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June 2016

Cerebral Microbleeds and Thrombolysis: Clinical Consequences and Mechanistic Implications

Author Affiliations
  • 1Departments of Neurology and Pathology & Laboratory Medicine, University of California Irvine, Orange
JAMA Neurol. 2016;73(6):632-635. doi:10.1001/jamaneurol.2016.0576

Using intravenous thrombolysis in a stroke patient with cerebral microbleeds represents one of the most challenging clinical decisions in acute stroke neurology. In this setting, the implications of coexisting ischemic and hemorrhagic cerebrovascular disease (mixed cerebrovascular disease)1 must be confronted and urgently addressed. The clinical consequences of intervening or not intervening are profound.