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Research Letter
April 29, 2019

Attitudes Toward Physician-Assisted Death From Individuals Who Learn They Have an Alzheimer Disease Biomarker

Author Affiliations
  • 1Department of Medical Ethics and Health Policy, University of Pennsylvania Perelman School of Medicine, Philadelphia
  • 2Department of Sociology, Princeton University, Princeton, New Jersey
  • 3Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia
JAMA Neurol. 2019;76(7):864-866. doi:10.1001/jamaneurol.2019.0797

Seven states have legalized physician-assisted death (PAD) for competent, terminally ill individuals; these criteria exclude persons with dementia (PWD). However, there is ethical and policy discussion around expanding access to PAD to people with Alzheimer disease (AD).1,2 Here, we present attitudes toward PAD of cognitively normal individuals enrolled in a clinical trial that required them to learn whether they have elevated amyloid-β, a biomarker that increases risk for cognitive decline owing to AD.3