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April 2017

Circadian Rhythms and Chronotherapeutics—Underappreciated Approach to Improving Sleep and Wakefulness in Parkinson Disease

Author Affiliations
  • 1Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria
JAMA Neurol. 2017;74(4):387-388. doi:10.1001/jamaneurol.2016.5519

In this issue of JAMA Neurology, Videnovic and colleagues1 present a study using timed light therapy in patients with Parkinson disease. They exposed patients to bright or dim-red light twice daily over a 2-week period, and then they evaluated several measures of sleep, daytime sleepiness, and symptoms of the disease. Sleep was improved, daytime sleepiness decreased, and Parkinson-specific motor scores were reduced with light therapy. Light therapy also had positive effects on activities of daily living and behavior, specifically physical activity rhythms.

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