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Comment & Response
November 26, 2018

Misinterpretation of Study Data

Author Affiliations
  • 1Department of Medicine (Neurology), University of Alberta, Edmonton, Alberta, Canada
  • 2Department of Neuroscience, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands
JAMA Neurol. Published online November 26, 2018. doi:10.1001/jamaneurol.2018.3668

To the Editor The recent Wilson et al study1 reported that next-generation sequencing served as a diagnostic tool for neurological infections. It also posited that data from our group2,3 reflected a contamination of the molecular biological reagents and not the presence of bacteria in surgically resected and autopsied brains. We take issue with this latter conclusion because it is based on several mistaken interpretations of our data.