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Comment & Response
July 2016

Association Between Body Mass Index and Parkinson Disease—Reply

Author Affiliations
  • 1Department of Neurology, Harvard Medical School, Boston, Massachusetts
  • 2Department of Neurology, Massachusetts General Hospital, Boston
  • 3Department of Neurological Sciences, College of Medicine, University of Vermont, Burlington
  • 4Department of Biostatistics, The University of Texas Health Science Center at Houston–UT Health
JAMA Neurol. 2016;73(7):892. doi:10.1001/jamaneurol.2016.1245

In Reply We wish to clarify that our study1 was not designed to look at nutritional status in Parkinson disease. The article that we cited by Paganoni et al2 on the association between body mass index and amyotrophic lateral sclerosis found a dose-dependent effect of body mass index on survival, rather than a threshold based on undernutrition as the letter suggests.2 We agree with Cardoso and colleagues that body mass index is not adequate to define the nutritional status of patients. We also agree that future research into the nutritional status of patients with Parkinson disease would be very valuable.