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Comment & Response
November 26, 2018

Misinterpretation of Study Data—Reply

Author Affiliations
  • 1Weill Institute for Neurosciences, University of California, San Francisco
  • 2Department of Neurology, University of California, San Francisco
  • 3Department of Biochemistry and Biophysics, University of California, San Francisco
  • 4Chan Zuckerberg Biohub, San Francisco, California
JAMA Neurol. Published online November 26, 2018. doi:10.1001/jamaneurol.2018.3671

In Reply We thank Power and colleagues for their comments regarding our recent article1 on metagenomic next-generation sequencing (mNGS). In our article, we expressed concern that their recent reports of a brain microbiome may be confounded by environmental microbial–contaminating sequences in their mNGS data sets.2,3