Intracerebral hemorrhage (ICH) represents approximately 10% to 15% of strokes and results in high mortality and severe disability in those who survive the event. Hypertension is the most prevalent among many risk factors for nontraumatic ICH. In prior retrospective and prospective studies,1 the spot sign seen on computed tomographic angiography (CTA) performed in the acute setting indicated active bleeding and early hematoma expansion. In addition, studies2,3 have demonstrated a strong correlation between the initial ICH volume and worse clinical outcomes, particularly with participants who have a positive spot sign on CTA.
Berthaud JV, Worrall BB. Can the Spot Sign Identify Who Benefits From Aggressive Blood Pressure Reduction in Intracerebral Hemorrhage? JAMA Neurol. 2017;74(8):905–907. doi:10.1001/jamaneurol.2017.1022
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: