A Haitian woman in her 40s presented with generalized seizures during a visit to the United States. She noted 4 months of headaches, fatigue, and a 40-lb weight loss in addition to fevers during the week prior to her presentation. On arrival to the hospital, she had a body temperature of 103°F, was somnolent but arousable to voice, was minimally verbal, and only followed simple commands. Her tone was increased in her right upper extremity. A noncontrast head computed tomography scan revealed an ill-defined mass in the left parietal lobe with edema and mass effect causing midline shift. She started empirical treatment on vancomycin, ceftriaxone, and metronidazole for a possible brain abscess.