In their article on deep brain stimulation (DBS) of the internal pallidum (GPi) for myoclonus-dystonia (M-D) due to ε-sarcoglycan (SGCE) mutations, Azoulay-Zyss and coauthors1 conclude that DBS’s effect on psychiatric comorbidity needs to be studied.
We describe 5 patients with SGCE –M-D (4 men; mean age, 37 years; range, 18-50 years) who underwent bilateral GPi-DBS for their invalidating motor symptoms.