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Comment & Response
January 2019

Overlooked Implications of Disturbed Sleep in Traumatic Brain Injury

Author Affiliations
  • 1Veterans Affairs Portland Health Care System, Oregon Health & Science University, Portland
  • 2San Antonio Military Health System, Department of Sleep Medicine, JBSA Lackland, Texas
JAMA Neurol. 2019;76(1):114-115. doi:10.1001/jamaneurol.2018.3738

To the Editor A recent propensity-matched cohort study of more than 350 000 veterans with and without traumatic brain injury (TBI) by Barnes et al1 found that mild TBI was associated with more than a 2-fold increase in the risk of dementia, yielding implications for long-term neurodegenerative consequences following TBI. This longitudinal study allowed for the power to detect associations and to adjust for a range of potential confounders, including other medical and psychiatric comorbidities. While we applaud the authors and feel the findings are important, we note a discrepancy in their report of comorbidities, specifically “sleep disorders” (ie, sleep apnea, insomnia, hypersomnia, parasomnia, and circadian rhythm disorders).

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