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Comment & Response
November 2017

Overall Survival and Causes of Death in Neurodegeneration—An Overlooked and Underreported Theme

Author Affiliations
  • 1Huntington’s Disease Centre, Institute of Neurology, University College London, London, England
  • 2Instituto de Medicina Molecular, Lisbon, Portugal
  • 3Laboratory of Clinical Pharmacology and Therapeutics, Faculty of Medicine, University of Lisbon, Lisbon, Portugal
  • 4CNS–Campus Neurológico Senior, Torres Vedras, Portugal
JAMA Neurol. 2017;74(11):1379. doi:10.1001/jamaneurol.2017.2862

To the Editor We read with interest the work of Savica and colleagues1 on the survival and causes of death of synucleinopathies with parkinsonism. Research about the natural history of late-stage neurodegenerative diseases is frequently neglected even though it is extremely relevant for clinical care.2 There is also a general impression in the field that several aspects are shared across neurodegenerative diseases when it comes to late- and end-stage disease.

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