A Chinese woman in her 40s presented to the emergency department with a reduced level of consciousness. She had a 5-year history of depression with apathy, insomnia, and suicidal tendencies, which was refractory to paroxetine and buspirone. For a few weeks prior to admission, her husband had noticed prominently nocturnal dyspnea. One week before admission, she developed headache, fever, and vomiting, which persisted until hospitalization. Soon after admission, she had a generalized seizure, and within 24 hours, she underwent intubation for status epilepticus.
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Chen H, Wu J, Irani SR. Distinctive Magnetic Resonance Imaging Findings in IgLON5 Antibody Disease. JAMA Neurol. Published online November 04, 2019. doi:https://doi.org/10.1001/jamaneurol.2019.3638
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