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April 2010

Long-term Follow-up of Monomelic Amyotrophy of the Upper Limb

Author Affiliations

Author Affiliation: Department of Neurology, Institute of Human Behaviour and Allied Sciences, Dilshad Gardens, New Delhi, India.

Arch Neurol. 2010;67(4):517-518. doi:10.1001/archneurol.2010.32

I read with great interest the article by Van den Berg-Vos et al1 that described a prospective study of 32 patients with lower motor neuron syndrome with duration of disease of 4 years or more who were followed up for 72 months to identify the group of patients who have either slow progression or attain a stationary course for many years and do not progress to having amyotrophic lateral sclerosis. The authors describe a favorable prognosis in 8 patients with segmental distribution of muscle involvement. No significant change in muscle strength was observed but there was spread to adjoining segments in one patient and to contralateral side in another.

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