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Images in Neurology
November 2018

Association of Transsynaptic Degeneration of the Papez Circuit With Anterior Thalamic Encephalomalacia

Author Affiliations
  • 1Department of Radiology, Foothills Medical Center, University of Calgary, Cumming School of Medicine, Calgary, Alberta, Canada
JAMA Neurol. 2018;75(11):1437-1438. doi:10.1001/jamaneurol.2018.2262

A right-handed male adolescent presented with a history of staring spells and headache for the past 2 years. Episodes typically lasted for 5 minutes, with no head deviation or tonic-clonic movements. Some of the episodes were associated with an abnormal shrieking sound and stiffening of the body. There was no history of memory loss. His seizure semiology results were consistent with dyscognitive focal complex partial seizures. His birth and developmental history were unremarkable. No focal neurologic deficits were seen on examination. A computed tomography head study yielded normal results. An awake electroencephalogram did not show any abnormality.

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