Challenges in Defining Inappropriate Medication Use in Parkinson Disease Dementia

Parkinson disease is the second most common neurodegenerative disorder. Cognitive impairment is a major nonmotor feature of Parkinson disease, and most patients with Parkinson disease will meet the criteria for dementia in the second decade after diagnosis.¹ National prescribing trends for patients with Parkinson disease and dementia are not well studied in the United States, and available data often exclude geographic location, race/ethnicity, and sex. In this editorial, we review the findings of the study by Mantri et al¹ regarding patterns of antidementia medication use, and we address the challenges in defining and studying inappropriate medication prescribing in Parkinson disease.