A woman in her 50s with multiple sclerosis (MS) presented with a 5-year history of daily involuntary tongue movements that began abruptly approximately 1 year from the onset of MS symptoms. She reported that the involuntary tongue movements mostly occurred with the mouth closed and disappeared while she was eating or speaking. The movements distracted the patient greatly at night prior to falling asleep. A sensory trick of placing a straw between the teeth diminished the movements. The patient reported pain and a sensation of dripping pus on the right side of the face, but there was no temporal association with the tongue movements. There was no history of exposure to neuroleptic agents.