To the Editor Shahim et al1 reported the finding that individuals with persistent mild traumatic brain injury (mTBI) (postconcussive syndrome) have increased levels of neurofilament light (NF-L) proteins in their spinal fluid that was suggestive of axonal white matter injury. The increase in NF-L proteins correlated with Rivermead Concussion scores and lifetime concussion events.
Kornguth S. Neurofilament Protein and Antineurofilament Antibodies Following Traumatic Brain Injury. JAMA Neurol. 2017;74(3):363. doi:10.1001/jamaneurol.2016.5908
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