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September 2010

Anxiety as Initial Diagnosis in Opsoclonus Myoclonus Syndrome

Author Affiliations

Author Affiliations: Departments of Neurology (Drs Korn-Lubetzki and Birmanns) and Psychiatry (Dr Jaworowski), Shaare Zedek Medical Center, Jerusalem, Israel.

Arch Neurol. 2010;67(9):1154-1155. doi:10.1001/archneurol.2010.192

We read with interest the article by Kurian et al1 describing a young woman with opsoclonus-myoclonus syndrome (OMS) in the context of an anti–N-methyl-D-aspartate receptor (NMDAR) encephalitis. The clinical signs at presentation were speech difficulties, hypophonia, anxiety, and tremulous eye and head movement followed by increasing gait instability. She was diagnosed with depression and initially hospitalized in the psychiatric division.