The ability to assign clinical symptoms to specific anatomical structures of the nervous system is a mainstay of clinical neurologic practice. The second edition of the Color Atlas of Neurology by Reinhard Rohkamm aims at teaching the practical significance of neuroanatomic knowledge in clinical neurology following an incremental concept. First, the basic neuroanatomical structures and functional concepts of the human nervous system are outlined, followed by the leading symptoms of patients with neurological diseases and a depiction of major neurological disorders with a focus on the clinical picture. Additional comprehensive anatomical and clinical information is provided in numerous tables in an extensive appendix. I did not have access to the first edition of the book; hence, no statement can be made on possible differences between editions.