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Research Letter
June 22, 2020

Changing Causes of US Neurological Disease Mortality From 1999 to 2017

Author Affiliations
  • 1Department of Neurological Surgery, Mount Sinai Health System, New York, New York
JAMA Neurol. 2020;77(9):1175-1177. doi:10.1001/jamaneurol.2020.1878

The World Health Organization’s international Global Burden of Disease 2016 study1 noted a decrease in rates of age-standardized neurological disorder death from 1990 to 2015, with a significant increase in disease burden due to aging populations and population growth. Considerable US health care system investments into cardiovascular disease and cancer research have resulted in dramatic increases in overall health and survival while potentially increasing neurological diseases’ relative burden.2,3 We estimate neurological disease mortality rate trends at a population scale from January 1999 to December 2017 while investigating regionalized differences within the US.

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