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Comment & Response
May 2017

Incorrect Data Used in Statistical Analyses

Author Affiliations
  • 1Department of Environmental Health Sciences, University of Michigan, Ann Arbor
  • 2Department of Neurology, University of Michigan, Ann Arbor
JAMA Neurol. 2017;74(5):611-612. doi:10.1001/jamaneurol.2016.6106

To the Editor On behalf of our coauthors, we write to explain errors that occurred in our article, “Association of Environmental Toxins With Amyotrophic Lateral Sclerosis,” which was published in the July 2016 issue of JAMA Neurology.1 The article reported our case-control study of occupational and residential exposures to 122 neurotoxic organic pollutants, including organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs), and polybrominated diphenyl ethers (PBDEs), that were assessed using a self-administered survey derived from the Agency for Toxic Substances and Disease Registry, the National Health and Nutrition Examination Survey, and the National Human Exposure Assessment Survey, as well as biological samples obtained from 156 patients with amyotrophic lateral sclerosis (ALS) and a control group of 128 individuals. The objective of the study was to evaluate the association of occupational exposures and environmental toxins with the risk for developing ALS in Michigan.

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