Neurofilament Protein and Antineurofilament Antibodies Following Traumatic Brain Injury

To the Editor Shahim et al¹ reported the finding that individuals with persistent mild traumatic brain injury (mTBI) (postconcussive syndrome) have increased levels of neurofilament light (NF-L) proteins in their spinal fluid that was suggestive of axonal white matter injury. The increase in NF-L proteins correlated with Rivermead Concussion scores and lifetime concussion events.