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Comment & Response
June 2015

Glucocerebrosidase Gene Mutation and Preclinical Markers of Parkinson Disease—Reply

Author Affiliations
  • 1Department of Clinical Neurosciences, UCL Institute of Neurology, University College London, London, England
JAMA Neurol. 2015;72(6):724. doi:10.1001/jamaneurol.2015.0484

In Reply We thank Dr Macerollo for the interesting commentary on our article.1 Mutations in the glucocerebrosidase (GBA) gene are widely recognized to be an important and common genetic risk factor for Parkinson disease (PD),2 and they are found in British patients with PD at a higher frequency than any other known PD-associated gene.3