PUBLIC HEALTH
Katherine A. East, PhD; Jessica L. Reid, MSc; Robin Burkhalter, MMath; et al.
This survey study evaluates the outcomes of menthol cigarette bans on youth menthol cigarette smoking and characterizes youth menthol cigarette smokers in terms of demographics and cigarette consumption and dependence.
JAMA Netw Open. 2022;5(5):e2210029. doi:10.1001/jamanetworkopen.2022.10029
GLOBAL HEALTH
Mayanka Ambade, PhD; Rakesh Sarwal, PhD; Nachiket Mor, PhD; et al.
This cross-sectional study investigates the contributions of doctor consultations, medicines, diagnostic tests, and nonmedical costs to out-of-pocket expenditure on health care in India.
JAMA Netw Open. 2022;5(5):e2210040. doi:10.1001/jamanetworkopen.2022.10040
MEDICAL EDUCATION
Joseph Bledsoe, MD; Ithan D. Peltan, MD, MSc; R. J. Bunnell, MD; et al.
This comparative effectiveness research study investigates the association of order substitutions and education for the use of lactated Ringer solution with major adverse kidney events in an integrated health care system.
JAMA Netw Open. 2022;5(5):e2210046. doi:10.1001/jamanetworkopen.2022.10046
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Invited Commentary
Intravenous Fluids—A Test Case for Learning Health Systems
Matthew W. Semler, MD, MSc
JAMA Netw Open
INFECTIOUS DISEASES
Tat Ming Ng, PharmD; Shi Thong Heng, MPH; Boon Hou Chua, BSc(Pharm); et al.
This cohort study examines associations of sequential implementation of antimicrobial stewardship initiatives with trends in antibiotic use and incidence of multidrug resistant organisms.
JAMA Netw Open. 2022;5(5):e2210180. doi:10.1001/jamanetworkopen.2022.10180
GERIATRICS
Kelly Birtwell, PhD; Claire Planner, PhD; Alexander Hodkinson, PhD; et al.
This systematic review and meta-analysis examines the association of transitional care interventions with hospital and emergency department readmissions for patients 65 years and older who are transitioning in and out of long-term care facilities and explores factors that potentially mitigate the outcomes and implementation of transitional care interventions.
JAMA Netw Open. 2022;5(5):e2210192. doi:10.1001/jamanetworkopen.2022.10192
ONCOLOGY
Soudabeh Fazeli, MD, MPH; Bradley S. Snyder, MS; Ilana F. Gareen, PhD, MPH; et al.
This cohort study examines the preferences of women for treatment of ductal carcinoma in situ on the basis of magnetic resonance imaging findings and surgeon recommendations.
JAMA Netw Open. 2022;5(5):e2210331. doi:10.1001/jamanetworkopen.2022.10331
NEPHROLOGY
Ichiei Narita, MD, PhD; Yoshiharu Tsubakihara, MD, PhD; Takuma Uchiyama, MSc; et al.
This randomized clinical trial evaluates the efficacy, dose response, safety, and pharmacokinetics of 3 different doses of difelikefalin compared with placebo for the treatment of moderate to severe pruritus among Japanese patients receiving hemodialysis.
JAMA Netw Open. 2022;5(5):e2210339. doi:10.1001/jamanetworkopen.2022.10339
PUBLIC HEALTH
Hongying Shi, PhD; Tianyi Huang, ScD, MSc; Eva S. Schernhammer, MD, DrPH; et al.
This cohort study of female nurses examines the association between rotating night shift work and healthy aging after 24 years of follow-up in the Nurses’ Health Study.
JAMA Netw Open. 2022;5(5):e2210450. doi:10.1001/jamanetworkopen.2022.10450
EMERGENCY MEDICINE
Kelly R. Bergmann, DO, MS; Amanda Nickel, MPH; Matt Hall, PhD; et al.
This cross-sectional study assesses whether neighborhood opportunity is associated with type 1 diabetes–related outcomes by race and ethnicity, including readmissions for diabetic ketoacidosis and co-occurring acute kidney injury and cerebral edema.
JAMA Netw Open. 2022;5(5):e2210456. doi:10.1001/jamanetworkopen.2022.10456
DIABETES AND ENDOCRINOLOGY
Jennifer M. Ladd, MD; Atul Sharma, MD, MSc; Elham Rahme, PhD; et al.
This cohort study compares use of insulin pumps in children with type 1 diabetes in Québec, Canada, where full funding is available, with use in Manitoba, Canada, where funding is partial.
JAMA Netw Open. 2022;5(5):e2210464. doi:10.1001/jamanetworkopen.2022.10464
NEUROLOGY
Chih-Ching Liu, PhD; Chien-Hui Liu, RN, MSc; Kun-Chia Chang, MD, PhD; et al.
This cohort study assesses the risk of hospitalization for motor vehicle crash injuries among Taiwanese adults with young-onset dementia compared with age-matched individuals without dementia.
JAMA Netw Open. 2022;5(5):e2210474. doi:10.1001/jamanetworkopen.2022.10474
PEDIATRICS
Andrea S. Richardson, PhD, MPH; Margaret M. Weden, PhD; Irineo Cabreros, PhD; et al.
This cohort study uses data from 2 nationally representative cohorts of US kindergarteners followed up through grade 5 to assess whether body mass growth differed after implementation of the Healthy, Hunger-Free Kids Act of 2010 among children in low-income families.
JAMA Netw Open. 2022;5(5):e2210480. doi:10.1001/jamanetworkopen.2022.10480
EMERGENCY MEDICINE
Sung Hwa Kim, BS; Yoonsuk Lee, MD; Soo Kang, MD; et al.
This prognostic study develops and validates a clinical scoring system for predicting poor neurocognitive outcomes after acute carbon monoxide poisoning.
JAMA Netw Open. 2022;5(5):e2210552. doi:10.1001/jamanetworkopen.2022.10552
INFECTIOUS DISEASES
Jesse Papenburg, MD, MSc; Jonathon R. Campbell, PhD; Chelsea Caya, MScPH; et al.
This cohort study assesses the execution and interpretation of SARS-CoV-2 rapid antigen detection tests when performed by untrained persons an intended-use setting.
has active quiz
JAMA Netw Open. 2022;5(5):e2210559. doi:10.1001/jamanetworkopen.2022.10559
NEUROLOGY
Yi Chen, MD; Xiaoxian Gong, MD; Wansi Zhong, MD; et al.
This quality improvement study evaluates the outcomes associated with a program to improve clinician adherence to management guidelines for acute ischemic stroke in hospitals in China.
JAMA Netw Open. 2022;5(5):e2210596. doi:10.1001/jamanetworkopen.2022.10596
GERIATRICS
Phillip H. Hwang, PhD, MPH; W. T. Longstreth Jr, MD; Stephen M. Thielke, MD; et al.
This cohort study evaluates whether concurrent hearing and vision deficits, ie, dual sensory impairment, is associated with incident dementia in older adults.
JAMA Netw Open. 2022;5(5):e2210734. doi:10.1001/jamanetworkopen.2022.10734
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Invited Commentary
New Insights Into Sensory Impairment and Dementia Risk
Nicholas S. Reed, AuD; Esther S. Oh, MD, PhD
JAMA Netw Open
PSYCHIATRY
Katlyn Nemani, MD; Sharifa Z. Williams, DrPH; Mark Olfson, MD; et al.
This cohort study evaluates the associations between the use of psychotropic medications and the risk of COVID-19 infection among adults with serious mental illness receiving long-term inpatient psychiatric treatment.
has active quiz
JAMA Netw Open. 2022;5(5):e2210743. doi:10.1001/jamanetworkopen.2022.10743
MEDICAL EDUCATION
Tyra Fainstad, MD; Adrienne Mann, MD; Krithika Suresh, PhD; et al.
This pilot randomized clinical trial assesses whether a structured professional group coaching program for female resident physicians would lead to decreased burnout.
JAMA Netw Open. 2022;5(5):e2210752. doi:10.1001/jamanetworkopen.2022.10752
PEDIATRICS
Valerie Bailey, FNP; Dorothy M. Beke, CPNP-PC/AC; Jennifer M. Snaman, MD; et al.
This cross-sectional study evaluates the Pediatric Intensive Care Unit Quality of Dying and Death instrument and examines differences between disciplines and end-of-life circumstances.
JAMA Netw Open. 2022;5(5):e2210762. doi:10.1001/jamanetworkopen.2022.10762
OCCUPATIONAL HEALTH
Susannah G. Rowe, MD, MPH; Miriam T. Stewart, MD; Sam Van Horne, MFA, PhD; et al.
This survey study evaluates the prevalence and sources of mistreatment among physicians and associations between mistreatment, occupational well-being, and physicians’ perceptions of protective workplace systems.
JAMA Netw Open. 2022;5(5):e2210768. doi:10.1001/jamanetworkopen.2022.10768
DIVERSITY, EQUITY, AND INCLUSION
Beth Jones, MSQM; Pam James, MS; Ganga Vijayasiri, PhD; et al.
This survey study evaluates patient perspectives on care transition experiences from hospitals or skilled nursing facilities to home.
JAMA Netw Open. 2022;5(5):e2210774. doi:10.1001/jamanetworkopen.2022.10774
INFECTIOUS DISEASES
Koichi Furukawa, MD; Lidya Handayani Tjan, MD, PhD; Yukiya Kurahashi, MD; et al.
This cohort study investigates the induction of neutralizing antibodies against the SARS-CoV-2 Omicron variant after 2 and 3 doses of the BNT162b2 mRNA vaccine among recipients of different ages.
JAMA Netw Open. 2022;5(5):e2210780. doi:10.1001/jamanetworkopen.2022.10780
SURGERY
Meng Kong, MD; Hongyuan Chen, MD; Keshu Shan, MD; et al.
This individual participant data meta-analysis uses time-to-event data to compare the long-term oncologic outcomes after laparoscopic and open surgery for adult patients with rectal cancer.
JAMA Netw Open. 2022;5(5):e2210861. doi:10.1001/jamanetworkopen.2022.10861
ONCOLOGY
Emma Khoury, MRes; Sarah Nevitt, BSc, MSc, PhD; William Rohde Madsen, BSc; et al.
This systematic review and meta-analysis analyzed the association of age, sex, and cancer types and therapies with survival rates among patients with both cancer and COVID-19 diagnosis.
JAMA Netw Open. 2022;5(5):e2210880. doi:10.1001/jamanetworkopen.2022.10880
DIVERSITY, EQUITY, AND INCLUSION
Sonal Batra, MD, MST; Julie Orban, MPH; Hexuan Zhang, PhD; et al.
This survey study describes the current state of social mission commitment within dental, medical, and nursing schools in the US and examines how social mission engagement and performance compares across school types.
JAMA Netw Open. 2022;5(5):e2210900. doi:10.1001/jamanetworkopen.2022.10900
PUBLIC HEALTH
Yu Wang, MSPH; Zongshuan Duan, PhD; Sherry L. Emery, PhD; et al.
This cross-sectional study examines differences in intentions and attempts to quit smoking by sexual minority status among smokers exposed to the Tips From Former Smokers campaign.
JAMA Netw Open. 2022;5(5):e2211060. doi:10.1001/jamanetworkopen.2022.11060
SURGERY
Karolina Eklöv, MD; Jonas Nygren, MD; Sven Bringman, MD; et al.
This cohort study investigates changes in the treatment of colorectal cancer (CRC) and short-term outcomes during the first wave of the COVID-19 pandemic in Sweden, compared with the year before.
JAMA Netw Open. 2022;5(5):e2211065. doi:10.1001/jamanetworkopen.2022.11065
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Invited Commentary
Trends in Colorectal Surgery During the COVID-19 Pandemic
Michael R. Freund, MD; Steven D. Wexner, MD
JAMA Netw Open
CARDIOLOGY
Russell V. Luepker, MD; Milton Eder, PhD; John R. Finnegan, PhD; et al.
This nonrandomized controlled trial examines the association of a multimedia communication with the public and education for health care professionals with guideline-based use of aspirin for prevention of cardiovascular disease (CVD).
JAMA Netw Open. 2022;5(5):e2211107. doi:10.1001/jamanetworkopen.2022.11107
INFECTIOUS DISEASES
Brad Spellberg, MD; Gloria Aggrey, MD; Meghan B. Brennan, MD; et al.
This consensus statement and systematic review from the WikiGuidelines Group, an online collaborative research initiative, examines standards of evidence for pyogenic osteomyelitis care and offers clinical recommendations.
JAMA Netw Open. 2022;5(5):e2211321. doi:10.1001/jamanetworkopen.2022.11321
PHARMACY AND CLINICAL PHARMACOLOGY
Nicholas J. Mercuro, PharmD; Corey J. Medler, PharmD; Rachel M. Kenney, PharmD; et al.
This nonrandomized, stepped-wedge quality improvement study assesses a pharmacist-led antimicrobial stewardship program to review and identify inappropriate prescriptions at hospital discharge and evaluate the association of the intervention with optimized therapy and adverse events among patients with common infections.
JAMA Netw Open. 2022;5(5):e2211331. doi:10.1001/jamanetworkopen.2022.11331
DIVERSITY, EQUITY, AND INCLUSION
Ben Li, MD; Naomi Eisenberg, PT, MEd, CCRP; Miranda Witheford, MD, PhD; et al.
This cohort study examines differences between men and women in survival after surgery for ruptured abdominal aortic aneurysm.
JAMA Netw Open. 2022;5(5):e2211336. doi:10.1001/jamanetworkopen.2022.11336
PSYCHIATRY
Kevin Y. Xu, MD, MPH; Carrie M. Mintz, MD; Ned Presnall, MSW; et al.
This comparative effectiveness study evaluates distribution of buprenorphine and naltrexone initiation among individuals with opioid use disorder with or without cooccurring substance use disorder.
JAMA Netw Open. 2022;5(5):e2211363. doi:10.1001/jamanetworkopen.2022.11363
PSYCHIATRY
A-La Park, MSc; Tamara Waldmann, PhD; Markus Kösters, PhD; et al.
This economic evaluation assesses whether providing the World Health Organization’s Self-Help Plus intervention combined with enhanced usual care is cost-effective compared with enhanced usual care alone for conflict-exposed Syrian refugees or asylum seekers hosted in Turkey.
JAMA Netw Open. 2022;5(5):e2211489. doi:10.1001/jamanetworkopen.2022.11489
NEUROLOGY
Andreas Tolf, MD; Anna Wiberg, MD, PhD; Malin Müller, PhD; et al.
This cohort study conducted at a specialized multiple sclerosis (MS) clinic investigates factors associated with serological response to tozinameran in patients with MS receiving rituximab.
JAMA Netw Open. 2022;5(5):e2211497. doi:10.1001/jamanetworkopen.2022.11497
PSYCHIATRY
Craig J. Bryan, PsyD; AnnaBelle O. Bryan, MS; Heather M. Wastler, PhD; et al.
This survey study investigates whether patterns of reported suicidal ideation, planning, and behavior differ among US adults who own a firearm vs those who do not own a firearm.
JAMA Netw Open. 2022;5(5):e2211510. doi:10.1001/jamanetworkopen.2022.11510
NEUROLOGY
Kristine Broglio, MS; William J. Meurer, MD, MS; Valerie Durkalski, PhD; et al.
This cohort study compares the use of a bayesian vs frequentist trial design in the Stroke Hyperglycemia Insulin Network Effort trial.
JAMA Netw Open. 2022;5(5):e2211616. doi:10.1001/jamanetworkopen.2022.11616
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Invited Commentary
Empirical Evaluations of Clinical Trial Designs
Lorenzo Trippa, PhD; Sergio Bacallado, PhD
JAMA Netw Open
GERIATRICS
Anoop T. Balachandran, PhD; James Steele, PhD; Daniel Angielczyk, MS; et al.
This systematic review and meta-analysis compares strength training vs power training for improving physical function in adults aged 60 years and older.
JAMA Netw Open. 2022;5(5):e2211623. doi:10.1001/jamanetworkopen.2022.11623
SUBSTANCE USE AND ADDICTION
Carrie M. Mintz, MD; Kevin Y. Xu, MD, MPH; Ned J. Presnall, MSW; et al.
This cohort study with a case-crossover analytical design examines the associations between prescription stimulant use and drug-related poisonings and buprenorphine treatment retention among patients with opioid use disorder.
JAMA Netw Open. 2022;5(5):e2211634. doi:10.1001/jamanetworkopen.2022.11634
STATISTICS AND RESEARCH METHODS
Hui Zhou, MSc; Mi Yao, MD; Xiaodan Gu, MBBS; et al.
This cross-sectional study evaluates the use of patient-reported outcome instruments as primary and secondary outcomes in randomized clinical trials conducted in China.
JAMA Netw Open. 2022;5(5):e2211644. doi:10.1001/jamanetworkopen.2022.11644
SUBSTANCE USE AND ADDICTION
Gwen T. Lapham, PhD, MPH, MSW; Theresa E. Matson, MPH; David S. Carrell, PhD; et al.
This survey study compares the use of cannabis for medical purposes as reported in electronic health records (EHRs) with use reported in a confidential survey.
JAMA Netw Open. 2022;5(5):e2211677. doi:10.1001/jamanetworkopen.2022.11677
CRITICAL CARE MEDICINE
Claire Corrigan, MBChB; Graeme Duke, MBBS, MD; Johnny Millar, MBChB, PhD; et al.
This cohort study investigates the rate of intensive care admissions with deliberate self-harm among children and adolescents in Australia during the SARS-CoV-2 outbreak.
JAMA Netw Open. 2022;5(5):e2211692. doi:10.1001/jamanetworkopen.2022.11692
DIABETES AND ENDOCRINOLOGY
Josh M. Evron, MD; Scott L. Hummel, MD, MS; David Reyes-Gastelum, MS; et al.
This cohort study uses data from the Veterans Health Administration Corporate Data Warehouse database to evaluate the association between the intensity of thyroid hormone treatment and cardiovascular mortality.
JAMA Netw Open. 2022;5(5):e2211863. doi:10.1001/jamanetworkopen.2022.11863
ONCOLOGY
Laura Burgess, MSc, MD; Christopher M. Aldrighetti, BS; Anushka Ghosh, BS; et al.
This cross-sectional study evaluates prostate cancer–specific mortality rates between 1999 and 2019, comparing trends in rates before and after the change in the 2012 US Preventive Services Task Force prostate-specific antigen screening guideline.
JAMA Netw Open. 2022;5(5):e2211869. doi:10.1001/jamanetworkopen.2022.11869
DIVERSITY, EQUITY, AND INCLUSION
Kevin A. Jenkins, PhD; Shimrit Keddem, PhD; Selamawite B. Bekele, BA; et al.
This qualitative study investigates the health care experiences and racial discrimination encountered by Black veterans with chronic kidney disease in the US.
JAMA Netw Open. 2022;5(5):e2211900. doi:10.1001/jamanetworkopen.2022.11900
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Invited Commentary
Centering Black Men With Kidney Disease
Tessa K. Novick, MD, MSW, MHS; Deidra C. Crews, MD, ScM
JAMA Netw Open
CARDIOLOGY
Kunihiro Matsushita, MD, PhD; Yumin Gao, ScM; Jonathan Rubin, MD, MHS; et al.
This cohort study evaluates the risk of cardiovascular mortality, coronary heart disease, stroke, heart failure, and atrial fibrillation among Black individuals with aortic stenosis as well as trace or mild aortic regurgitation or mitral regurgitation.
JAMA Netw Open. 2022;5(5):e2211946. doi:10.1001/jamanetworkopen.2022.11946
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Invited Commentary
The Spectrum of Valvular Heart Disease and the Importance of “Mild”
Rishi Puri, MBBS, PhD; Iryna Dykun, MD; Ankur Kalra, MD
JAMA Netw Open
INFECTIOUS DISEASES
Aziz Mezlini, PhD; Allison Shapiro, PhD; Eric J. Daza, DrPH, MPS; et al.
This cohort study estimates the true burden of influenza-like illness in the US population using a surrogate measure of daily steps lost as measured by commercial wearable sensors.
JAMA Netw Open. 2022;5(5):e2211958. doi:10.1001/jamanetworkopen.2022.11958
PEDIATRICS
Louis Ehwerhemuepha, PhD; Bradley Roth, BS; Anita K. Patel, MD; et al.
This cohort study evaluates the association of congenital and acquired cardiovascular conditions with severity of COVID-19 among pediatric patients in the US.
has active quiz
JAMA Netw Open. 2022;5(5):e2211967. doi:10.1001/jamanetworkopen.2022.11967
HEALTH INFORMATICS
Yuanfang Ren, PhD; Tyler J. Loftus, MD; Shounak Datta, PhD; et al.
This prognostic study examines whether an artificial intelligence platform is able to accurately predict postoperative complications using automated real-time electronic health record data and provide automated outputs directly to surgeons’ mobile devices.
JAMA Netw Open. 2022;5(5):e2211973. doi:10.1001/jamanetworkopen.2022.11973
PUBLIC HEALTH
Elizabeth A. Pleasants, MPH; Alice F. Cartwright, MPH; Ushma D. Upadhyay, PhD, MPH
This cohort study investigates the association between distance to the nearest abortion facility and abortion and pregnancy outcome among individuals seeking abortion care and information online.
JAMA Netw Open. 2022;5(5):e2212065. doi:10.1001/jamanetworkopen.2022.12065
SURGERY
Kevin Yei, BS; Asma Mathlouthi, MD; Isaac Naazie, MD, MPH; et al.
This cohort study compares long-term outcomes after endovascular vs open abdominal aortic aneurysm repair.
JAMA Netw Open. 2022;5(5):e2212081. doi:10.1001/jamanetworkopen.2022.12081
PSYCHIATRY
Drew Wilimitis, BS; Robert W. Turer, MD, MS; Michael Ripperger, BE; et al.
This cohort study evaluates the respective and combined abilities of a real-time machine learning model and the Columbia Suicide Severity Rating Scale to predict suicide attempt and suicidal ideation among adults.
JAMA Netw Open. 2022;5(5):e2212095. doi:10.1001/jamanetworkopen.2022.12095
ONCOLOGY
Marquita W. Lewis-Thames, PhD, MPH, MS; Marvin E. Langston, PhD, MPH; Saira Khan, PhD, MPH; et al.
This cross-sectional study uses an epidemiological assessment to examine rural-urban trends in the 5-year survival of patients with lung, prostate, breast, and colorectal cancers.
JAMA Netw Open. 2022;5(5):e2212246. doi:10.1001/jamanetworkopen.2022.12246
ONCOLOGY
Nibras Ahmed, BS; Yasaswi Vengalasetti, MS; Alyson Haslam, PhD; et al.
This cross-sectional study of clinical trials of cancer drugs compares rates of treatment discontinuation because of adverse events or withdrawal in an adjuvant setting vs a metastatic setting.
JAMA Netw Open. 2022;5(5):e2212327. doi:10.1001/jamanetworkopen.2022.12327
INFECTIOUS DISEASES
Amanda Brown Marusiak, MPH; Brandon D. Hollingsworth, PhD; Haley Abernathy, BS; et al.
This cross-sectional study examines patterns of diagnostic testing for and incidence of tick-borne diseases in North Carolina.
JAMA Netw Open. 2022;5(5):e2212334. doi:10.1001/jamanetworkopen.2022.12334
EMERGENCY MEDICINE
David R. Vinson, MD; Scott D. Casey, MD, MS; Peter L. Vuong, DO; et al.
This cohort study evaluates the sustainability of recommended site-of-care decision-making support 4 years after an initial intervention to increase outpatient management of acute pulmonary embolism among patients presenting to the emergency department (ED).
JAMA Netw Open. 2022;5(5):e2212340. doi:10.1001/jamanetworkopen.2022.12340
ONCOLOGY
Nicholas H. Chakiryan, MD; L. Robert Gore, PhD; Richard R. Reich, PhD; et al.
This cohort study of patients with metastatic clear cell renal cell carcinoma assesses whether cytoreductive nephrectomy is associated with improved overall survival.
JAMA Netw Open. 2022;5(5):e2212347. doi:10.1001/jamanetworkopen.2022.12347
NUTRITION, OBESITY, AND EXERCISE
Kerri N. Boutelle, PhD; Dawn M. Eichen, PhD; Carol B. Peterson, PhD; et al.
This randomized clinical trial compares the effects of regulation of cues weight loss treatment with behavioral weight loss treatment on body mass index (BMI) in adults with overweight or obesity.
JAMA Netw Open. 2022;5(5):e2212354. doi:10.1001/jamanetworkopen.2022.12354
CARDIOLOGY
Mai N. Nguyen-Huynh, MD, MAS; Joseph D. Young, MD; Bruce Ovbiagele, MD; et al.
This cluster randomized clinical trial evaluates the effectiveness of a lifestyle coaching intervention vs an enhanced pharmacotherapy protocol compared with usual care in controlling blood pressure in Black adults with persistent uncontrolled hypertension.
JAMA Netw Open. 2022;5(5):e2212397. doi:10.1001/jamanetworkopen.2022.12397
SUBSTANCE USE AND ADDICTION
Holly J. Lanham, PhD, MBA; Jennifer Papac, MD; Daniela I. Olmos, BA; et al.
This survey study examines barriers to and facilitators of obtaining a waiver to prescribe buprenorphine among office-based clinicians in Texas.
JAMA Netw Open. 2022;5(5):e2212419. doi:10.1001/jamanetworkopen.2022.12419
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Editorial
Beyond the Waiver: Multilevel Interventions Needed to Expand Buprenorphine Treatment
Elizabeth A. Samuels, MD, MPH, MHS; Alister F. Martin, MD, MPP
JAMA Netw Open
MEDICAL EDUCATION
Abbas M. Hassan, MD; Malke Asaad, MD; Nikhil R. Shah, MD; et al.
This cohort study compares outcomes of abdominal wall reconstruction performed by surgical fellows with those of procedures performed by assistant, associate, and senior-level professors.
JAMA Netw Open. 2022;5(5):e2212444. doi:10.1001/jamanetworkopen.2022.12444
HEALTH POLICY
Mayookha Mitra-Majumdar, MPH; Simon J. Gunter, MPhil; Aaron S. Kesselheim, MD, JD, MPH; et al.
This cohort study assesses the regulatory context, pivotal design characteristics, and postmarket requirements and commitments of novel drugs approved by the US Food and Drug Administration (FDA) in 2020 to characterize the state of evidence at the time of approval.
JAMA Netw Open. 2022;5(5):e2212454. doi:10.1001/jamanetworkopen.2022.12454
NEUROLOGY
Jing Yuan, PhD; Minghui Li, PhD; Yang Liu, MD; et al.
This cross-sectional study examines hospital arrival time and use of ambulances following implementation of a community education program to increase recognition of stroke.
JAMA Netw Open. 2022;5(5):e2212674. doi:10.1001/jamanetworkopen.2022.12674
PUBLIC HEALTH
Lydia W. Y. Fung, MPH; Jiaxi Zhao, MSc; Vincent K. C. Yan, BPharm; et al.
This survey study examines the preferences of staff and students at the University of Hong Kong regarding receipt of the COVID-19 vaccine.
has active quiz
JAMA Netw Open. 2022;5(5):e2212681. doi:10.1001/jamanetworkopen.2022.12681
GLOBAL HEALTH
Omar Karlsson, PhD; Rockli Kim, ScD; Andreas Hasman, DPhil; et al.
This cross-sectional study investigates all-cause mortality among children younger than 5 years in 77 low- and middle-income countries and compares the mortality rates among children younger than 2 years with those aged 2 to 4 years.
JAMA Netw Open. 2022;5(5):e2212692. doi:10.1001/jamanetworkopen.2022.12692
OBSTETRICS AND GYNECOLOGY
Mark A. Clapp, MD, MPH; Alexander Melamed, MD, MPH; Taylor S. Freret, MD; et al.
This cross-sectional study of neonates at risk for a late-preterm birth assesses whether new evidence on the benefit of steroid administration is associated with changes in clinical practice and neonatal outcomes.
JAMA Netw Open. 2022;5(5):e2212702. doi:10.1001/jamanetworkopen.2022.12702
CRITICAL CARE MEDICINE
Luca Molinari, MD; Gaspar Del Rio-Pertuz, MD; Ali Smith, BA; et al.
This cohort study examines associations between urinary levels of 2 cell-cycle arrest biomarkers and 30-day survival among patients with septic shock who developed acute kidney injury staged based on kidney function.
JAMA Netw Open. 2022;5(5):e2212709. doi:10.1001/jamanetworkopen.2022.12709
NEUROLOGY
Maria Florencia Iulita, PhD; Diana Garzón Chavez, RN; Maria Klitgaard Christensen, PhD; et al.
This meta-analysis assesses whether the variability in symptom onset of Alzheimer disease in Down syndrome is similar to autosomal dominant Alzheimer disease and its association with mortality.
JAMA Netw Open. 2022;5(5):e2212910. doi:10.1001/jamanetworkopen.2022.12910
PHYSICAL MEDICINE AND REHABILITATION
Jennifer S. Brach, PhD, PT; Subashan Perera, PhD; Valerie Shuman, DPT; et al.
This randomized clinical trial examines whether the addition of timing and coordination training to a standard exercise program for strength and endurance improved walking among community-dwelling older adults more than strength and endurance training alone.
JAMA Netw Open. 2022;5(5):e2212921. doi:10.1001/jamanetworkopen.2022.12921
SURGERY
Huiyu Deng, PhD; Zahra Eftekhari, MS; Cameron Carlin, MS; et al.
This prognostic study of US patients who underwent cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy develops and validates a model for predicting major postoperative complications using machine learning technology.
JAMA Netw Open. 2022;5(5):e2212930. doi:10.1001/jamanetworkopen.2022.12930
NEUROLOGY
Hussein M. Farag, PharmD, MSc, PhD; Ismaeel Yunusa, PharmD, PhD; Hardik Goswami, BPharm, MSc, PhD; et al.
This systematic review and network meta-analysis compares amitriptyline with Food and Drug Administration–approved treatments for fibromyalgia related to sleep, fatigue, and health-related quality of life outcomes.
JAMA Netw Open. 2022;5(5):e2212939. doi:10.1001/jamanetworkopen.2022.12939
ENVIRONMENTAL HEALTH
Sameed Ahmed M. Khatana, MD, MPH; Rachel M. Werner, MD, PhD; Peter W. Groeneveld, MD, MS
This cross-sectional study assesses the association between extreme heat and all-cause mortality rates in the US from 2008 to 2017.
JAMA Netw Open. 2022;5(5):e2212957. doi:10.1001/jamanetworkopen.2022.12957
EMERGENCY MEDICINE
Joris Nas, MD; Jos Thannhauser, PhD; Lara S. F. Konijnenberg, MD; et al.
This secondary analysis of a randomized clinical trial investigates bystander willingness to perform cardiopulmonary resuscitation on a stranger, theoretical knowledge retention, and dissemination of cardiopulmonary resuscitation awareness 6 months after undergoing short face-to-face or virtual reality training.
JAMA Netw Open. 2022;5(5):e2212964. doi:10.1001/jamanetworkopen.2022.12964
NUTRITION, OBESITY, AND EXERCISE
Maninder K. Kahlon, PhD; Nazan S. Aksan, PhD; Rhonda Aubrey, MHI; et al.
This randomized clinical trial investigates the effect of grocery gift cards and fruit and vegetable boxes provided to caregivers on healthfulness of diets among their children.
JAMA Netw Open. 2022;5(5):e2212973. doi:10.1001/jamanetworkopen.2022.12973
INFECTIOUS DISEASES
Su Youn Nam, MD, PhD; Seong Woo Jeon, MD, PhD; Hyun Seok Lee, MD, PhD; et al.
This cohort study investigates factors associated with anti–SARS-CoV-2 antibody levels.
has active quiz
JAMA Netw Open. 2022;5(5):e2212996. doi:10.1001/jamanetworkopen.2022.12996
GASTROENTEROLOGY AND HEPATOLOGY
Augustin G. L. Vannier, BA; Jessica E. S. Shay, MD, PhD; Vladislav Fomin, MD; et al.
This cohort study assesses the association between pharmacotherapy and the development of alcohol-associated liver disease in patients with alcohol use disorder.
JAMA Netw Open. 2022;5(5):e2213014. doi:10.1001/jamanetworkopen.2022.13014
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Invited Commentary
The Need for Integrating Addiction Medicine and Hepatology
Lorenzo Leggio, MD, PhD; M. Katherine Jung, PhD
JAMA Netw Open
ONCOLOGY
Timothy A. Yap, MD, PhD; Arya Ashok, PhD; Jessica Stoll, MS; et al.
This cross-sectional study examines the prevalence of germline findings in patients undergoing tumor/normal matched sequencing among cancer types lacking guidelines.
JAMA Netw Open. 2022;5(5):e2213070. doi:10.1001/jamanetworkopen.2022.13070
OCCUPATIONAL HEALTH
Liselotte N. Dyrbye, MD, MHPE; Colin P. West, MD, PhD; Christine A. Sinsky, MD; et al.
This cross-sectional study examines the occurrence of mistreatment of and discrimination toward physicians by patients, families, and visitors by physician characteristics and the association between such interactions and experiencing burnout.
JAMA Netw Open. 2022;5(5):e2213080. doi:10.1001/jamanetworkopen.2022.13080
HEALTH POLICY
Scott Fruhan, MD; Corey B. Bills, MD, MPH
This nonrandomized clinical trial assesses the association of an automated telephone call 2 days after emergency department discharge with the likelihood of an unplanned emergency department revisit at both 72 hours and 7 days after the index visit and with perceived care metrics measured at 14 days.
JAMA Netw Open. 2022;5(5):e2213154. doi:10.1001/jamanetworkopen.2022.13154
DIVERSITY, EQUITY, AND INCLUSION
Élan Burton, MD, MHA; Brenda Flores, BA; Barbara Jerome, MPH; et al.
This qualitative study assesses whether bias exists in patient safety reporting systems based on the gender, race and ethnicity, or faculty rank of the physician who is the subject of the event report.
JAMA Netw Open. 2022;5(5):e2213234. doi:10.1001/jamanetworkopen.2022.13234
PEDIATRICS
Sohyeon Kwon, MPH; Rockli Kim, ScD; Jong-Tae Lee, PhD; et al.
This cross-sectional study uses data from the Korea Youth Risk Behavior Web-Based Survey to examine the associations of duration of smartphone use and types of content most frequently accessed via smartphone with body image distortion and weight loss behaviors in Korean adolescents.
JAMA Netw Open. 2022;5(5):e2213237. doi:10.1001/jamanetworkopen.2022.13237
PUBLIC HEALTH
Amanda M. Fretts, PhD, MPH; Stanley L. Hazen, MD, PhD; Paul Jensen, PhD, MPH; et al.
This cohort study examines the associations of serial measures of plasma trimethylamine N-oxide and related metabolites with the risk of total and cause-specific death, including cardiovascular and noncardiovascular–related death, among older adults enrolled in the Cardiovascular Health Study.
JAMA Netw Open. 2022;5(5):e2213242. doi:10.1001/jamanetworkopen.2022.13242
ENVIRONMENTAL HEALTH
Le-Bing Wang, MS; Yan-Chen Gong, MS; Qiu-Ling Fang, MS; et al.
This cross-sectional study investigates the associations between exposure to outdoor artificial light at night and sleep disorders among a general population of Chinese children.
JAMA Netw Open. 2022;5(5):e2213247. doi:10.1001/jamanetworkopen.2022.13247
INFECTIOUS DISEASES
Arvid Edén, MD, PhD; Anna Grahn, MD, PhD; Daniel Bremell, MD, PhD; et al.
This cross-sectional study assesses whether viral antigens are detectable in the cerebrospinal fluid of patients with COVID-19 and compares cerebrospinal fluid biomarker profiles of patients with and without neurologic symptoms and with moderate vs severe COVID-19.
has active quiz
JAMA Netw Open. 2022;5(5):e2213253. doi:10.1001/jamanetworkopen.2022.13253
COMPLEMENTARY AND ALTERNATIVE MEDICINE
Yuhang Zhu, MS; Fangfang Wang, PhD; Jue Zhou, PhD; et al.
This randomized clinical trial evaluates urinary retention, uterine contraction pain, depressive symptoms, and lactation after acupoint hot compress treatment in women during their early postpartum period.
JAMA Netw Open. 2022;5(5):e2213261. doi:10.1001/jamanetworkopen.2022.13261
GLOBAL HEALTH
Gandolina Melhem, BS; Chris A. Rees, MD, MPH; Bruno F. Sunguya, MD, MSc, PhD; et al.
This cross-sectional study examines the association of having editorial staff members affiliated with low- and middle-income countries with publications reporting research from low- and middle-income countries in leading biomedical journals.
JAMA Netw Open. 2022;5(5):e2213269. doi:10.1001/jamanetworkopen.2022.13269
DIVERSITY, EQUITY, AND INCLUSION
Kathryn S. Smith, BS; Jennifer B. Bakkensen, MD; Anne P. Hutchinson, MD; et al.
This qualitative study assesses fertility knowledge and concerns and evaluates barriers to family building and impact on academic attrition reported by female physicians.
JAMA Netw Open. 2022;5(5):e2213337. doi:10.1001/jamanetworkopen.2022.13337
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Invited Commentary
Supporting Physicians Along the Entire Journey of Fertility and Family Building
Ariela L. Marshall, MD; Arghavan Salles, MD, PhD
JAMA Netw Open
OBSTETRICS AND GYNECOLOGY
Maria C. Cusimano, MD, PhD; Nancy N. Baxter, MD, PhD; Rinku Sutradhar, PhD; et al.
This cohort study examines the rates of severe maternal and neonatal morbidity in physicians compared with nonphysicians in Ontario, Canada.
JAMA Netw Open. 2022;5(5):e2213521. doi:10.1001/jamanetworkopen.2022.13521
DIVERSITY, EQUITY, AND INCLUSION
Laurent G. Glance, MD; Eeshwar K. Chandrasekar, MD, MPH; Ernie Shippey, MS; et al.
This cross-sectional study of adults undergoing major surgery evaluates whether racial disparities in access to surgical care occurred during the first wave of the COVID-19 pandemic.
has active quiz
JAMA Netw Open. 2022;5(5):e2213527. doi:10.1001/jamanetworkopen.2022.13527
ENVIRONMENTAL HEALTH
Antonio Fernando Boing, PhD; Priyanka deSouza, PhD; Alexandra Crispim Boing, PhD; et al.
This cross-sectional study assesses associations among fine particulate matter 2.5 μm or smaller, age-specific mortality risk, and socioeconomic status.
JAMA Netw Open. 2022;5(5):e2213540. doi:10.1001/jamanetworkopen.2022.13540
NEUROLOGY
Niels Secher, MD, PhD; Kasper Adelborg, MD, PhD; Péter Szentkúti, MSc; et al.
This cohort study uses data from Danish medical registries to examine the short-term and long-term risks of common neurologic and psychiatric outcomes for patients after hospitalization for cardiac arrest.
JAMA Netw Open. 2022;5(5):e2213546. doi:10.1001/jamanetworkopen.2022.13546
ONCOLOGY
Chan Shen, PhD; Daniel Tannenbaum, MD; Robert Horn, MD; et al.
This systematic review examines the trial characteristics and cumulative progress of phase 3 clinical trials of systemic therapy for metastatic colorectal cancer over the last 3 decades and assesses the associated outcomes reported in the Surveillance, Epidemiology and End Results (SEER) database.
JAMA Netw Open. 2022;5(5):e2213588. doi:10.1001/jamanetworkopen.2022.13588
INFECTIOUS DISEASES
Jiwon Jung, MD; Ji Yeun Kim, PhD; Heedo Park, MS; et al.
This cohort study compares the secondary attack rate and infectious viral shedding kinetics of SARS-CoV-2 in fully vaccinated vs partially vaccinated and unvaccinated individuals.
has active quiz
JAMA Netw Open. 2022;5(5):e2213606. doi:10.1001/jamanetworkopen.2022.13606
HEALTH POLICY
Zixuan Zhao, PhD; Youqing Wang, MD; Weijia Wu, PhD; et al.
This economic evaluation compares the cost-effectiveness of lung cancer screening strategies using low-dose computed tomography (LDCT) and a plasma-based biomarker or LDCT alone in a simulated population of Chinese adults with a history of smoking.
JAMA Netw Open. 2022;5(5):e2213634. doi:10.1001/jamanetworkopen.2022.13634
PULMONARY MEDICINE
Tapio Paljarvi, PhD; Julian Forton, PhD; Sierra Luciano, BA; et al.
This cohort study investigates the association of montelukast treatment with adverse neuropsychiatric outcomes among patients with asthma or allergic rhinitis.
JAMA Netw Open. 2022;5(5):e2213643. doi:10.1001/jamanetworkopen.2022.13643
EMERGENCY MEDICINE
Matthew P. Czaja, MPH; Chadd K. Kraus, DO, DrPH; Su Phyo, BS; et al.
This case series evaluates the injury characteristics, outcomes, and resource use among individuals who have sustained nonfatal injuries in civilian public mass shootings.
JAMA Netw Open. 2022;5(5):e2213737. doi:10.1001/jamanetworkopen.2022.13737
DIABETES AND ENDOCRINOLOGY
Tegveer S. Uppal, MPH; Puneet Kaur Chehal, MA, PhD; Gail Fernandes, MPH; et al.
This cross-sectional study uses data from the Nationwide Emergency Department Sample to estimate recent national- and state-level trends in diabetes-related emergency department use overall and by race and ethnicity, rural or urban location, and insurance status.
JAMA Netw Open. 2022;5(5):e2213867. doi:10.1001/jamanetworkopen.2022.13867
NEUROLOGY
Claudia Schwarz, PhD; Gloria S. Benson, PhD; Nora Horn, MD; et al.
This randomized clinical trial of older adults in a German clinical research center examines the effectiveness of spermidine as a dietary supplement over 12 months for improving memory and other key measures of cognitive performance compared with placebo.
JAMA Netw Open. 2022;5(5):e2213875. doi:10.1001/jamanetworkopen.2022.13875
CARDIOLOGY
Mette Søgaard, DVM, PhD; Flemming Skjøth, MSc, PhD; Peter B. Nielsen, MPH, PhD; et al.
This cohort study investigates the thromboembolic risks associated with atrial fibrillation (AF) in patients with pneumonia, assesses the risk of recurrent AF, and examines the association of initiation of anticoagulation therapy with new-onset AF.
JAMA Netw Open. 2022;5(5):e2213945. doi:10.1001/jamanetworkopen.2022.13945
OBSTETRICS AND GYNECOLOGY
Deanna Teoh, MD, MS; Gwiwon Nam, BA; Danielle A. Aase, MD; et al.
This cohort study evaluates whether human papillomavirus (HPV) vaccination is associated with decreased positive predictive value for abnormal cervical cytology.
JAMA Netw Open. 2022;5(5):e2214020. doi:10.1001/jamanetworkopen.2022.14020
ONCOLOGY
Sanjay Popat, PhD; Stephen V. Liu, MD; Nicolas Scheuer, MSc; et al.
This cohort study compares the overall survival between patients who currently or formerly smoked with patients who never smoked and initiated pembrolizumab monotherapy as first-line treatment for advanced non–small lung cancer.
JAMA Netw Open. 2022;5(5):e2214046. doi:10.1001/jamanetworkopen.2022.14046
PEDIATRICS
Anne M. Butler, PhD; Derek S. Brown, PhD; Michael J. Durkin, MD, MPH; et al.
This cohort study evaluates the comparative safety and health care expenditures of inappropriate vs appropriate oral antibiotic prescriptions for common outpatient pediatric infections.
JAMA Netw Open. 2022;5(5):e2214153. doi:10.1001/jamanetworkopen.2022.14153
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Invited Commentary
Appropriate Antibiotic Prescribing—The Safer and Less Expensive Choice
Michael J. Smith, MD, MSCE; Bethany A. Wattles, PharmD, MHA
JAMA Netw Open
PUBLIC HEALTH
Andrew D. Kerkhoff, MD, PhD; Susana Rojas; Douglas Black, BA; et al.
This health care improvement study examines the effectiveness of integrating hemoglobin A1c testing for diabetes and prediabetes into a low-barrier COVID-19 testing site in a Latinx community in a large US city.
has active quiz
JAMA Netw Open. 2022;5(5):e2214163. doi:10.1001/jamanetworkopen.2022.14163
INFECTIOUS DISEASES
Thu Nguyen-Anh Tran, MSc; Nathan B. Wikle, PhD; Fuhan Yang, MSc; et al.
This case series assesses population-level immunity to SARS-CoV-2 during March 2020 through May 2021 in Rhode Island, Massachusetts, and Connecticut.
has active quiz
JAMA Netw Open. 2022;5(5):e2214171. doi:10.1001/jamanetworkopen.2022.14171
PUBLIC HEALTH
Chi Yan Leung, MD, MHS, PhD; Hsi-Lan Huang, MD, MHS, PhD; Sarah Krull Abe, PhD; et al.
This cohort study examines the association of marital status with total and cause-specific mortality in Asian populations.
JAMA Netw Open. 2022;5(5):e2214181. doi:10.1001/jamanetworkopen.2022.14181
GASTROENTEROLOGY AND HEPATOLOGY
Majed Almaghrabi, MBBS; Mandark Gandhi, MD, MSc; Leonardo Guizzetti, PhD; et al.
This systematic review and meta-analysis compares 4 lower gastrointestinal bleeding risk scores based on prognostic performance.
JAMA Netw Open. 2022;5(5):e2214253. doi:10.1001/jamanetworkopen.2022.14253
INFECTIOUS DISEASES
Jonathan D. Baghdadi, MD, PhD; Deborah Korenstein, MD; Lisa Pineles, MA; et al.
This survey study assesses whether certain attitudes and characteristics of primary care clinicians are associated with a predisposition to prescribe antibiotics for asymptomatic bacteriuria.
JAMA Netw Open. 2022;5(5):e2214268. doi:10.1001/jamanetworkopen.2022.14268
OBSTETRICS AND GYNECOLOGY
Malia S. Q. Murphy, PhD; Robin Ducharme, MSc; Steven Hawken, PhD; et al.
This cohort study examines the incidence of autism spectrum disorder at age 18 months among the offspring of mothers who received epidural or combined spinal-epidural analgesia during labor.
JAMA Netw Open. 2022;5(5):e2214273. doi:10.1001/jamanetworkopen.2022.14273
SUBSTANCE USE AND ADDICTION
Kao-Ping Chua, MD, PhD; Jennifer F. Waljee, MD, MS; Michael A. Smith, PharmD, BCPS; et al.
This cross-sectional study estimates the prevalence of opioid prescriptions from US surgeons and dentists dispensed more than 30 days after writing and evaluates changes as a result of US state laws enacted to shorten the maximum period between opioid prescription writing and dispensing.
JAMA Netw Open. 2022;5(5):e2214311. doi:10.1001/jamanetworkopen.2022.14311
CARDIOLOGY
Sean D. Pokorney, MD, MBA; Noelle Cocoros, DSc, MPH; Hussein R. Al-Khalidi, PhD; et al.
This randomized clinical trial investigates whether an educational intervention directed to patients and their clinicians stimulates the use of oral anticoagulants in patients with atrial fibrillation (AF) who are not receiving oral anticoagulants (OACs).
JAMA Netw Open. 2022;5(5):e2214321. doi:10.1001/jamanetworkopen.2022.14321
PEDIATRICS
Yulika Yoshida-Montezuma, MPH; Branavan Sivapathasundaram, MPH; Hilary K. Brown, PhD; et al.
This cohort study assesses whether late preterm birth and size for gestational age are associated with cardiometabolic risk in childhood among participants aged 3 to 12 years.
JAMA Netw Open. 2022;5(5):e2214379. doi:10.1001/jamanetworkopen.2022.14379
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Invited Commentary
Late Preterm Birth and the Risk of Cardiometabolic Disease
Lauren Iacono, DO; Molly O. Regelmann, MD
JAMA Netw Open
NEPHROLOGY
Xiaocen Fu, MD; Hong Ren, MD; Jingyuan Xie, MD; et al.
This cohort study investigates the prevalence of nighttime masked uncontrolled hypertension and its associations with cardiovascular and kidney outcomes in patients with chronic kidney disease (CKD) who were not receiving dialysis.
JAMA Netw Open. 2022;5(5):e2214460. doi:10.1001/jamanetworkopen.2022.14460
HEALTH INFORMATICS
Finly J. Zachariah, MD; Lorenzo A. Rossi, PhD; Laura M. Roberts, MS; et al.
This prognostic study compares the outcomes of oncologists vs a machine learning model in predicting mortality in patients with advanced metastatic cancer.
JAMA Netw Open. 2022;5(5):e2214514. doi:10.1001/jamanetworkopen.2022.14514
PUBLIC HEALTH
Yun Wang, PhD; Noel Eldridge, MS; Mark L. Metersky, MD; et al.
This cross-sectional study evaluates whether patients with pneumonia admitted to hospitals with higher risk-standardized readmission rates had a higher risk of adverse events.
JAMA Netw Open. 2022;5(5):e2214586. doi:10.1001/jamanetworkopen.2022.14586
CARDIOLOGY
Fangju Su, MD; Chao Gao, MD, PhD; Jianzheng Liu, BSc; et al.
This cohort study assesses the procedural success and major adverse event rates associated with left atrial appendage occlusion procedures among patients in China.
JAMA Netw Open. 2022;5(5):e2214594. doi:10.1001/jamanetworkopen.2022.14594
EMERGENCY MEDICINE
Amelia Xin Chun Goh; Jie Cong Seow; Melvin Yong Hao Lai; et al.
This meta-analysis and systematic review assesses whether treatment at a high-volume center is associated with better survival and neurological outcomes in patients with nontraumatic out-of-hospital cardiac arrest (OHCA).
JAMA Netw Open. 2022;5(5):e2214639. doi:10.1001/jamanetworkopen.2022.14639
GERIATRICS
Taya A. Collyer, PhD; Anne M. Murray, MD; Robyn L. Woods, PhD; et al.
This cohort study using data from a large multinational clinical trial of older adults examines the association of dementia risk with a coinciding decline in gait and memory compared with domain-specific prognostic models.
JAMA Netw Open. 2022;5(5):e2214647. doi:10.1001/jamanetworkopen.2022.14647
PUBLIC HEALTH
Andi Camden, MPH; Teresa To, PhD; Joel G. Ray, MD, MSc; et al.
This cross-sectional study evaluates the association between the category of opioid use among pregnant people and subsequent overdose or death.
has audio
JAMA Netw Open. 2022;5(5):e2214688. doi:10.1001/jamanetworkopen.2022.14688
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Audio:
Categorization of Opioid Use Among Pregnant People, and Association With Overdose or Death
PUBLIC HEALTH
Sharon Zeng, BA; Kenley M. Pelzer, PhD; Robert D. Gibbons, PhD; et al.
This cohort study assesses the association between zip code–level vaccination coverage and COVID-19 mortality in Chicago, Illinois.
has active quiz
JAMA Netw Open. 2022;5(5):e2214753. doi:10.1001/jamanetworkopen.2022.14753
GENETICS AND GENOMICS
Walid Abuhammour, MD; Lemis Yavuz, MD; Ruchi Jain, PhD; et al.
This cohort study of patients with multisystem inflammatory syndrome in children assesses whether rare deleterious genetic variants that affect immune-related genes are enriched in patients of Middle Eastern origin.
JAMA Netw Open. 2022;5(5):e2214985. doi:10.1001/jamanetworkopen.2022.14985
HEALTH INFORMATICS
Tong Wang, BS; Xu Zheng, BS; Jun Liang, MS; et al.
This cross-sectional study assesses factors correlated with satisfaction and dissatisfaction with mobile health apps for weight loss among Chinese users and examines whether differences in these correlations are asymmetric.
JAMA Netw Open. 2022;5(5):e2215014. doi:10.1001/jamanetworkopen.2022.15014
NEUROLOGY
Julián N. Acosta, MD; Cameron P. Both, BS; Cyprien Rivier, MD, MS; et al.
This genetic association study assesses the associations of observed and genetic cardiovascular health profiles with brain health among asymptomatic adults.
JAMA Netw Open. 2022;5(5):e2215328. doi:10.1001/jamanetworkopen.2022.15328
SUBSTANCE USE AND ADDICTION
Shivani Mathur Gaiha, PhD; Crystal Lin, MSc; Lauren Kass Lempert, JD, MPH; et al.
This cross-sectional study evaluates nonnicotine e-cigarette use patterns, including common flavors, brands, and ingredients.
JAMA Netw Open. 2022;5(5):e2216194. doi:10.1001/jamanetworkopen.2022.16194
GERIATRICS
Talia Salzman, MSc; Yanina Sarquis-Adamson, PhD; Surim Son, MSc; et al.
This systematic review and meta-analysis evaluates whether multidomain interventions, composed of 2 or more interventions, are associated with greater improvements in cognition among older adults with mild cognitive impairment (MCI) than a single intervention on its own.
JAMA Netw Open. 2022;5(5):e226744. doi:10.1001/jamanetworkopen.2022.6744
PSYCHIATRY
Colm Healy, PhD; Ross Brannigan, PhD; Niamh Dooley, MSc; et al.
This cohort study of 2 longitudinal cohorts of Irish children and adolescents develops a schema of person-centered psychopathological profiles based on evaluative questionnaire data.
JAMA Netw Open. 2022;5(5):e229601. doi:10.1001/jamanetworkopen.2022.9601
ONCOLOGY
Xinran Ma, MS; Lawrence Bellomo, BS; Ian Hooley, BS; et al.
This cohort study examines the feasibility of assessing solid tumor response to treatment from electronic health record (EHR) documentation and the concordance between EHR-based assessment and clinical trial standards.
JAMA Netw Open. 2022;5(5):e229655. doi:10.1001/jamanetworkopen.2022.9655
NUTRITION, OBESITY, AND EXERCISE
Kristina H. Lewis, MD, MPH, SM; Stephanie Argetsinger, MS, MPH; David E. Arterburn, MD, MPH; et al.
This comparative effectiveness study evaluates the associations of sleeve gastrectomy and Roux-en-Y gastric bypass with ambulatory health care costs and use for 4 years after surgery.
JAMA Netw Open. 2022;5(5):e229661. doi:10.1001/jamanetworkopen.2022.9661
PUBLIC HEALTH
Mehrnoosh Soori, PhD, MSc; Elizabeth A. Platz, ScD, MPH; Otis W. Brawley, MD; et al.
This cross-sectional study evaluates the consistency of state comprehensive cancer control plan objectives compared with the 2016 US Preventive Services Task Force (USPSTF) recommendations for the age and frequency that women should undergo mammography.
JAMA Netw Open. 2022;5(5):e229706. doi:10.1001/jamanetworkopen.2022.9706
SURGERY
Peter C. Minneci, MD, MHSc; Erinn M. Hade, PhD; Lindsay A. Gil, MD; et al.
This planned secondary analysis of a nonrandomized clinical trial investigates the factors associated with the failure of nonoperative management of pediatric appendicitis and compares patient-reported outcomes between patients whose treatment succeeded and those whose treatment failed.
JAMA Netw Open. 2022;5(5):e229712. doi:10.1001/jamanetworkopen.2022.9712
HEALTH POLICY
Lewei Duan, PhD, MS, MA; Ming-Sum Lee, MD, PhD; John L. Adams, PhD; et al.
This cohort study examines changes in naloxone and opioid prescribing rates in the outpatient setting at 1 integrated health care system after the launch of decision-support prompts in the electronic health record (HER) in compliance with the State of California Assembly Bill 2760.
JAMA Netw Open. 2022;5(5):e229723. doi:10.1001/jamanetworkopen.2022.9723
PSYCHIATRY
William V. Bobo, MD, MPH; Brandon R. Grossardt, MS; Sanya Virani, MD, MPH; et al.
This cohort study assesses the risk and rate of accumulating chronic conditions in people with depression, anxiety, or comorbid depression and anxiety stratified by age and sex.
JAMA Netw Open. 2022;5(5):e229817. doi:10.1001/jamanetworkopen.2022.9817
CARDIOLOGY
Yuan Lu, ScD; Shu-Xia Li, PhD; Yuntian Liu, MPH; et al.
This case-control study assesses the sex-specific associations of demographic, clinical, and psychosocial risk factors with first acute myocardial infarction among adults younger than 55 years, overall, and by infarction subtype.
JAMA Netw Open. 2022;5(5):e229953. doi:10.1001/jamanetworkopen.2022.9953
OPHTHALMOLOGY
Li Dong, MD; Wanji He, PhD; Ruiheng Zhang, MSc; et al.
This diagnostic study develops and prospectively validates a deep learning algorithm that uses ocular fundus images to recognize numerous retinal diseases in a clinical setting at 65 screening centers in 19 Chinese provinces.
JAMA Netw Open. 2022;5(5):e229960. doi:10.1001/jamanetworkopen.2022.9960
ORTHOPEDICS
Laurie C. Yousman, BS; Walter R. Hsiang, MD, MBA; Akshay Khunte, BS; et al.
This survey study assesses out-of-pocket costs and factors associated with these costs for a first visit to a musculoskeletal urgent care center for uninsured and underinsured patients in the US.
JAMA Netw Open. 2022;5(5):e229968. doi:10.1001/jamanetworkopen.2022.9968
HEALTH POLICY
LeChauncy Woodard, MD, MPH; Amber B. Amspoker, PhD; Natalie E. Hundt, PhD; et al.
This randomized clinical trial evaluates the effectiveness of the Empowering Patients in Chronic Care intervention compared with usual care when delivered by clinicians engaged in routine care of patients with type 2 diabetes.
JAMA Netw Open. 2022;5(5):e229975. doi:10.1001/jamanetworkopen.2022.9975