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Research Letter
May 11, 2020

Assessment of Genetic Association Between Parkinson Disease and Bipolar Disorder

Author Affiliations
  • 1Molecular Genetics Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland
JAMA Neurol. Published online May 11, 2020. doi:10.1001/jamaneurol.2020.0248

A recent systematic review and meta-analysis1 suggests that a previous diagnosis of bipolar disorder (BD) increases the likelihood of a subsequent diagnosis of idiopathic Parkinson disease (PD). Using data from the International Parkinson Disease Genomics Consortium (IPDGC) and the UK Biobank (UKBB), we assessed the possibility of a shared genetic etiology or association between PD and BD.

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