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April 2018

Time May Be of the Essence in the Treatment of Pediatric Patients With Refractory Convulsive Status Epilepticus

Author Affiliations
  • 1Division of Pediatric Neurology, Nationwide Children’s Hospital, Columbus, Ohio
JAMA Neurol. 2018;75(4):402-403. doi:10.1001/jamaneurol.2017.4028

Status epilepticus (SE) is a very common neurological emergency in children.1,2 Refractory convulsive SE (RCSE) is characterized by the persistence of convulsive seizures or evolution of the convulsive seizure to nonconvulsive seizures event after initial antiseizure treatment.3 Children presenting in RCSE account for a high percentage of morbidity and mortality.3-5 In one study, the mortality was 32% for children with RCSE.4