In Reply We thank Dr Macerollo for the interesting commentary on our article.1 Mutations in the glucocerebrosidase (GBA) gene are widely recognized to be an important and common genetic risk factor for Parkinson disease (PD),2 and they are found in British patients with PD at a higher frequency than any other known PD-associated gene.3
Beavan M, Schapira AHV. Glucocerebrosidase Gene Mutation and Preclinical Markers of Parkinson Disease—Reply. JAMA Neurol. 2015;72(6):724. doi:10.1001/jamaneurol.2015.0484
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