Reinier, PhD, MPH; Arayik Sargsyan, MPH; Harpriya S. Chugh, BS; et al.
This cohort study examines the incidence of sudden cardiac arrest and risk factors by race/ethnicity in residents of Ventura County, California.
JAMA Netw Open. 2021;4(7):e2118537. doi:10.1001/jamanetworkopen.2021.18537
INFECTIOUS DISEASES
Jonne J. Sikkens, MD, PhD; David T. P. Buis, MD; Edgar J. G. Peters, MD, PhD; et al.
This cohort study investigates prevalence and transmission routes of SARS-CoV-2 infection among hospital health care workers in the Netherlands using serologic surveillance and phylogenetic and epidemiological analyses.
has active quiz
JAMA Netw Open. 2021;4(7):e2118554. doi:10.1001/jamanetworkopen.2021.18554
GASTROENTEROLOGY AND HEPATOLOGY
Shahrad Hakimian, MD; Daniel Raines, MD; George Reed, PhD; et al.
This cohort study examines the use of video capsule endoscopy vs standard invasive diagnostic procedures to evaluate gastrointestinal (GI) bleeding in patients with COVID-19.
has active quiz
JAMA Netw Open. 2021;4(7):e2118796. doi:10.1001/jamanetworkopen.2021.18796
EMERGENCY MEDICINE
Eden Engel-Rebitzer, BA; Abby R. Dolan, BA; Shoshana V. Aronowitz, PhD, FNP-BC; et al.
This secondary analysis of data from a randomized clinical trial characterizes racial disparities in opioid prescribing and examines whether a clinician intervention describing patient treatment preference and risk of opioid misuse was able to mitigate disparities among patients with acute pain.
JAMA Netw Open. 2021;4(7):e2118801. doi:10.1001/jamanetworkopen.2021.18801
DIABETES AND ENDOCRINOLOGY
Zhangling Chen, MD, PhD; Djawad Radjabzadeh, MSc; Lianmin Chen, MSc; et al.
This cross-sectional study assesses whether gut microbial taxa play a role in the development of type 2 diabetes using data from 2 Dutch population-based prospective cohorts.
JAMA Netw Open. 2021;4(7):e2118811. doi:10.1001/jamanetworkopen.2021.18811
NEUROLOGY
Hong-Qiu Gu, PhD; Xin Yang, MD; Chun-Juan Wang, MD; et al.
This quality improvement study assesses adherence to guideline-recommended oral anticoagulants, the temporal improvement in adherence, and the risk factors associated with oral anticoagulant prescriptions.
JAMA Netw Open. 2021;4(7):e2118816. doi:10.1001/jamanetworkopen.2021.18816
PEDIATRICS
Gyeyoon Yim, ScD; Andrea Roberts, PhD; Alberto Ascherio, MD, DrPH; et al.
This cohort study analyzes data from mother-daughter dyad participants in the Nurses’ Health Study II to assess whether a woman’s weight before or during pregnancy is associated with attention-deficit/hyperactivity disorder (ADHD) in grandchildren.
JAMA Netw Open. 2021;4(7):e2118824. doi:10.1001/jamanetworkopen.2021.18824
STATISTICS AND RESEARCH METHODS
Daniel J. Morgan, MD, MS; Lisa Pineles, MA; Jill Owczarzak, PhD; et al.
This survey study explores clinicians’ conceptualizations of the chance that treatments will decrease the risk of disease outcomes for individual hypothetical patients.
JAMA Netw Open. 2021;4(7):e2119747. doi:10.1001/jamanetworkopen.2021.19747
HEMATOLOGY
Zhe Wang, MS; Xiaoyu Wang, MS; Zhen Wang, MS; et al.
This systematic review and meta-analysis examines the relative risk of hepatotoxicity of new-generation BCR-ABL fusion oncoprotein tyrosine kinase inhibitors (TKIs) vs imatinib among patients with chronic myeloid leukemia.
JAMA Netw Open. 2021;4(7):e2120165. doi:10.1001/jamanetworkopen.2021.20165