A hypothetical 3-year-old child presents with new-onset ataxia. A magnetic resonance image of the brain is pursued, consisting of a single axial T1 slice that shows the ventricles to be normal in size. The child returns several weeks later, and owing to concern about the cerebellum, another single coronal T1 slice is obtained, which is also normal. A third scan later that month, this time a coronal T2 image including the basal ganglia, reveals bilateral injury. Further diagnostic tests proceed from there.
Identify all potential conflicts of interest that might be relevant to your comment.
Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.
Err on the side of full disclosure.
If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.
Not all submitted comments are published. Please see our commenting policy for details.
Mendelsohn BA. Imaging the Whole Genome in Diagnosing Neurologic Disorders. JAMA Neurol. 2019;76(12):1419–1420. doi:10.1001/jamaneurol.2019.3117
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.